Citramon helps with temperature. Can "Citramon" be given to children: instructions for use, indications and contraindications, age limit

Date of: 05.03.2020

Citramon belongs to the group non-narcotic drugs, analgesics. It's complex medical device, the active ingredients of which are a compound of paracetamol, caffeine and acetylsalicylic acid.

Due to the complex effect, the drug has an anti-inflammatory, analgesic, analgesic, vasodilating effect on the centers of inflammation. Citramon is used to reduce the effects of various pains of low intensity - headaches, toothaches, muscle aches, periodic spasms.

It is also actively used in febrile conditions during influenza. To understand what the drug helps with and when it is prescribed, you need to consider its composition and action.

Clinical and pharmacological group

Analgesic-antipyretic combined composition.

Terms of sale from pharmacies

Can buy without a doctor's prescription.

Price

How much does Citramon cost in pharmacies? average price is at the level of 11 rubles.

Composition and form of release

To date, the number of manufacturers of the drug is steadily growing, so the composition of Citramon will be slightly different. However, the main active substance is not subject to change.

The composition of Citramon "classic" included:

0.25 g of acetylsalicylic acid (Acidum acetylsalicylicum);
0.17 g phenacetin (Phenacetini);
0.027 g caffeine (Caffeine);
0.021 g of citric acid (Citric acid);
and 0.014 g cocoa.

This composition has now ceased to exist, and phenacetin was banned, as it can cause serious complications and side effects. Most often, the composition of the combined drug now includes the main three components:

aspirin (Acidum acetylsalicylicum);
paracetamol (Paracetamoli);
and caffeine.

Different types of Citramon

Depending on the manufacturer, Citramon comes with a different composition and name. To date, the following varieties are produced:

Citramon P - contains aspirin, caffeine and paracetamol. The use of Citramon P is contraindicated in persons under 14 years of age. The dosage for adults is 1 to 2 tablets three times a day. There should be a gap between doses (at least 6 hours).
Citramon Forte - contains, in addition to aspirin, caffeine and paracetamol, as well as citric acid. Auxiliary components: cocoa, potato starch, magnesium stearate. The addition of citric acid to the drug is not accidental; it stabilizes cellular respiration at the biochemical level. Assign Citramon Forte to persons aged 14 years and above, the dosage is 1-2 tablets up to three times a day.
Citramon Darnitsa is the most popular among the rest. The composition includes aspirin, paracetamol, caffeine, citric acid. Auxiliary components: starch, cocoa, calcium stearate and polyvinylpyrrolidone. The rules of application do not differ from previous drugs.
Citramon Ultra - consists of acetylsalicylic acid, paracetamol and caffeine. Available in the form of capsules, appoint 1-2 capsules up to a maximum of four times a day. Daily dose should not exceed eight capsules.

Pharmacological effect

Citramon is a combination drug and its therapeutic effect due to the properties of the active components that make up its composition:

Paracetamol has antipyretic and analgesic properties, as well as a moderately pronounced anti-inflammatory effect.
Acetylsalicylic acid has antipyretic and anti-inflammatory properties, and this substance also relieves pain caused by inflammation and reduces blood clotting, thereby stimulating blood circulation in the focus of inflammation.
Caffeine produces an exciting effect on the central nervous system and stimulates the work of the psychomotor centers of the central nervous system. It increases the light blood vessels and reduces feelings of drowsiness and fatigue. Caffeine is also known for its stimulating effect on physical and mental activity. It has caffeine and a mild analgesic effect.

Citramon raises or lowers blood pressure?

This question is often asked by patients. Due to the content of caffeine, which stimulates the central nervous system, increases tone and pressure, pressure can also increase from taking Citramon, despite the fact that it is contained in small doses. Moreover, you should be careful if you drink tea, cocoa or coffee and take Citramon - there is a risk of an overdose of caffeine. If you have low blood pressure and suffer from a headache, then in the absence of contraindications, you can take a Citramon tablet, which will relieve pain and slightly increase blood pressure.

Indications for use

Basically, these are mild and moderate pains of various locations:

headache;
migraine;
pain during menstruation;
neuralgia;
pain in the joints and muscles;
fever body with influenza, colds and rheumatic diseases.

Citramon is unlikely to cope with severe pain, therefore, in more complex cases, remedies that have these effects to a greater extent are recommended.

Citramon for headaches

For headaches, this is one of the most effective means, which is usually in the first aid kit. The combination of its components provide quite fast action– elimination of pain, increase of mental activity and working capacity. He copes with pain of various etiologies, including migraines. Not being a narcotic medicine, it does not cause addiction and dependence.

It is only undesirable to mix Citramon with other drugs against headaches - such issues should be discussed with the doctor.

Contraindications

Absolute:

glaucoma;
hemophilia and other blood clotting disorders;
operations that are accompanied by heavy bleeding;
simultaneous reception of methotrexate in an amount of more than 15 mg per week;
sleep disturbance, increased nervous excitability;
deficiency of glucose-6-phosphate dehydrogenase;
gastrointestinal bleeding or perforation;
erosive ulcerative lesions gastrointestinal tract(GIT) in the acute phase;
history of peptic ulcer;
hypoprothrombinemia, hemorrhagic diathesis;
portal hypertension;
avitaminosis K;
chronic heart failure III and IV functional class according to the classification of the New York Heart Association (NYHA);
arterial hypertension (III degree);
incomplete or complete combination bronchial asthma, recurrent polyposis of the paranasal sinuses and nose, as well as intolerance to non-steroidal anti-inflammatory drugs (NSAIDs), such as ASA;
severe hepatic and / or renal failure;
During pregnancy and breastfeeding;
age up to 18 years (with febrile syndrome) or up to 15 years (with pain syndrome);
hypersensitivity to the components of Citramon P.

The drug is prescribed with caution in the following cases:

chronic heart failure (I and II functional class according to NYHA);
epilepsy, tendency to convulsive seizures;
simultaneous use of methotrexate in an amount of less than 15 mg per week, as well as glucocorticosteroids, NSAIDs, antiplatelet agents, anticoagulants, selective inhibitors serotonin reuptake;
alcoholism;
renal and / or hepatic insufficiency of medium and mild degree;
chronic obstructive pulmonary disease;
gout;
coronary artery disease;
cerebrovascular diseases;
peripheral arterial disease;
smoking;
elderly age.

Appointment during pregnancy and lactation

During pregnancy (I and III trimesters) and during breastfeeding the drug is contraindicated. In the second trimester of pregnancy, the drug should be used with caution, balancing the intended benefit to the mother and the potential risk to the fetus.

Dosage and method of application

As indicated in the instructions for use, Citramon tablets are intended for oral administration, preferably after meals. The average therapeutic dosage for adults and adolescents over 15 years of age is 1-3 tablets 2-3 times a day, depending on the severity of pain or fever.

The maximum daily dosage should not exceed 6 tablets. The drug is not intended for a long course of therapy, the maximum duration of taking tablets should not exceed 5 days.

Adverse reactions

Side effects of Citramon:

increased blood pressure, arrhythmia, tachycardia;
aggravation of heart failure, manifestation of its latent forms (with prolonged use);
dizziness, insomnia, agitation, anxiety, headache, tinnitus, hearing and vision impairment, aseptic meningitis;
gastralgia, anorexia, nausea, the formation of erosions and ulcerative elements on the mucosa of the digestive canal, gastric and intestinal bleeding;
liver failure;
hypersensitivity reactions (including the development of symptoms of the Fernand-Vidal triad);
interstitial nephritis, nephrotic syndrome, necrotic papillitis, with prolonged use - renal failure;
anemia, thrombocytopenia, leukopenia;
acute fatty hepatosis, toxic hepatitis, acute hepatic encephalopathy (Reye's syndrome);
development of tolerance and weak psychological dependence(at long-term use high doses drug);
drug headache after the abolition of Citramon (if the drug has been used for a long time).

In animal experiments, the teratogenic effect of the drug on the fetus was also proven.

Overdose symptoms

Overdose symptoms include nausea, vomiting, dizziness, epigastric pain. In severe cases, there is drowsiness, lethargy, loss of consciousness, convulsions, bronchospasm, bleeding, shortness of breath.

If these signs appear, you should immediately seek medical attention medical care.

Treatment includes gastric lavage, enterosorbents, saline laxative. Forced alkaline diuresis, alkalizing agents, measures to restore bcc and acid-base balance are shown.

special instructions

Before you start using the drug, read the special instructions:

In patients with a predisposition to accumulation uric acid taking the drug can provoke an attack of gout.
Avoid drinking alcohol while taking it (increased risk of gastrointestinal bleeding and liver toxicity).
Acetylsalicylic acid slows down blood clotting. If the patient is to undergo surgery, the doctor should be warned about taking the drug.
With prolonged use of the drug, monitoring of peripheral blood and functional state liver.
Patients with hypersensitivity or with asthmatic reactions to salicylic acid and its derivatives, including acetylsalicylic acid, can only be prescribed with special precautions (in the emergency room).
Acetylsalicylic acid has a teratogenic effect; when used in the first trimester, it leads to a malformation - splitting of the upper palate; in the III trimester - to inhibition labor activity(inhibition of Pg synthesis), to close ductus arteriosus in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the pulmonary circulation. It is excreted in breast milk, which increases the risk of bleeding in a child due to impaired platelet function.

Children under 15 years of age should not be prescribed drugs containing acetylsalicylic acid, because in the case of viral infection they can increase the risk of Reye's syndrome. Symptoms of Reye's syndrome are prolonged vomiting, acute encephalopathy, liver enlargement.

Compatibility with other drugs

When using the drug, it is necessary to take into account the interaction with other drugs:

Caffeine accelerates the absorption of ergotamine.
With the simultaneous administration of the drug and alcohol-containing liquids, the risk of toxic liver damage increases.
Enhances the action of heparin, indirect anticoagulants, reserpine, steroid hormones and hypoglycemic drugs.
Barbiturates, rifampicin, salicylamide, antiepileptic drugs and other stimulants of microsomal oxidation contribute to the formation of toxic paracetamol metabolites that affect liver function.
Simultaneous use with other non-steroidal anti-inflammatory drugs, methotrexate increases the risk of developing side effects.
Reduces the effectiveness of spironolactone, furosemide, antihypertensive drugs, as well as anti-gout drugs that promote the excretion of uric acid.
Metoclopramide accelerates the absorption of paracetamol. Under the influence of paracetamol, T1 / 2 of chloramphenicol increases 5 times. When taken repeatedly, paracetamol may enhance the effect of anticoagulants (dicoumarin derivatives).

According to Wikipedia data, traditionally Citramon tablets included 240 mg acetylsalicylic acid (ASA), 180 mg, 30 mg caffeine , 15 mg cocoa, 20 mg citric acid.

However, at present classic recipe the manufacture of the drug is not used due to the withdrawal from circulation of one of its active components - phenacetin (This is due to the high substance nephrotoxicity ).

Numerous manufacturers produce medicines with the word "Citramon" in the name, but they all have a slightly modified composition, in which, as analgesics And antipyretic instead of phenacetin used .

In tablets from different manufacturers, the uniformity of active substances is maintained, however, the concentration of each of them may differ.

Citramon P, Citramon U and Citramon M contain active ingredients (ASA, paracetamol And caffeine ), for example, are contained in the same concentration as in the original preparation. But in the composition of Citramon-Forte, their concentration is already different: each tablet contains 320 mg of ASA, 240 mg paracetamol and 40 mg caffeine .

The composition of the tablets Citramon Borimed includes 220 mg ASA, 200 mg paracetamol and 27 mg caffeine . The concentration of these substances in Citramon-LekT tablets is 240 mg, 180 mg and 27.5 mg, respectively.

But the main difference between Citramon Ultra and Citramon is the presence of a film shell, which facilitates the swallowing of the tablet, acts as a reliable barrier between the mucosa of the digestive canal and the active ingredients contained in the tablets (in particular, the shell protects the stomach from the aggressive effects of ASA) and accelerates the absorption of the drug.

Release form

All manufacturers produce Citramon in the form of light brown tablets with a cocoa smell. The tablets are heterogeneous in appearance, have blotches and inclusions.

They are produced packed in strips (6 pieces each) or blisters (10 pieces each). Packing No. 10*1, No. 6*1 and No. 10*10.

pharmachologic effect

The action of the drug is aimed at relief of pain, fever And inflammation .

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Citramon is a combined remedy, the action of which is due to the properties of the components contained in it ( non-narcotic analgesic , Psycostimulator and NSAIDs).

ASA relieves fever and inflammation, relieves pain (especially if the pain is caused by an inflammatory process), has a moderate antiplatelet action , prevents the formation blood clots , improves microcirculation in the focus of inflammation.

Paracetamol reduces the intensity of pain, knocks down the heat, has a weak anti-inflammatory action . The properties of this substance are associated with its effect on the thermoregulatory center located in the hypothalamic region and a weakly expressed ability to inhibit the formation of Pg in peripheral tissues.

Caffeine has a direct excitatory effect on the central nervous system, which manifests itself in the form of increased excitation processes in the cortex hemispheres brain vasomotor and respiratory centers, increase motor activity and strengthening positive conditioned reflexes.

Stimulates mental activity, temporarily reducing or eliminating drowsiness and fatigue, shortens reaction time. Reduces platelet aggregation .

As part of Citramon tablets caffeine present in low concentration. Because of this, the substance has practically no stimulating effect on the central nervous system, however, it improves the tone of the brain vessels and helps to accelerate blood flow.

Combination of ACK and paracetamol potentiates analgesic effect drug. How anesthetic , and antipyretic effects ACK and paracetamol increase with the simultaneous use of these substances with caffeine .

Pharmacokinetics

After oral administration, the components contained in the tablets are absorbed quickly and almost completely. Caffeine at the same time, it helps to increase F (bioavailability) of ASA and paracetamol .

During absorption, he and ASA are intensively biotransformed with the formation of pharmacologically active metabolites. From ASA in the process of deacetylation in the liver and intestinal wall is formed .

Under the influence of the hepatic CYP1A2 isoenzyme, caffeine forms dimethylxanthines ( paraxanthine and theophylline ).

TSmax of all active components of Citramon - from 0.3 to 1 hour. In blood plasma from 10 to 15% paracetamol and approximately 80% of the accepted dose of ASA are associated with albumin condition.

All components of the tablets easily penetrate into any fluids and tissues of the body (including easily overcome the placental barrier and enter the breast milk). Minor concentrations of salicylates are found in brain tissues, while levels caffeine And paracetamol comparable to plasma levels of these substances.

With the development acidosis ASA passes into a non-ionized form, due to which its penetration into the tissues of the NS increases.

Metabolism active substances and proceeds in the liver. ASA has 4 metabolites (gentisuronic and gentisic acids, salicylovophenol glucuronide, salicylurat). Paracetamol forms sulfate (80% of the total) and paracetamol-glucuronide (both pharmacologically inactive), as well as a potentially toxic substance - N-acetyl-benziminoquinone (about 17% of the total).

Metabolites caffeine - derivatives of uridine, mono- and dimethylxanthines, mono- and dimethyluric acid, di- and trimethylallantoin.

Caffeine affects the pharmacokinetics paracetamol , slightly increasing (up to 20-25%) the formation of N-acetyl-benziminoquinone.

Metabolites are excreted by the kidneys. About 5% paracetamol, about 10% caffeine and about 60% of salicylates are excreted unchanged.

The elimination half-life is from 2 to 4.5 hours (all components of the drug are excreted at approximately the same rate). An increase in the dose of Citramon leads to a slowdown in the excretion of ASA in comparison with other substances up to 15 hours.

In smokers, on the contrary, there is an acceleration of excretion caffeine in comparison with other components of the drug.

Indications for Citramon's use

Why Citramon P?

When asked what Citramon P helps with, the manufacturer in the annotation to the drug replies that the use of tablets is advisable to relieve pain of mild and moderate severity, as well as to alleviate the patient's condition when febrile syndrome , which are accompanied And .

Effective Citramon from the head (including migraine attacks), with joint and muscle pain, algomenorrhea .

What are Citramon-LekT tablets for?

Indications for the use of Citramon-LekT are the same as for other drugs, which are based on ASC , paracetamol And caffeine , namely: pain syndrome at algomenorrhea , neuralgia , myalgia , arthralgia , head And toothache , migraine .

The drug can also be used as a remedy for fever with fever against the background And .

Does Citramon help with toothache?

Toothache is one of the indications for the use of the drug. The effectiveness of Citramon is due to the properties of its constituent NSAIDs, non-narcotic analgesic And psychostimulant .

Reinforcing the action of each other, these components have a complex effect on the body, relieving any (including toothache) pain, especially if this pain is associated with inflammation. With an exacerbation chronic pulpitis , against which the temperature often rises, Citramon helps not only to relieve pain and reduce the severity of inflammation, but also has antipyretic action .

Contraindications

The instructions list the following contraindications for Citramon:

full or partial combination recurrent nasal/sinus polyposis , and intolerance to NSAIDs or ASA (including history);
hypersensitivity to the components of the tablets;
erosive And ulcerative lesions of the gastrointestinal tract in the acute phase;
gastric or intestinal bleeding ;
portal hypertension ;
hemophilia ;
hypoprothrombinemia ;
hemorrhagic diathesis ;
beriberi K ;
IHD of severe course;
pronounced arterial hypertension ;
kidney failure ;
deficiency of the cytosolic enzyme G6PD;
pregnancy (especially its first and last trimesters);
lactation;
increased excitability;
dissecting aortic aneurysm ;
sleep disorders;
surgical interventions accompanied by bleeding;
children's age (in children under fifteen years of age with hyperthermia against the background of a viral infection, there is a high probability of developing Reye's syndrome );
concomitant use anticoagulants .

Relative contraindications are and existing liver pathology .

Side effects

Side effects of Citramon:

gastralgia , anorexia , nausea, the formation of erosions and ulcerative elements on the mucous membrane of the digestive canal, gastric and intestinal bleeding;
liver failure ;
hypersensitivity reactions (including the development of symptoms Fernand-Vidal triads );
interstitial nephritis , nephrotic syndrome , necrotic papillitis , with long-term use - ;
anemia , thrombocytopenia , leukopenia ;
acute fatty liver , toxic hepatitis , acute hepatic encephalopathy (Reye's syndrome );
aggravation heart failure , manifestation of its latent forms (with prolonged use);
dizziness, insomnia, agitation, anxiety, headache, tinnitus, hearing and vision disorders, aseptic meningitis ;
increase in blood pressure, , ;
development of tolerance and weak psychological dependence (with prolonged use of high doses of the drug);
drug headache after the abolition of Citramon (if the drug has been used for a long time).

In animal experiments, the teratogenic effect of the drug on the fetus was also proven.

Citramon tablets: instructions for use

Medicines from different manufacturers excellent composition, and since the active substances in them are often contained in different concentrations, you should read the instructions very carefully so as not to mistakenly exceed the permissible daily dose.

Common to all drugs is that as an analgesic, they can be used for a maximum of five, as an antipyretic - three days.

Instructions for use Citramon P and Citramon-LekT

Citramon P and Citramon-LekT can be taken from the age of fifteen. Tablets are drunk one at a time 2-4 rubles / day (during or after meals). The break between doses should be at least four hours. The average dose is 3-4 tablets per day.

Citramon from headache high intensity (as well as in other cases when it is necessary to relieve severe pain) you can take 2 pieces at once. The permissible upper limit of the daily dose is 8 tablets.

Treatment lasts from one week to ten days.

If necessary, the doctor may prescribe a different dose of the drug or choose a different treatment regimen.

Instructions for use Citramon forte

Citramon-Forte is used in patients older than sixteen years. Daily dose - 2-3 tablets. You need to take them one at a time, 2 or 3 rubles / day. To stop an attack acute pain two tablets should be taken at once.

The permissible upper limit of the daily dose is 6 tablets.

Citramon-Darnitsa is taken according to a similar scheme (the only difference between the drug is the age limit - these tablets are prescribed from the age of 15).

Instructions for use Citramon-Borimed

Citramon-Borimed is preferably taken immediately after meals or between meals. The drug can be used in adults and adolescents over fifteen years of age. Tablets are taken one at a time 2-3 times a day, maintaining intervals between doses of at least 6-8 hours. The highest single dose - 2 tablets, daily - 4.

As antipyretic used at temperatures exceeding 38.5 ° C (with a tendency to febrile seizures - at a temperature of more than 37.5 ° C). Single dose - 1-2 tablets.

Instructions for use Citramon Ultra

Citramon Ultra is prescribed from the age of fifteen. Daily dose - 1-3 tablets. If necessary, up to 6 tablets can be taken during the day.

Overdose

A slight overdose manifests itself in the form of nausea, dizziness, increased pallor skin, gastralgia , vomiting, ringing in the ears.

Symptoms of severe intoxication of the body: circulatory and respiratory disorders, anuria , anxiety, dizziness, nausea, headache, hyperthermia , tremor , drowsiness, restlessness, sweating, collapse , bleeding, convulsions (with pathological enhancement of tendon reflexes), .

If signs of overdose appear, the tablets should be discontinued. to prevent the absorption of the drug in the digestive canal, the patient is washed with a stomach, given enterosorbents and a saline laxative.

If the plasma concentration of salicylates in a child exceeds 300 mg / l, and in an adult - 500 mg / l, it is advisable to carry out forced alkaline diuresis. To maintain the pH of urine at the level of 7.5-8, alkalizing agents are introduced.

Carry out activities to restore the bcc and acid-base balance.

At cerebral edema IVL is prescribed with an oxygen-enriched mixture in the mode of creating PEEP (positive end-expiratory pressure). Hyperventilation should be combined with osmotic diuretics .

If there are signs of liver damage, N-acetylcysteine, which is a specific antidote, should be administered. paracetamol . The solution is used orally and injected into a vein. In total, the patient is required to enter seventeen doses: the first - 140 mg / kg, all subsequent doses - 70 mg / kg.

The most effective is the therapy started in the first ten hours after the development of intoxication. If more than 36 hours have passed, treatment is ineffective.

With an increase in the value of the prothrombin index (PTI) to 1.5-3, the use of phytomenadione (vitamin K ) at a dose of 1 to 10 mg. If the PTI is greater than 3.0, infusion of clotting factor concentrate or native plasma should be initiated.

Carry out hemodialysis antihistamines , GKS or acetazolamide (for alkalization of urine) in case of intoxication with Citramon is contraindicated.

These activities may lead to the development acidemia and enhance the toxic effect of ASA on the patient's body.

Interaction

In combination with Citramon it is strictly forbidden to prescribe with:

MAO inhibitors (when used simultaneously with caffeine these drugs can lead to a dangerous increase blood pressure );
methotrexate at a dose exceeding 15 mg / week. (this combination increases hematological toxicity methotrexate ).

Citramon also enhances toxicity barbiturates And valproic acid , effects opioid analgesics , oral hypoglycemic And sulfa drugs , digoxin And triiodothyronine .

Long-term use of painkillers for treatment headache often leads to chronic headache .

Taking Citramon may distort such indicators laboratory research as: plasma concentration of uric acid, plasma concentration heparin , plasma concentration theophylline , blood sugar level, concentration of amino acids in urine.

The drug may alter doping control tests in athletes. Complicates the diagnosis of "acute abdomen".

In case of long-term treatment with Citramon before taking a doctor's consultation is necessary.

The use of drugs containing ASA in surgical interventions(including dental surgery) increases the likelihood of occurrence/intensification of bleeding.

The drug may affect the rate of neuromuscular transmission, and therefore during the period of treatment they should refrain from administration vehicle and work with dangerous machinery.

The effect of the drug on pressure: do Citramon tablets increase or decrease blood pressure?

Headaches are a fairly common occurrence in people prone to changes in blood pressure . Therefore, questions naturally arise here: is it possible to drink medicine with high blood pressure, is the drug harmful for hypotensive patients, how are Citramon and pressure related?

Pain relief effect at headache provided primarily due to the presence of ASA and paracetamol .

The third component of the drug is caffeine - increases the flow of oxygen to the tissues, stimulates blood circulation in the brain and rise in blood pressure , thus contributing to a decrease in the intensity headache and enhancing the effects of other components of Citramon.

High doses caffeine provoke

For some viral infections (in particular, infections caused by the virus chicken pox or influenza A viruses or B-type ) there is a possibility of development acute hepatic encephalopathy (Reye's syndrome ) that requires immediate medical attention. One of the signs Reye's syndrome is prolonged vomiting.

Given the above reasons, the use of tablets in patients under the age of sixteen is contraindicated.

Because the drug has a large number of side effects, children with a headache or when a toothache is better to choose safer remedies.

Alcohol compatibility

During the period of treatment with Citramon, alcohol should be avoided, since alcohol increases the likelihood toxic action paracetamol on the liver and ASA on the gastrointestinal tract.

The use of ethyl alcohol with ASA contributes to damage to the mucosa of the digestive canal. Synergism between alcohol and ASA also results in prolonged bleeding time.

Citramon for a hangover

Citramon for a hangover is not the most advantageous option, since the use of this drug makes it possible to alleviate headache only temporarily, but does not eliminate the underlying causes feeling unwell- violation of the balance of water and electrolytes, as well as intoxication.

Headache accompanied by hangover syndrome, is associated with a violation of the venous outflow from the head, tissue edema (in particular, with swelling of the meninges ) and inhibition of the analgesic (antinociceptive) system, of which the action is serotonin And dopamine .

ASC partially unloads the membranes of the brain, caffeine stimulates metabolism in neurons and has an invigorating effect, cocoa reduces the relative deficiency intracerebral serotonin And dopamine , citric acid reduces the severity of symptoms of alcohol intoxication.

Citramon during pregnancy and lactation

Can pregnant women drink Citramon?

During pregnancy, you should avoid taking Citramon tablets, since the ASA contained in them has teratogenic influence .

The use of Citramon during pregnancy in the 1st trimester can cause splitting of the upper palate , the use of the drug in the 3rd trimester leads to a deterioration in labor activity (suppression of Pg synthesis) and closure of the ductus arteriosus at the fetus. This in turn provokes pulmonary vascular hyperplasia And pressure increase in the vessels of the small (pulmonary) circulation.

Thus, the answer to questions like “Is it possible to drink Citramon during pregnancy?” and “Can pregnant women take Citramon?” unequivocally - it is impossible.

Can Citramon be taken by a nursing mother while breastfeeding?

The use of the drug in HB is contraindicated. The active components of the tablets and their metabolites are excreted into breast milk, which increases the likelihood platelet dysfunction and the occurrence of bleeding in the child.

Citramon is a complex drug with analgesic, anti-inflammatory, antipyretic effects. The composition includes acetylsalicylic acid, paracetamol and caffeine.

Composition of Citramon:

Acetylsalicylic acid (aspirin) is a non-steroidal anti-inflammatory ingredient that provides quick deliverance from foci of infection. Additionally, one can note the ability to thin the blood, reduce capillary permeability, as well as relieve pain and local thermoregulation in the affected area.
Caffeine is an alkaloid used to stimulate the nervous system. Provides better blood flow and work of the heart muscle, reduces symptoms of fatigue, increases efficiency and activity.
Citric acid takes part in the processes cellular respiration. In addition, it serves as a stabilizing component of the drug.
Cocoa contributes to the antidepressant effect, and also stimulates metabolic processes in the body.
Additional substances: potato starch, sodium croscarmellose, magnesium stearate and low molecular weight medical polyvinylpyrrolidone.

The combination of acetylsalicylic acid and paracetamol enhances the analgesic effect of the drug. Both the analgesic and antipyretic effects of ASA and paracetamol are enhanced by the simultaneous use of these substances with caffeine.

Indications for use

What helps Citramon? According to the instructions, the drug is prescribed for pain syndrome of moderate intensity of various origins:

head,
toothache,
myalgia - muscle pain
arthralgia - pain in the muscles,
neuralgia,
painful menstruation,
fever with acute respiratory infections, influenza and other inflammatory and infectious diseases.

Does Citramon help with toothache?

Toothache is one of the indications for the use of the drug. The effectiveness of Citramon is due to the properties of its NSAIDs, non-narcotic analgesic and psychostimulant.

Reinforcing the action of each other, these components have a complex effect on the body, relieving any (including toothache) pain, especially if this pain is associated with inflammation.

With an exacerbation of chronic pulpitis, against which the temperature often rises, Citramon helps not only to relieve pain and reduce the severity of inflammation, but also has an antipyretic effect.

Instructions for use Citramon, dosage

The drug Citramon-LekT is taken according to the same scheme.

Tablets are taken during meals or after (to reduce irritating effects on the gastrointestinal tract), washed down with water.

The standard dosage of Citramon tablets according to the instructions for use is 1 tablet at least 4 hours later \ up to 3 times a day. Maximum 4 tablets per day.

With intense headache, the permissible single dose is 2 tablets, the daily dose is 8 tablets.

The drug can be used as an analgesic for no more than 5 days. As an antipyretic - no more than 3 days. The duration of the course, as well as the need to change the dosing regimen, is determined by the doctor.

Citramon forte

Applies to adults and adolescents over 16 years of age.

The standard dosage is from 2 to 3 tablets per day for 2-3 doses. There should be at least 4 hours between doses.

To stop an attack of acute pain, it is possible to take 2 tablets of Citramon forte at once.

Instructions for use sets the maximum dosage - 6 tablets per day.

Side effects

The instruction warns of the possibility of developing the following side effects when prescribing Citramon:

From the gastrointestinal tract: nausea, vomiting, epigastric pain, heartburn, erosive and ulcerative lesions digestive organs, liver dysfunction.
On the part of the blood system: decreased blood clotting, various bleeding.
From the nervous system: dizziness, headache.
From the excretory system: kidney damage.
Allergic reactions: urticaria, itching, malignant exudative erythema(Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), Reye's syndrome in children, anaphylactic shock.

With prolonged use, deafness, tinnitus, blurred vision are possible.

Contraindications

It is contraindicated to prescribe Citramon in the following cases:

full or partial combination of recurrent nasal polyposis / paranasal sinuses, bronchial asthma and intolerance to NSAIDs or ASA (including history);
hypersensitivity to the components of the tablets;
erosive and ulcerative lesions of the gastrointestinal tract in the acute phase;
stomach or intestinal bleeding;
portal hypertension;
hemophilia;
hypoprothrombinemia;
hemorrhagic diathesis;
avitaminosis K;
IHD of severe course;
severe arterial hypertension;
kidney failure;
deficiency of the cytosolic enzyme G6PD;
pregnancy (especially its first and last trimesters);
lactation;
increased excitability;
glaucoma;
dissecting aortic aneurysm;
sleep disorders;
surgical interventions accompanied by bleeding;
children's age (in children under fifteen years of age with hyperthermia against a viral infection, the likelihood of developing Reye's syndrome is high);
concomitant use of anticoagulants.

Relative contraindications are gout and existing liver pathologies.

Overdose

If these signs appear, you should immediately seek medical help.

Treatment includes gastric lavage, enterosorbents, saline laxative. Forced alkaline diuresis, alkalizing agents, measures to restore bcc and acid-base balance are shown.

Citramon analogues, price in pharmacies

If necessary, you can replace Citramon with an analogue according to therapeutic effect are the drugs:

Aquacitramon,
Acepar,
Askofen-P,
Coficil-plus,
Citrapar,
Excedrin,
Migrenol Extra.

ATX code:

Aquacitramon,
Askaff, Cofitsil-plus,
parkocet,
Citramarine.

When choosing analogues, it is important to understand that the instructions for use Citramon, price and reviews of drugs similar action do not apply. It is important to consult a doctor and not to make an independent replacement of the drug.

Price in Russian pharmacies: Citramon P tablets 10 pcs. - from 7 to 18 rubles, 20 pieces - from 33 to 42 rubles, according to 729 pharmacies.

Store in a dry place, out of the reach of children, at a temperature not exceeding 25 °C. Shelf life - 2 years. Terms of dispensing from pharmacies - without a prescription.

What do the reviews say?

Most people who take the drug leave good feedback about Citramon, calling him his savior from headaches (including migraine attacks).

Although there are also such reviews that mention harm to the liver and gastrointestinal tract, and also that with prolonged use they cause a kind of addiction (people can no longer do without Citramon for a long time and experience a constant need for it).

Based on all the available reviews, the following conclusion can be drawn - tablets should be taken taking into account the existing contraindications, as well as after comparing the expected benefits from them and the potential risks.

One or two tablets taken to relieve an attack of pain are not capable of harming the body, systematic uncontrolled reception, of course, threatens with very serious consequences.

Interaction with other drugs

Enhances the effect of indirect anticoagulants, steroid and hypoglycemic drugs.

Simultaneous use with other non-steroidal anti-inflammatory drugs and methotrexate increases the risk of side effects.

Co-administration with barbiturates, rifampicin, antiepileptic drugs and ethanol enhances the formation of hepatotoxic metabolites of paracetamol.

Citramon reduces the effectiveness of antihypertensive and anti-gout drugs that promote the excretion of uric acid from the body.

Many parents are faced with the fact that their child complains of a headache. However, not everyone knows which drugs from those used by adults are suitable for a child. One of the most common questions in a similar situation is whether Citramon can be given to children with a headache. Terms of use this drug as an anesthetic for adolescents have their own characteristics.

Citramon belongs to the group of painkillers. It is designed to relieve pain of varying degrees and has wide range indications for use.

The remedy is used when the following symptoms are detected:

headache and migraine;
toothache(temporarily exempt from pain);
discomfort during menstruation(relieves only weak spasms);
fever caused by colds, flu or acute respiratory infections (the components of the drug have an antipyretic and anti-inflammatory effect);
joint pain(Citramon allows you to remove them for a short time);
muscle pain(effectively copes with muscle pain that occurs after sprains or injuries).

You should refrain from using the medication if the headache is caused by an increase in blood pressure. People suffering hypertension, you can not use the medicine.

The composition of the drug

To the main active ingredients Citramona include:

aspirin (acetylsalicylic acid);
paracetamol;
caffeine.

Aspirin has an antipyretic effect, helps to relieve the inflammatory process, normalizes blood circulation by thinning the blood. Paracetamol relieves pain and lowers body temperature. Caffeine in combination with the above components enhances their action.

The proportions of parts of the drug may vary depending on the manufacturer.

Contraindications

Despite the fact that Citramon can be attributed to such remedies that are suitable for relieving almost any pain, it has a list of contraindications for use:

intolerance to the components of the drug;
pregnancy and lactation;
diseases of the gastrointestinal tract;
hypertonic disease;
heart and kidney failure;
glaucoma;
vitamin A deficiency;
sleep disorders;
hyperactivity and hyperexcitability;
children's age up to 15.

The instruction explains to parents how old you can give Citramon tablets to children. If the child has reached the permissible age, it is important to fully comply with the dosage and the rules for taking the tablets.

Children with headache

The list of contraindications suggests that citramon is only suitable for children over 15 years of age. It is strictly forbidden to use it to treat headaches in babies. This is due, first of all, to one of the key components of the composition - aspirin. Under its influence, changes can occur in the child's blood, leading to the development of Raynaud's syndrome.

Despite the rarity and insufficiently studied reasons for the occurrence of this anomaly, most experts believe that main reason her appearance - medical preparations containing aspirin. Since it is present in many medicines used to treat headaches and colds, parents need to know the symptoms of Raynaud's syndrome:

severe drowsiness;
decrease in reaction;
profuse vomiting;
convulsions;
fainting.

If, after taking Citramon or other aspirin-containing drugs, parents notice any of the above symptoms in a teenager, they should urgently seek medical help. Treatment of this syndrome requires constant medical supervision and hospitalization.

For the treatment of headache in a child under 15 years of age, it is recommended to use analogues of the drug designed specifically for younger children.

Mode of application

Relieve a headache with Citramon for children over 15 years old must be strictly in accordance with the instructions.
The medicine is taken orally after a meal and washed down with a small amount. clean water. To get rid of a headache, you need one tablet of Citramon. The effect should come in half an hour.

The drug is an effective remedy for relieving headaches with concomitant aches in the teeth or muscles. If the child has a headache and an elevated body temperature, it is better to use Paracetamol.

Side effects

In case it is exceeded allowable dose drug, the following side effects may occur:

nausea;
vomit;
headaches;
convulsions;
an allergic reaction in the form of rashes, itching, swelling;
blurred vision;
bleeding gums;
change in blood pressure;
cardiopalmus;
blood clotting disorder;
bleeding;
erosion of the gastric mucosa.

To avoid their appearance, it is necessary to strictly follow the instructions and refrain from taking pills if there are contraindications.

Pros and cons of using the drug for headaches

Paracetamol is one of the active substances of Citramon. Thanks to him, the blood circulation of the head is normalized and the pain goes away. Removal of symptoms is also carried out due to the caffeine contained in the preparation, which has a sedative effect. The use of Citramon in correct dosage leads to the restoration of the functioning of the nervous system, brain function and blood pressure.

Despite the numerous advantages, Citramon can also negatively affect the state of the body. The composition of the drug contains acetylsalicylic acid, under the influence of which irritation of the mucous membrane may occur. Experts do not recommend the frequent use of the drug to eliminate headaches or other pain, as this can cause allergic reaction, ulcers and bleeding disorders.

Outcome

Citramon is suitable for relieving headaches only for children over 15 years old. Babies are encouraged to choose painkillers designed specifically for their age. When using any drug for headache, you must strictly adhere to the instructions, familiarize yourself with the contraindications to the use of tablets, as well as with possible side effects.

Citramon is an affordable and familiar medicine for many that can be found in every person's home. Such a drug perfectly relieves pain and is indispensable for headaches, painful menstruation and an attack of toothache.

Many uncontrollably use the medicine without referring to the instructions of the drug, because this remedy is quite familiar and simple at first glance.

Is it possible to take Citramon for children with headaches and other manifestations of pain? Before eliminating the pain of various etiologies in a baby, you need to find out how many years you can take Citramon and under what conditions.

The composition of the medicinal product

This combined analgesic drug includes several substances, due to which the analgesic effect is achieved. Pharmacological effects Citramon is due to the following components, the list of which provides instructions for the use of the drug:

Acetylsalicylic acid - has a strong antipyretic effect, eliminates inflammation and pain caused by sepsis. The drug slightly reduces the coagulability of the blood structure and has a beneficial effect on blood circulation, especially in the area inflammatory process in body;
Caffeine - nervous system under the influence of caffeine, it becomes toned, psychomotor centers are stimulated, and the narrowed lumen of blood vessels expands. This action leads to a decrease in drowsiness, fatigue and a slight analgesic effect. Caffeine helps stimulate physical activity and tune the body to brain activity, stopping pain;
Paracetamol - acts as a highly effective analgesic, which has a gentle anti-inflammatory property and antipyretic effect.

Data active ingredients of such a non-steroidal anti-inflammatory agent guarantee quick effect and quality pain relief.

Indications for admission

Citramon is able to prevent both a small attack of pain and eliminate severe pain. Most often, the remedy is indicated for headaches, with which Citramon copes well. In particular, citramon is effective for headaches against the background of low pressure. If it is high, you should stop taking the medicine.

In what cases is citramon still relevant? Indications for admission are as follows:

Migraine and headaches - the drug well relieves a painful attack on initial stage its manifestations.
Toothache - citramon is able to reduce pain for a while, but relieve pain in fully not able to. With the help of Citramon, you can eliminate pain and improve well-being before a visit to the dentist.
Joint pain - Citramon is able to relieve pain for a short period of time. Ineffective when taken regularly, but able to provide supportive therapy for joint diseases;
Menstrual pain - the medicine will help relieve minor pain, with stronger ones, you will need to take antispasmodics;
Muscle pain - the drug well removes muscle pain after training, sprains and injuries.
These indications are a guideline in the reception medicinal product. Citramon is effective for many types of pain, including those of unknown origin. Before using the drug, you should consult with your doctor and take into account all contraindications for taking Citramon.

Side effects from taking the medicine

Despite the availability of the drug in pharmacies, side effects the drugs are pretty serious. They can manifest themselves with individual intolerance to Citramon, as well as if the recommended dose of the drug is exceeded and the regimen is violated. Side effects of the drug include:

the manifestation of nausea or vomiting, which may occur singly or regularly with repeated administration of citramon;
pathology of the functioning of the kidneys;
blurred vision;
problems in the liver;
dizziness and strong pain if the drug was taken at elevated pressure in the patient;
decrease in blood clotting, which can lead to heavy bleeding, which can be found when going to the toilet;
the appearance of pronounced noise in the ears;
allergy in the form of urticaria, severe itching, rash or anaphylactic shock with intolerance to a component or compound of the components of the agent;
the occurrence of tachycardia;
the appearance of erosions on the mucous surface of the stomach, which can cause the formation peptic ulcer gastrointestinal tract;
increase in pressure;
the appearance of edema.

Before taking citramone, you should consult with a specialist who will select correct scheme medication and help to avoid unwanted side effects of the drug on the body.

Contraindications to the use of Citramon

Before you start taking the drug, you should familiarize yourself with the contraindications for taking it. The use of citramone in such conditions is fraught with the manifestation of side effects of the drug and adverse consequences for the body. In particular, it is strictly forbidden to take Citramon when:

pregnancy;
allergic reactions;
high blood pressure;
after taking alcoholic beverages;
renal failure;
glaucoma;
sleep disturbances and disorders;
breastfeeding;
with excessive excitability of the central nervous system;
with diseases of the gastrointestinal tract, in particular - gastritis, peptic ulcer, pancreatitis.

Also, it is forbidden to take citramon to children. This is due to side effects on the background of taking the drug and the composition of the drug.

Citramon - from what age can children be taken

Is it possible to give citramon to children? Instructions for use answers this question unequivocally - citramon is prohibited for use by children under the age of fifteen. Acetylsalicylic acid in the composition medicinal product can change blood clotting and its composition, which adversely affects the baby's body and can also lead to Raynaud's disease.

Raynaud's syndrome appears quite rarely, but occurs mainly against the background of the use of aspirin. The following symptoms may indicate the disease:

drowsiness;
rave;
inhibited state;
profuse vomiting;
loss of consciousness;
passive irritability;
confusion of thoughts;
aggression;
convulsions.

As soon as such symptoms have been noticed, you should immediately consult a doctor, since Raynaud's syndrome can be treated exclusively in a hospital setting.

If the child is fifteen years old, you need to follow the rules for taking citramone. The remedy should be taken after a meal with a warm liquid. One tablet is enough for the relief of moderate pain sensations. As a rule, the first visible effect of the remedy occurs after half an hour.

Dosage of the drug

Citramon is also indispensable for acute respiratory infections. Children are shown such a drug in a dosage of one tablet. Reception should be carried out every four hours, but not more than three tablets per day.

It is important to know that a dose of eight tablets per day is critical for the body. In no case should it be exceeded. If the drug is used for antipyretic purposes, therapy should not last more than three days. If the medicine is indicated for pain relief, the course should be five days, but no more.

Other dosages and treatment regimens can only be prescribed by the attending physician. It is the specialist who will be able to correctly assess the child's condition, prescribe the dosage in accordance with the disease, the patient's condition and the symptoms of the disease. Anyway, the best option there will be an appeal to the doctor, which can prevent many adverse consequences and side effects from receiving funds.

Citramon is an effective remedy that will effectively relieve pain, prevent the development of inflammation and the development of the disease. The medicine is extremely effective for many types of pain, but it has its own nuances in application.

The drug has a number of contraindications, ignoring which can lead to serious consequences in the form of side effects. Also, citramon is contraindicated in children under 15 years of age, which is explained by the likelihood of a serious illness while taking acetylsalicylic acid. Given such subtleties in citramon therapy, many adverse effects can be avoided and only benefits can be obtained from the drug.

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