Syphilis pills are medicines for oral administration. This infectious disease is caused by pale treponema, which affects the mucous membranes, skin and organs. Infection occurs through microtrauma or during intrauterine development. Syphilis proceeds in 4 stages, each of which has its own treatment regimens. It will take a long time to take the pills. They are prescribed immediately after confirmation of the diagnosis.
Currently, there are various drugs for the treatment of syphilis, which give results at any stage. First of all, these are antibiotics and iodine compounds. In the past, the tablets contained mercury, to which treponema is sensitive. Currently, such anti-syphilis drugs are prohibited for use due to their high toxicity.
Is oral medication effective?
Treatment of syphilis with pills is carried out at any time of the disease. However, full recovery is possible only with its primary and secondary form. Oral administration of drugs is switched over when destructive changes in muscle tissues appear after frequent injections. However, the pills have side effects from the digestive system. With prolonged use, it is possible to develop ulcers, liver damage.
Penicillin antibiotics form the basis of drug treatment for syphilis. Pale treponema did not develop resistance to them. In the form of tablets, auxiliary medicines are also used - immunostimulants, vitamins. In certain cases, the same drug is taken orally before an intramuscular injection.
Long-acting antibiotics can be used to treat syphilis on an outpatient basis. These effective drugs quickly eradicate treponema pale, but can have side effects. In the presence of allergic reactions to penicillin, antibacterial agents of other pharmacological groups are used:
- tetracyclines;
- cephalosporins;
- macrolides;
- streptomycins;
- aminoglycosides.
Primary syphilis is easy to treat. In this case, the tablets are taken for 3 months, after which complete recovery occurs. With advanced forms, the therapeutic course can last more than 2 years. By the time syphilis passes into the tertiary period, the causative agent of the infection develops resistance to antibiotics. In this case, arsenic and bismuth preparations are used.
A patient is considered healthy if there are no symptoms of syphilis and tests give a negative result within 5 years after the end of taking the pills.
How do medications work?
The mechanism of action of such drugs depends on the substances that make up them. Penicillin prevents the formation of the cell membrane of treponema pallidum. Betalactam substance reacts with bacterial proteins. This promotes the activation of enzymes that contribute to the self-destruction of the bacteria.
Penicillin is not destroyed by gastric juice. The maximum concentration in the blood is achieved 2 hours after taking the pill. The medicine for syphilis gradually spreads to all tissues and biological environments of the body. Its concentration in the blood gradually decreases. Part of the active substance is excreted by the kidneys unchanged within 6 hours after ingestion. The elimination period is extended in the presence of diseases of the excretory system.
Types of pills
There are many medicines that can cure syphilis. By combining drugs of various pharmacological groups, the doctor draws up the most effective schemes for eliminating sexually transmitted diseases:
Application rules
Modern methods of treating syphilis involve an individual selection of drugs. This takes into account the stage of infection, the patient's age and the presence of concomitant pathologies.
The tablets should be taken every 8 hours half an hour before meals. The duration of treatment depends on the severity of the symptoms of the disease and the results of its use in the first days. During the period of treatment, it is necessary to refrain from drinking alcohol and smoking. Do not exceed the dosage prescribed by your doctor.
Treatment regimens for secondary and tertiary syphilis include drugs from several pharmacological groups. This increases the effectiveness of therapy and speeds up the healing process. In this case, it is necessary to take into account the compatibility of drugs. Penicillins, which are effective against proliferating bacteria, cannot be used in combination with bacteriostatics (aminoglycosides).
When interacting with anti-inflammatory and antirheumatic drugs, antibiotics may be cleared from the body more slowly. Most of them reduce the effectiveness of combined oral contraceptives. Intravenous administration of glucose while taking penicillin can provoke the development of allergic reactions.
Syphilis injections are used when antibacterial tablets are ineffective. When injected, the maximum concentration of the active substance in the blood and its penetration into the foci of infection are ensured. This makes therapy more effective and faster recovery. Modern treatment regimens for syphilis include antibacterial agents, as well as bismuth and arsenic preparations.
Antibiotic groups
After receiving a positive test result, the patient must prepare for long-term treatment, especially if the disease has turned into an advanced form. In this case, the drugs will have to be used for at least 2 years. Early antibiotic therapy lasts about 12 months. An experienced doctor knows which injections are used for primary and secondary syphilis. The basis of the therapeutic course is made up of the most effective antibiotics of the penicillin series.
In the presence of individual intolerance, drugs of other pharmacological groups are prescribed:
- macrolides;
- fluoroquinolones;
- tetracyclines.
Ceftriaxone is used to eliminate syphilitic infection in children and pregnant women. Erythromycin is no less effective and safe. There are no serious side effects when using them. All drugs should be selected by the attending physician, self-medication can contribute to the development of dangerous complications.
Is quick treatment possible?
Not everyone knows the infection is fast. Nowadays, there are more and more ads that offer one-shot syphilis treatment. However, such therapy is not only ineffective, but also dangerous.
It is not known how the introduction of unknown drugs will affect the state of health. In addition, the patient, hoping for a speedy recovery, does not take tests and does not visit a doctor. Meanwhile, pale treponema continues to actively multiply and affect organs.
The course of traditional treatment for syphilis lasts 10-40 days. Depending on the chosen scheme, the type of antibiotic and the dosage, injections are given up to 160 times. Therefore, injections must be given in a specialized department of the hospital. Currently, the possibility of anonymous therapy is provided.
List of drugs
What are the names of syphilis injections you should know?
The most common treatment for the disease is penicillin. This is the most effective drug against treponema. After entering the bloodstream, it begins to act quickly, but has a short-lived effect. Injections must be given every 3 hours for 2 weeks.
The modified analogue of penicillin is Bicillin, which differs from the predecessor in the composition and concentration of the active substance. The treatment regimen with this drug allows you to choose the number of injections and the frequency of their setting:
- Bicillin-3 is administered 2 times a day.
- Bicillin-1 - once a day.
- Bicillin-5 is used for outpatient treatment of syphilis, injections are given once a week.
Ceftriaxone is less effective than penicillin. However, with its help, therapy can be carried out. The injection is given once a day.
Intramuscular injections of Doxycycline are given 2 times a day. During the period of administration of this drug, it is recommended to refuse prolonged exposure to the sun, since the antibiotic increases the sensitivity of the skin. It is not recommended to prescribe Doxycycline to children, as it disrupts the processes of bone formation.
Tetracycline is administered 2 times a day. Contraindications to its use are renal and hepatic failure, childhood.
How are syphilis injections given?
An intramuscular injection is placed in the upper outer quadrant of the buttock. Intravenous administration is rarely practiced. To ensure the possibility of normal distribution of the drug, it is necessary not only to choose the correct injection site, but also to determine the thickness of the subcutaneous tissue. The needle should enter the muscle tissue where the rate of absorption of the solution is maximum. With the correct formulation of the injection, strong pain should not occur. In some cases, the standard length of the 7 cm needle is not enough, which is why extended ones are used.
When injecting the drug intramuscularly, do not collect the skin, it is better to press it with two fingers. The needle is quickly inserted perpendicular to the muscle. If after that there is blood in the cavity of the syringe, the injection was made into the vessel. Such administration of drugs for syphilis is not recommended due to the negative effect on tissues. The needle must be removed and injected again. If blood does not appear, it is necessary to slowly press on the plunger and inject the solution into the muscle. For each subsequent injection, a new area of the buttocks should be selected. The patient should be as relaxed as possible.
Antibacterial drugs can cause mild inflammation of the muscle tissue. Scarring, necrosis, edema, or tissue infiltration may occur at the injection site.
Repeated injections cause severe pain and help replace muscle tissue with connective tissue. Antibiotic injections are recommended to be given in the left and right buttocks in turn. Before removing the needle, the patient's skin is pressed. This helps to reduce the intensity of pain and the normal distribution of the drug.
After the first injections, an increase in temperature may be observed. This is due to the poisoning of the body with the decay products of treponema. You should not refuse further therapy after the onset of this symptom.
This is a disease that occurs due to the action of the bacteria "treponema pale". It affects the internal organs, mucous membranes, the musculoskeletal and nervous systems. The route of infection is microcracks, injured skin and the birth process.
Can syphilis be cured with pills? Syphilis pills are an effective pharmaceutical agent aimed at combating the disease. The treatment of this disease has a long duration, so only a venereologist can cope with this task. The choice of drugs and treatment regimen depends on many parameters.
In the treatment of syphilis, antibiotics (substances that inhibit the growth of bacteria) are actively used, which act on its causative agent - treponema pale. The main drugs to combat the disease are penicillin and its series of drugs. The pharmacological action of tablets and ampoules of penicillin is the same. The only difference is that they have different exposure times and directions. So let's take a look at pills for syphilis.
Tetracycline
This antibacterial agent has a bacteriostatic effect. The drug is prescribed for many diseases, including sexually transmitted diseases. The composition of one tablet contains 100 mg of tetracycline hydrochloride.
Dosage: adults - 250 mg every 6 hours, the maximum dose is 2000 mg per day; children from seven years old - 25 mg per kg / m of body every 6 hours.
Tetracycline has a number of contraindications: mycoses, renal and hepatic failure, age up to seven years, leukopenia, pregnancy, breastfeeding.
Side effects: abdominal pain, glossitis, nausea, vomiting, constipation, diarrhea, allergic reactions, rarely - Quincke's edema.
Price for 100 mg (20 pcs.) - from 47 rubles.
Ceftriaxone
Ceftriaxone is a new generation antimicrobial drug that is effective against microorganisms that develop in oxygen and in an oxygen-free environment. The action of this drug is due to the suppression of the cell membranes of pathogenic bacteria.
The dosage of Ceftriaxone is calculated individually and depends on the clinical condition of the patient. In the treatment of syphilis, the duration of therapy depends on the stage of the disease and ranges from 14 to 45 days.
The medicine has contraindications: increased sensitivity to the active ingredient. The antibiotic should be taken with caution in patients with ulcerative colitis, enteritis, chronic kidney and liver diseases, during pregnancy and lactation.
Price per bottle (1 g) - from 44 rubles.
Penicillin antibiotics
You can check out the following drugs.
Retarpen
A drug with an active β-lactam antibiotic of prolonged action. Effective against streptococci, treponemas, staphylococci and other microorganisms.
It is used to treat syphilis and other long-term diseases:
- inflammatory;
- infected wounds;
- erysipelas, tonsillitis.
It is prescribed as a prophylactic agent in the post-exposure period after communication with patients with syphilis and scarlet fever.
Dosage: treatment of primary syphilis - 2 injections (5 ml) with a weekly break; latent early or secondary syphilis - 3 injections with a break per week.
The medicine has contraindications: ulcerative colitis, pregnancy and lactation, hypersensitivity to the components of the drug.
Price per package (2,400 million IU) - from 2,400 rubles.
Extencillin
Extensillin is a macrolide antibiotic that has a bacteriostatic effect. Effective against chlamydia, streptococci, meningococci, leptospira.
The drug is indicated for the treatment of STIs (sexually transmitted infections), diseases of the genitourinary system, bronchopulmonary and skin pathologies.
The dosage is selected individually and depends on the form of the disease. In the treatment of syphilis, 1 intramuscular injection (2.4 million) is usually prescribed with an interval of 8 days.
Side effects: nausea and vomiting, development of pseudomembranous phlebitis, colitis, discomfort in the epigastric region, allergic skin reactions.
Price per bottle (2.4 million IU) - from 96 rubles.
Bicillin
Natural antibacterial drug of the penicillin group with an active active ingredient - benzathine benzylpenicillin. Suppresses the synthesis of cell walls and membranes, stopping their reproduction and growth. There are three types of bicillin, each of which has a different composition and concentration of active components.
It is used to treat various sexually transmitted diseases, including syphilis. When treating with bicillin, ascorbic acid and B vitamins are additionally prescribed (for the prevention of fungal infections).
What drug do you think is more effective against syphilis?
BicillinExtencillin
Side effects: nausea and diarrhea, dizziness, headaches, bronchospasm, unstable blood pressure, allergic skin reactions, rarely leukopenia, anaphylactic shock.
Bicillin is contraindicated in case of hypersensitivity to novocaine and the active substance, with bronchial asthma, urticaria, ulcerative colitis, hay fever. Possible therapy during pregnancy and lactation (under the supervision of a specialist).
Price per bottle (1.5 million IU) - from 47 rubles.
Doxilan
Bacteriostatic antimicrobial agent with an active ingredient - doxycycline. The drug is similar in pharmacological properties to tetracycline.
It is used to treat a number of infectious diseases, diseases caused by pathogenic microorganisms, soft tissue lesions, inflammation of the pelvic organs, pathologies of the ENT organs.
Dosage: for primary and secondary syphilis - no more than 300 mg of the drug per day for 2 weeks.
Side effects of taking the drug: headaches, dizziness, fungal infections, vascular collapse, constipation, diarrhea, glossitis, allergic reactions, Quincke's edema, changes in tooth enamel.
Doxilan is contraindicated in liver failure, under the age of 9 years, during pregnancy and lactation.
Price per pack 100 mg (20 pcs.) - from 29 rubles.
Syphilis pills during pregnancy
During pregnancy, syphilis is a rather serious problem that, according to statistics, 10% of women face. It is dangerous in that, without the help of a specialist, pathology can cause dire consequences.
A study for syphilis is carried out when a woman is registered with a consultation. If, after screening (passing tests), the diagnosis is confirmed, then two courses of therapy using pills will be prescribed:
- The first course of treatment is carried out inpatiently, the second prophylactic course can be carried out in a home outpatient clinic.
- Treatment during pregnancy significantly reduces the likelihood of a baby developing syphilis. In the course of therapy, as a rule, antibacterial agents (penicillin) are prescribed. This is one of the few drugs that does not affect the development of the fetus.
- In addition to penicillin, antibiotics of the penicillin group may be prescribed. The treatment regimen and the dose of the medication are determined only by the doctor and depend on the chosen remedy.
Often, the use of such therapy causes side symptoms: fever, dizziness, nausea. These reactions do not pose a threat to the life of the fetus and most often go away on their own. However, if the tablets cause cramps or pain in the abdomen, you should immediately consult a doctor.
It is forbidden to prescribe medication for oneself, even with adherence to the treatment regimen. Uncontrolled use of antibiotics can cause many diseases.
Can syphilis be cured with pills?
For sexually transmitted diseases, as a rule, various forms of drugs are used. The tablets are used as antiallergenic, immunostimulating and auxiliary agents. Such treatment is most often prescribed in the initial stages, at a later date, combination therapy with the use of tablets and injections is indicated.
Oral therapy is also possible when destructive changes in the gluteal muscle occur due to a long course of injections. In this case, the entire blow falls on the gastrointestinal tract. In addition, prolonged use of antibiotics in tablet form can provoke peptic ulcer disease, cause inflammation of the liver.
Each patient is assigned an individual treatment regimen, it directly depends on the following conditions:
- drug tolerance;
- form and stage of the disease;
- the presence of other diseases at the time of screening;
- the patient's age;
- the physical condition of the patient;
- the patient's living conditions.
The early stages of syphilis are much easier to treat, in this case, antibiotic therapy is considered optimal. Such treatment takes no more than three months and most often leads to a complete recovery. When the disease is in advanced form, treatment measures can last for more than two years. In this case, special therapy (toxic) with derivatives of bismuth (Biyohinol) or arsenic (Novarsenol, Miarsenol) is carried out.
A patient is considered healthy if no relapses occur within 5 years after therapy. Today, syphilis is effectively treated at all stages, however, for a positive lasting result, the help of a venereologist is needed, as well as strict adherence to all prescriptions.
Expert opinion
Artem Sergeevich Rakov, venereologist, over 10 years of experience
Syphilis is a dangerous disease. Attempts to heal on his own will not destroy him, but will only aggravate the situation. At the same time, a complete refusal of therapy will inevitably lead to a deterioration in the state of health, a gradual shutdown of organs and, as a result, to the slow death of the infected.
With the correct selection of medicine and strict observance of the instructions of the doctors by the patient, he has a chance to permanently cope with the disease. The main factors in the successful treatment of syphilis are timely diagnosis, long-term complex therapy and strict adherence to the recommendations of a specialist.
You can also watch the video in this article, where the doctor will tell you about the possibility of treating syphilis.
Syphilis is a sexually transmitted disease. When infected with treponema pale, the skin, internal organs, mucous membranes, nervous and skeletal systems are affected. The disease is subject to mandatory treatment in specialized dispensaries under the supervision of a physician. But at the initial stage of its development, doctors are allowed to carry out treatment with pills and injections at home.
General information and symptoms
Syphilis is a chronic sexually transmitted disease caused by the bacterium treponema pallidum. The main route of transmission of the disease is sexual, and infection from mother to child during childbirth is also possible. The disease affects mucous membranes, skin, organs and tissues, bone and nervous system.
When a person becomes infected with pale treponema, general symptoms of the disease appear:
- general malaise;
- weakness;
- migraine;
- insomnia.
Syphilis is divided into three stages. The table describes the symptoms of the disease, which appear depending on the stage of the pathological process.
| Stage | Characteristic | Photo |
| Primary syphilis | During the time, painful appears on the labia of women or the head of the penis of men. This is an element with a dense base and smooth brown-red edges. Ulcers form at the site of the introduction of the pathogen into the body. After 2 weeks, the lymph nodes that are in the immediate vicinity of the rash enlarge. This is a sign that pale treponema is carried with the bloodstream throughout the body and affects the vital organs of a person. The ulcer heals on its own after a month, but the infection continues to develop. By the end of the first period, the patient develops specific symptoms:
During the first period, doctors prescribe antibiotics for home treatment. | Chancre with syphilis |
| Secondary syphilis | After the end of the first phase, it develops. This period is characterized by the following signs:
If the disease is not treated with antibiotics, it turns into a latent course that lasts for years with periods of exacerbation. During relapse, the rash is less, the elements are faded. The patient's hair falls out, a flesh-colored overgrowth appears in the genital area |
Rash with secondary syphilis |
| Tertiary syphilis | Pale treponema affects vital organs, gunas or foci of inflammation appear on the mucous membranes, organs, eyes and bones of a person. The nasal bridge sinks in, during the meal, food is brought in. Nerve cells of the brain and spinal cord die, paralysis occurs, dementia |
Tertiary syphilis |
It is allowed to be treated with pills and injections for syphilis at home only at the first stage of the disease. During the secondary and tertiary stages, the patient is in the hospital under the supervision of a doctor.
Antibiotics
Treating syphilis is a complex task that requires complex action. The therapy is based on medicines: antibiotics and antibacterial agents.
To treat syphilis, the patient needs a course of antibiotic therapy. Doctors prescribe drugs of the penicillin group, as pale treponema is the least resistant to them. The agent is prescribed for oral administration or as an injection. In advanced cases, a complex effect is necessary: the use of penicillin in the form of tablets and an injection of an identical medication in an hour.
Effective medications for treponema pale:
- Retarpen;
- Bicillin;
- Extensillin and others.
The drugs of the penicillin group act on treponema pale and have a low threshold for the development of an allergic reaction.
If the patient has an individual intolerance to the penicillin series, then the doctor decides on the appointment of macrolide group agents:
- midecamycin;
- Rovamycin;
- Sumamed;
- erythromycin and others.
Syphilis tablets are prescribed at the initial stage of the development of the disease, and the course of treatment is 3-4 months. The drug and dose are selected individually.
At an advanced stage, when the disease becomes chronic, therapy is carried out for a long period, which is at least a year. In this case, toxic drugs are used, since treponema becomes resistant to antibiotics.
The table describes effective medicines for treating syphilis at home.
| A drug | Characteristic | Photo |
| Rovamycin | The drug belongs to the macrolide group, has a persistent bactericidal effect. Affects the causative agents of meningitis, chlamydia and syphilis. It is prescribed in complex therapy. The medicine is produced in tablet form and in the form of a powder for preparing a solution for intravenous administration. The tablets are well tolerated by humans, but if the dosage is incorrect, nausea and vomiting appear |  |
| Doxilan | The active ingredient of the drug is doxycycline. The tablets have antimicrobial effect. Affect treponema pale. The duration of treatment is 2 weeks. The development of side reactions is possible:
|  |
| Miramistin | Miramistin is highly effective in the treatment of sexually transmitted diseases. Affects gram-positive and gram-negative bacteria, including treponema pallidum |  |
| Bicillin | Preparations of the penicillin group of natural origin. The action is based on suppressing the synthesis of cell membranes of the causative agent of the disease, which prevents their further growth and reproduction. Bicillin acts on gram-positive and gram-negative microorganisms. You cannot use it during pregnancy. To reduce the risk of spreading a fungal infection while taking the drug, doctors prescribe a course of vitamins C and B |  |
| Penicillin | A common drug with a wide spectrum of action, available in the form of tablets or solution for injection. It is prescribed in the form of injections, since the solution has a high percentage of effectiveness. Penicillin is not used for individual intolerance |  |
| Cephobid | Cefobit or cefoperazone has a broad spectrum of action. The drug is active against Staphylococcus aureus, treponema pale, chlamydia and other pathogenic microorganisms. In case of an overdose, side effects from the gastrointestinal tract develop:
If you are prone to allergic reactions, the medicine is not prescribed. |  |
| Cefotaxime | It is a third generation antibiotic that can be used during pregnancy. Used in the treatment of syphilis. Contraindications include individual intolerance to the penicillin group of drugs. Can't use it for liver dysfunction |  |
| Minoleksin | Minolexin is a tetracycline drug with high bacteriostatic properties. Available in capsule form for oral administration. It is not prescribed simultaneously with penicillin, as the effectiveness of Minolexin decreases. The duration of treatment is 20 days. |
Minoleksin |
| Bismoverol | An anti-syphilitic drug that is used at every stage of therapy. Used for adults and children. You can not use it for some diseases: diabetes mellitus; dysfunction of the liver and kidneys; acute heart failure |
Tablets, injections and ointments for syphilis are selected by the doctor on an individual basis. Self-medication is inappropriate.
At the advanced stage of pathology, the patient is prescribed potent drugs or injections. For example, the antibiotic Azaran is a modern medicine of the 3rd generation of group III cephalosporins. Has a bactericidal effect, inhibits the development of pale treponema.
Available only in solution for intramuscular injection. The components of the drug are absorbed into the bloodstream, providing a quick therapeutic effect. The assimilation by cells and tissues reaches 100%, which allows for a quick recovery and elimination of treponema from the human body.
- Clavocin;
- ceftriaxone;
- Augmentin and others.
All information is provided for informational purposes only. Given the possibility of a latent course, serious complications, a qualified specialist should deal with the treatment. Only a doctor is able to choose methods of correction that help to completely get rid of treponema pale. Self-medication mutes clinical manifestations and can be fatal to human health.
Syphilis pills are prescribed to patients only after a complete examination and diagnosis. The disease develops as a result of the ingestion of a pathogenic pathogen - pale treponema, which affects not only the mucous membranes, but also the skin, bones, joints, and the nervous system. Syphilis therapy is carried out with antibacterial drugs.
The best syphilis remedy
Syphilis therapy takes a long time in case of untimely detected infection of the patient.
If antibodies to pathogenic microorganisms are found in the blood and the patient has symptoms of a sexually transmitted disease, the doctor prescribes medications. Currently, there are a large number of effective medications to cope with the infection and prevent the development of possible complications.
Medicines and pills for syphilis are prescribed at any of its stages. The mainstay of treatment is antibiotics and preparations containing iodine and bismuth. In the past, doctors have prescribed mercury-based products to patients, to which pathogens are highly susceptible. Such medicines were highly toxic and led in more than half of the cases to death caused by intoxication.
Currently, patients are prescribed an effective drug - penicillin. It is highly effective against treponema pallidum. Doctors prescribe the medicine in tablet form at the initial and secondary stages of the disease. In the third phase, patients are given injections with penicillin or its derivatives. When severe disorders of gluteal muscle tissue appear from injections, it is recommended to take pills.
The following drugs are most effective:
- Penicillins: retarpen, bitillin, extencillin. These antibacterial agents are able to suppress the activity of spirochetes in a short time, but in some patients they cause allergies and other side effects.
- Macrolides and fluoroquinolones: clarithromycin, erythromycin, ofloxacin. They are prescribed when the patient develops an individual intolerance to medications from the penicillin group.
Primary syphilis responds to drug therapy much more easily compared to tertiary and advanced forms of the disease. Early treatment takes three months, after which patients recover completely. In the late phase of syphilis, pale treponema acquires pronounced drug resistance. In such cases, doctors use a stronger medication containing arsenic and bismuth derivatives.
Necessary examinations before prescribing the drug
An external examination and the presence of symptoms of syphilis alone is not enough for a diagnosis and drug therapy. When pale treponema is detected using nonspecific tests, a number of treponemal analyzes are performed, which have a higher sensitivity.
The use of several techniques during the diagnosis of a sexually transmitted disease is necessary to exclude false positive results that are possible with certain chronic pathologies, pregnancy.
Latent syphilis also requires diagnosis using specific test systems (RIF, ELISA, RPGA).
With the presence of vivid signs of syphilis, the presence of solid chancre and ulcerative formations in patients, an additional examination is carried out:
- biopsy of lymph nodes in the presence of foci of inflammation;
- analysis of cerebrospinal fluid from the spinal canal with signs of dysfunction of the nervous system;
- scraping when skin rashes are found;
- electrocardiogram and radiography when the patient develops changes in the cardiovascular, skeletal systems, joints.
Consultation with other specialists is appointed when violations of the work of internal organs are detected and there are signs of damage to them by pathogenic microorganisms.
Syphilis treatment regimens and dosage
Drugs for the treatment of syphilis are selected depending on the form of the disease, existing pathologies and intolerance to one or another medication.
Syphilis pills for men
Treatment of syphilis in men is carried out with the following drugs:
- Group of tetracyclines: doxycycline (0.3 g per day for 10 days), tetracycline (0.25-0.5 g every 6 hours), vibramycin (0.2 g once with a weight of more than 50 kg, with a lower body weight of 4 mg per kg once, then 2 mg per kg), minolexin (no more than 0.4 g per day).
- Penicillins: phenoxymethylpenicillin (the dose is selected individually), V-penicillin (0.5 g twice a day for 7 days).
- Macrolides: rovamycin (2 tablets, 3 million units each), wilprafen (0.5 g three times a day), erythromycin (0.25-0.5 g every 6 hours).
After the end of treatment with antibacterial medicines, the patient is prescribed drugs that improve the functioning of the immune system, as well as multivitamins. When signs of chronic fatigue appear, the patient is prescribed a course of adaptogens.
Preparations for women
Therapy of an infectious disease caused by spirochetes in women is carried out by the following drugs:
- monoclin (up to 2 tablets per day);
- spiramycin (6 million units three times a day);
- doxycycline (0.3 g for 10 days);
- erythromycin (0.25 g groove at 6 o'clock).
Depending on the degree of tolerance of antibacterial drugs, dosages may vary. If necessary, the drug is changed to another, similar in action.
At the end of the antibacterial course, doctors recommend drinking products containing beneficial bacteria. Probiotics not only help restore the intestinal microflora, but also strengthen the immune system. Linex, bifiform, bifidumbacterin are highly effective.
During pregnancy
- Erythromycin 0.5 g 2-3 times a day for two weeks when syphilis is detected in latent, primary or secondary forms.
- Erythromycin 0.5 g 4 times a day for 15 days with late stages of venereal disease, neurosyphilis.
After treatment with antibacterial drugs, women undergo nonspecific blood tests once a month before childbirth. The child, regardless of whether he has a symptom of infection or not, is undergoing benzathine penicillin therapy (injection of 50 thousand units per kg). With the initial diagnosis of syphilis after the first year of the baby's life and the absence of infection, treatment is not carried out.
If the doctor suspects the presence of pale treponema in the child's body, a two-week therapy with drugs from the penicillin group is prescribed.
If the mother is infected, after taking preventive measures, the baby's blood is regularly taken for serological control. Preventive examinations are carried out throughout the year. When diagnosing a late congenital form of syphilis, the child is prescribed drugs from the group of penicillins and drugs containing bismuth. When symptoms of intolerance to these medications appear, therapy with oxacillin, erythromycin, ampicillin is performed. After using antibacterial agents, a course of nystatin and antihistamines is prescribed.
Syphilis injections
When treponemal infection is detected at the secondary and tertiary stages, doctors prescribe injections that are carried out intramuscularly into the upper outer zone of the buttock. Intravenous injection is rarely given. The advantage of injections is fast action with minimal impact on the digestive tract. Medicines injected intramuscularly are eliminated from the body in a short time.
- bicillin-1 time per day;
- bicillin-2 twice a day;
- bitillin-5 three times a week.
The accumulation of the drug Bicillin-1 in the body does not occur. It is not prescribed for secondary and tertiary forms of syphilis, pregnancy, congenital form of the disease, the presence of signs of dying off of hair follicles, the appearance of whitish spots on the skin, suspected visual and hearing impairment associated with exposure to infection.
With the development of allergic reactions to drugs of the penicillin series, the patient is prescribed other antibacterial agents:
- Tetracyclines. The injections are given twice a day. The medication is not used for violations of the kidneys, hearing aids, in the treatment of children under 7 years of age.
- Doxycycline. It is administered intramuscularly twice a day. In this case, the patient should not stay in direct sunlight for a long time. In childhood, doxycycline is not recommended for children due to its negative effects on the skeletal system.
- Ceftriaxone. The medication is injected intramuscularly once a day. With treponemal infection, it is less effective than penicillin antibiotics. When carrying out drug therapy, the patient is allowed not to be hospitalized.
When signs of a fungal infection occur, which often develops after antibiotic treatment, patients are prescribed nystatin. The occurrence of an allergic reaction requires the use of an antihistamine.
Any deterioration in the patient's condition against the background of treatment with antibacterial drugs requires an immediate visit to a venereologist or therapist.
Cost of medicines for syphilis
The average price for antibacterial drugs is shown in the table.
| Name | Cost, $ |
tablet form 0.25 g 20 pcs solution 0.1 g 1 bottle 0.1 g 50 vials |
|
| Tetracycline tablets 0.1 g 20 pcs | 0,8 |
| Ceftriaxone solution 1.0 1 ampoule 1.0 50 ampoules 1,0 10 ampoules 0.5 50 ampoules |
|
| Doxycycline capsules 0.1 g 10 pcs bottle 0.1 g 5 pcs |
|
| Vibramycin capsules 0.1 g 10 pcs |
|
| Wilprafen 0.5 g 10 tablets | 10,5 |
| V-penicillin 0.5 mg 30 pcs | 15,8 |
| Minoleksin capsules 0.1 g 20 pcs |
|
| Rovamycin tablets 3 million IU 10 pieces 1.5 million IU 16 pcs |
|
| Spiramycin 3 million IU 10 pcs | 3,7 |
| Unidox solutab tablets 0.1 g 10 pcs |
|
| Phenoxymethylpenicillin 0.25 g 10 tablets | 0,4 |
Certain types of antibacterial drugs require a doctor's prescription.
Prophylaxis pills
For preventive purposes, doctors do not prescribe drugs against treponemal infection due to the large number of possible side effects. Treatment of syphilis is carried out in most cases with antibacterial agents, which, with prolonged use, can be addictive and reduce the sensitivity of pathogenic microorganisms.
The basis for the prevention of syphilis and other sexually transmitted diseases is barrier contraception. Using condoms every time you have sex prevents pathogenic bacteria from entering the body of a healthy partner.
Promiscuous sexual intercourse increases the risk of infection with treponema pallidum.
For preventive purposes, doctors recommend the use of drugs that have antiseptic and antibacterial effects (chlorhexidine, miramistin). The procedure for processing the genitals must be carried out within the first two hours after intercourse. During this period, pathogenic microorganisms are located only on the surface of the skin and mucous membranes and do not penetrate into the deep layers.
Venereologists advise to regularly undergo tests for syphilis, which includes conducting nonspecific tests. If a person is infected with pale treponemas, the rest of the family must be diagnosed without fail. The course of medicines is prescribed only after the detection of the pathogen. To prevent infection of healthy people, the patient needs to use only personal hygiene items: a brush, a towel, a washcloth, and underwear. Cutlery for the patient should be distinguished separately.
To prevent the development of congenital forms of syphilis, expectant mothers should be examined before conception. If pathogenic bacteria are detected, treatment should be carried out immediately. During infection of the pregnant woman, a course of antibacterial drugs is prescribed, and after childbirth, for prophylactic purposes, drugs are administered to the child once.
Syphilis is a serious illness that requires immediate treatment after a treponemal infection is detected. Tablet forms of drugs are prescribed in the early stages. Oral administration is convenient for patients and does not require hospitalization. With advanced syphilis and the development of complications from the digestive system, injections are prescribed to patients. If there are signs of intolerance to tablets, you should consult a doctor.
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