Psoriasis Drug Research Program c. Russia has a new drug for the treatment of psoriasis

  • Date: 01.07.2020

Together with creams and ointments, psoriasis tablets play a significant role in complex treatment. Today we will consider such effective tablets for psoriasis as Neotigazon, Methotrexate, Psorilom, Laminin, Milgamma, Lecithin and Befungin.

Quite successfully, psoriasis is being treated with pills both inpatients and in sanatoriums and clinics. Tablets, like, are being developed by dermatologists around the world. But, unfortunately, even the most effective pills will not help.

Treatment of psoriasis with tablets is a complex therapy along with ointments, creams, lotions. Complex therapy assigns a very important role in the treatment of psoriasis to vitamins. They have a positive effect on the processes in the skin, in metabolism. Many vitamins, as a remedy for psoriasis, are part of the tablets. In addition, psoriasis tablets are quite convenient to use.

Neotigazon tablets for psoriasis

Tablets from psoriasis Neotigazon are prescribed for especially severe forms. Therapy is continued until sufficient recovery of the skin. When there are violations in keratinization, Neotigazon for psoriasis used for a long time, but use the minimum effective dose. The most effective pills for psoriasis, if they are washed down with milk.

Methotrexate tablets for psoriasis

Psoriasis pills Methotrexate is a classic systemic treatment and brings good results, especially in severe forms. methotrexate for psoriasis performs the function of a cytostatic drug - inhibits excessive division of skin cells. Methotrexate tablets are similar to folic acid and have an immunosuppressive effect. Read more about this tool in the publication on our website.

Tablets Psorilom

Tablets for psoriasis Psoril are included in the complex treatment for skin lesions of less than 20%. Therapy lasts more than two months, after which a month break is required. Psorilom tablets for psoriasis should not be swallowed: the tablets are kept under the tongue until they dissolve on their own. One dose is 3 tablets. You should drink 9 tablets per day. Psorilom should be taken separately from food.

Information from the Internet, but what is it really !? I can say with accuracy that Psorilom tablets will not help in the treatment of psoriasis. They have a positive effect on the immune system, but no more, although this is also important in psoriasis. Read more about the drug in the article on our website.

Tablets Laminin

Psoriasis tablets Laminin have thousands of positive reviews and a lot of results. Laminin for psoriasis provides balanced nutrition for cells, restores aging, nourishes new ones. Laminin tablets increase the serotonin necessary for the body, promote the production of collagen, and restore DNA molecules. Of course, I will add that they are ineffective for psoriasis.

Folic acid

In psoriasis, the body is deficient in folic acid, and ambiguous symptoms may occur. Folic acid for psoriasis evens out pigmentation, cleanses the skin. Effective folic acid tablets allow you to cope with the disease much faster and prevent megaloblastic anemia. Actively participating in hematopoiesis, folic acid is considered indispensable in the treatment of early stages and often contributes to a complete cure for the disease. As such, they are not effective in psoriasis, but are sometimes used in the treatment regimen.

Milgamma tablets

Psoriasis tablets Milgamma is a multivitamin that has an effect on degenerative nervous diseases. The regimen is prescribed by the doctor, but in the absence of an exacerbation, a tablet per day is enough. Milgamma for psoriasis contraindicated in severe form and sensitivity to the components of the drug. Milgamma is also not given to newborns and pregnant women.

Tableted Mumiye

It is difficult to imagine a cure for psoriasis without Mumiyo. Healing natural balm - Mummy for psoriasis allows treatment at home. There is a rapid stimulation of the patient's condition. The use of Shilajit tablets allows the body to resist this serious illness. Many folk recipes include Mumiyo. The purified preparation is a serious help in getting rid of psoriasis of any form. I can’t add anything from myself, I haven’t seen it in my practice.

Tablets Lecithin

Tablets from psoriasis Lecithin significantly reduce the duration of treatment, eliminate the torpidity of the disease, and reduce the number of relapses. Lecithin has no side effect. It is recommended even for psoriasis with impaired fat metabolism and high cholesterol. Lecithin tablets for psoriasis are widely used in the complex treatment of psoriasis as vitamins.

Befungin tablets

Tablets from psoriasis Befungin well increase immunity with prolonged psoriasis, restore hematopoiesis. Befungin consists entirely of natural extracts: St. John's wort, as well as chaga. Befungin tablets with psoriasis alleviate the symptoms, and do not cause dependence when taken for a long time. Reception is stopped at the first sign of intolerance to the drug. They act as a means to improve the patient's condition.

Program "Pill" about psoriasis

At the beginning of 2016, on Channel 1 comes out transfer Tablet about psoriasis, which discusses various remedies and drugs for psoriasis. Channel One and the Tabletka program do not cooperate with pharmaceutical companies, so the discussion of tablets and other means for the treatment of psoriasis takes place in the interests of the viewers of our site.


Psoriasis (scaly lichen) is a fairly common chronic disease that is found in 3% of all inhabitants of the earth. As a rule, each patient knows that it is impossible to completely get rid of this disease, however, there are currently new methods of treating psoriasis that contribute to a long-term remission.

These methods are aimed at preventing increased cell formation, which causes an inflammatory process, however, it should be borne in mind that modern methods in no way negate traditional therapy, but, on the contrary, demonstrate the most effective results when used in combination.

List of modern methods of therapy

It is not always possible to achieve the desired result with traditional therapy, and the improvement is short-lived, so more and more new ways to get rid of this disease are being developed:

Ichthyotherapy. This technique is recommended for the treatment of psoriasis vulgaris. To get rid of psoriatic plaques, small fish Garra rufa are used, which eat the affected area of ​​the skin without affecting healthy skin, as a rule, improvement is noted after 5-6 months after regular ichthyotherapy.

Treatment according to Goekerman. Treatment according to Goekerman is known to many as THERAPY WITH THE HELP OF TAR. The tool is recommended to be applied to psoriatic areas of the skin, but this technique is more effective with the combined use of UV radiation, since tar increases the skin's susceptibility to ultraviolet rays.

The procedure itself is performed as follows:

  • therapeutic mud is heated to a certain temperature (39°C);
  • the ointment is applied for 30 minutes to the area of ​​the skin affected by psoriasis, after which it is washed off with warm water;
  • then the skin must be treated with a hypertonic (saline) solution and moisturized with a cream.

After the procedure, the patient rests for several days under the supervision of the attending physician. In addition, there is a special therapy regimen with tar and anthralin-salicylic acid, a mixture of which is left overnight.

UFO. This method of treatment considered one of the most effective in getting rid of psoriasis. Directly for the procedure, long and medium ultraviolet waves are used. For irradiation, a special fluorescent erythema or quartz lamp with a maximum power of 60 watts is used.

Before the start of the session, the patient is recommended to take special medications that can increase the skin's susceptibility to UV radiation. The maximum therapeutic course is 40 procedures with a break of one day. Before the session, the patient is required to take inside special medications that can increase the sensitivity of the skin to the effects of radiation. The optimal course of treatment is 20-40 procedures with a frequency of one day.

However, it should be borne in mind that UVR is contraindicated in diseases of the gastrointestinal tract, pregnancy, diabetes and tuberculosis, malignant neoplasms, cataracts and diseases of internal organs. In addition, there are certain age restrictions, for example, for patients over 55 years of age and children, this procedure is contraindicated.

PUVA therapy. This treatment strategy is most optimal for severe forms of psoriatic manifestations. Photochemotherapy is performed using a special photosensitizing drug (Psoralen) with simultaneous ultraviolet irradiation. Psoralen increases the sensitivity of the skin to ultraviolet rays.

Despite its effectiveness, this method of treatment has a number of negative manifestations in the form of severe itching, burning and increased dryness of the skin. Perhaps the appearance of nausea, hyperpigmentation, but the most dangerous consequence is the malignant development of skin neoplasms. Therefore, mandatory monitoring of the patient's condition by the attending physician is necessary.

UVB irradiation (narrow band) with Calcipotriol and Betamethasone. This method of treatment allows you to most effectively get rid of negative psoriatic symptoms with the help of ultraviolet radiation and a mixture of 2 ointments. At the same time, ointments enhance the effect of ultraviolet radiation. In addition, Betamethasone has anti-inflammatory, anti-edema, anti-allergic and anti-proliferative effects. Calciferol, in turn, inhibits keratinocyte proliferation.

Innovative medicines. Instead of traditional drugs for the treatment of psoriasis, such as Methotrexate and Prednisolone, in 2016-2017, dermatologists often use Betazon and Diprosan, whose action is aimed at stopping the acute stages of psoriasis. These drugs are intended for intramuscular injection, and the course of treatment should not exceed 5-7 days. The short duration is an advantage of this treatment technique, which minimizes side effects.

The drugs in this group include:

  • drugs with Ditranol (Psorax, Cygnolin, etc.), which suppress the pathological process and prevent the reproduction of histio-and-hematogenous cells;
  • The newest effective drug that directly affects cell division, stops the process of inflammation and corrects the immune system is Psorkutan. A characteristic property of this remedy is a good combination with PUVA therapy, as well as the absence of atrophic changes in the skin at the end of treatment;

  • good performance is shown by the latest topical preparations (Advantan and Elocom). As a rule, these drugs rarely cause side effects. In addition, the absence of chlorine and fluorine in them makes it possible to use them in debilitated patients and young children. A positive effect is observed in 95% of patients who were prescribed these drugs. The duration of treatment is determined only by a dermatologist;
  • Another new way to neutralize psoriatic symptoms is the injectable drug for subcutaneous administration Enbrel, which belongs to the group of biological immunosuppressants. This remedy is prescribed for extremely severe psoriasis, in which traditional methods of therapy are powerless. Enbrel has a strong anti-inflammatory effect and inhibits the pathological process of T-cell division. It is effective in all forms of psoriatic manifestations. The drug is prescribed for 25 mg 2 r. within 7 days or 50 mg. 1 p. in a week.

Therapeutic measures are performed until complete remission, but the total course of treatment should not exceed 6 months.

Positive dynamics in the neutralization of psoriasis is observed in the treatment of drugs that affect directly the protein.

These drugs include Remicade, Stelara, and Etanercept, which are meant to be given intravenously once every 2 to 3 weeks. These agents prevent the destructive effect of a protein that inhibits epidermal cells, which is confirmed by clinical trials.

However, the possibility of developing side effects such as:

  • the appearance of hematomas on the skin after the administration of the drug;
  • possible development of a depressive state, accompanied by apathy and drowsiness;
  • allergic manifestations in the form of redness of the skin, severe burning and itching;
  • violation of the heart rhythm;
  • inflammatory diseases of the pulmonary system;
  • thrombocytopenia and thrombophlebitis.

On a clinical trial

It should be borne in mind that medicine does not stand still, and new drugs and ways to get rid of psoriasis are being developed. One of these drugs, which was actively developed in 2015-2016, but has not yet been used in human treatment, is Dual-F-Nalp. The action of this tool is the deepest possible impact on the epidermis, which allows it to directly destroy the psoriasis genome. However, this drug is currently only undergoing clinical trials in rodents.

Currently, there are various drugs for psoriasis, the pharmaceutical effect of which is aimed at neutralizing the internal and visual symptoms of psoriasis.

To get the maximum effect in the treatment of psoriasis, completely different forms of drugs are used (ointments, lotions, balms, creams, sprays), however, it should be remembered that only an INTEGRATED APPROACH to the treatment of psoriasis can make the result as positive as possible!

Characteristics of drugs for psoriasis

Psoriasis is a chronic disease characterized by periodic remissions and exacerbations of the skin. There are a lot of medications for its treatment (ointments, tablets, sprays, etc.). Medicines for psoriasis reduce skin flaking, itching, redness, and also reduce other negative manifestations on the body that cause discomfort to the patient.

In the treatment of psoriatic manifestations on the skin, as a rule, the “ladder principle” is used, when external drugs for psoriasis of a mild effect are first prescribed, and then (if they are ineffective), the patient is prescribed pills (including hormonal ones), etc.

If such therapy did not help to cope with the negative symptoms of psoriasis, then the most powerful treatment is used - immunosuppressants. Most often, such drugs are prescribed for the development of psoriasis on the head. These drugs show maximum results in treatment, but it is important to remember that they have the highest number of side effects.

Before starting the treatment of psoriasis with drugs, you should consult with your doctor and perform a number of necessary examinations. This will allow you to determine the drugs (tablets, ointments, etc.) that will be most effective IN EACH INDIVIDUAL CASE. It is quite possible that the simple use of an ointment will be enough to eliminate psoriatic manifestations on the elbows, head, knees, skin, etc. or cream to restore the structure of the nails.

external drugs

External medicines include:

  • cream;
  • ointments hormonal and non-hormonal;
  • gels (including for nails);
  • sprays;
  • adhesive plasters for the skin;
  • natural oils;
  • shampoos;
  • sea ​​salt.

The appointment of a particular drug depends on the severity and severity of psoriatic symptoms on the skin.

CREAM. This dosage form is considered the most suitable for the neutralization of skin diseases, especially on the legs and elbows. The components of skin creams are emulsifiers, active substance, water and oils.

Creams containing vitamin D:

CALCIPOTRIOL. This skin drug is an artificial analogue of vitamin D3, which can be combined with steroid drugs. Positive results of Calcipotriol are achieved when combined with UV skin treatment.

CREAM AKRYDERM. The drug has the following effect on the skin:

  • antiexudative;
  • anti-inflammatory;
  • antiallergic;
  • decongestant and antipruritic.

The active substance of the drug Akriderm is betamethasone dipropionate, which suppresses skin phagocytosis and reduces tissue permeability, which helps prevent the appearance of skin edema.

KREMGEN. Refers to combined drugs against psoriasis, which effectively relieves the skin of itching and allergies. When applied (on the elbows, knees, soles of the feet and other parts of the body), there is a warning of oxygen starvation of the skin.

The following skin care products are no less popular:

  • Mesoderm, Uniderm;
  • Betaderm, Triderm, etc.

As a rule, CREAMS are prescribed for the treatment of the initial stage of psoriasis, and with obvious symptoms of psoriasis, special ointments for the skin are most often prescribed.

OINTMENT. External means for the skin in the form of ointments, which are prescribed against psoriasis, are divided into 2 groups:

  • non-hormonal;
  • hormonal.

Non-hormonal - have a mild effect on the patient, in contrast to hormonal treatment, which quickly relieves the symptoms of psoriasis on the skin. However, glucocorticosteroids can be addictive with long-term use, as well as many side effects.

1. Hormonal ointments. Glucocorticosteroid preparations contain various active substances, on which their medicinal properties depend.

  • The group of drugs for the development of psoriasis containing mometasone (glucocorticosteroid) includes: Avecort, Nasonex, Uniderm, Monovo, Elocom and Silkaren.
  • Betamethasone group: Betazone, Betasalik, Diprospan, Akriderm, Vipsogal and Flosteron.
  • Flumethasones: Locasalen, Locacorten, Lorinden, etc.

  • Ultralan series: Fluocortolone, Flunitsar, Sinaflan, Synoderm.
  • Triamcinolone: ​​Kenacort, Fluorocort, Polcortolone, Phtoderm, Nazacort.
  • Hydrocortisones: Laticort, Hyoxysone, Sibicort and Oxycort, hydrocortisone ointment.
  • Clobetasol series: Dermoveit, Cloveit, drug Pouecort, etc.
  • Budesonides: Apulein, Pulmicort suspension.
  • Triamcinolones: Berlicort, Kenalog, Nazarcort, Triacort and Fluorocort.
  • These drugs are used in the development of inflammatory processes.

The most effective drugs for psoriasis are the FIRST 3 GROUPS of glucocorticosteroids.

Reviews of experts warn that it is impossible to use a medicinal steroid drug for a long time, as this can cause atrophic changes in the skin. In addition, it is especially important to know the active substance that is part of the drug for patients with individual sensitivity to its components.

2. Non-hormonal ointments. The advantage of non-hormonal ointments in the fight against external manifestations of psoriasis is safety.

Most often used:

  • Zinc and Salicylic ointment;
  • Daivobet and Akrustal;

  • Kartalin and Belosalik.

However, it should be noted that non-hormonal drugs for psoriasis are much longer and weaker to cope with skin problems.

GELI. There are several types of gels against psoriasis:

  • hormonal - Flucinar;
  • combined - Ksamiol;
  • homeopathic - Psoril with tar;
  • with Panthenol - Bepanthen;
  • antihistamines - Fenistil;
  • cosmetic with herbal ingredients - Zosterin, etc.

As a rule, gels are prescribed to neutralize the symptoms of psoriasis on open areas of the skin (on the elbows, hands, etc.).

Gel remedies for psoriasis are prescribed for use with:

  • psoriasis vulgaris of the skin;
  • pustular form of psoriasis;
  • with psoriasis of the scalp;

  • nail psoriasis;
  • articular forms of psoriasis.

The therapeutic effect of gels is explained by the gel base covering the affected areas of the skin, which has a beneficial effect on the patient's skin.

SPRAYS. These remedies are prescribed for the regular treatment of psoriatic rashes on the body and are most effective during remission of psoriasis. Despite the fact that there are no steroid components in the sprays, they have a good anti-psoriatic effect.

Most often assigned:

  • Skin Cap (suppressing fungal growth, especially on the scalp);
  • Spray 999 (indicated for the treatment of psoriatic plaques on the body).

An aerosol drug for psoriasis is convenient because it does not leave behind a greasy sheen and traces of use on clothes.

OILS. Together with drugs in the treatment of psoriatic manifestations on the skin, oils are widely used. This direction in the treatment of psoriasis is not new. Since ancient times, traditional healers have used natural oils as a therapeutic effect on the skin.

During the period of exacerbation against psoriasis, 2 groups of oils are used:

1. Essential: bergamot, oregano, jasmine, chamomile, cedar, lavender, tea tree, cumin, mint.

These oils are most often prescribed in the general complex of antipsoriatic therapy.

2. Food. From psoriatic symptoms at home, edible oils help, which well eliminate the inflammatory process, relieve skin irritation and accelerate regenerative processes.

These oils include: olive, linseed, burdock.

Most often at home, with lesions of the scalp, burdock and olive oil are used, as they help improve blood circulation and restore damaged hair follicles.

SHAMPOO. In addition to oils, shampoos are of great importance in the complex therapy of scalp psoriasis. In this case, both traditional (with the addition of tar) shampoos and new drugs can be used.

Types of shampoos:

  • Tar. They contain tar (from juniper, birch and pine). The tar group of shampoos includes Tana, Algopiks, 911 tar, Friderm Tar. Such shampoos effectively neutralize the itching on the head.
  • Antifungal. These shampoos additionally contain antimycotic components. The active ingredient in these drugs is ketoconazole. The most popular include Vichy, Keto Plus, Nizoral, Bioderma, Squafan. The disadvantages of shampoos include the possibility of increased itching during the first applications.
  • Therapeutic. These include shampoos with salicyl, urea, ichthyol and zinc, which have an antimycotic effect. This category includes Libriderm, Etrivex, Skin-Cap.

  • Cosmetic. Such shampoos have a healing effect on the affected area of ​​the skin of the scalp, preventing its dryness. Effective cosmetic shampoos include Sulsena, Natura and Friderm Balance.
  • Baby. Due to the absence of various chemical additives in shampoos for children from psoriatic manifestations, they are ideal treatments. The most popular are Nipp and Baby Johnsons.

Use of sea salt

Salt has a positive effect, which has a healing effect on all parts of the body. A good effect of the use of salt is observed with psoriatic symptoms of nails and damage to the joints on the arms and legs.

Salt is used in the form of therapeutic baths (1 kg per 2 liters of boiling water), which are taken no more than 20 minutes 3 r. within 7 days. Salt solution has a relaxing effect on the patient's body, accelerates regenerative processes, improves the structure of nails and neutralizes psoriatic manifestations in the joints.

It should be remembered that even such a seemingly safe remedy as salt may have restrictions for use in hypertension and heart disease.

Medical plasters

The composition of therapeutic plasters includes oils (camphor and eucalyptus), methyl salicylates, fluocyanide, borneol. Adhesive plasters are designed to remove psoriatic plaques (especially on the elbows) at home. They have a regenerating, anti-inflammatory and anti-allergic effect on the patient's body. According to experts, it was patches against psoriasis that were most in demand among patients in 2015-2016.

New drugs ("Delicate Skin" and "Quiannaide Xinmeisu Tegao") used in the complex treatment of skin psoriasis are called "plaque killers" in medical practice, since they suppress the activity of epidermal cells.

Medicines for oral use

Medications for oral administration, as a rule, are prescribed only in the complex therapy of the disease.

Such medicines are divided into groups:

  • antihistamines;
  • homeopathic
  • antibiotics;
  • enterosorbents;
  • immunosuppressive agents;
  • vitamin preparations.

Each group of drugs against psoriasis is characterized by certain properties of the impact on the patient's body.

I. HOMEOPATIC PREPARATIONS. Homeopathic remedies are widely used against psoriasis.

The list of drugs includes:

  • Psoriaten (ointment) and Psorinoheel - are administered orally for all forms of psoriasis;
  • Formicicum acidum - is prescribed for serious complications in all parts of the body (on the elbows, knees, etc.);
  • Album arsenicum - the drug is effective for abundant fine-lamellar peeling of the skin;
  • Yodatum arsenicum - is prescribed for weakened and elderly patients;

  • Hydrocolitis - a drug is prescribed to get rid of severe peeling on the body;
  • Calcarea carbonica - used for coarsening of psoriatic plaques on the skin and nail fungus;
  • Manganum - is prescribed for the treatment of joints on the elbows and knees;
  • Petroleum - a drug that restores the structure of nails well.

Homeopathic medicines are selected individually, based on the patient's condition - this is the main condition for the effectiveness of homeopathy.

II. ANTIHISTAMINS. This pharmacological group is prescribed for severe itching, swelling of the skin and allergic reactions.

These include:

  • Claritin, Diazolin;
  • Zyrtec, Suprastin;
  • Loratadine, Erius, etc.

In addition to antipruritic action, antihistamines can have a slight sedative effect, normalizing the patient's sleep.

III. HEPATOPROTECTORS. They can be prescribed to the patient with concomitant complications of psoriasis in the form of disorders of the gastrointestinal tract.

The most popular hepatoprotectors are:

  • Essentiale and Likopid tablets;

  • drug Carsil and Silimar.

The medicinal preparation Likopid deserves special attention, which, in addition to the hepatoprotective properties, has an immunomodulatory effect, due to which it stands out from all the drugs in this group.

IV. ANTIBIOTICS. They are prescribed for the development of psoriasis, as a last resort, when psoriasis is complicated by the acute development of infectious processes.

Your doctor may prescribe the following antibiotics:

  • Penicillin series (Amoxicillin);
  • Macrolide (Erythromycin);
  • Cephalosporin (Cefazolin).

It is important to consider that any form of antibiotics is prescribed for admission after a medical consultation.

V. VITAMIN COMPLEXES. Vitamins and trace elements are present in the body of every person. They help restore the functionality of the immune system and contribute to the overall health of the body.

To get rid of psoriasis, the following vitamin complexes are suitable:

  • Decamevit and Complivit;
  • Undevit, Gegsavit and Revit.

In addition, vitamin preparations of groups E and A, which are included in Aevit, are prescribed for mandatory consumption. In an independent form, vitamin A is included in Retinol, and E - in Alpha-tocopherol. Vitamin complexes have a positive effect on lipid metabolism, improve the structure of nails, and metabolic processes. A course of vitamin therapy is recommended to be carried out 2 times a year.

VI. SORBENTS. When neutralizing psoriasis, the timely removal of toxic substances from the patient's body, which most often accumulate in the gastrointestinal tract, is of no small importance.

For the rapid removal of toxins in psoriasis, enterosorbents are prescribed (Activated carbon tablets, Enterosgel, Polysorb and Polypefan tablets).

The use of these drugs for psoriasis is prescribed not only for exacerbation, but also in complex therapy.

VII. IMMUNOSUPRESSORS (cytostatics). The effective action of these drugs depends on the cytostatic effect on the cellular composition of the lymphoid system. The best known immunosuppressant is Methotrexate. However, its use is limited by high toxicity and many side effects (hepatitis, headache, vomiting, kidney failure, etc.).

Sandimmun (Cyclosporin-A) is considered a more benign immunosuppressant. Therapy with Sandimmun is carried out only in a hospital for 6-7 weeks. If the patient tolerates such therapy well, then the course is repeated 2 times. in year.

To improve cellular respiration and general detoxification of the body, an infusion solution of Reamberin, the active component of which is succinic acid, can be prescribed.

Despite the conflicting opinions of experts, one of the most effective drugs for psoriasis from the group of antistatic drugs is the long-acting hormonal drug Diprospan. Its effectiveness is explained by the active ingredients, but due to the severe consequences, Diprospan is prescribed only against forms such as psoriatic arthritis, erythroderma and pustular psoriasis.

Genetically engineered biological preparations

The latest drugs for targeted psoriasis (Secukinumab, Ixekizumab, Netakimab). They very selectively block key links in the development of the disease and are considered targeted drugs. In the case of IL-17 inhibitors, only IL-17a is blocked, without affecting other immune processes in the body. Genetically engineered biological preparations (GEBP) are prescribed for:

  • severe form of psoriasis;
  • moderate form of psoriasis;
  • nail damage;
  • joint damage;
  • psoriasis of problem localizations;
  • significant deterioration in the quality of life.

Genetically engineered biologics are effective in treating psoriasis, but they involve long-term permanent treatment. Subject to a clear schedule for the use of such drugs, psoriasis goes into stable remission, and as long as the patient follows these rules, the disease does not return.

Biologics for psoriasis

Biological drugs (Enbrel, Remicade) are used for severe forms of psoriasis. Biological products are administered by infusion and block the negative reaction of the immune system.

Biological therapies are used quite rarely and show good results, but their cost is very high, which prevents mass use.

In addition, the possibility of negative manifestations is not fully understood, and many scientists believe that such drugs for psoriasis may increase the risk of developing malignant neoplasms of the skin.

Folk remedies for the treatment of psoriasis

Folk remedies were used long before the advent of traditional medicine. Psoriasis has long been considered a “cursed” disease and healers treated it secretly, at home, with the strictest secrecy. And even now, despite well-developed medicine, folk recipes have not lost their relevance, primarily because such methods of treatment are due to the action of medicinal herbs.

To get rid of psoriasis, the following recipes are used:

  • at home, you can prepare a warm bath with celandine. To do this, take 3 tbsp. ground celandine and pour them 0.5 liters. boiling water, then strain and add to the water prepared for bathing;
  • very often, folk healers use a mixture of Kalanchoe juice (10 g), honey (10 g) and eucalyptus oil (30 g). All ingredients are mixed and the resulting solution lubricates the skin 2-3 times a day;
  • with psoriasis of the elbows and the palmar-plantar form at home, you can use kombucha to relieve the inflammatory process on the skin. To do this, hands or feet are lowered into the solution with kombucha 1 hour before bedtime for 30-40 seconds, and then they wait (without wiping) until they dry themselves;

  • for oral use at home, you can prepare a decoction of bay leaves. For this 20 gr. broken bay leaves are brewed 2 tbsp. boiling water for 10 minutes, after which the solution is filtered and taken 3 times a day for ½ tbsp. in a week;
  • at home, against psoriasis, a decoction of burdock and dandelion roots (1 tbsp each), which are poured with 1 tbsp, is effective. boiling water and kept on fire for 7-10 minutes. After filtering, it is recommended to take a warm decoction of 100 ml. 3 p. in a day.

Despite the fact that folk methods of getting rid of psoriasis are considered safe, you should consult with your doctor before using them.

Medicines for psoriasis from China

The years 2015-2016 are characterized by the great popularity of drugs from China to neutralize psoriatic symptoms on the skin, which corresponds to all modern achievements in pharmacology. Chinese medicine is famous for its approach to the treatment of diseases, which is primarily aimed at activating the body's resources. To date, many medicines from China are used for psoriasis.

The best of them:

OINTMENT "KING OF SKIN". The composition of this drug from China includes ket eye nazol and clobetasol propionate, and additional components of the drug in the development of psoriasis are ingredients of plant origin (kachari, turmeric, sandalwood, etc.).

The drug (ointment) from China has anti-inflammatory, immunosuppressive and anti-allergic effects. It is recommended for use against moderate psoriatic manifestations and fungal infections of the nails.

"PSORIASIS CREAM". The composition of the medicinal cream includes components such as sophora, pearl powder and ostchol. This drug from China has a calming and anti-inflammatory effect, relieving skin irritations, including psoriatic manifestations on the hands and feet. The maximum effectiveness of the drug is observed with continuous use for 7 days. In addition, the advantage of this group of drugs is their ability to use on the skin at home.

LOTION "FUFAN". One of the most popular drugs from China today. It contains acids (salicylic and fluoric), as well as borneol.

Salicylic acid prevents the development of fungal infections, including the nail area. Fluoric acid neutralizes the pathological process on the skin. Borneol has a cooling and analgesic effect on the skin affected by psoriasis.

In addition, Fufan promotes rapid regeneration of skin tissues and enhances local immunity. The lotion can be used all over the body, as well as on the scalp. "Fufan" softens the keratinized parts of the skin well, absorbs as much as possible, leaving no marks on clothes.

Fufan helps to normalize blood circulation in the affected part of the body, preventing secondary infection of the skin, and can be used at home.

It is important to consider that "Fufan" cannot be used on large areas of the skin, and you should also avoid getting the lotion on the mucous membranes and the wound surface, because "Fufan" can prolong the healing time of the skin wound.

XIAOYIN TABLETS. Chinese tablets consist of parsnip, sophora, angelica, boletus, peony, and honeysuckle. The pharmacological properties of the drug are determined by the combined effect of herbal preparations on the skin.

Tablets are recommended to be taken in complex therapy, as they have a weak therapeutic effect against psoriatic manifestations on the skin. "Xiaoyin" has no side effects and can be taken even in children.

A feature of antipsoriatic drugs for getting rid of psoriasis from China is their natural composition and the complete absence of chemicals. As a rule, they have a minimum number of contraindications and side effects, which makes psoriasis therapy as safe as possible.

It should be borne in mind that all medicines, including Chinese drugs, should not be used without first consulting a doctor. Only a highly qualified specialist can find out which medicines are suitable for the patient, taking into account the characteristics of the body and the course of psoriasis.

New treatments for psoriasis developed every year. Among those that are just appearing in Russia: ultraviolet treatment (laser and UV rays 311 nm), the Goekerman method, blood hemocorrection, monoclones Brodalumab and Cosentix. Consider their advantages and prospects.

UV treatment (phototherapy)

The method has been widely used in Europe since the 1960s. In Russia, phototherapy is just emerging and gaining popularity. Its main merit is no side effects and safety. Ultraviolet treatment is approved by the Ministry of Health and is included in the state standard for the treatment of patients with psoriasis. However, it is not yet very common. Let's consider two new types of phototherapy for Russian medicine.

Narrow Band UVB Therapy

Device for the treatment of psoriasis with ultraviolet light

Treatment with long-range narrow-band UVB therapy works at the cellular level. With this method, it is this peak of activity that is most beneficial for skin diseases.

Excimer laser treatment

excimer laser

The excimer laser has a wavelength of 308 nm and acts narrowly. The irradiation area is only 3x3 cm. It is well suited for patients with limited forms of psoriasis, with single small spots.

The method is not yet widespread in Russia, especially in the regions, due to the high cost of equipment. To treat with an excimer laser, the doctor must have special qualifications and a high level of professional skills.

There are positive reviews about the application of the method on the forum:

Feedback on laser treatment by user manaraska

Goekerman method

The principle of operation of this method is similar to the principle. First, the patient is smeared with coal tar, which enhances susceptibility to ultraviolet light. Then irradiated with a UV-B spectrum lamp (311 nm).

Since the method is relatively new, do not use it yourself, as you need to accurately calculate the doses of ultraviolet and tar. It can be used only in a hospital under the supervision of a doctor.

New generation monoclonal antibodies

Monoclonal antibodies are biological drugs for the treatment of psoriasis and psoriatic arthritis. The essence of the method is to isolate the substances that the body lacks in psoriasis, artificially synthesize and introduce to the patient. These drugs do not suppress the immune system, act only on diseased cells, have high performance (80-90% according to various sources).

Consider new generation drugs.

Brodalumab

Trials of the drug began about 4-5 years ago around the world, including Russia. Tests closed in Russia in June 2015 for unknown reasons (officially - the appearance of suicidal thoughts in patients). However, the effectiveness of the drug is high.

Feedback from a Russian patient with psoriasis who participated in the tests:

Review of laser treatment by user JuliaK

Therefore, the review board of the US Food and Drug Administration (FDA) advocated registration of the drug. How the story will continue is not yet known. The decision on drug registration will be made in November 2016.

Cosentix (secukinamab)

In January 2015, the FDA approved the use of Cosentix, a new generation monoclonal antibody drug. The tool was tested on 2403 patients with moderate and severe psoriasis.

Research is still ongoing in Russia, so no significant performance reviews yet.

Diet and vitamin D

Western scientists conducted a study of the latest method, which involved 9 patients with psoriasis.

For six months, patients received vitamin D3 (dose: 35,000 IU) once a day, followed a diet low in calcium (avoided dairy products, rice, oat, soy milk). As a result all got rid of stains and performance improved.

Scientists attribute this positive experience to the fact that in the body of patients with psoriasis, the synthesis of vitamin D3 is disturbed, as well as the balance of calcium. If they are restored, the skin will return to a healthy state. Read the detailed results of the study in the publication: "Pilot study of the effect of high daily doses of vitamin D3 on the clinical course of psoriasis and vitiligo" (in English).

Surgical treatments for psoriasis

Surgical methods are used in severe forms of psoriasis, because it strong intervention in the body. The essence of these methods is the impact on the blood, the purification of blood and plasma.

Hemocorrection of blood

The essence of the method is to remove unnecessary cells from the vascular bed that affect the disease. Hemocorrection is of several types:

  • monocytapheresis and granulocytapheresis (GMA) - gives a positive result and does not have serious side effects with,;
  • lymphocytapheresis (LfA) gives a result in psoriasis, studied in 5 patients;
  • extracorporeal photopheresis (ECP) - PUVA blood therapy, in which the blood is irradiated directly with ultraviolet radiation. In this case, a photosensitizer (a substance that enhances susceptibility to UV rays) is injected into the blood or taken as a medicine.

Methods of hemocorrection promising However, they are not widely used due to their high cost and technical complexity.

Conclusions on new treatments for psoriasis

Modern medicine knows about 700 ways to treat psoriasis. However, none of them helps absolutely everyone in 100% of cases. Therefore, scientists invent more modern methods, come up with new drugs.

From new treatments for psoriasis and psoriatic arthritis efficient the following:

  1. excimer laser treatment;
  2. Goekerman method - a combination of UV rays 311 nm and tar;
  3. Brodalumab and Cosentix - new generation biological drugs;
  4. a combination of a diet low in calcium and vitamin D3 in high concentration;
  5. blood hemocorrection.

Scientists and patients hope for the discovery of a perfect medicine, a pill that will save you from psoriasis. However, treatment success is only in combination disease, inside and out. To heal from the inside, use . To influence from the outside, many effective means have already been invented: ointment, shampoos. Otherwise, the remission of psoriasis will be short-lived.

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Common chronic dermatosis, which is characterized by scaly plaques and papules, is called psoriasis. A new drug to treat this elusive, multi-faceted ailment is patented every year in the Pharmaceutical Registry.

But, despite the many novelties, the modern treatment of psoriasis has not found a universal remedy.

News in the treatment of psoriasis: internal modern remedies

Cytostatics (Methotrexate) and corticosteroids (Dexamethasone, Prednisolone) - drugs with an extensive list of adverse reactions - have been replaced by glucocorticoid combination drugs. New in psoriasis:

  • betamethasone,
  • betazon,
  • Diprosan

and other new generation drugs effectively stop acute conditions.

Means are administered intramuscularly several times a week with a short treatment course. Short-term - new in the treatment of psoriasis, allows you to reduce adverse reactions to a minimum.

The latest in the treatment of psoriasis: pathogenetic and etiotropic agents

Drugs that destroy a protein that can damage skin cells is an effective novelty of genetic engineering.

Intravenous drugs:

  • etanercept,
  • remicade,
  • Stelara,

belonging to the group of drugs with monoclonal antibodies - the latest in the treatment of psoriasis.

The latest drugs, administered by a dropper into the patient's bloodstream once every few weeks, neutralize the destructive effect of a protein that damages epidermal cells. At the same time, specific protein-antibodies are synthesized in the patient's body, coinciding with human immunoglobulin. Clinical practice has confirmed the high efficiency of a new method of treating psoriasis

But besides this, dermatologists who use modern innovations in their practice noted the following adverse reactions:

the appearance of hematomas on the skin.

  • Depression, accompanied by apathy and drowsiness;
  • Rash, itching;
  • Arrhythmia, instability of blood pressure;
  • Change in blood composition;
  • Conjunctivitis, pneumonia with the development of pulmonary edema;
  • Thrombophlebitis, nosebleeds due to bleeding disorders,

Psoriasis News: Local Remedies

1 . Psorkutan- a modern effective drug.

Calcipotrile (active substance) is an analogue of D3-vitamin, which is an active metabolite. The drug applied to the skin, interacting with the cells of the epidermis,

  • suppresses pathological cell division,
  • stops the process of inflammation,
  • has an immunocorrective effect.

Psorkutan does not cause:

  • skin atrophy,
  • relapse after discontinuation of the remedy,
  • combines well with PUVA therapy, which cannot be said about earlier generation glucocorticoids.

2 .Elokom and Advantan- non-halogenated ointment preparations belonging to the fourth group of glucocorticoid agents. Available in the form of a cream, emulsion, ointment. Applying novelties in treatment, patients manage to avoid a number of adverse reactions that are often observed when using other glucocorticoids.

The absence of components such as chlorine and fluorine in the composition of the funds allows you to prescribe Ecol and Advant in the form of an ointment, emulsion, cream to elderly patients and children.

3 . Active substance Dithranol has a pronounced anti-inflammatory effect. Suppresses inflammation and the process of reproduction of histio and hematogenous cells in it.

  • psorax,
  • Cygnoderm,
  • Cygnolin,

Novelties from psoriasis containing Dithranol.

The course of treatment is from two weeks to two months. Improvements are observed in 70% of patients. The duration of therapy and the method (long-term or short-term) are selected by the attending dermatologist.

Itching, swelling and redness (erythema) at the site of application are side effects that may occur.