Tantum Verde description. Topical solution tantum verde

Date: 04.11.2019

Instructions for use Tantum Verde indicates that it is a local remedy with anti-inflammatory activity, antiseptic and analgesic effects. The active substance of the drug, benzidamine hydrochloride (an imidazole derivative), provides such a therapeutic effect. Tantum Verde belongs to the group of NSAIDs (non-steroidal anti-inflammatory drugs) and is used in dentistry and ENT practice.

Spray and tablets Tantum Verde - description of the drug

The mechanism of action of Tantum Verde is aimed at blocking the synthesis of prostagladins - the main mediators of inflammation and stabilization of cell membranes. The active substance of the drug provides analgesic and and exhibits pronounced antiseptic properties against a wide range of pathogenic microorganisms.

The antibacterial effect is achieved due to the fact that benzidamine penetrates very quickly through microbial membranes, disrupts the structure of the microorganism, the course of metabolic processes and causes the death of the microbial cell.

The drug also exhibits a pronounced antifungicidal effect with respect to Candida genus fungi due to the fact that it modifies the walls of fungal cells and prevents their further reproduction. The active component is characterized by good absorption, is quickly absorbed and penetrates deeply into inflamed tissues, without provoking pronounced adverse reactions. It is excreted from the body by the kidneys, part of the decay products is removed through the intestines.

Forms of medicine

Anti-inflammatory drug is available in several dosage forms:

Tantum Verde tablets are green, translucent, square in shape, with a minty smell and sour lemon flavor. Tablets are intended for resorption in the oral cavity. Each of them contains 3 mg of active substance and a number of auxiliary components. Tablets are packed in paraffin paper and aluminum foil and 10 pieces are placed in a cardboard box.
Tantum Verde spray is a clear liquid with a mint aroma. Available in 30ml plastic bottles equipped with a spray device. 1 dose of the drug contains 255 μg of benzidamine + excipients. One spray bottle is designed for 176 doses.
Tantum Verde solution is a translucent liquid of a greenish color with a characteristic menthol odor. 100 ml of the solution (0.15%) contains 150 mg of the active substance - benzidamine. The solution is produced in glass bottles with a volume of 120 ml, complete with a graduated glass designed for dosage of the solution.

When is Tantum Verde appointed?

Indications for use of the drug are diseases of ENT - organs and oral cavity of various etiologies:

inflammatory diseases of the throat and pharynx - tonsillitis, pharyngitis,;
lesions of the oral cavity and gums of an inflammatory nature (gingivitis, stomatitis, periodontal disease, glossitis);
conditions after tooth extraction or dental procedures;
conditions after surgical interventions to remove adenoids or traumatic injuries of the jaw.

Tantum Verde successfully copes with the calculous inflammatory process in the salivary glands and candidiasis (as part of a comprehensive treatment). In order to anesthetize and stop the inflammatory process, it is also used for other inflammatory and infectious diseases. Tantum Verde with angina helps to reduce inflammatory manifestations, relieve irritation, soreness and pain in the throat, stop the reproduction of pathogenic microflora.

Instructions for use

Instructions for use of the drug give detailed recommendations for use, taking into account the form of the drug:

Tablets (lozenges) should be kept in the oral cavity for as long as possible, until complete resorption. The daily dose is 3-4 pieces.

Spray for adult patients is recommended to be applied every 1.5 to 3 hours, at a time producing from 4 to 8 injections. Each injection is equal to 1 dose of the drug. Tantum Verde for children is used with the same frequency as in adults, but in a lower dosage:

for the smallest patients (from 3 to 6 years) - from 1 to 4 doses (injections)
for children from 6 to 14 years - 4 doses.

Solution. The dosage of the Tantum Verde solution is carried out using a special measuring cup. It is recommended to use 15 ml of the drug 2-3 times a day. Doctors recommend rinsing with a solution to adult patients and clarify that the procedure should be done no more than once every half hour.

If there is a burning sensation in the mouth when using the solution, it is recommended to dilute it with water in a ratio of 1: 1. Spray the spray with care, avoiding contact with eyes. If this happens, immediately rinse your eyes with plenty of water.

Analogs

Among the analogues of Tantum Verde, with an identical therapeutic effect, the following drugs can be named:

Ingalipt;
Hexoral;
Sebidine;
Grammidine Neo.

With intolerance to the components of Tantum Verde, the doctor can always choose a replacement from this list of drugs.

Price

Tantum Verde can be bought at the pharmacy freely, without a doctor’s prescription. The price of the drug depends on the form of release, the region of sale and the development of pharmacy chains. On average, the cost of different forms of the drug is as follows:

Spray Tantum Verde - from 260 rubles;
Tantum Verde tablets (10 pcs.) - from 200 rubles
Rinse solution (120ml) - from 320 rubles.

Tantum Verde is a new generation of nonsteroids and is an effective anti-inflammatory drug indicated for topical application. A derivative of indosols in the form of benzidamine hydrochloride is used as the main active ingredient.

In this article we will consider why doctors prescribe Tantum Verde, including instructions for use, analogues and prices of this drug in pharmacies. REAL REVIEWS of people who have already used Tantum Verde can be read in the comments.

Composition and form of release

Spray Tantum Verde: a clear liquid with a peculiar mint smell. Available in bottles of polyethylene with a pressure device with a cannula and a pump. In a pack of cardboard 1 bottle of 30 ml, designed for 176 doses, and instructions from the manufacturer.

Composition of the spray: in 1 dose - 255 μg of benzidamine hydrochloride. Additional components: N bicarbonate, menthol flavoring, methyl parahydroxybenzoate, glycerol, water, saccharin, ethanol 96%.

Clinical and pharmacological group: NSAIDs for topical use in ENT practice and dentistry.

What helps Tantum Verde?

Designed for the treatment of infectious and inflammatory diseases of the oral cavity and pharynx:

glossitis, gingivitis, stomatitis (including disorders after chemo- and radiation therapy),
pharyngitis, laryngitis, tonsillitis, tonsillitis,
calculous inflammation of the salivary glands,
periodontal disease
candidiasis (as part of complex therapy),
after treatment or extirpation of teeth,
after injuries or surgical interventions (including jaw fractures, tonsillectomy, etc.).

Despite the fact that this drug practically does not show side effects and has minimal contraindications, you should not self-medicate and sprinkle or gargle yourself, this may be fraught with the fact that therapeutic effects do not occur, and the use of the medicine will bring disappointment.

pharmachologic effect

Tantum Verde is a non-steroidal anti-inflammatory drug for topical application. The active substance is benzidamine hydrochloride, a derivative of indosols.

When used locally, it has anti-inflammatory and analgesic properties due to the suppression of prostaglandin synthesis and stabilization of cell membranes.

It is absorbed through the mucous membranes well, accumulates in inflamed tissues. Eliminated by the digestive system (with feces) and the kidneys (with urine).

Instructions for use

For those who use Tantum Verde, the instructions for use report that the dosage of the drug depends on the form of release.

Resorption tablets are prescribed 1 tab. 3-4 times / day.
Adults (including the elderly) are prescribed 4-8 doses of the spray every 1.5-3 hours. Children aged 6-12 years - 4 doses; for children under 6 years of age, the dose is determined at the rate of 1 dose for every 4 kg of body weight (maximum 4 doses) every 1.5-3 hours.
A topical solution is used in 1 tablespoon (15 ml) of a mouthwash or throat every 1.5-3 hours to relieve pain. After rinsing, the solution must be spit out.

When using Tantum Verde in the form of a spray, caution is advised to prevent contact with the drug in the eyes.

Contraindications

The medication is not used in the following conditions and existing diseases:

Allergic reactions to components;
Genetic manifestations due to impaired metabolism of phenylalanine;
Undiluted solution for children under 12 years old;
Asthma;
Tablets for resorption to a child up to 2 years;
Exacerbation of ulcerative manifestations of the stomach;
Obstruction of the lungs.

Side effects

The use of Tantum Verde is accompanied in some cases by such consequences as:

burning in the mouth;
numbness;
dry mouth
laryngospasm;
allergic responses;
skin rashes.

If these symptoms are found, after taking the medicine, you should stop using it and consult with your doctor.

Analogs Tantum Verde

Currently, the most effective and most popular synonyms for the above drug are:

lozenges: Sage and Novoscept forte;
spray for local use: Novoscept Forte, Proposol N and Proposol;
solution for local use: Yoks, Poliminerol, Maraslavin and Salvin;
dental drops: Denta, Dentaguttal and Dentaplus;
lozenges: Sage;
capsules: Piaxledin 300;
dental gel: Holisal, Dologel ST, Dicloran Denta, Kalgel, Vitadent and Dentinoks.

Attention: the use of analogues should be agreed with the attending physician.

Prices

The average price of TANTUM VERDE, spray in pharmacies (Moscow) 260 rubles.

Pharmacy Vacation Terms

The drug is approved for use as a means of OTC.

NSAIDs from the group of indosols for topical use in ENT practice and in dentistry. It has anti-inflammatory and local analgesic effects. The mechanism of action of the drug is associated with stabilization of cell membranes and inhibition of prostaglandin synthesis. When applied topically, the drug is well absorbed through the mucous membranes and penetrates into the inflamed tissue.

Indications for use of the drug Tantum Verde

Inflammatory diseases of the oral cavity and ENT organs: gingivitis, glossitis, stomatitis (including after radiation and chemotherapy), tonsillitis, pharyngitis, laryngitis, tonsillitis, candidiasis (as part of combination therapy), post-tonsillectomy; calculous inflammation of the salivary glands, conditions after treatment and tooth extraction, periodontal disease. In infectious and inflammatory diseases - as part of combination therapy.

Contraindications to the use of the drug Tantum Verde

The drug Tantum Verde does not need to be used if the patient has ulcerative pathology, bronchial asthma, heart failure, fku (for children under 12 years old). The medication is strictly contraindicated in children under 12 years of age (for tablets and solution for local use) and if the patient has hypersensitivity to the drug or its components.

The use of the drug Tantum Verde

A solution for rinsing the throat or mouth - 15 ml (1 tablespoon) every 1.5-3 hours (can not be swallowed).
   Tablets - 3 mg 3-4 times a day (kept in the mouth until completely resorbed).
   Aerosol (indicated for the elderly or sick in the postoperative period with the inability to rinse the mouth) every 1.5-2 hours - for adults and elderly patients - 4-8 doses, children 6-12 years old - 4 doses, children under 6 years old - 1 dose for every 4 kg of body weight (maximum - 4 doses).
   Vaginal washing 1-2 times a day: the powder (1 sachet) is dissolved in 500 ml of water (the solution must be warm) and 140 ml are used for single douching, the procedure is carried out lying down, the liquid should remain in the vagina for several minutes.
   The gel is applied to the affected area of \u200b\u200bthe skin 2-3 times a day and gently rubbed until completely absorbed.

Side effects of the drug Tantum Verde

The most common side effects when using the Tantum Verde drug include: nausea, vomiting, diarrhea, palpitations, headache, dizziness, drowsiness, tinnitus, increased sweating, confusion.
With prolonged use of the drug Tantum Verde, the patient may have gastrointestinal bleeding, bleeding from the gums, anemia, a decrease in the number of platelets.
Rarely: skin rash, itching, Quincke's edema, urticaria. With topical use of the drug Tantum Verde, the patient may show a feeling of numbness, burning, dry mouth. In the presence of the above-mentioned undesirable effects, you should consult a doctor.

Special instructions for the use of the drug Tantum Verde

Avoid contact with the spray. If a burning sensation occurs when using the solution, the solution should be diluted with water 2 times by adjusting the water level to risks in a graduated glass.

List of pharmacies where you can buy Tantum Verde:

St. Petersburg

Tantum Verde is a drug with a local anesthetic, analgesic and anti-inflammatory effect.

Release form and composition

Tantum Verde is available in the following dosage forms:

Lozenges (10 pcs. Per pack, each of which is wrapped in waxed paper and placed in a wrapper made of aluminum two-layer foil; 2 packs in a cardboard box);
A solution for topical administration of 0.15% (120 ml in bottles; 1 bottle in a cardboard bundle complete with a measuring cup);
Topical spray dosage 0.255 mg / dose (30 ml each in bottles equipped with a pressure device with a folding cannula and pump, 1 bottle in a cardboard box).

The composition of 1 tablet for resorption includes:

Active substance: benzidamine hydrochloride - 3 mg;
Auxiliary components: isomaltose, aspartame, racementol, citric acid monohydrate, mint and lemon flavor, indigo carmine dye (E132), quinoline yellow dye (E104).

The composition of 100 ml of solution for topical use includes:

Auxiliary components: 96% ethanol, glycerol (glycerin), sodium bicarbonate, methyl parahydroxybenzoate, saccharin, menthol flavoring, polysorbate 20, 70% quinoline yellow dye (E104), 85% blue patented dye (E131), purified water.

The composition of 100 ml of topical spray dosed includes:

Active substance: benzidamine hydrochloride - 150 mg;
Auxiliary components: 96% ethanol, saccharin, glycerol, sodium bicarbonate, methyl parahydroxybenzoate, menthol flavoring (flavoring), polysorbate 20, purified water.

Indications for use

Tantum verde is prescribed for the treatment of the following inflammatory diseases of the oral cavity and ENT organs (of various etiologies):

Glossitis, gingivitis, stomatitis (including after radiation and chemotherapy);
Tonsillitis, pharyngitis, tonsillitis, laryngitis;
Calculous inflammation of the salivary glands;
Candidiasis (simultaneously with other drugs);
Periodontal disease.

For inflammatory and infectious diseases that require systemic treatment, Tantum Verde should be used as part of combination therapy.

Tantum verde is also prescribed after tooth extraction or treatment, injuries and surgical interventions (jaw fractures, tonsillectomy, etc.).

Contraindications

Phenylketonuria (for lozenges);
Age up to 3 years (for spray and lozenges) or up to 12 years (for topical solution);
Hypersensitivity to the drug.

According to indications, it is possible for nursing and pregnant women to use Tantum Verde in the form of a solution for topical application and a spray.

Dosage and administration

Tantum Verde is applied locally. The dosage regimen is determined by the dosage form:

Resorption tablets: 3-4 times a day, 1 tablet each. The tablet should be kept in the mouth until completely resorbed (preferably as long as possible, which will provide the greatest effectiveness);
Solution for local use: 2-3 times a day in the form of rinsing the mouth or throat, 15 ml per rinse (for accurate dosing, use a measuring cup). In inflammatory processes, an undiluted solution is used; for daily hygienic rinses of the oral cavity and throat, a diluted solution should be used (15 ml of Tantum Verde and 15 ml of water are mixed in a measuring cup);
Topical spray: every 1.5-3 hours. Adults and elderly patients - 4-8 doses, children 6-12 years old - 4 doses; children 3-6 years old - 1 dose for every 4 kg of body weight (maximum - 4 doses).

Side effects

During therapy, the following side effects may develop:

Allergic reactions: skin rash;
Local reactions: burning sensation or numbness in the oral cavity, dry mouth;
Other: very rarely - laryngospasm.

special instructions

If during the application of the solution there is a burning sensation, it must first be diluted with water in a ratio of 1: 1 (you should bring the water level to risks on a graduated glass).

Avoid contact with eyes.

Drug interaction

Clinically significant interaction of Tantum Verde with other drugs has not been established.

Terms and conditions of storage

Store in a dark place, out of reach of children at temperatures up to 25 ° C.

Shelf life is 4 years.