Chophytol duration. Chophytol and side effects

Instructions for use:

Hofitol is a herbal preparation with pronounced choleretic and diuretic properties, which reduces azotemia.

pharmachologic effect

The main active component of the composition of the drug Hofitol are artichoke leaves, rich in a complex of vitamins, trace elements and other biologically active substances.

Due to the action of phenolic acids in combination with cinarin, Hofitol has a choleretic and hepatoprotective effect.

Inulin, ascorbic acid, B vitamins, in particular, B1 and B2, as well as carotene, have a normalizing effect on the metabolic processes of the body.

In addition, important pharmacological effects of the drug, according to reviews about Hofitol, are increased urine excretion and the diuretic effect of the drug.

Hofitol release form

Hofitol is available in three different forms.

Brown coated tablets. In pharmacy chains, there are two types of packaging: 60 or 180 tablets in bottles or blisters;

120 ml oral solution in a vial;

Injection. Packed in ampoules with a self-tapping tip of 5 ml. Ampoules in the amount of 5 pieces are placed in a package.

Indications Hofitol

The drug, as a rule, is used as part of complex therapy. Indications for Hofitol are listed below:

Non-calculous cholecystitis in a chronic form;

Biliary dyskinesia according to the hypokinetic type;

Hepatitis in chronic form;

Jade in chronic form;

Cirrhosis of the liver;

Chronic renal failure.

Contraindications

Hofitol and analogues of the drug, as a rule, are well tolerated, but are contraindicated for some groups of individuals. Their list is given below:

Patients with gallstone disease;

Patients with obstruction of the biliary tract;

Patients diagnosed with acute diseases of the kidneys, liver, urinary and biliary tract;

Patients with hypersensitivity to the components of the drug.

The instruction for Hofitol in the form of tablets warns of the impossibility of prescribing the drug to children under 6 years of age.

Instructions for use Hofitola

The dosage when taking the medicine depends on the age of the patients.

Adults, according to the instructions for Hofitol, it is recommended to take the drug inside 3 times every day, 2.5-5 ml of solution or 2 or 3 tablets. The course of treatment most often is 2 or a maximum of 3 weeks.

Hofitol children should take 1 to 2 tablets daily before meals. A solution of the drug is taken in a quarter or half of the dose prescribed to adults, also 3 times a day. The duration of treatment is up to 3 weeks. It should also be noted that, according to medical reviews about Hofitol, the medicine is intended for the treatment of children over 6 years old.

If necessary, repeat the course of treatment should receive medical advice.

Side effects of Hofitol

As a rule, during treatment with the drug side effects do not occur. However, in extremely rare cases, the appearance of unwanted reactions is possible even with obvious indications for Hofitol and the absence of contraindications. First of all, this reaction of the body is caused by prolonged use of the drug in high doses.

Among the side effects, allergic reactions and diarrhea are known.

special instructions

The use of Hofitol during pregnancy and lactation is permissible only with the permission of the doctor and constant medical supervision.

Hofitol analogues

Preparations similar in composition and manner of exposure to the body to Hofitol include:

Artichoke extract;

Cholebil.

Storage conditions

Hofitol is stored at a temperature not exceeding 25 ° C in a place located out of the reach of children. Shelf life under all conditions is 3 years for tablets and 4 years for solution.

Hofitol is made on the basis of extracts from field artichoke. This component of the drug is often and successfully used to treat kidney and liver diseases.

Often with liver diseases, a very popular drug hofitol is prescribed. The instructions for use report that this herbal medicine is recommended for use in diseases such as liver cirrhosis.

The drug has a choleretic effect - an extract from the field artichoke, which is the main component of the drug, is indicated for the treatment of kidney and liver diseases.

The method of application, compatibility with other medicines, effects on pregnancy, side effects, each contraindication and indication, the patient should find out and evaluate before treatment.

The artichoke activates the formation and secretion of bile, lowers the level of cholesterol in the body, and also has a diuretic effect. The medicine is recommended for use in such diseases:

• chronic hepatitis;
• inflammatory processes that strike the gallbladder;
• liver pathology, cirrhosis;
• nitrate intoxication, other intoxications.

Chophytol is effective for poisoning the body with alcoholic beverages, for atherosclerosis, and also if the patient is observed (for example, with a decrease in the daily volume of urine).

Doctors can also prescribe a drug for heart disease, psoriasis, fungal infections of the nails, nausea, people diagnosed with kidney failure (but only in the early stages). Hofitol is recommended for use by patients who have problems with excess weight (for example, obesity).

It is forbidden to prescribe or continue to take the drug, unless obstruction of the biliary tract is ruled out.

Contraindications

The drug Hofitol is prohibited for patients who have previously been diagnosed with pathologies of the liver and gall bladder in the later stages, with obstruction of the biliary tract.

You can not take the drug for liver and kidney failure, which manifests itself in acute form, if the patient has an increased sensitivity or individual intolerance to any of the components of the drug.

Like any other drug, hofitol has side effects. If you take the drug for a long time and in relatively high doses, the patient may begin to be disturbed by pain, cramping in the abdomen.

In the process of treatment, there is a feeling of heartburn, nausea, diarrhea. In some patients taking the drug, minor rashes, redness, and itching appear on the skin.

Release form. The medicine is produced in the form of tablets and solutions. Each tablet (capsule) is coated, has a round shape, a brownish tint.

One package of injection means contains 5 ampoules, each ampoule - 5 milliliters.

Hofitol in the form of a solution for oral administration is made in bottles with a special dispenser. One bottle contains 200 milliliters of the drug. It must be remembered that ethanol is the basis of this form of medicine.

How to take hofitol

The dosage of the medicine and the course of treatment are determined by the specifics of the patient's disease, his age, and anamnesis. The drug is taken before meals. Before drinking a liquid solution, it must be thoroughly shaken.

It should be borne in mind that the drug does not adversely affect the ability to concentrate attention and reaction speed, therefore, there are no professional restrictions. Nevertheless, if side effects have appeared after taking the medicine, you must refuse to drive vehicles and mechanisms.

If we are talking about the drug in the form of drops, then special care should be taken, since each drop of the solution contains ethyl alcohol.

Depending on body weight, adults are prescribed 1 or 2 tablets up to three times a day. As a solution, adults also take the drug 3 times a day, 1/2 or one teaspoon.

Usually, the course of treatment does not exceed three weeks, but under certain circumstances, the doctor may extend it for up to a month.

Injections are administered once a day. The dosage is from 5 to 10 ml. If necessary, the doctor can correct it. As a rule, injections are administered for one to two weeks. After this, the patient is recommended to switch to other forms of release and take the drug inside.

Pediatric use

The medicine can also be prescribed for children. Typically, the drug is prescribed if the baby suffers from jaundice, chronic or acute hepatitis, cholecystitis. The drug is indicated in cases where the newborn suffers from cirrhosis of the liver, dyskinesia, renal failure, diseases that affect the skin (for example, acne, psoriasis), obesity and other disorders.

Despite the fact that the drug is considered absolutely harmless to the child's body, it is nevertheless necessary to give hofitol to children with extreme caution. First of all, the doctor must choose the right dosage so that not a single possible side effect develops.

How to give hofitol to a newborn and an older child should be checked with a doctor. The medicine in the form of tablets is not prescribed for children under 6 years old, from 6 to 12 years old it is possible to use tablets - the daily norm is one tablet up to three times a day.

Children under the age of one year are prescribed the drug in the form of drops. The optimal dosage is up to 10 drops per day, three times. They are diluted with water, taken before meals.

Patients under the age of 15 are also injected with the drug. The daily rate is 1/2 ampoule once a day. If there is a need to increase the dosage, the patient is transferred to inpatient treatment, and the drug is strictly controlled by the attending physician.

Pregnancy

It is possible to take hofitol during pregnancy in the early stages, but exclusively for the preventive purposes of gestosis in the later stages. If the drug has therapeutic goals, then it should be part of a comprehensive course of therapy directed against the development of signs of late gestosis (protein in the urine, swelling, preeclampsia).

Usually, the dosage of the drug during pregnancy is equal to the amount that adult patients take. There are no clinical data on the effect of hofitol on breastfeeding.

The main analogue of the drug is Heptral, which is available in the form of tablets and injections. The doctor can also prescribe Holiver (considered the most affordable), Hepatophytum, Odeston.

Conclusion

Hofitol is prescribed for diseases of the liver, kidneys, has a choleretic effect. It can be taken not only for adults, but also for adolescents and children. The medicine is allowed to be taken during pregnancy, and Hofitol for newborns is shown. The optimal dosage in such cases is chosen by the doctor, based on the state of health of the small patient.

Despite the fact that the drug is considered relatively "harmless", self-medication cannot be used with it. If we are talking about increasing the dosage, the patient should be in a hospital, under the constant supervision of a doctor.

Hofitol is a plant-based hepatoprotector.  It has a small list of contraindications and side effects, therefore, according to the instructions, it is recommended for children from birth.

Thanks to the diuretic effect, it helps to eliminate toxins, metal salts from the body, enhances the production of liver puncture tape and removes urea, improves cholesterol metabolism.

Hofitol for children - the instruction indicates the possibility of use for dyspepsia, intestinal disorders in order to restore liver function, in particular for pregnant women after taking heavy antibiotics.

Release form, composition and packaging

Hofitol is available in:

• tablets (60-180 pcs);
• injection (100 mg 1 ampoule);
• suspensions (200 ml) in the form of a thick extract of artichoke, which is preferred for children;
• syrups (120 ml) in vials.

By composition, the tablets contain:

• vole artichoke (dried water extract);
• excipients: rosin, talc, sucrose, gelatin, dispersed dye, calcium carbonate.

Solutions:

• water extract of field artichoke;
• ethyl alcohol, orange flavor, purified water, methyl parahydroxybenzoate, dietary supplements E218 and E 216.

Injection:

• field artichoke (leaves) purified extract;
• distilled water (5ml).

The form of packaging is cardboard. Tablets are placed in polypropylene tubes, blisters.

pharmachologic effect

Artichoke, as an active component with dietary supplements (ascorbic acid + vitamins + phenol acids + carotene) has a choleretic, diuretic, diuretic effect, and has a beneficial effect on the functions:

• liver, enhancing the excretion of bile;
• kidneys, increasing the volume of excreted urine.

Thanks to excipients, metabolism in children in the liver cells is normalized. When taking Hofitol, a hepatoprotective effect is observed.

A drug:

• normalizes metabolic processes;
• activates bile secretion and bile formation;
• reduces urea, cholesterol in the blood.

During clinical observations, it was proved that Hofitol actively affects the affected areas, thanks to the active particles in the composition.

Indications for use for children

Hofitol for children is indicated for use in hepatitis, acetonemia against the background of an increased level of acetone in the blood.

The main indications for use:

Hofitol for children is used for:

• insufficient urine output;
• overweight;
• the development of inflammation in the kidneys;
• unpleasant symptoms (, vomiting, rotten belching, abdominal discomfort,);
• heavy metal poisoning (salts);
• dyspepsia.

According to the instructions, it is prescribed for many diseases of the gastrointestinal tract, since it is considered a safe and effective drug and is recommended for use by babies from birth.

Instructions for use Hofitola

Before use, according to the instructions of Hofitol, it is important to consider weight and age.

Recommended daily dosage form:

• tablets - 2-3 pcs;
• syrup to infants up to 1 year, 10 drops 3 times by diluting in 5 ml of warm water;
• capsules with jaundice - 1-2 pcs. 3 times;
• a solution for iv in / m in injections - 2.5-3 ml 3 times.

Dosage per day for children, taking into account age:

• 1-3 years - 0.5 tablets 3 times;
• 3-6 years - 1 tablet 2 times;
• 6-12 years - 1 tablet 3 times.

The treatment course is 2-3 weeks. In order to prolong the therapy, you should consult a doctor. Injections are prescribed for children with a duration of up to 15 days, then, according to the doctor's prescription, it is possible to switch to oral administration of syrup or tablets.

If drops are used, then before use, the bottle must be shaken to prevent the precipitate from entering the body. Drops by dilution in water is the recommended form of taking Hofitol for children from birth.

It is better to give the drug according to the instructions, on an empty stomach up to 3 times a day:

• infants up to 1 year old - 7-8 drops with stirring in 5 ml of water;
• 1 year-5 years - 10-20 drops and 15m l of water;
• 6-12 years - up to 60 drops and 15 ml of water;
• 12-18 years old - 1 tsp Hofitola + 15 ml of water.

The use of hofitol during pregnancy and lactation

Thanks to the composition, Hofitol has a positive effect on the female body as a whole during pregnancy.

Promotes:

On a note!  Women are allowed to take Hofitol if the benefit in relation to the possible risks to the fetus is justified.

So, when gestosis is detected at the beginning of pregnancy, the effect will be much higher than the allowable harm to the baby.

A drug:

• it has an antioxidant, hepatoprotective effect;
• minimizes lipid degradation and oxidation;
• creating a protective barrier to the liver;
• enhances the separation of bile;
• has a diuretic effect;
• lowers cholesterol;
• normalizes blood circulation in the placental barrier.

It is possible to prescribe the drug to pregnant women with atherosclerosis and an inflammatory course in the urinary tract. According to the instructions, Hofitol is able to improve general well-being, when drowsiness, dizziness, headache, and weakness are observed in the first trimester.

During pregnancy, the fluid stagnates excessively in the tissues, which is fraught with complications and serious pathologies. Hofitol normalizes the function of blood vessels and kidneys, prevents the formation of dropsy and edema.

Attention!  Hofitol for children is not an antibiotic, therefore, it is unlikely to be effective for lesions of a bacterial infection. Additional use of other uroseptics is required.

Do not neglect doses.  The average dosage per day is 50 mg. The course of treatment is 3 weeks. Women during pregnancy can be taken in the form of a syrup - 1 tsp. or 5 ml 3 times a day with a treatment course of 2 weeks.

The frequency and duration of the course is selected exclusively by the attending physician individually. Data on how safe the drug is for women during lactation has not been identified.

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Contraindications

Manufacturers claim that Hofitol is a completely safe drug.

When taking tablets, it is necessary to comply with the dosage, evaluate all possible contraindications and possible side effects.

Side effects

Rarely, but side effects can occur:

• allergy;
• rash, itching, urticaria by type of burns;
•   loose stools;

If appeared:

• stomach pains;
• vomiting
• pain in the hypochondrium on the right;
• itching, peeling;
• dermatitis;
• digestive disturbance, the drug should be postponed and consult with a specialist.

According to patients, Hofitol for children is better tolerated in oral solutions.

Overdose

No cases of overdose have been identified. Rarely, a solution of Hofitol for children can translate into pathological reactions from the gastrointestinal tract.

Drug interaction

Hofitol contains ethyl alcohol, so it is undesirable to use it in combination with the following drugs:

• cephalosparins (cefamandol);
• 5 nitroimidazole derivatives (Tinidazole, Metronidazole, Ornidazole);
• cytostatics (Procarbazine, Sulfonylurea, Glipizide, Tolbutamide, Disulfiram, Chloramphenicol).

Disulfiram-like reactions, the appearance of nausea, redness on the skin, sensations of heat, attacks of tachycardia are possible. In particular, there may be adverse reactions when taking Hofitol to children in combination with antifungal agents (Ketoconazole, Griseofulvin).

If additional drops with an alcohol content are also used, then a decrease in the effect and suppression of functions by the central nervous system are possible.

special instructions

If there are unpleasant signs (nausea, diarrhea, abdominal pain), the drug should be stopped and consult a doctor.

It is extremely cautious to give Hofitol to children with diseases of the biliary tract and liver, since inadequate reactions, the creation of obstruction or the deterioration of the liver are possible.

According to the injection instructions, Hofitol tablets are not able to slow down reactions and reduce concentration. Drops also contain ethanol, which is necessary for people who control vehicles, other mechanisms.

Cautious reception requires a drug for patients suffering from:

• epileptic seizures;
• pronounced convulsions of the transverse muscles;
• chronic alcoholism;
• traumatic brain injury.

When using Hofitol for children (instructions), it is important to consider the dosage and body weight. It is preferable for babies to be given drops (5-10) by dilution with water (5ml).

Dose for older children:

• 1-5 years  -15 drops;
• 6-12 years old  - 50-60. The medicine should be given before meals 3 times a day.

Inhalation is not recommended for babies up to 3 years. Phytopreparation (field artichoke) has proven its safety and helps to accelerate the excretion of bile, but it can cause cramping, choking due to the inability to expectorate excess babies.

It is best for children under 6 years of age to use the drug in oral solution.  At an older age of children, it is advisable to first consult with a pediatrician before inhaling Hofitol.

Pharmacy Vacation Terms

Hofitol tablets are dispensed without a doctor’s prescription. However, do not neglect the dosages and expiration dates. You need to read the instructions in the package. When using the solution for children, it is advisable to first consult a doctor.

Injections in / in / m should be put exclusively by a specialist, especially when prescribed to children.  Incorrect administration of the drug can lead to side effects, allergic reactions.

Injection solutions are sold exclusively with the permission of the attending physician, i.e. prescription, therefore, when prescribing to children, prior consultation with a pediatrician is necessary.

Storage conditions and shelf life

The optimum temperature for storage according to the instructions from the manufacturers +18 +20 gr.

Shelf life is for:

• tablets - 2 years;
• solution - 3 years;
• syrup - 4 years.

It is necessary to store in a dry, dark place (instruction), in a closed form to avoid moisture, light and away from children.

Drug price

The cost varies depending on the dosage and form of the drug.

Approximate price:

• tablets (60 pcs) - 356 rub  , 180 pcs - 764 rub .;
• injection - 3501 rub.   for 120 ml;
• suspension for oral administration - 633 rub   for 120 ml.

Analogs

Almost all Hofitol analogues for children are similar in composition to the action, contain plant components:

1. , release form - tablets. In the composition - nettle, activated, charcoal, bile to provide hepatoprotective, choleretic effect. Release form - syrup, tablets. In action similar to Hofitol Price 16-30 rub.  for 1 pack.
2. Cholebil  for the treatment of colitis, steatosis, cholecystitis, dyskinesia. As a part - a leaf artichoke. Children can be given capsules up to 2 times a day in conjunction with food and drink. The treatment course is up to 4 weeks. Price - 46-60 rub.
3. Artichoke, extract with the form of release in capsules, tablets. As a part - dry extract of artichoke. It has a hepatoprotective, diuretic, intoxication effect. Helps normalize liver function, enhance the outflow of bile secretion. Indicated for use in children from 6 years of age, 100 mg 3 times a day for hepatitis (chronic form), urolithiasis, obesity, dyspepsia, impaired gallbladder motility. Cost - 115-118 rub.
4. as a choleretic agent with a release form in tablets (200 mg) of a light shade. Sold in blisters of 50 pieces, has a selective, antispasmodic effect. It does not affect pressure, but it perfectly eliminates stagnation of bile, prevents the crystallization of cholesterol. It is indicated in the treatment of biliary dyskinesia, cholecystitis, in the postoperative period on the biliary tract, with constipation, loss of appetite, nausea. The dosage per day should not exceed 1200 mg. Price - 390-490 rub.
5.   (tablets). The composition includes methionine, silicon dioxide, carboxymethyl starch, magnesium stearate. Available in tablets or lyophilization for the preparation of solutions. It has antidepressant, antioxidant, choleretic effects. It is indicated in the treatment of liver cirrhosis, cholecystitis, non-calculous angiovitis, fatty hepatosis, allopathy, and liver failure. Attention!  Children under 17 years old are not recommended. Side effects are possible: abdominal pain, nausea, diarrhea, laryngeal edema, insomnia, dizziness, dry mouth. Cost - 1900 rub.
6. Oxafenamide  It is indicated for diseases: dyskinesia, cholecystitis, cholangitis, chronic hepatitis. It has an antispasmodic, choleretic effect. Cost 10-26 rub.
7. Hepatophyte  to provide hypoglycemic effect in case of problems with the liver, biliary tract. It contributes to the improvement of antitoxic function, increased bile secretion, the provision of antispasmodic action. It is indicated for cholangitis, dyskinesia, diabetes mellitus, chronic hepatitis. Not recommended for children under 2 years of age, although no cases of overdose have been identified. Cost - 130-150 rub.
8.   in tablets (50 mg). In the composition - immortelle flowers. The drug has anti-inflammatory, antibacterial, choleretic effect, enhances the secretion of bile, increases the content of bilirubin. It treats cholecystitis, inflammation in the tissues of the liver, bile ducts. No cases of overdose have been identified. The cost in pharmacies of Russia - 50 mg 30 pieces - 100-250 rub.
9. Holiver, in the composition - sowing artichoke, corn, turmeric, bile acids. The drug has an antiseptic effect, helps to stimulate intestinal motility, increase bile secretion, remove cholesterol from the blood, eliminate signs of flatulence and severity after eating. It is recommended for diseases: oliguria, cholecystitis, cirrhosis, chronic hepatitis, biliary dyskinesia. Price - 60 rub
10. Arnica Tincture - water decoction. It is indicated in the treatment of boils, lumbago rash, cuts, bruises, pustules on the skin, as well as to normalize cardiovascular activity. Attention! Arnica is a poisonous plant, so before taking tinctures, it is better to consult a doctor first. Overdoses are unacceptable in order to avoid trouble. It is important to consider contraindications. Price - 50-60 rub.
11. Berberine  in tablets, the active substance is berberine bisulfate. It has a choleretic, antispasmodic effect. It is indicated in the complex treatment of chronic hepatitis, cholecystitis, dyskinesia, hypokinetic peptic ulcer. Price - 74 rub   for 30 tablets.
12.   capsules, has a choleretic, hepatoprotective effect. It is indicated for chronic hepatitis, biliary dyskinesia. Do not give to children under 18 years of age. With excessive hypersensitivity to the components of the capsules in pediatrics, the drug is not used. Price - 430-480 rub.
13. Canvaflavin  with the provision of antispasmodic, choleretic action. Absolutely non-toxic, indicated for cholangitis, cholecystitis. Available in bottles, cost - 180-190 rub.
14. Leptandra  It has a cholinergic, choleretic antiemetic, anti-inflammatory effect. It is indicated in the treatment of jaundice, gastralgia, dysentery, diarrhea, biliary colic, inflammation, flatulence, epigastric pain, heartburn. Children under 12 years old are allowed. Price - 107-180 rub.
15. Olimetin  in capsules. Herbal preparation is indicated for hepatitis, anuria, renal failure, impaired urination, hypersensitivity. Olimetin is not sold in pharmacies, so the cost has not yet been identified.
16. Tanacehol  in tablets for cholagogue. It is indicated for cholecystitis, inflammation of the gallbladder, dyskinesia, postcholecystectomy syndrome. Price - 60 rub  for packing.
17. Holagol  in composition with turmeric, essential oils. It is produced in drops, has a laxative, antispasmodic, choleretic effect. It is indicated for children with cholangitis, biliary colic, cirrhosis, epidemic hepatitis, cholecystitis, cholelithiasis. Price - 259-336 rub.

Substitutes having a similar effect:

• Cyqualone;
• Cholemax;

    The drug contributes to:

  • removal of decay products from the biliary tract;
  • normalization of the functions of the gastrointestinal tract;
  • getting rid of constipation;
  • providing a choleretic effect.

  Allochol contains natural ingredients and is cheaper. Which is better - Allohol or Hofitol? It's hard to answer. Drugs successfully fight bile formation, normalize digestion processes. At the heart of Hofitol is an artichoke extract, at the base of Allochol is also an artichoke.

  But, according to patients, Allohol is more effective, because it quickly and easily eliminates constipation, enhances intestinal motility, eliminates fermentation processes and signs of flatulence.

  Hofitol and Allohol are excellent choleretics, they stimulate the production of bile acids, increase the secretion of bile.

  Chophytol additionally has a protective effect. Both drugs are bile-containing, so only the attending physician will help you choose the best remedy.

  Hofitol for children is not able to cope with such problems alone, although it has proved effective in the treatment of:

  • psoriasis;
  • hepatitis A;
  • dyskinesia;
  • jaundice;
  • constipation.

  Positive dynamics and improvement of the skin integument are noted.  The price of Hofitol is quite reasonable. This is a natural plant composition, does not lead to side effects. It can be given to infants and consumed by women during pregnancy.

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  Phytopreparation with choleretic and diuretic effect, reducing azotemia.
    Preparation: HOPHITOL
  The active substance of the drug:   Cynara
    ATX Encoding: A05BA
    KFG: Phytopreparation with choleretic and diuretic effect, reducing azotemia
    Registration number: P No. 013320/02
    Date of registration: 12/11/07
    Owner reg. doc .: Laboratoires ROSA-PHYTOPHARMA (France)

  Hofitol release form, drug packaging and composition.

  Brown coated tablets are round, biconvex.

  1 tab
    dry water extract of fresh leaves of artichoke field
    200 mg

  Excipients: magnesium trisilicate, corn starch, talc, magnesium stearate.

  Shell composition: gummilak, rosin, talc, gelatin, acacia gum, sucrose, calcium carbonate, carnauba wax, polysorbate 80, disperse dye (sucrose, yellow, black and brown iron oxides (E172), methyl parahydroxybenzoate (E218), ethyl parahydroxybenzoate )

  12 pcs - blisters (5) - packs of cardboard.
    30 pcs - blisters (2) - packs of cardboard.
    30 pcs - blisters (6) - packs of cardboard.
  180 pcs. - polypropylene tubes (1) - packs of cardboard.

  The solution for oral administration is dark brown, opaque, with a slight yellowish precipitate; possible slight sediment during storage.
    1 ml
    thick water extract of fresh leaves of artichoke field
    200 mg

  Excipients: ethanol, orange flavor, glycerol, methyl parahydroxybenzoate, propyl parahydroxybenzoate, purified water.

  120 ml - bottles of dark glass (1) - packs of cardboard.

  The solution for intravenous and intramuscular administration is clear, colorless to dark yellow.
    1 ml
    1 amp
    Refined Artichoke Fresh Leaf Juice Extract
    20 mg
    100 mg

  Excipients: purified water.

  5 ml - glass ampoules (5) - packs of cardboard.

  The description of the drug is based on officially approved instructions for use

  Pharmacological action Hofitol

  The drug is of herbal origin. The pharmacological effect of the drug is due to a complex of field biologically active substances that make up the leaves of the artichoke. Cinarin in combination with phenolic acids has a choleretic, as well as hepatoprotective effect. Ascorbic acid, carotene, vitamins B1 and B2, inulin contribute to the normalization of metabolic processes.

  It also has a diuretic effect and enhances urea excretion.

  Pharmacokinetics of the drug.

  The effect of the drug Hofitol is the combined effect of its components, so kinetic observations are not possible; collectively, components cannot be traced using markers or bioassays. For the same reason, it is impossible to detect the metabolites of the drug.

  Indications for use:

  As part of complex therapy:

  Biliary dyskinesia according to the hypokinetic type;

  Chronic non-calculous cholecystitis;

  Chronic hepatitis;

  Cirrhosis of the liver;

  Chronic jade;

  Chronic renal failure.

  Dosage and route of administration of the drug.

  Adults are prescribed 2-3 tablets. or 2.5-5 ml oral solution 3 times / day before meals. The course of treatment is 2-3 weeks.

  With iv or intramuscular administration, 5 ml is prescribed 1-2 times / day. The duration of treatment is 8-15 days. The dose may be increased, especially with inpatient treatment.

  Children over 6 years of age, depending on age, are prescribed 1-2 tablets. 3 times / day before meals. A solution for oral administration, depending on age, is prescribed in 1 / 4-1 / 2 of the dose used in adults, 3 times / day before meals. The course of treatment is 2-3 weeks.

  With intravenous or intramuscular administration, the drug is prescribed at a rate of 2.5-3 mg / kg body weight 1 time / day.

  The doctor determines the need for repeated courses of therapy individually.

  Side effect of Hofitol:

  From the digestive system: diarrhea may develop with prolonged use of the drug in high doses.

  Other: allergic reactions.

  Contraindications to the drug:

  Cholelithiasis;

  Bile duct obstruction;

  Acute diseases of the liver, kidneys, bile and urinary tract;

  Children's age up to 6 years (for tablets);

  Hypersensitivity to the components of the drug.

  Use during pregnancy and lactation.

  There are reports that the use of Hofitol in the complex treatment of preeclampsia improves the clinical course of the disease. Hofitol is used in a complex of preventive measures at a risk of developing gestosis from early pregnancy.

  Data on the safety of the use of the drug Hofitol during lactation (breastfeeding) are not provided.

  Special instructions for the use of Hofitol.

  With prolonged use of the drug in high doses, the risk of developing diarrhea increases.

  1 teaspoon of the oral solution contains 130 mg of ethyl alcohol.

  Overdose of the drug:

  Symptoms: may increase the manifestations of side effects.

  Interaction of Hofitol with other drugs.

  The drug interaction of the drug Hofitol is not described.

  Terms of sale in pharmacies.

  Hofitol in the form of coated tablets and oral solution is approved for use as an over-the-counter drug.

  Hofitol in the form of an injection is prescription.

  Terms of storage conditions of the drug Hofitol.

  The drug should be stored out of the reach of children at temperatures above 25 ° C. The shelf life of the tablets is 3 years, the oral solution is 4 years, the injection solution is 2 years.

  Plant extracts have been used in pharmacology for several years. Their effect is milder than that of synthetic active substances, but they guarantee a minimum amount of undesirable effects and, with few exceptions, have no contraindications. So, Hofitol - a drug made from an extract of an artichoke plant, is indispensable in any home medicine cabinet.

  Hofitol

  Hofitol has a systemic effect on the filtration systems of the body, improving the activity of the liver and kidneys, normalizing the composition of the blood and helping to remove fluid from the body. Hofitol is used for somatic pathologies of various systems, and is often prescribed by doctors and in nephrology.

  Composition

  Hofitol has a one-component composition, that is, the main active substance of its composition is one component - an extract (extract) from artichoke leaves.

  Depending on the form of release, it can be taken in the form of:

  • dry extract (tablets);
  • thick extract (oral solution);
  • purified juice extract (solution for intravenous and intramuscular administration).

  Additional ingredients are also used that help preserve their therapeutic properties, contribute to the best acceleration of the medication by the body.

  For tablets:

  • magnesium trisilicate - for antacid (antacid) action;
  • magnesium stearate - emulsifier;
  • corn starch - a natural polymer;
  • talc is an absorbent with disinfecting properties.

  For a solution intended for oral administration:

  • glycerol is a solvent;
  • alcohol solution of citrus juice - flavoring;
  • ethanol - a catalyst for the rapid penetration of active components into the blood;
  • dye;
  • water.

  For injection: distilled water.
    Thus, Hofitol has the most natural and effective composition.

  Release form and prices

  The tablet form of Hofitol is the most popular among buyers. 0.2 g coated tablets are packed in blisters or tubes and cardboard boxes.

  There are 4 types of Hofitol in tablets:

  • 12 pcs - worth 74 rubles;
  • 30 pcs - worth 185 rubles;
  • 60 pcs. - worth 340 rubles;
  • 180 pcs. - worth 780 rubles.

  A solution for oral use (drops) in a 120 ml bottle, packed in a pack of cardboard, will cost the buyer 420-440 rubles.

  Operating principle

  Artichoke extract, which is the main active substance, has an effect in three directions, such as:

  • diuretic;
  • hepatoprotective;
  • choleretic agent.

  First of all, Hofitol acts on the liver, as a result of which there is an increase in the production of coenzymes that affect the chemical composition of the blood.

  Both the resulting improvement in liver function and the direct effect of the drug have a beneficial effect on the gallbladder, eliminating the outflow of bile, normalizing the activity of the digestive system.

  Under the influence of artichoke extract increases diuresis, mainly due to the elimination of lymph stagnation. Therefore, electrolyte imbalance, as with conventional diuretics, does not occur. Moreover, many patients report a decrease in blood pressure when taking the drug. This is due to the removal of excess fluid from the bloodstream.

  In nephrology, Hofitol is used as a disintoxication agent. Against the background of impaired renal activity, the blood composition changes, the level of urea, cholesterol, uric acid increases. This phenomenon is dangerous with the risk of azotemia - poisoning the body with its own decay products, not removed from the bloodstream by the kidneys. An increase in diuresis, coupled with an effect on the liver as the second filtration system of the body, makes it possible to normalize the blood composition in patients suffering from, and, as a result, improve well-being.

  The principle of the drug
  
  

  Indications

  Hofitol is used for various pathologies, since its effect, like any composition on a natural, plant basis, is systemic.

  Liver pathology:

  • cirrhosis - the death of organ cells with subsequent replacement by fibrous tissue;
  • hepatitis - a term that combines inflammation in the liver of viral origin;
  • cholecystitis - inflammation localized in the gallbladder;
  • biliary dyskinesia - a violation of the outflow of bile.

  Pathology of the urinary system:

  •   - reduced filtration efficiency of glomeruli;
  • chronic nephritis - inflammation in glomeruli, including glomerulopathy.

  Instructions for use

  The standard course of drug therapy is 15-20 days. Tablets are drunk before meals, 2-3 times a day for 2-3 pieces. The oral solution is also designed for three times a day for 2.5-5 ml.

  The use of Hofitol in the form of ampoules for injections is carried out exclusively under the supervision of a doctor, especially since this form is a prescription.

  For children over six years of age, the average dose is approximately half that of adults. So, the instruction recommends that they take 1-2 tablets three times a day before meals, or 1.25-2.5 ml of solution.

  During pregnancy and lactation, Hofitol is prescribed only after consultation with a specialist and under his watchful supervision.

  If after the course arose there is a need for repeated therapy, you need to visit a doctor and get advice on this issue.

  Instructions for use of the drug Hofitol
  
  

  Side effects

  Side effects on the background of taking the drug are extremely rare. Most often they are provoked by intolerance to any ingredient in the composition.

  There is information that when taking Hofitol there is a significant risk of developing diarrhea. In this case, the course must be interrupted, consult a doctor and drink more fluid to prevent dehydration.

  Contraindications

  • obstruction of the biliary tract;
  • acute pyelonephritis;
  • acute cholecystitis;
  • cholelithiasis.

  special instructions

  1. The manufacturer does not provide data on the interaction of the composition with other drugs, so before you start taking the drug while treating with other drugs, you need to consult a doctor or pharmacist.
  2. The drug does not have any effect on the psychomotor functions of the brain, so a person can manage transport during the treatment or perform work that requires increased attention.
  3. The oral solution contains ethyl alcohol, therefore, people with sensitivity to this substance should better buy the drug in the form of tablets.
  4. With an increase in diuresis in the absence of edema, it is necessary to replenish the lost fluid.

  Analogs

  Cheap analogues of Hofitol, with the same composition:

  • Artichoke Extract (Evalar) - 120 rubles for 20 tablets;
  • Artichol - 150 rubles for 30 tablets.

  Medicines that have a different composition, but a similar mechanism of action, are:

  • Heptral - 1700 rubles for 20 tablets;
  • Hepatophyte (drops) - 1200 rubles per bottle of 30 ml;
  • Holiver - 235 rubles per 100 tablets.