How to determine the stage of breast cancer. How to determine the stage of cancer: modern diagnostic methods

  • The date: 15.04.2019

Alcoholism is chronic disease, which, like many others, has its own stages of development. To diagnose them, it is not at all necessary to go through countless diagnostic procedures and involve laboratory methods definitions. Most often, the degree of severity of dependence can be assessed with the naked eye, as evidenced by the symptoms at each stage. In order to characterize each of them, it is necessary to delve a little into the definition of the conditionally called zero stage, namely, the prerequisites and mechanisms for the formation of the disease.

How and why is alcohol addiction formed?

There are some of the most common reasons why alcoholism develops under "favorable" conditions. These include:

  • heredity and individual characteristics of the organism;
  • personality traits that act as a factor in the formation of addiction;
  • psychological condition– depression, apathy, stress;
  • early exposure to alcohol.

The disease is formed according to a typical pattern: at first, alcohol acts as a kind of legal drug, a way to relax, cheer up. Alcohol acts similarly to narcotic substances, moreover, they belong to different groups - dopamine and opiate. The former stimulate the psyche to create a repetition of the situation of obtaining pleasure, and the latter actually deliver it, irritating the areas of the brain responsible for this.

Regular drinking disrupts metabolic processes and the balance of substances: dopamine, glutamate (a stimulant nervous system), GABA (gamma-aminobutyric acid), which controls behavior. As a result, a person ceases to experience a sense of pleasure without alcoholic beverages, therefore he regularly receives “commands” from the brain for the appropriate behavior - to find and drink.

Can't persuade you to stop drinking?

We will help you do it for free! Leave a request:

help me

In order to know how to identify alcohol addiction in yourself or loved one, you should pay attention to the alarming "bells":

  1. The frequency of alcohol intake is increasing. There are new reasons to drink.
  2. There is a feeling of anticipation of the future feast or gatherings with alcohol.
  3. Forming a habit of using a large number alcohol during feasts, there is a need for an "additive".
  4. Alcohol can be consumed alone, the reasons for this may be far-fetched.
  5. Behavior in a state of intoxication changes - features that were previously unfamiliar to others appear.
  6. After drinking alcohol, memory lapses appear - it is difficult to restore the chronology of the events of the past day in the morning.
  7. Emotional dependence appears - if earlier alcohol was consumed in order to become good, now - so that it does not become bad.
  8. There is disorientation in time and space in a state of intoxication.
  9. Increasing cases of loss of things, documents, as well as cases associated with injuries.

The above signs can be combined into the stage of pre-alcoholism and prodromal - this is the beginning of the formation of dependence. In order to find out how to determine the stage of alcoholism further, it is necessary to characterize each of them.

The first stage of alcohol addiction

Drinking alcohol is an end in itself. This is characterized by the appearance of a strong desire to drink alcohol when emotional stress, a person unlearns how to relax and relieve stress in other ways. This also acts as a kind of justification - the patient explains his behavior by troubles at work, problems in the family or relationships with a soulmate.

Control over the amount drunk is lost, a person allows himself to get very drunk even if he was going to empty a couple of glasses. Drinking often ends in an alcoholic sleep.

The number of so-called alcoholic palimpsets is increasing - memory impairments in which the patient is not able to reproduce some of the details and events that happened to him during intoxication.

After drinking, a person can become aggressive, find fault with trifles, provoke conflicts. This causes the first difficulties in the social sphere.

Susceptibility to alcohol changes, the dose required to achieve the optimal effect increases. If a person knows how alcohol addiction manifests itself and understands the danger of the situation, he can temporarily stop drinking alcohol in order to demonstrate to himself control over his needs, but this is fraught with a deterioration in the psycho-emotional state and a subsequent breakdown. Then comes the second stage of the disease.

Signs of the second stage of alcohol addiction

Tolerance to alcohol increases significantly. Alcohol is required more and more, so often the patient begins to use cheaper alcohol and its surrogates. Palimpsets increase, which further weakens the control over the situation.

This stage of alcoholism is characterized by a withdrawal syndrome - a hangover. It is a symptom complex caused by the absence of the usual dose of the potion and manifests itself in a number of disorders of the nervous system (tremor, headache), heart and blood vessels ( high blood pressure, tachycardia), gastrointestinal tract(nausea, stomach pain), etc.

Most often, at this stage, a serious effect of alcohol consumption on the heart occurs in the form of violations of its work, since main muscle begins to experience increased stress.

For elimination unpleasant symptoms the person starts to get drunk. This most often turns into a binge, while a sharp refusal to use is fraught with alcoholic delirium (delirious tremens).

The first prerequisites for social problems at the previous stage develop into difficulties of a different scale: the patient is experiencing financial difficulties, so he often makes "stash" so as not to deprive himself of alcohol. There are difficulties at work, breaking ties with non-drinking friends and acquaintances, scandals in the family. The social circle narrows down to drinking buddies.

If a person loses his job, then when trying to stay in a new job, they end in failure - he is fired for absenteeism and an irresponsible attitude to duties.

The critical thinking of the patient weakens. He starts to think that everything is fine. At the same time, options are not ruled out that a person from time to time makes attempts to “go to the eyeballs” under pressure from family members. However, not everyone knows how to persuade a relative to undergo alcoholism treatment, so attempts to help end in failure.

The third stage of alcoholism: the path to psychosis

It is she who represents chronic phase diseases. The third stage is formed only 10-20 years after the start of use. It is characterized by an increase in the severity of symptoms of stages 1 and 2 and a sharp decrease in tolerance. For a state of intoxication, a small amount of alcohol becomes sufficient.

The nature of the use of alcohol is portioned: the reception begins after waking up and lasts all day, small doses are used, including at night. The patient's condition is drowsy and lethargic, consciousness is clouded. Reactions are strongly inhibited, severe memory lapses occur.

Withdrawal syndrome is more pronounced, therefore, after waking up, the patient immediately needs a dose of alcohol. From time to time the amount of alcohol is reduced to complete failure, there is a period of sobriety, but its duration is reduced over time.

In this case, the person no longer knows how to get rid of alcohol addiction on their own. Volitional qualities worsen, degradation sets in, ignoring personal hygiene, he looks untidy.

It is in this case that the likelihood of psychosis increases, alcoholic delirium develops multiple organ failure.

It is possible to overcome pathological craving for alcohol, but only at the initial stage of the disease. Despite this, not everyone manages to get rid of the disease on their own: willpower alone may not be enough for this. As a rule, critical thinking can begin to decline at the very beginning, which makes it difficult to understand the disease and prevent the right decision.

Save the life of yourself and your loved ones!

Leave a request and we will tell you step by step what you need to do!

Colon and rectal cancer develops in the lower part digestive tract(in the caecum/colon and rectum). It is a common disease (the third most common form of cancer) that claims many lives every year. After a patient is diagnosed with cancer, a stage (from I to IV) is determined, which describes the degree of development of the disease. To start appropriate treatment, you should know the stage of the cancer.

Steps

Determining the stage of cancer by symptoms

    Learn how cancer is diagnosed. Some people do not have any symptoms and are diagnosed only by tests and examinations (such as a stool test). After that, a colonoscopy is done (the doctor inserts a tube into the rectum to look at a possible tumor). In other people, cancer is detected by symptoms (which will be discussed below). In this case, a colonoscopy is also done, which confirms or refutes the diagnosis (colonoscopy is an accurate means of determining cancer, since the doctor can see the tumor with his own eyes).

    Know that there are usually no symptoms in stage 1 colon cancer. Chances are you won't know you have cancer until you've had an examination, such as a stool test (there may be blood in the stool, which is a symptom of cancer) or a colonoscopy (sometimes patients have this test during preventive purposes if the family had cases of the formation of polyps in the rectum, which often become precursors of cancer).

    Know the symptoms of the second and third stages. During this period, the tumor begins to grow and block the intestine or move to neighboring organs. Colon cancer symptoms include:

    • Blood in the stool (it may be visible, or it may be so small that you yourself will not notice)
    • Abdominal pain (it is caused by the tumor creating an obstruction in the intestine)
    • Changes in bowel function (infrequent bowel movements or constipation due to bowel obstruction)
    • Unusual tiredness, dizziness when standing (the doctor will order a blood test because often there are few red blood in the blood with colon cancer) blood cells, and hemoglobin drops due to blood loss associated with cancer)
  1. Know the symptoms of stage four cancer. In the fourth stage, the tumor spreads to other organs.

    • Most often, colon cancer spreads to the lungs (which makes breathing difficult), the bones (which causes bone pain), and the brain (which causes loss of consciousness, dizziness, and seizures).
    • In stage 4 cancer, patients often lose a lot of weight (many by 5 kilograms a month). This is due to loss of appetite, unpleasant sensations in the intestines and abdomen after eating, the acceleration of metabolism due to the formation of cancer cells.
    • Cancer cells have a faster metabolism than healthy cells. When cancer spreads, its cells consume more useful substances, and the person is left with fewer nutrients to support all bodily functions and a healthy weight.
  2. Know why staging cancer is critical. This will not only let your doctor and you know how serious it is, but it will also help you decide on the appropriate treatment.

    Tests to determine the stage of cancer

    1. Remember that examinations are extremely important in determining the stage of cancer. As mentioned above, determining the stage of cancer is necessary in order to choose the right treatment option.

      Know the difference between different types of cancer staging. There is a definition clinical stage disease, pathological stage, post-treatment stage. All these diagnostics are important in their own way.

Breast cancer is one of the most dangerous diseases among women. His prognosis is directly affected by the stages of breast cancer. At least 5 diagnostic methods are used to establish them. Early stages have a positive prognosis, while later ones require a long drug treatment, operations.

How is the stage determined?

A malignant neoplasm in the mammary gland has a tendency to change. The process of cancer progression is divided into several stages, which in medicine are called stages.

Arising out of epithelial cells, the cancer is placed either in lactiferous duct, or in one of the lobules. Subsequently, the tumor increases and begins to go beyond its place. Along with the growth of the tumor itself in the mammary gland, it spreads to various organs and tissues.

Cancer particles are carried in the bloodstream and reach the lymph nodes. This whole path is divided in medicine into 4, and in some sources 6 stages (including the 0th and 6th). In the process of identifying the stage of cancer, doctors take into account:

  • the size of the tumor itself;
  • defeat lymphatic system;
  • the presence of metastases;
  • spread of the disease to other organs.

To obtain this information, doctors use a number of diagnostic methods:

  1. Palpation. The presence of a neoplasm, its size, connection with surrounding tissues can be detected by the doctor already with palpation of the mammary gland.
  2. ultrasound. One of the most simple ways disease detection. This method is relatively inexpensive, simple, painless and fast, and therefore can be used in different ages.
  3. Mammography. Recommended for patients over the age of 40. It makes it possible to detect a tumor in situations where it is difficult to feel it with your hands, if there are increased accumulations of calcium in the chest (this may be evidence of stage 0 cancer). The result of a mammogram is an x-ray.
  4. MRI. Unlike mammography, this method does not involve the use of X-ray irradiation, and does not depend on the density of tissues in the mammary gland. Thus, MRI can be used at any period of the cycle and at any age. The method is called the most modern and highly informative. With its help, doctors not only learn about the size of the tumor, the features of its placement, but also receive other valuable information that will be used during the operation.
  5. Biopsy. Most often used after removal of the tumor. Provides a detailed study of the neoplasm under a microscope. Confirms or refutes the malignant nature of the neoplasm.

What are the early and late stages?

For the convenience of determining the treatment regimen, doctors often use the classification of breast cancer stages into:

The first ones are: 1, 2A, 2B, 3A. Late, respectively, are determined: 3B, 3C, 4 stages. The probability of complete recovery, the patient's life expectancy, the duration of treatment, the methods of therapy used, directly depend on the established stage. medical preparations etc.

Breast cancer stages 1-2 (that is, early stages) is treated quite successfully. In this case, the detected tumor is removed without resection of the mammary gland itself, that is, the woman manages to completely preserve the shape of the breast. Chemotherapy and radiation therapy in this case are not always used. The chance of recurrence after early treatment is very low.

Treatment in the later stages is complex. The breast is most often removed completely. The chance of relapse is very high. A woman should undergo systematic examinations by an oncologist.

According to medical practice, the ten-year survival rate after detection and treatment of stage 1 cancer is 98%.

Stage 2-3 breast cancer is distinguished by a ten-year patient survival of approximately 60 and 40%, respectively. At stage 4 of the disease, this figure is only 10%. So than used to be a woman consult a doctor and begin treatment of the disease, the greater the chance of overcoming the disease.

An annual medical examination using ultrasound and mammography in this case is a must for those who care about their health.

First and second stages of cancer

Stage 1 breast cancer is characterized by minor changes in the female body. The main features of this stage are:

  • small size of the neoplasm (from a few millimeters to 2 cm maximum);
  • absence of metastases;
  • there is no spread to nearby tissues.

Mammography at this stage will show the presence of a neoplasm, but it is difficult to detect its malignant nature. Therefore, a fine-needle biopsy is additionally performed. A particle of the tumor is taken for further careful examination under a microscope.

If cancer is still diagnosed, then the tumor must be carefully removed. In this case, as a rule, no more than 1 cm of healthy tissue is removed. After undergoing an additional course of chemotherapy (not always used), the patient can completely forget about the disease. Meanwhile, regular examinations by a mammologist are mandatory.

Stage 2 breast cancer is also early, but the disease already requires more complex treatment. There are two types (substages) of cancer of the 2nd degree:

  1. 2A. The tumor itself is not very large yet, but has a size of more than 2 cm. Cancer cells may already penetrate into the nearest lymph nodes. According to the American Cancer Society, if there is no lymphatic involvement in stage 2A, there is an 85% chance of complete recovery.
  2. 2b. Neoplasms are up to 5 cm in size, and the disease has been affecting several lymph nodes.
  3. It is possible to identify the disease at this stage using various diagnostic methods. Often a woman herself accidentally discovers a small seal in her chest. Information about the presence of stage 2 cancer can be obtained based on blood tests for tumor markers, CT, MRI, ultrasound and other methods.

If the lymph nodes are not affected, then at stage 2, a mastectomy is performed (complete removal of the mammary gland) or sectoral resection (the organ is preserved, but the tumor and surrounding healthy tissues are removed). In the case when the disease has already affected the lymph nodes, they also have to be removed. The most effective methods of treatment in this case, oncologists call chemotherapy and radiation therapy.

How to distinguish and treat the third stage?

Third-degree breast cancer is often referred to as a locally advanced variant of cancer. Most patients are diagnosed with the disease at this stage. If at stages 1-2 the disease develops slowly, then at 3 it becomes more aggressive. The main differences of the third stage can be called:

  • the presence of a large tumor (as a rule, its diameter is greater than 5 cm);
  • the formation extends deep into the tissues, the doctor can already confirm by palpation that the neoplasm goes beyond the breast;
  • the tumor damages the skin of the breast: it becomes flabby, may resemble a "lemon peel" or become covered with ulcers (stage 3B);
  • metastasis occurs to the closest lymph nodes (stage 3A). Perhaps the occurrence of micrometastases in other organs (although at this stage it is virtually impossible to identify them); if the neoplasm penetrates the chest, stage 3C is diagnosed.

In the third stage of breast cancer should be carried out complex therapy. If it is not carried out, the probability of a recurrence of the disease over the next 10 years is 100%. Only the removal of the tumor in this case is not enough.

Complete removal of the mammary gland, together with all micrometastases, shows a greater effectiveness of the treatment. Sometimes it is necessary to remove entire groups of lymph nodes.

The treatment regimen for the third stage is determined by the surgeon individually in each separate case. The most commonly used is:

  • preoperative therapy;
  • surgical treatment;
  • chemotherapy;
  • hormone therapy;
  • adjuvant treatment (radiation therapy).

In order for the treatment to be more effective, the patient must systematically take blood tests for the presence of tumor markers. If the indicators do not change or increase, the drugs are replaced by others.

Clinical manifestations of the fourth degree

4 degree of pathology refers to late. It differs:

  • the large size of the tumor neoplasm (as a rule, it occupies the entire mammary gland, grows into muscle tissue);
  • cancer cells spread to the bones of the skeleton, metastases enter the internal organs (first to the liver and lungs, and then to the adrenal glands, brain, skin);
  • close and distant lymph nodes are affected;
  • the tumor itself begins to disintegrate.

As for the external manifestations of late-stage cancer, we can name:

  • frequent headaches;
  • ache in the bones;
  • yellowness of the whole skin;
  • purulent, bleeding from the mammary gland;
  • an increase in the size of the breast itself;
  • sometimes redness, swelling and peeling of the breast;
  • severe pain in the chest.

Although one should not hope for a complete recovery at stage 4, however, oncologists say that treatment is a must. The main task of medicine is to remove pain prolong the life of the patient.

Surgery is ineffective in the advanced form of the disease, but it can be performed to reduce symptoms (most often during the period of tumor decay). If metastases have gone to the lungs and liver, and the tumor itself is small in size, it is advisable to carry out a combined surgical intervention.

Treatment is carried out with the help of complex therapy. Be sure the patient should use strong chemotherapy drugs, hormone therapy (if appropriate). In the case when a woman is sensitive to targeted therapy, she is also performed.

Radiation therapy is also an integral part of the treatment. It is especially effective in cases where metastases are single.

It becomes mandatory to use painkillers, which at least temporarily help to reduce the suffering of the patient.

Long-term treatment even at this stage gives about 10% of women a chance to continue life for more than 5 years.

Breast cancer is an aggressive disease. For a long time, it may not show any symptoms. With the progression of the pathology, the woman's chances for a long life are reduced. healthy life. A systematic examination by a mammologist or oncologist is the only way to protect yourself from late stages and death.

pro-rak.ru

Stages (degrees) of breast cancer

Breast tumors, unfortunately, are not always benign. AT modern world every 10 women hear a diagnosis of breast cancer. There are many reasons for the occurrence and development of breast cancer. A malignant neoplasm is so insidious and aggressive that it can affect both glands at the same time.

Breast cancer - causes:

  • being overweight is a major risk factor for developing malignant tumors chest;
  • smoking and overuse alcoholic drinks:
  • late menopause;
  • hormonal dependence;
  • genetic predisposition;
  • absence of children;
  • endocrine disorders;
  • nonspecific carcinogenic factors;
  • fibrocystic mastopathy.

Each patient has her own medical history. For example, cancers diagnosed in early stages are treated more successfully. If the disease is running, the results can be disastrous.

It's important to know! To minimize the risk of disease, oncologists recommend avoiding abortions. Against, frequent childbirth and long periods of breastfeeding reduce existing risk tumor development in the breast.

The reasons for having a breast exam are related to the appearance of the first signs of breast cancer at an early stage. Often, the manifestation of some symptoms gives a woman a reason to be wary and immediately consult a doctor.

Symptoms of breast cancer in stage 1 oncological process:

  • change in the contour, shape, reduction or increase in breast size;
  • discharge from the nipple for no apparent reason;
  • redness of the skin of the nipple or the entire mammary gland;
  • peeling of the skin;
  • the appearance of a seal;
  • swollen lymph nodes;
  • pain in the chest and axillary area;
  • increase in body temperature;
  • a sharp decrease in weight, loss of appetite, fatigue and general malaise are common symptoms breast cancer.

If you notice at least one of the symptoms, do not be careless. Diagnostics for breast cancer should be carried out regularly to detect oncology in the early stages of its development.

Breast cancer - classification by stage

Oncologists distinguish 4 main stages of breast cancer. Thanks to the classification, it is much easier for specialists to determine in what condition this moment the tumor is located, how intensively it progresses. Based on the results already obtained, any predictions should be made and a specific treatment should be selected. After all, the method of treating breast cancer depends precisely on what stage of development of the oncological disease is revealed. Medicine identifies 4 stages of breast cancer, including stage 0 or precancer stage.

In turn, stages 2 and 3 are divided into:

  • breast cancer stage 2 with substages A, B;
  • Stage 3 breast cancer with substages A, B, C.

stage 0 breast cancer

Stage zero breast cancer is, for the most part, a non-invasive cancer in which the tumor has not spread to nearby tissues.

It could be:

  • lobular adenocarcinoma of the breast. The term "lobular" means that the lesion concerns the lobules of the breast;
  • atypical ductal (ductal) hyperplasia;
  • atypical lobular (lobular) hyperplasia.

The presence of such precancerous conditions in women indicates that their body is predisposed to the development of breast cancer. Such patients should undergo more frequent medical examinations, as well as to do ultrasound and mammography of the mammary glands at least once a year.

stage 1 breast cancer

Oncological diseases in women are very common. In many cases, women suffer from breast cancer. There are several stages this disease. And although they say that it manifests itself at the last incurable stage, this is not always the case. The first stage of breast cancer also has its own symptoms.

Stage 1 breast cancer is an already invasive tumor or invasive breast cancer. The size of the tumor fluctuates within 2 cm. The process of spreading to nearby tissues has not begun. There are no metastases in the lymph nodes. If the disease is detected at stage 1, the treatment will be most effective, and the prognosis is positive.

How to detect breast cancer at stage 1?

One of the most quick methods diagnosis of breast cancer is: mammography. However, with the help this method no definitive diagnosis can be confirmed. For this, a special fine-needle biopsy and immunohistochemical study are performed. A biopsy is usually performed on the lymph nodes in order to exclude the possibility of damage to nearby tissues. An additional diagnostic method is MRI (magnetic resonance imaging).

It is worth noting! At the diagnostic stage, these patients are not shown a thorough radiological examination, including computed tomography of the lungs and liver, skeletal bone scintigraphy.

Treatment of breast cancer at stage 1

Thanks to professional diagnostics, oncologists have the opportunity to choose the most effective complex treatment. Taking into account the fact that stage 1 breast cancer is considered very early, and accordingly, the treatment will be more gentle than in the later stages of the development of the disease. At this stage in the development of breast oncology, a malignant tumor has just formed and has not yet had time to spread to the entire organ.

Stage 1 breast cancer treatment includes traditional methods therapy:

Surgical treatment of stage 1 breast cancer

Organ-preserving surgery in patients with stage 1 breast cancer is performed from the peri- or para-areolar approach after separation of the skin from the breast tissue using electrocoagulation. We allow access from the submammary fold or over the tumor. If there are signs of skin umbilization over the tumor and with invasive lobular carcinoma, it is indicated surgical treatment in volume not less than segmental resection. Stencinal biopsy and lamphadenectomy can be performed through a separate access to the armpit. Surgery can be combined with reduction mammoplasty or various types mastopexy. At the same time, it is permissible to perform a corrective operation on the contralateral mammary gland.

Types of organ-preserving resection within healthy tissues with a minimum volume of excision:

  • lumpectomy (sectoral resection) - the tumor is excised to the fascia with at least 1 cm of surrounding tissues;
  • tilectomy (segmental resection) - excision of the tumor with the skin above it to the fascia, with at least 1 cm of surrounding tissues;
  • quadrantectomy - excision of the tumor with removal of the skin above it, with the underlying fascia, within the unchanged surrounding tissues, usually more than 2 cm.
  • mastectomy is a surgical procedure in which the breast is completely removed, and the nearest lymph nodes are also removed.

It is worth noting! All types of organ-preserving operations are carried out with subsequent urgent cytological examination of smears from the bed of the removed sector and the sub-mammary space, as well as with a biopsy of the sentinal lymph nodes, followed by radiation therapy.

Radiation therapy for stage 1 breast cancer

Radiation therapy is given after complete healing postoperative wounds. It is aimed at reducing the incidence of recurrence and is indicated for all patients after organ-preserving surgery. Irradiation of the remaining part of the mammary gland ROD 1.8 – 2.5 Gy, SOD 50 Gy; 30 - 37 fractions (5 fractions per week). + Summing up an additional dose on the tumor bed (boost) 10 - 16 Gy. The duration of the course of radiation is 6 - 7 weeks (in the absence of a local radiation reaction).

Patients older than 70 years with hormone-dependent tumors and negative resection margins can refuse radiation therapy without compromising survival.

Chemotherapy for stage 2 breast cancer

Chemotherapy for breast cancer is prescribed if there is adverse factors forecast:

  • grade G2-3;
  • the presence of peritumoral vascular invasion;
  • lack of expression of estrogen receptors (ER) and progesterone (PgR), overexpression or amplification of HER-2/neu;
  • high level proliferation marker Ki-67 > 14% triple-negative basal-like breast cancer.
  • three drugs: 5-Fluorouracil + Methotrexate + Cyclophosphamide (Cyclophosphamide);
  • with relapses or metastases - 5-Fluorouracil + Doxorubicin hydrochloride + Cyclophosphamide;
  • with metastases - Taxol (Paclitaxel) + Vinblastine + Thiophosphamide + Doxorubicin.

The drugs are administered intravenously. The duration of chemotherapy is 4-6 cycles.

Hormone therapy in patients with stage I breast cancer with an expression of estrogen receptors (ER) and progesterone receptors (PgR) ≥ 3 points is carried out by prescribing tamoxifen (not taken simultaneously with antidepressants - selective inhibitors serotonin absorption) at 20 mg per day for 5 years.

If you are intolerant to tamoxifen and/or side effects aromatase inhibitors are used in combination with vitamin D, and calcium preparations for (ER+, PR±), (ER±, PR+) and (HER-2 expression 3+):

  • letrozole 2.5 mg per day;
  • anastrozole 1 mg per day;
  • exemestane 25 mg daily.

Stage 1 breast cancer: prognosis

Life expectancy in stage 1 breast cancer shows positive results, since the neoplasm is small in size and in almost 90% it is possible to remove the tumor surgically. After treating breast cancer at such an early stage of its development, a woman recovers quickly. The main thing is to be confident in your recovery and not lose strength of mind.

breast cancer stage 2

What to build on when determining the stage of breast cancer?

The classification of breast cancer by stages is based on:

  • tumor size;
  • the prevalence of the process and germination in the surrounding tissues;
  • the presence of metastases in regional (axillary, supraclavicular and subclavian) lymph nodes;
  • the presence of distant metastases of internal organs and tissues (liver, lungs, brain, bones of the skeleton and spine, etc.).

The diagnosis of cancer, of course, makes most women fall into despair and give up. After such news, I don’t want to do anything, just look for any miraculous remedies from different healers. Out of ignorance and despair, many women engage in “healing” fasting, which in no way has an optimistic effect on the course of the disease, leading the body into a state of weakening and exhaustion.

If we refer to statistics, then about 80% of women triumph over cancer, but only if it is detected at an early stage. Of course, simply identifying is not enough. It is very important that all breast cancer treatment is comprehensive and not interrupted.

What is stage 2 breast cancer and what is the prognosis?

Grade 2 breast cancer is considered an early stage of this type of disease. However, this is already a malignant tumor, the size of which reaches 5 cm. Also, in the second stage, the lymph nodes in the armpits are affected. The lesion is characterized by the fact that the lymph nodes do not have adhesions between themselves and other tissues. If there are adhesions, then this indicates inflammation, the focus of the tumor, which is caused by the spread of the tumor itself to other organs. The presence of adhesions is the first sign that breast cancer of the 2nd degree is moving into the 3rd.

Among all stages of cancer, only the second and third are divided into subspecies. This is necessary in order to distinguish between patients according to the volume of required surgical intervention, type of chemotherapy, and radiation treatment.

Signs and types of stage 2 breast cancer:

  • 2A substage. The size of the tumor exceeds 2 cm. The tumor spreads to the lymph nodes. If the tumor size is up to 5 cm, and the nodes are not affected, in 81% of cases this species ends with patients recovering. Such statistics are provided by the American Cancer Society;
  • 2B substage. It is characterized by a tumor diameter of 5 cm or more, with further spread to several nodes.

How to recognize the disease?

To begin with, in order to detect breast cancer, you must carefully monitor the condition of the breast, feel and examine it every day. If hardened nodules, seals or an uneven surface become noticeable, this should alert and become a reason for an immediate appeal to oncologists. Next, you should watch for any discharge from the nipple, sudden changes in the shape of the breast or the color of the nipple. The ideal option is to visit a doctor once a year for a diagnosis of the glands, an ultrasound and an examination by a mammologist.

Diagnosis of breast cancer 2nd degree

Tumors that are regarded as breast cancer of the 2nd degree have quite vivid symptoms, which makes it possible to determine the disease quite simply. All that is required is sufficient attention to your body and to the changes that occur in it.

Palpation and examination of the mammary glands is a simple diagnostic procedure, during which nodules are found in the thickness of the mammary gland, which in turn becomes the main reason for women to visit a doctor. That is why breast cancer of the 2nd degree, most often, occurs during the initial diagnosis.

In the second stage, cancerous tumors can reach enough large sizes, therefore, they can be diagnosed without the use of additional research methods.

Detailed diagnosis is carried out using the following methods:

  • Ultrasound for patients under 40;
  • mammography of the older generation of women;
  • MRI to determine the presence of metastases;
  • tumor markers for breast cancer;
  • biopsy followed by histological examination of the material;
  • a study of the lymph nodes is performed as an additional examination for the presence of metastases;
  • scintigraphy;
  • CT abdominal cavity;
  • general analyzes blood and urine.

It's important to know! A histological examination of a suspicious area is performed in order to determine the nature of the tumor, namely, whether stage 2 breast cancer is confirmed, or whether the tumor is at a different stage of development.

Stage 2 Breast Cancer Treatment

Depending on the size of the tumor, a course of chemotherapy therapy may be prescribed, both before and after surgery.

It is worth noting! Treatment for stage 2 breast cancer is similar to treatment for stage 1 breast cancer.

To achieve positive results of treatment, you can use the following therapies:

Breast cancer grade 2: treatment involves radical operation, the volume of which can only be determined by the attending physician. This can be either a mastectomy or an organ-preserving type of operation (sectoral resection, quadrantectomy of the mammary gland). If the lymph nodes are affected, they are also removed surgically.

Cancer cells are destroyed by powerful modern drugs. Chemotherapy is used to treat any type of cancer. Therapeutic regimens and the duration of the course may differ depending on the individual characteristics cancer.

This type of therapy does not always take place. It is used in combination with surgical treatment or is part of a comprehensive treatment program.

Life expectancy for stage 2 breast cancer

Breast cancer in the second stage is a relatively favorable form of the disease, despite the fact that it belongs to the group of malignant tumors, more than 80% of patients overcome the 5-year survival limit. After this period, patients are not monitored, since it is believed that the disease can no longer recur. Breast cancer of the 2nd degree with the right treatment is characterized by a favorable outcome and the survival rate is 80-85%.

breast cancer stage 3

Very often, oncologists refer inflammatory breast cancer to grade 3 and position it as one of the most serious forms of the disease, occurring in 10% of patients. It is manifested, first of all, by reddening of the skin on the chest. It is usually warm and often covered orange peel or pimples. Induration may also be observed, but do not confuse the usual induration with mastitis with inflammatory cancer. Very often, not a simple seal is formed, but a clear knot. This indicates the spread of "other" cells to the tissues, which leads to their soldering. Such a tumor has no contour and is often accompanied by a change in the shape of the breast.

Stage 3 breast cancer is more serious and dangerous to a woman's life and health. It also has three substages: 3A, 3B, 3C. The third stage can be characterized by the active movement of cells to the nearest tissue areas. The main symptoms of the disease begin to appear. In addition to seals in the areas of the chest and axillary fossa, transparent or bloody discharge may begin, there is a complete deformation of the chest and a change in the structure and color of the skin.

The third stage can be conditionally divided into types:

  • 3A substage. The tumor can be larger or smaller than 5 cm. In the first case, the tumor begins to spread to the lymph nodes in the chest. The second option is about the same, only on the side of the cancerous process itself;
  • 3B substage. The tumor has already reached the walls chest or touched the skin. In this case, the cancer has spread to the lymph, as well as to the nodes in the sternum. Inflammatory cancer can also be attributed to this stage, when the breast turns red and swells;
  • 3C substage. The tumor can be of any size. The disease rapidly metastasizes to all groups of lymph nodes (axillary, supraclavicular, neck).



The main treatment for stage 3 breast cancer is a complex attack on the tumor, which includes chemotherapy and hormone therapy. And only after the medical measures a decision is made to proceed with surgery. With a positive result of the surgeons, the healing process a course of chemotherapy or targeted ionized radiation.

However, with tumor necrosis, bleeding or abscess formation, treatment begins with surgery (palliative radical mastectomy). And later, after the operation, chemotherapy and radiation therapy are used.

Chemotherapy is carried out with the help of cytotoxic drugs that destroy the mechanism of division of cancer cells and thereby destroy them.

These drugs include:

  • platinum preparations (Cytoplastin, Cisplatin, Carboplatin, Triplatin, etc.);
  • preparations of the taxon group (Paclitaxel, Taxane, Paclitax, Paxen, etc.);
  • drugs of the group of vinca alkaloids (Vincristine, Vinorelbine, Vinblastine, Maverex);
  • oxazaphosphorin derivatives (Endoxan, Mafosfamide, Trofosfamide, etc.);
  • fluoropyrimidine carbamate derivatives (Capecitabine, Xeloda), etc.

Chemotherapy for breast cancer can be used as the only treatment, as well as to reduce the size of the tumor before surgical removal and stop the formation of metastases after surgery.

Surgical intervention consists in removing the tumor and part of the tissues surrounding it (lumpectomy). Mastectomy - performed in most clinical cases of breast cancer - removal of the entire mammary gland.

Radiation therapy for breast cancer, like other therapies, destroys cancer cells under the influence of radioactive irradiation. Radiation therapy can complement chemotherapy and surgical removal of a breast tumor.

Hormone therapy is carried out for patients only with hormone-dependent neoplasms, that is, in the presence of estrogen and progesterone receptors in cancer cells. Assign drugs to the group of aromatase inhibitors, which include Anastrozole, Letrozole or Exemestane.

Combined treatment of stages of breast cancer involves individual selection and simultaneous or alternate use of all methods of therapy.

Life expectancy for stage 3 breast cancer

Already at the 3rd stage, cancer is considered incurable. However, it is quite realistic to extend life for more than one dozen years, especially if this is only the initial 3rd degree of development.

It has already been mentioned that at the third stage, cells begin to actively divide and capture the free space of neighboring tissues. The statistics of stage 3 breast cancer suggests that the prognosis for successful treatment can be observed only in 30% of patients. However, it is too early to be afraid. If you properly organize the treatment and follow the recommendations of the oncologist, you can defeat cancer.

breast cancer stage 4

The biggest problem in oncology is running stage oncological process, that is, 3 or 4 degree. The presence of such forms of neoplasms is alarming, since modern conditions diagnostics are set at a fairly high level. This is explained by the fact that most patients neglect their health and do not react carefully enough to the presence of signs of the disease.

Stage 4 breast cancer is usually incurable. This is due to the development of the oncological process not only within the mammary glands, the axillary region, nodes and main organs, including the brain, are also affected. Cancer cells (metastases) spread throughout the body and invade the lungs, liver, bones, and other organs. Without a doubt, stage 4 cancer is the most severe form of breast cancer.

What is this cancer and what is the chance of survival?

What is meant by stage 4 breast cancer?

  1. The presence of cancer in one or both mammary glands. The tumor is able to germinate throughout the entire thickness of the mammary gland and go beyond it. The neoplasm reaches a very large size and spreads to: bones, muscles, intrathoracic lymph nodes and lymphatic collectors of the axillary region.
  2. A tumor of any size with distant metastases in the internal organs.
  3. Breast cancer is accompanied by the disintegration of the neoplasm.

Reasons for late diagnosis of breast cancer:

  • late appeal for medical care;
  • advanced age (60-80 years;
  • rapid and rapid progression of cancer;
  • cancer recurrence and disease progression after radical treatment. This part of stage 4 cancers has a significant place in the overall structure of advanced breast cancers. Most often this is possible in the treatment of women with stage 3 cancer, when the tumor has spread beyond the breast or has given large metastases to the axillary lymph nodes.

Diagnosis of stage 4 breast cancer is not difficult. You do not need to be a great specialist to identify an obvious tumor in the mammary gland or in the axillary region, which is carried out by enlarged lymph nodes. At this stage of development of oncology of the mammary glands, symptoms such as:

  • change in the shape of the breast;
  • resizing (enlargement or reduction of the breast);
  • purulent and bloody issues from the nipple bad smell;
  • redness, peeling of the chest;
  • severe pain;
  • yellowness of the skin with metastatic liver damage;
  • headaches, bone pain.

Treatment of metastatic breast cancer stage 4

Unfortunately, at this stage, it is difficult to fight breast cancer, and this struggle does not give positive results, since at stage 4, it is possible to talk only about prolonging life and facilitating it.

There are many types and types of breast cancer, and each differs in its degree of aggressiveness and spread of cancer cells. Some rapidly give metastases, while others, being at stage 4, have single metastases. The effectiveness of the treatment depends on this. It is necessary to treat metastatic breast cancer comprehensively.

The main method of treatment of such a neglected disease remains combined drug therapy, which should include the use of powerful chemotherapy drugs, if necessary, hormone therapy, targeted therapy drugs (of course, only in people who are sensitive to such treatment).

If the tumor is not large and there are single metastases in the lungs and liver, it is possible to perform a combined surgical intervention, after which it is necessary to conduct a course of chemotherapy, hormone therapy and radiation therapy, if necessary. The operation is performed to remove one or both mammary glands, as well as resection of the segments of the liver or lungs affected by metastases.

Also, surgery to remove the mammary gland is performed to alleviate the symptoms that are caused by the decay of the neoplasm. Before and after surgery, courses of chemotherapy and radiation therapy are prescribed.

There are patients who are not suitable for surgery. They are given pain medications to help reduce pain and improve well-being.

Breast cancer stage 4, what is the prognosis and life expectancy?

It is worth noting that the survival prognosis for stage 4 breast cancer is quite modest. And if at initial stages development of a malignant neoplasm of the breast, the 5th survival rate is about 85% or even 90% of patients, then with the 4th degree of damage to the female body, with a diagnosis of breast cancer, the percentage of five-year survival is negligible and is no more than 10%.

In any case, even with such a terrible diagnosis, sitting with folded arms is not a way out. Many women at this stage of the disease, with the help of chemotherapy and hormone therapy, managed to prolong their lives for many years. The main thing is not to give up!

Video on the topic: Breast cancer: stages, signs and symptoms, treatment

Be healthy!

onkolog-24.ru

Stages of breast cancer

Treatment of the stages of breast cancer depends on the results of the examination of the patient and her state of health and should take into account all the factors in the development of pathology. To date, in oncology of the mammary glands, such treatment methods are used as:

  • chemotherapy;
  • surgical removal of the tumor;
  • radiation therapy (radiotherapy);
  • hormone therapy;
  • targeted (targeted) therapy;
  • combination therapy.

Chemotherapy is carried out with the help of cytotoxic (cytostatic) drugs that disrupt the mechanism of division of pathological cells and thereby lead to the cessation of their proliferation. These drugs include: platinum preparations (Cytoplastin, Cisplatin, Carboplatin, Triplatin, etc.); preparations of the taxon group (Paclitaxel, Taxane, Paclitax, Paxen, etc.); drugs of the group of vinca alkaloids (Vincristine Vinorelbine, Vinblastine, Maverex); oxazaphosphorin derivatives (Endoxan, Mafosfamide, Trofosfamide, etc.); fluoropyrimidine carbamate derivatives (Capecitabine, Xeloda), etc.

In this case, breast cancer chemotherapy can be carried out as the only method of treatment, as well as in order to reduce the size of the tumor before its surgical removal and stop the formation of metastases after surgery.

Surgical intervention - removal of the tumor and part of the surrounding tissues (lumpectomy) or removal of the entire breast (mastectomy) - is performed in most clinical cases of breast cancer, especially if early stages of breast cancer are diagnosed.

Radiation therapy for breast cancer, as in the case of tumors of other localization, is designed to cause mutation and death of cancer cells under the influence of radioactive irradiation. Radiation therapy can complement chemotherapy and surgical removal of a breast tumor.

According to experts, hormonal therapy of breast tumors is advisable to be carried out after their removal only for patients with hormone-dependent neoplasms, that is, if cancer cells have estrogen and progesterone receptors. In this case, drugs of the group of aromatase inhibitors (cytochrome P450-dependent enzyme) are prescribed - Anastrozole, Letrozole or Exemestane.

Targeted therapy targeting a tumor and its metastases is based on the ability of recombinant monoclonal antibodies IgG1 class (similar to those produced immune cells human) selectively bind to HER2/neu molecular receptors on the outer shell of cancer cells and stop their growth. Among the most widely used drugs in this group, oncologists name trastuzumab and epratuzumab.

Combined treatment of breast cancer stages involves individual selection and simultaneous or alternate use of all the methods listed above.

Treatment for Stage 0 Breast Cancer

In the treatment of stage 0 breast cancer, the removal of the pathological sector of the mammary gland (sectoral resection) or lumpectomy (see above) is used. These operations may be accompanied by lymph node dissection - the removal of nearby lymph nodes.

In addition, a course of radiation therapy is mandatory, and in case of increased tumor expression of HER2, targeted therapy using recombinant monoclonal antibodies.

Treatment of stage 1 breast cancer

In the treatment of stage 1 breast cancer, a lumpectomy is performed with the removal of the axillary lymph node. To eliminate the remaining cells of the tumor and avoid its recurrence, after surgical intervention adjuvant (postoperative) radiation, hormonal or chemotherapy is prescribed. And in the case of tumor overexpression of HER2, adjuvant targeted therapy should be used.

Treatment for stage 2 breast cancer

The obligatory stage of treatment of stage 2 breast cancer is the partial removal of the tissues of the affected organ (lumpectomy) or the complete removal of the gland (mastectomy), which depends on the individual. clinical picture diseases. In this case, the affected regional lymph nodes are also subject to removal. Patients with tumors larger than 5 cm undergo chemotherapy twice: before and after surgery.

According to the indications, postoperative courses of radiation or hormonal therapy are carried out.

In the case of a mastectomy, an endoprosthesis is performed over time. Plastic surgery chest.

Treatment for stage 3 breast cancer

The beginning of the treatment of stage 3 breast cancer is a complex attack on cancer cells with the help of cytotoxic drugs (chemotherapy) and oncological hormone therapy. And only after positive results, a decision is made to carry out the operation. A positive result of surgeons is fixed by a second course of chemotherapy or targeted ionized radiation.

However, with tumor necrosis, bleeding or abscess formation, treatment begins with surgery (palliative radical mastectomy). And after that, chemotherapy and radiation therapy is applied.

In hormone-dependent neoplasms, it is indicated long-term use aromatase inhibitors (hormone therapy), and in case of tumor overexpression of HER2 receptors (for more details, see Diagnosis of breast cancer), the use of monoclonal antibodies.

Treatment for stage 4 breast cancer

According to oncologists, the treatment of stage 4 breast cancer - a recurrent and metastatic tumor process - in most cases is palliative, that is, it is aimed at alleviating the condition of patients. However, full-fledged complex therapy at this stage of the disease can prolong life.

First of all, in order to reduce the level of intoxication of the body, a sanitation mastectomy is necessary, which consists in the most complete removal of necrotic and ulcerated tissues. And to fight metastases, the whole arsenal of anticancer methods is used: complex chemotherapy, radiation and hormone therapy.

Besides, in without fail there should be supportive treatment of concomitant pathological processes. So, with anemia and thrombocytopenia, taking appropriate medications and blood transfusions are indicated; with bone metastases - the appointment of drugs from the bisphosphonate group, etc.

The development of the disease goes through several stages, and the stages of breast cancer are clearly defined. Therefore, it is necessary to seek medical help in time and prevent stages that cannot be treated. oncological diseases.

ilive.com.ua

Classification of stages of breast cancer

  • 14-02-2016
  • 2150 Views
  • 35 Rating
  • Stages of breast cancer
  • Recurrent breast cancer

Breast cancer is the leader among all diagnosed cancers in women. The stages of breast cancer are different, so if you suspect the presence of a malignant neoplasm, you should not despair prematurely, because with timely treatment there is a high chance of recovery.

Methods for determining the stage of breast cancer

Primary diagnosis of breast cancer occurs by examining the main symptoms and performing mammography and ultrasound. The presence of the disease is evidenced by the compaction of the mammary gland and a change in its shape, a feeling of discomfort and an increase in the lymph nodes in the armpits. Even if these symptoms are absent, mammography and ultrasound can show the presence of a neoplasm. To confirm the diagnosis, a biopsy is additionally prescribed - taking the tumor tissue with a special needle and sending the resulting fragment to laboratory analysis.

The second step after diagnosing cancer is determining its stage. The following methods are used for this:

  • computed tomography of the abdomen and chest;
  • magnetic resonance imaging of the abdomen and chest cavity, small pelvis;
  • chest x-ray;
  • skeletal scan.

Computed tomography can determine if the tumor has spread to other organs. CT scans take detailed pictures of the abdomen and chest using a computer-connected X-ray machine. Bone scanning in patients with breast cancer is performed to determine the extent to which the tumor process has spread to the bones.

Every year, the methods of molecular genetic research are being used more and more actively. In the course of such a study, the genes of tumor cells, their sensitivity to chemotherapy drugs and hormones are studied. The data obtained helps doctors in choosing the most suitable for a particular patient. medicines, which increases the likelihood that the treatment will be successful.

Breast cancer is a formidable disease in which malignant degeneration of tissues occurs. In the early stages, a woman may not feel obvious symptoms. The tumor can grow rapidly and spread to other organs. It is important to notice the formation of seals in time. If even slight changes in the shape of the breast, discharge from the nipple, burning or pulling pain localized in one of the areas of the mammary gland are found, then it is necessary to undergo an examination, establish the nature of the pathology, and determine at what stage of development the process is.

Content:

Stages of cancer and their signs

Breast cancer is staged based on factors such as the size of the tumor, changes in the lymph nodes, and spread to other tissues and organs. Depending on how far pathological cells have penetrated into organs and tissues, invasive and non-invasive types of cancer are distinguished.

Non-invasive. The abnormal cells do not come out of the milk ducts (ductal carcinoma) or milk lobules (lobular carcinoma). Many doctors consider this type of disease only a precancerous condition. Non-invasive cancer is called stage zero. It is usually 98% treatable.

Invasive. It spreads to the lymphatic system, skin, chest bones, various organs. Depending on where the cells are found, as well as the size of the neoplasm, invasive cancer is divided into 4 stages. The possibility of cure and the percentage of survival of patients depend on the stage of development of the pathology.

First stage

Pathological cells extend beyond the milk ducts and lobules, but remain in the mammary gland. The diameter of the neoplasm does not exceed 2 cm. In 70-95% of cases, the patient can live 5 years after the detection of cancer.

Second stage

The tumor grows, affects the lymph nodes in the armpits. There are 2 variants of its development.

2A. This stage includes tumors with a diameter of no more than 2 cm, affecting the axillary lymph nodes, or tumors with a diameter of more than 5 cm, but not affecting the lymph nodes.

2b. The size of the tumor is from 2 to 5 cm. The nodes under the armpits are slightly affected.

The 5-year survival rate for stage 2 cancer is 50-80%.

Third stage

Tumor cells are found in the axillary nodes. At the same time, they can be soldered to each other, as well as to the skin of the mammary gland. In addition, pathological cells enter the nodes behind the sternum. There are the following options for this stage of development of breast cancer:

3A. These include tumors with the following features:

  • diameter is not more than 5 cm, cancer cells are found in the armpit (lymph nodes fuse with each other and with surrounding tissues, forming a conglomerate), in the sternum;
  • the diameter is more than 5 cm, the tumor affects the axillary nodes (single or fused from several), the retrosternal lymph nodes are also involved in the tumor process.

3b. The tumor can be of any size, but it is characteristic that it necessarily captures the bones of the chest and the skin of the breast. The gland swells, changes appearance skin surface (separate nodules appear). Options may be as follows:

  • affecting the sternum and skin, pathological cells also penetrate into the lymph nodes under the arms;
  • the tumor affects the soldered axillary nodes, as well as nodes in the sternum;
  • cancer cells cover lymphatic vessels glands located in the skin, due to which it turns red and swells (this is the so-called inflammatory cancer).

3C. Regardless of size, the tumor can cover not only the lymph nodes under the armpits and behind the sternum, but also in the collarbone area. The five-year survival rate for patients with stage 3 cancer is 10-50%.

Fourth stage

Patient survival is approximately 10%. At this stage of breast cancer, tumor cells are found not only in the mammary glands, but also in peripheral areas (eg, bones, liver, lungs). At the same time, cancerous cells of breast tissues appear in the organ affected by metastases, and not the organ itself. This is taken into account when choosing a method of treatment.

Addition: Even if treatment is carried out, the spread cancerous tumor stopped, undetected cancer cells may remain in the body. Therefore, a relapse is possible. And recurrence after breast treatment, it can touch a completely different organ (for example, the lungs or brain).

"Early" and "late" stages of cancer

The "early" include zero, first and second (if the tumor spreads to less than 3 nodes) stages of breast cancer. The "later" include the second (if the number of affected nodes is more than 3) and the third stage. The fourth stage is considered "late".

Metastases most often appear in the lungs and liver. Less commonly, they occur on the skin, in the adrenal glands, in the brain.

Video: Signs of breast cancer

Diagnostics

When breast cancer is suspected, examination is carried out using various methods.

Visual inspection and palpation. Detection of seals, characteristic changes in the breast.

Mammography and ultrasound. Confirmation of the presence of a tumor, determining its location, size.

Ductography. The study of the patency of the milk ducts.

Biopsy of affected tissues. Histological examination to detect malignant cells. Then the stage of breast cancer is determined.

Bone scan. Allows you to detect bone damage by introducing a radioactive substance into them through the blood.

Biopsy of lymph nodes. Often it is possible to establish the stage of the tumor process only after the removal of one of the lymph nodes (the so-called sentinel node). Usually, when the lymphatic system is affected, cancer cells first appear in 1 node, and then spread further. The sentinel node can be identified by injecting a dye or radioactive substance directly next to the tumor.

CT scan. The method allows to detect metastases in the lungs, liver. CT with intravenous administration of a contrast agent makes it possible to more accurately identify the nature of the lesion.

MRI. With this method, you can monitor the development of the tumor or its condition during treatment.

Video: Diagnosis of breast cancer


Cellulite has several stages. Starting the fight against cellulite, it is very important to study the features of its development and conduct a diagnosis. After all, to combat cellulite on different stages various measures are needed.

Having well studied the external signs of cellulite at different stages and having understood what happens at the same time at the cellular level, it is possible to carry out the primary cellulite diagnosis at home. By determining the stage of cellulite, you can realistically assess the scale of the problem and select the most effective set of measures to combat the "orange peel".

2 scale stages of cellulite

There are several classifications of cellulite stages, containing from 3 to 8 steps. In this article, we will present the most common 4-step classification with which you can diagnose cellulite at home.

How to determine the stage of cellulite yourself

Stand in front of a mirror. Feel and carefully inspect problem areas. Based external signs, you will be able to determine the stage of cellulite and understand what is happening in the tissues.

Stage 0 and the first signs of cellulite

Zero stage corresponds to healthy state connective tissue. If during the examination you did not find any loss of tone, lethargy and discoloration of the skin, and when you squeeze it with your hand, tuberosity did not appear, then you can safely be congratulated. You don't have a trace of cellulite.

First alarm

If you notice an increase in the volume of the hips and buttocks, a loss of skin tone - this may be the first signal of the appearance of cellulite.

An increase in the volume of problem areas and loss of skin tone can be caused by metabolic disorders and the formation of edema of the subcutaneous fat. The supply of oxygen necessary for cells is difficult. There are serious metabolic changes that contribute to the appearance of an orange peel.

1st stage of cellulite

Externally, the first stage of cellulite is very weak. On examination, there is a loss of skin elasticity in the area of ​​the thighs and buttocks. If you squeeze the skin on the thighs, they become visible characteristics cellulite: the skin is very dense, its bumpy structure is clearly visible.

In the changed connective tissue there is not enough oxygen. Toxic decay products accumulate there, the volume of liquid increases. To isolate foreign substances, the connective tissue grows, forming a dense jelly-like substance. The original structure of fat cells changes.

Fight against cellulite of the first stage

  • The most basic method of fighting at the first stage of cellulite and at the first signs of its manifestation is the restoration of disturbed metabolism. This can be achieved with the help of special diets.
  • It is also necessary to ensure the outflow of excess fluid from the tissues, which will relieve swelling and normalize cell nutrition. This will help visit saunas, baths, holding hot wraps.
  • Achieving sustainable positive result can be accelerated with the help of daily anti-cellulite self-massage, the use of anti-cellulite cosmetics and physical exercise.

Second stage of cellulite

In the second stage of cellulite, it is possible to distinguish seals and tubercles on the skin, formed by excess fluid and fatty deposits, without squeezing. The leather feels like rubber to the touch. When squeezed, pain is added.

Deposits of fluid and fat in the subcutaneous fat are locked in the subcutaneous layers, as the vessels are compressed.

Connective tissue fibers envelop more or less large accumulations of fat, forming more and more skin irregularities. This can lead to loss of sensation in the affected areas.

Fighting methods

In order to destroy these seals, normalize the circulation of fluid in the subcutaneous layers, a complex intensive method of struggle is needed: diet, physical exercise, anti-cellulite massage, the use of anti-cellulite cosmetics, wraps, a bath with a broom, etc. In addition, it is worth using non-radical salon methods. Suitable, for example, hardware massage.

The third stage of cellulite

In the third stage of cellulite, the surface of the skin looks rough, uneven. The skin is swollen, all in seals, often bluish in color. The skin is very thick and cold to the touch. You can observe loss of skin sensitivity. There may be such figure defects as "riding breeches" on the hips, sagging buttocks.

The appearance and atrophy of muscle tissues indicate a serious violation of blood supply, damage to nerve endings and a disorder of metabolic processes in the affected areas. Fat deposits disrupt blood circulation, infringe on nerve endings. Because of this, the skin loses its sensitivity. As a result of the limiting growth of the connective tissue, the affected areas are dehydrated and become practically lifeless. The subcutaneous fat is destroyed. At this stage, there is a risk of inflammatory processes in tissues.

Fighting methods

The third stage of cellulite - serious problem. To cope with such cellulite, it is necessary to destroy the deposits and restore the normal metabolism in the skin. That is, in addition to diet, lymphatic drainage procedures and the use of anti-cellulite cosmetics, additional exposure will be required.

Traditionally, power massage has been used to break down fatty deposits. However, when exposed to connective tissue, there was a risk of damaging the nerve endings.

Currently the safest and effective means the following salon procedures are considered to break cellulite deposits:

  • electrolipolysis;
  • lipopolysis;
  • ultrasound.

If, after the examination, you have identified the first or second stage of cellulite, or the first signs of its manifestation, you can deal with this problem at home. See section "Treatment of cellulite at home" . With the 2nd and 3rd stages of cellulite, it is advisable to seek help from a cosmetologist. But home methods to combat cellulite will be an excellent assistant to salon procedures.

A beautician will help you spend more accurate diagnosis cellulite. One of the diagnostic procedures in a beauty salon is a biopsy. This is a painless taking of a piece of tissue from the affected area for microscopic examination.