Uric acid in men. ... And the main manifestations

The materials are published for review and are not a prescription for treatment! We recommend that you contact a hematologist at your healthcare facility!

Uric acid should without fail be present in the blood, since it is it that ensures the course of a number of biochemical processes in protein metabolism. This acid is synthesized by the liver from proteins and its increase may indicate a number of serious pathologies.

Normal content uric acid in the blood is necessary for the following reasons:

• To stimulate brain activity. Through this acid, there is a direct effect on the adrenaline hormone, which leads to stimulation of the active activity of the brain.
• As a strong antioxidant, uric acid prevents the degeneration of body cells which prevents tumors from forming.

Note: chemical structure uric acid is very similar to caffeine, hence the increased activity of those people who have it above the norm at the genetic level.

Gout on the leg is one of the signs of deposits of uric acid crystals in the joints.

The human body must strictly control the content of this acid. At the same time, the norm of uric acid in the blood in women and men differs significantly. In the first case, it is 160-320 micromoles per liter, and in the second - 200-400. It should also be noted that the rate of uric acid in the blood in children is lower than in adults, ranging from 120 to 300 micromoles per liter.

Table: norm of uric acid in the blood

Why does the level of this acid rise?

If the acid content increases, then this condition is called hyperuricemia.. It happens more often in men than in women. Hyperuricemia can occur in the form of a jump under the following conditions:

• If the patient consumes too much a large number of protein foods such as eggs and meat.
• Athletes under severe stress.
• In case the patient long time is on a starvation diet.

Important! If the increase in uric acid is due to the above reasons, then this indicator returns to normal immediately after the effect of the factor that led to the increase ends.

The level of this acid also rises against the background of nephrolithiasis. There are several factors that increase its concentration:

• Violation of the liver, due to which a lot of uric acid is synthesized.

• Decreased excretory function of the kidneys.
• The patient eats a large number of foods from which uric acid is synthesized.

Important! Most often, an increase in the level of this acid occurs against the background of a violation of the functions of the liver and kidneys.

Other causes that indirectly affect the kidneys and liver:

• leukemia;
• obesity;
• long-term use of certain medications;
• decreased synthesis of B vitamins, etc.

Why is uric acid low?

A decrease in uric acid in the blood occurs in the following cases:

• Due to the use of drugs such as diuretics;
• With the development of Wilson-Konovalov's disease;
• If the patient has Fanconi syndrome;
• If the patient's diet includes an insufficient amount of nucleic acids.

Important! In most cases, a decrease in the level of uric acid indicates the presence of genetic diseases hereditary nature, which significantly complicates therapy.

Symptoms

If the patient's body is in excess of the norm of this acid, then as a result, he may manifest various diseases. In young children, it may be psoriasis or diathesis. Men have problems with joints, especially those who have reached the age of 50. Most patients have problems with thumbs on the feet, as well as elbows, shoulders, etc. In this case, pain can occur with minor movements, aggravated at night.

Important! Due to the reasons described above, a still quite young man may lose the ability to active life and even full mobility.

If urates are deposited in the urinary system, then patients suffer from pain in the groin, lower back, and also the lateral sections of the abdomen. These patients may develop cystitis involving the ureters. Stones formed often prevent normal excretion urine.

With the deposition of uric acid salts in the heart, myocardial infarction can develop in acute form. If the nervous system of the patient is affected, then chronic fatigue, insomnia and increased fatigue occur.

How to treat the pathology of the change in the norm

If any of the the above symptoms you should contact a specialist immediately. The analysis can be carried out in any clinic.

First of all, in the fight against hyperuricemia, a diet is used to reduce the amount of foods in the diet from which the liver produces uric acid. To do this, you need to exclude the use of fatty meat, liver and kidneys, lard, smoked meats, fish products, chocolate and sweets, salted and pickled vegetables, coffee and black tea, alcohol.

Advice! Experts recommend unloading every week. Such a fasting day can be aimed at the use of kefir-curd products, fruits, watermelon, etc. It is better to eat often, but in small portions (up to six times a day on average).

Table: The diet is recognized as one of the most effective methods in the fight against high lactic acid

Blood is a universal fluid. It can be used to determine the exact state of the main body systems. Before deciphering your own tests, it is worth remembering that the level of uric acid cannot be assessed without paying attention to other substances - creatinine and urea. Let's figure out what the norms of uric acid in the blood are set for men after 40 years.

Features of the analysis

During the synthesis of ribonucleic acids, purine bases are released, after the splitting of which uric acid is released into the blood. It is synthesized by the liver and without changes with the blood enters the kidneys, through which it is excreted from the body. To determine the level of uric acid in the blood is necessary for the diagnosis of:

• urolithiasis;
• gout;
• diseases of the lymphatic system;
• kidney pathologies.

To determine the level of uric acid, men conduct a biochemical study of blood serum. You need to prepare for it according to the rules:

1. The procedure is carried out in the morning, the patient must refrain from eating for 8 hours. You can only drink pure water in small quantities.
2. Two days before the biomaterial is taken, fried, smoked, spicy, fatty foods should be excluded from your diet. Do not drink during this period. alcoholic drinks.
3. The day before the analysis, reduce the amount of fish, tea and coffee in the diet. During this period, do not eat meat, offal, legumes. This limitation is due to the fact that these products are high in purines, which can skew the result.
4. The analysis is carried out before treatment or after its completion after 2 weeks, if at the time of blood sampling you are being treated for any disease, taking drugs for health reasons, you must indicate the names of the drugs. When deciphering the tests, the doctor must take into account the effect of medications on blood components.
5. Biochemical analysis should not be carried out after radiography, ultrasound, fluorography, physiotherapy. These activities can change the composition of the blood.

Only if these rules are observed, it is possible to obtain reliable information about the level of uric acid and other blood components that are decay products.

Normal performance

Medical scientists have created a table that collects the limits of uric acid levels for different ages:

Despite the fact that the standards are developed without regard to gender, most doctors examine uric acid in men, as they are prone to gouty arthritis. In this disease, uric acid salts are deposited in the joints. After 40 years in men, the predisposition to hyperuricemia is up to 25%. It is believed that at the level of this substance from 250 to 400 µmol / l, a forty-year-old man is out of the risk zone.

Reasons for deviations

The output of uric acid indicators beyond the normal range upwards may be due to primary and secondary causes. The primary ones are individual characteristics human, congenital genetic abnormalities and diseases:

• Lesch-Nyhan syndrome;
• gout;
• congenital increase in the synthesis of phosphoribosyl pyrophosphate;
• Kelly-Sigmiller syndrome.

Secondary causes are acquired diseases that affect the breakdown of purines. These reasons include:

• hemolytic anemia;
• acute or chronic renal failure;
• psoriasis;
• intoxication with salts of heavy metals, lead compounds;
• chemotherapy;
• oncology of the blood and brain, which occurs with myeloproliferation syndrome;
• protein diets;
• alcoholism;
• exhaustion due to malnutrition, unbalanced diet, eating disorders.

Pharmacological drugs can increase the level of uric acid:

• methyldopa;
• vitamin B3;
• caffeine;
• aspirin;
• theophylline;
• levodopa;
• diuretics;
• vitamin C.

In some cases, such as diabetes or burns, uric acid levels can be lowered, but doctors usually know the reason for an incorrect result even before analysis.

To confirm hyperuricemia in men, a study of daily urine is performed. After confirming the diagnosis, treatment begins, which may include taking medications:

• to enhance renal secretion;
• based on allopurinol, reducing the amount of purine excretion.

The basis of treatment is a diet that is selected individually for a man, based on the cause of hyperuricemia. Changing the diet is aimed at normalizing metabolism. With it, foods that can increase the formation of uric acid are excluded from the menu: chocolate, tea and coffee, canned food, smoked meats, fatty meats, offal, carbonated drinks. The number of eggs is limited.

Additionally, the patient may be advised folk remedies, for example, decoctions of lingonberry leaves, currants, birch buds, nettles. They do not notice the medicines that are required to be taken. Complex treatment controlled by laboratory testing of urine and blood.

To diagnose diseases, doctors prescribe patients to undergo various studies, including donating blood for the volume of uric acid contained in it. Uric acid (food substances) in men determines the state of proteins - an important building material.

Uric acid indicators do not meet the requirements if the following diseases are diagnosed:

• the formation of stones;
• kidney dysfunction is present;
• there is a suspicion of gout;
• concerned about diseases affecting the lymphatic system.

In order for the nutritional substances in a man to be shown in real values, it is important to pass the analysis correctly. Consider these rules:

1. The analysis is taken on an empty stomach, you can’t eat for 7-8 hours, you can drink water.
2. Two days before the scheduled analysis, you can not consume fatty, fried foods, alcoholic beverages.
3. One day before blood sampling, limit the amount of tea, coffee and eaten fish products. Give up meat dishes, offal, legumes due to the high composition of purines.
4. Conduct an analysis before the start of the therapeutic course and after it, in a couple of weeks.
5. It is not allowed to donate blood immediately after passing fluorography, ultrasound, and undergoing physiotherapy procedures. Indicators may be incorrect and untrue.

Standards for uric acid in the blood in men over the age of 60 years

Deviations are called lower rates and elevated, both require a detailed study of the specific medical history and prescription of therapy.

Why deviations from the norm appear

If the amount of nutrients in the blood serum of a man after 60 years of age exceeds the stated standards, the doctor makes a diagnosis of hyperuricemia. If the disease is primary, the cause is a congenital disorder in the breakdown of purine enzymes, which causes the active formation of an increased content of uric acid. Causes of the disease:

• gout;
• Lesch-Nyhan or Kelly-Sigmiller syndrome;
• genetic failure of FRPP synthesis.

Secondary hyperuricemia can be caused by acquired ailments, for example, improper metabolism, excessive consumption of purine-rich foods. Provoke disease:

• psoriasis;
• anemia of hemolytic format;
• renal failure, occurring in acute or chronic form;
• lead poisoning;
• oncology diagnosed in the blood and bone marrow;
• a consequence of chemotherapy;
• alcohol abuse;
• malnutrition;
• eating large amounts of protein foods.

The reduced value of nutrients occurs with such ailments:

• congenital course of xanthinuria;
• a side effect after taking Allopurinol, which inhibits the formation of purines;
• diabetes;
• burns;
• the presence of a cancerous neoplasm;
• AIDS.

You need to be careful when taking estrogens, Warfarin, Mannitol, Clofibrate - these active substances significantly reduce serum uric acid levels.

How to bring uric acid back to normal

If uric acid is outside the generally accepted norm, a man after 60 years of age is prescribed one of the following treatments:

1. Taking drugs that increase renal secretion. As a result, nutrients leave the patient's body, and their concentration becomes normal.
2. Allopurinol - helps to inhibit the formation of uric acid.

The complex must adhere to diet food. Diet does not mean starve, on the contrary, it is reasonable approach to the preparation of a daily balanced menu. The goal is to achieve the correct metabolism.

How can this be done? Take note of the recommendations of doctors:

1. The formation of uric acid is facilitated by fatty meat-rich dishes, broths, offal, canned food.
2. Avoid pickles and alcohol.
3. For dessert, you can eat everything except chocolate. Minimize the amount of sweets and confectionery eaten.
4. Instead of tea, coffee and carbonated drinks, lean on clean water.

What should be included in the diet?

1. Lean poultry meat.
2. Dairy dishes.
3. Eggs (1-2 pieces per day).
4. Vegetable oil.
5. Fruits vegetables.
6. Vitamin natural juices and compotes, fruit drinks, kissels.

A large amount of liquid helps the rapid outflow of nutrients. The daily dose should be from 2 to 3 liters. If the diet is ineffective and the uric acid levels in a man after 60 years of age cannot be normalized, the doctor prescribes medications:

• Allopurinol;
• Colchicine, saving from complications;
• means for the rapid excretion of urine.

How long to take each of the drugs, the attending physician decides. It does not hurt to add decoctions made from currant leaves, lingonberries, birch buds, nettles, and highlander grass to pharmaceutical medicines.

If a man has been diagnosed with increased or decreased uric acid, it is advisable to routinely donate blood for examination every six months.

Performs important functions in the body. However, if the indicators of the substance in the blood are higher than normal, it is necessary to urgently begin treatment, since this condition is characterized not only by a deterioration in the patient's well-being, but also by the development of complications.

To normalize the level of acid, various medications and recipes traditional medicine. It is also mandatory for treatment to comply with general principles right image life, which contribute to the reduction of substances in the body.

Uric acid - what is it, its normal level

Uric acid is a substance that is produced as a result of the metabolic process during the breakdown of purines. digestive system. A substance is formed in It usually dissolves in the blood and enters the kidneys. In this case, uric acid is excreted during urination.

Among the important functions of this substance in the body are:

• Antioxidant action, which is to protect cells from free radicals.
• Activation of epinephrine and norepinephrine, which affects normal functioning nervous system.
• Prevention of the development of cancer cells.
• Excretion of carbon dioxide from the body with urine.

The amount of a substance in the blood depends on the age criterion, as well as on the gender of the person. The following indicators are normal levels:

• In men - from 210 to 420 micromoles per liter
• In women - from 150 to 350
• Children up to one month - up to 311
• Under the age of one year - from 90 to 372
• From one to fourteen years - from 120 to 320

The highest rate of acid at the norm is observed in male body. This is due to the fact that when performing physical work, the body of a man needs frequent replenishment of the body with proteins.

To obtain accurate and reliable results, you need to know how to properly prepare for the study. Experts recommend donating blood on an empty stomach. It is also important to exclude foods that contain a huge amount of proteins and alcoholic beverages a few days before the analysis. If a person takes any medications, this factor must be told to the doctor. It is advisable for people after forty-five years to undergo diagnostics annually.

Blood for research is taken from a vein. Uric acid is determined by blood serum. Usually, the results of the analysis can be obtained at the clinic the next day.

The main factors of increased level

Hyperuricemia - high levels of uric acid in the blood

Physiological and pathological factors influence the increase in the substance in the blood. The two main causes of higher than normal urinary levels are considered to be a violation of the production of a substance in the liver and improper excretion of it by the kidneys.

Uric acid rises in the following cases:

• Heavy physical exercise.
• Starvation long time.
• Protein diet.
• Long-term use of certain medications.
• Eating foods that are high in protein.
• Alcohol abuse.

An increase in the substance is determined in the blood in such diseases:

• Pathologies in which the excretion of a substance in the urine is difficult.
• Diseases endocrine system(, acidosis).
• Hereditary diseases (Lesch-Nyhan syndrome, Hodgkin's disease).
• Psoriasis and other pathological conditions of the skin.
• Pathology of the liver (,).
• Infectious diseases(scarlet fever, tuberculosis, pneumonia).
• Hypovitaminosis (mainly vitamin B12 deficiency).
• Oncological diseases (most often leukemia, lymphoma).
• Allergic reactions.
• Arterial hypertension.
• High levels in the body and lipoproteins
• Hyperuricemia is considered important sign for diagnosing gout.
• Uric acid can rise due to obesity and complications of pregnancy, for example, with toxicosis.

Signs of high levels of a substance in the blood

The following signs may indicate an increased content of uric acid in the body:

• Bad feeling.
• Back pain.
• High .
• Soreness in the joints.
• Indigestion.
• General weakness.

One of the frequent signs of hyperuricemia in adults is the occurrence of tartar and decreased performance. With an increase in the substance in the body, pain during urination is possible.

In children, hyperuricemia may be accompanied by enuresis, frequent pain in the abdomen, neurological disorders. Diathesis spots are often observed in small patients.

Treatment Methods

First of all, treatment should be directed to the underlying disease that provoked the high level of uric acid. Therefore, only a specialist can prescribe medicines. If uric acid is elevated due to physiological reasons, then this condition does not need special treatment. Over time, the level will normalize on its own.

Usually, in order to lower uric acid in the body, the following groups of drugs are used:

• Drugs that remove uric acid from the blood. Probenecid is one of them.
• Medications that reduce the production of uric acid. Usually prescribed when complications begin to appear advanced level substances. These drugs include Colchicine, Allopurinol, Benzobromarone.
• Drugs that transfer a substance into the blood from the tissues and affect the intensity of its excretion in the urine. Effective from this group of drugs is Tsinkhoven.
• With hyperuricemia, diuretics such as Lasix, Mannitol, Furosemide, Sulfinpyrazole are often prescribed.

Other methods of lowering substances in the blood are:

• Plentiful drink. Drinking liquid contributes, as a result of which excess uric acid is excreted from the body. It is recommended to drink nine to fifteen glasses of plain water per day.
• Proper nutrition. Avoid foods that contain purines from your diet. Therefore, it is recommended to refuse meat by-products, anchovies, beer, confectionery, white bread, smoked meats, legumes, drinks containing fructose. It is also important to limit your salt intake. It is advisable to eat fresh fruits and vegetables, dairy products. Portions for hyperuricemia should be small, it is better to eat up to five times a day.
• Weight loss. It is recommended to increase physical activity, adhere to a certain diet. However, fasting must be avoided.

Useful video - Uric acid in the blood: causes and treatment

There are also recipes in alternative medicine that help normalize uric acid. Among such remedies, the most effective is the use of decoctions and tinctures from such medicinal plants inside:

• Sabelnik.
• Lingonberry (leaves).
• Collection of calendula chamomile and sage.
• Birch leaves.
• Lemon and garlic.

As an auxiliary medicine for high uric acid, it is recommended to take nettle juice. When using folk remedies, it is important to remember that they are not a panacea, but are used as an auxiliary method to the main treatment.

If uric acid is elevated in the body for a long time, this can lead to the development of serious conditions.

Often a high level of a substance in the blood leads to the occurrence of the following pathologies:

• Gout.
• Formation of stones in the kidneys and urinary tract.
• body intoxication.
• Ischemic disease.
• Myocardial infarction.
• Angina.
• Chronic arthritis.

Often, with a high content of uric acid in the body, lesions of the nervous system occur, against which migraines, sleep disorders, decreased vision, attacks of aggression occur.

The development of complications depends on the localization of the formation of sodium urates by uric acid. If crystals appear in the kidneys, diseases of this organ occur. With the deposition of urate in the joints, gout begins to progress and.

A by-product of the metabolism of purine bases, which is in the blood plasma in the form of a sodium base, is uric acid or stone, the content of which in the blood, urine is one of the diagnostic markers, a symptom inflammatory processes, crystal deposits, disorders of purine metabolism. Both high and low rates indicate pathological mechanisms in the body.

What is uric acid

Organic matter formed as a by-product of purine metabolism during metabolism is called uric (stone) acid. Its normal content does not harm the tissues of the body, but at an increased concentration in the blood, it begins to accumulate in cartilage and joints, causing their active inflammation. Salt crystals contribute to an increased risk of developing acute inflammation. An elevated level of a substance occurs when the urinary system does not function well (with kidney stones). An increase in uric acid in the blood is called hyperuricemia.

Formula

Organic matter, belongs to the class of dibasic acids, has the form of white crystals. When metabolized in the human body, it forms acidic and medium salts called urates. It exists in two forms - lactam and lictim. It was first discovered by the Swedish pharmacist-chemist Scheele in 1776, synthesized artificial method Gorbachevsky in 1882

Blood uric acid test

Measurement of the content of this metabolite is not a standard analysis, it is prescribed by a doctor in case of suspicion of diseases that disrupt metabolism or the normal functioning of the kidneys. To study the acid content in plasma, blood is taken from a vein in the morning on an empty stomach, in an amount of 5-10 ml. Biochemical analysis in the laboratory is done for about a day using special sera, enzymes.

What does uric acid show in a blood test?

The content of the metabolite shows the state of all the main body systems, the type and quality of nutrition, the degree of functioning of metabolism. Elevated levels of uric acid means a malfunction of the kidneys, liver, or metabolism. Poor nutrition, an increase or decrease in the content of fructose in the diet immediately affects the amount of acid in the blood plasma. Excessive synthesis of a substance leads to the deposition of excess salts, disruption of the normal metabolism of nucleic acids.

Deciphering a blood test

The number of metabolites of purine bases in the biochemical analysis of blood of the old sample is indicated by the abbreviation "ur. acids", in new electronic, clinical computer programs - the Latin abbreviation "UA". The content of a substance is expressed in kilomoles per liter of blood plasma, which refers to the number of molecules contained in the blood.

Norm

If the analysis shows that the content of the metabolite is on the border of the upper or lower norm, the attending physician must prescribe additional laboratory tests, instrumental research to collect the patient's medical history in more detail. The extreme indicator may indicate a developing pathological mechanism, early diagnosis which will avoid many symptoms and complications (kidney disease). The physiological norm of uric acid in the blood is:

• in children under 14 years old - 120 - 320 µmol / l;
• in adult women - 150 - 350 µmol / l;
• in adult men - 210 - 420 µmol / l.

Uric acid in the blood is elevated

In therapy, two types of hyperuricemia are distinguished: primary and secondary. An idiopathic or primary disease is a disease that has arisen as a result of the inheritance of a mutated gene that is responsible for the normal process of splitting purines. Diagnosed in children in the first year of life, is rare. Secondary hyperuricemia occurs for a number of reasons: organ pathology (liver disease), malnutrition. Often occurs in the elderly, in conjunction with arthritis, patients with gout.

excess symptoms

With a slight increase in the level of the metabolite, the patient's well-being does not change. Significant damage to health is caused by constantly high or recurring hyperuricemia. Clinical picture, its intensity depends on the age of the patient:

1. Children up to 14-15 years of age have permanent signs skin problems: rash, peeling, itching, development of psoriasis. Affects physical development children under three years of age.
2. Men over 50-55 years old suffer from pain in the joints during movement and at rest, swelling of the limbs, gout attacks.
3. Middle-aged men and women suffer from severe itching, weeping rash on the body, pain.
4. In women, the microflora of the vagina suffers, attacks of exacerbation of candidiasis become more frequent. Hyperuricemia leads to prolonged menstrual irregularities.

Causes

Hyperuricemia can be caused by two main causes of an increase in the concentration of urinary bases: a violation of their excretion by the kidneys and an increased breakdown of purines. In addition, some drugs may cause increased concentration metabolites in the exchange of purines, for example, diuretics. The high content can be caused by the formation of their depot - the accumulation of crystalline salt.

Reasons for depositing can be:

1. Diseases of the urinary system. When the kidneys do not cope with the filtering function, metabolites settle, are deposited in the tissues of the joints, and gout develops.
2. Endocrine diseases. Diabetes, the tendency to acidosis cause intense breakdown of purines, and, as a result, a high concentration of final metabolites that do not have time to be excreted by the kidneys.
3. Improper nutrition, starvation, an excess of meat in food, dairy products.

Uric acid is low

A decrease in the concentration of a metabolite is diagnosed by a doctor when two or more biochemical analysis blood plasma showed the concentration of acid below the lower limit of the norm. The condition is due to a decrease in the production of a metabolite, an increase in excretion from the body along with urine, bile, acid breakdown under the influence of the uricase enzyme, which is a component of some drugs to combat gout.

Causes

Among the reasons that cause a decrease in the number of purine metabolites, the following are distinguished:

• hereditary deficiency of xanthine oxidase - a disease in which xanthine is not converted to the final metabolite, due to the lack of enzymes;
• acquired xanthine oxidase deficiency;
• low purine or low protein diet;
• increased excretion of a substance in the urine;
• Fanconi syndrome - acid reabsorption in the tubules of the kidneys is maximally reduced;
• familial renal hypouricemia hereditary disease caused by a mutation of the genes responsible for the reverse absorption of purine metabolites;
• an increase in extracellular fluid volume.

Treatment

Therapy for the state of hypouricemia consists in diagnosing the disease that caused the decrease in the content of the metabolite. If the disease is hereditary, incurable, the doctor prescribes drugs that stop the symptoms of the disease. Mandatory basis of therapy is diet, lifestyle changes. The patient, to control the condition, is assigned an analysis every week, then every month.

How to lower the level of uric acid in the blood

To reduce the concentration of the metabolite, drug therapy is used: diuretics, enzyme preparations, drugs that reduce the absorption of a substance renal tubules. For background treatment to reduce the content by-products, nutritional adjustment is required - a decrease in the consumption of food containing a large amount of purines, their bases. A diet with elevated uric acid in women must necessarily include animal fats - this prevents an imbalance of sex hormones.

Medical therapy

The following medications are used to treat low or high acid levels:

1. Allopurinol. Medicine, produced in the form of tablets, 30 or 50 pcs. packaged. Hypouricemic, anti-gout agent. Prevents the synthesis of the enzyme xanthine oxidase, which enhances the production of purine bases to the final metabolites, metabolic products. From positive characteristics it is possible to allocate a cumulative effect, a soft gradual effect. The disadvantage of the drug is an aggressive effect on cardiovascular system.
2. Etamide. It is used to lower the concentration of acid by reducing its reabsorption by the renal tubules. It has a tablet form of release, is contraindicated in children under 14 years of age, patients with kidney failure helps to remove excess salts. A positive feature of the drug is the effect of reducing the synthesis of purines, reduces the content of sodium salts, negative - strong impact on the kidneys, which can lead to organ failure.
3. Sulfinpyrazone. Increases the excretion of acid by the kidneys with the help of increased diuresis. Release form - drops or tablets. Drops are prescribed mainly for children. The advantages of using the drug are a mild but strong effect. Cons - removes potassium and sodium from the body.
4. Benzbromanone. Prevents reabsorption of the metabolite back into the bloodstream. Available in the form of capsules, tablets. Contraindicated for people with kidney disease. The advantages of using the drug are the cumulative effect of therapy, the disadvantages are that it contributes to the retention of salts and water in the interstitial fluid.

Diet

When a patient is diagnosed with changes normal level acids, he is prescribed special diet. Adjusting nutrition will not cure the disease, but will help bring the level of the metabolite into the normal range. The list of prohibited and permitted products depends on whether the content of the substance is increased or decreased. At high level forbidden to use protein food, fructose. If the content of the substance is lowered, then these foods, on the contrary, are mandatory for consumption.

Treatment with folk remedies

To reduce the level of acid, to increase its excretion by the kidneys, it is recommended to use infusions, decoctions of birch leaves, lingonberries, angelica root, bay leaf. Herbs contribute to the excretion of acid by the kidneys, reducing its content. Prepare a drink from the infusion as follows:

• two tablespoons of dry herbs should be added to a glass of boiling water;
• cover with a lid for 2-3 hours;
• use a tablespoon 2 times a day before meals.

Herbs, roots are considered potent means to remove salts. To combat inflammation of the joints, remove the urinary base, treat gout, you can prepare a home-made ointment from burdock root. Burdock has an excellent anti-inflammatory effect, enhances excretion harmful substances, there is a decrease in uric acid in the blood, acidity of urine. If the acid is elevated, with regular use, patients note a decrease pain syndrome, decrease in swelling of the joint. So, to make an ointment from the burdock root should be as follows:

• take 4-5 units of ground burdock root, petroleum jelly, a tablespoon of alcohol;
• mix until the consistency of thick sour cream;
• apply to a sore joint;
• wrap in a towel or diaper;
• leave overnight.

How to increase uric acid

After detecting a low concentration of a substance, the doctor should prescribe additional research to identify a disease or condition that has caused a decrease in the amount of the end metabolite of purines. Prescribe medications, a special diet with a high protein content, vitamins, and reduce salt intake. In order to eliminate the decrease in the acid content in the blood, it is necessary to eliminate the cause of its occurrence. Helps reduce the risk of hyporinumia pure water.

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