Monulela Analogs Cheaper. Domestic and overseas monural substitutes

  • Date: 19.10.2019

This page provides a list of all the analogues of the monulela in composition and indication to use. A list of cheap analogues, and also be able to compare prices in pharmacies.

  • The cheapest analogue of the monural:
  • The most popular analogue of the monural:
  • ATX Classification: Phosphomycin
  • Existing substances / Composition: phosphomycin

Cheap analogues of MONURAL

When calculating the cost cheap analogs of monural Considered the minimum price, which was found in the price list provided by pharmacies

Popular analogues of MONURAL

The list of drug analogues Based on the statistics of the most requested drugs

All analogues of MONURAL

Analogs in composition and indication

Name Price in Russia Price in Ukraine
phosphomycin -- --
phosphomycin 10500 rubles 484 UAH
phosphomycin -- 134 UAH
phosphomycin 118 rubles 42 UAH
phosphomycin 2100 rubles --
phosphomycin -- 158 UAH
phosphomycin 352 rubles 96 UAH
phosphomycin 122 rubles --
phosphomycin -- 288 UAH

The above list of the analogues of the drugs in which are indicated replays of monuralis the most appropriate because they have the same composition of the active ingredients and coincide the indication to use

Analogs in the indication and method of application

Name Price in Russia Price in Ukraine
262 rubles 295 UAH
bacteriophages -- --
bacteriophages 834 rubles --
bacteriophages -- 89 UAH
bacteriophages -- --
Dioxidin -- --
dioxidine, Lidocaine -- 33 UAH
Spectinomycin 263 rubles 47 UAH
Spectinomycin -- 77 UAH
glyceril Trinitrath -- 78 UAH
Nitroxoline 27 rubles 2 UAH
Nitroxoline 172 rubles 117 UAH
Nitroxoline -- --
Nitroxoline -- 1 UAH
Linezolid 4 rubles 704 UAH
Linezolid -- 669 UAH
Linezolid -- 522 UAH
Linezolid -- 782 UAH
Linezolid -- 194 UAH
Linezolid -- --
Linezolid -- 430 UAH
Linezolid -- --
Linezolid 5900 rubles --
Linezolid 141 rubles --
Linezolid -- --
Linezolid -- --
Daptomycin 347 rubles 2326 UAH
Tetzolid 4500 rubles --
Dioxidin 12 rubles 7 UAH

Different composition, may coincide due to the indication and method of application

Name Price in Russia Price in Ukraine
45 rubles 111 UAH
Vancomycin -- 124 UAH
36 rubles --
Vancomycin 5800 rubles 297 UAH
Vancomycin -- --
Vancomycin -- --
Vancomycin -- 157 UAH
Vancomycin -- --
Vancomycin -- 97 UAH
Vancomycin -- --
Vancomycin -- --
Vancomycin 141 rubles --
Vancomycin -- --
Teicoplan -- 339 UAH
Teicoplan 3580 rubles 577 UAH
Teicoplan -- --
Teicoplan -- 361 UAH
Televancin -- --
sodium colorsmetat -- 340 UAH
sodium colorsmetat 590 rubles 2832 UAH
Polymixin B. -- --
Polymixin B. -- --
sodium fusidat -- --
Tenonitrosol 320 rubles 87 UAH
Metronidazole. -- 7 UAH
Metronidazole. -- --
Metronidazole. 7 rubles 10 UAH
Metronidazole. 10 rubles 5 UAH
Metronidazole. 64 rubles 23 UAH
Metronidazole. -- 16 UAH
Metronidazole. -- --
Metronidazole. -- 14 UAH
Metronidazole. -- 17 UAH
Metronidazole. -- 10 UAH
Metronidazole. -- --
Metronidazole. -- --
Tinidazole. 28 rubles 10 UAH
Tinidazole. -- 29 UAH
tinidazole, MCC, Crospovidon, Corn Starch, Magnesium Stearat -- --
Ornidazole. -- 58 UAH
Ornidazole. -- 47 UAH
Ornidazole. -- 34 UAH
Ornidazole. 12 rubles 17 UAH
Ornidazole. -- 37 UAH
Ornidazole. 45 rubles --
Ornidazole. -- 49 UAH
Ornidazole. -- 44 UAH
Ornidazole. -- --
Ornidazole. -- --
Ornidazole. -- 35 UAH
Ornidazole. -- 71 UAH
Ornidazole. -- --
Ornidazole. -- 44 UAH
Ornidazole. -- 92 UAH
Ornidazole. -- --
Ornidazole. 159 rubles 150 UAH
Ornidazole. -- --
Nitrofurantoin 16 rubles 25 UAH
Nitrofurantoin 45 rubles --
Furazidin 20 rubles 12 UAH
Furazidin 240 rubles 8 UAH
Furazidin 441 rubles 8 UAH
Furazidin 317 rubles --
Furazidin 258 rubles 63 UAH

To compile a list of cheap analogues of expensive drugs, we use prices that we provide more than 10,000 pharmacies throughout Russia. The database of drugs and their analogues is updated daily, so the information provided on our site is always relevant as of the current day. If you have not found an analog you are interested in, please use the search above and select the medicine youest interest from the list. On the page of each of them you will find all the possible options for the analogues of the search drug, as well as the prices and addresses of pharmacies in which it is in stock.

How to find a cheap analogue of dear medicine?

To find an inexpensive analogue of medicine, generic or synonym, forward the queue, we recommend paying attention to the composition, namely the same active substances and indications for use. The same drug actors will indicate that the drug is a synonym for a drug, a pharmaceutically equivalent or pharmaceutical alternative. However, do not forget about the inactive components of similar drugs that can affect safety and efficiency. Do not forget about the instruction of doctors, self-medication can harm your health, so before the drafting of any medical drug always consult your doctor.

Monulela Price

In the sites below you can find prices for monural and learn about the presence in the pharmacy nearby

  • Description.
    White granules with mandarine smell.

    Pharmacotherapeutic groupantibiotic

    ATX code J01XX01 .

    Pharmacological properties
    Pharmacodynamics
    The active substance of MONURAL® - phosphomycin thrometamol is a wide spectrum antibiotic, a derivative of phosphonic acid.
    Montural® has a bactericidal action. The mechanism of action is associated with the suppression of the first phase of the synthesis of the cell wall of the bacteria. Being a structural analogue of phosphoanol Piruvata, competing with the enzyme N-acetyl-glucosamino-3-o-entompius-transferase, resulting in a specific, selective and irreversible inhibition of this enzyme, which ensures the absence of cross-resistance with other classes of antibiotics and the possibility Synergism with other antibiotics (in vitro notes synergism with amoxicillin, cephalexin, pepehemidine acid). Fosfomycin trometamol spectrum antibacterial in vitro action includes the most common gram-positive (Enterococcus spp., Enterococcus faecalis, Staphylococcus aureus, Staphylococcus saprophyt., Staphylococcus spp.) And gram negative (E. coli, Citrobacter spp., Enterobacter spp., Klebsiella spp., Klebsiella PNEUMONIEE, MORGANELLA MORGANII, PROTEUS MIRABILIS, PSEUDOMONAS SPP., SERRATIA SPP.) Paths. In vitro phosphomycin Trometamol reduces the adhesion of a number of bacteria on the epithelium of the urinary tract.

    Pharmacokinetics
    Suction: Monulela® is quickly absorbed from the gastrointestinal tract during oral administration.
    In the body dissociates phosphomycin and thrometamol. The latter does not have antibacterial properties. Bioavailability in one-time dose of 3 g is from 34 to 65%. The maximum plasma concentration is observed in 2-2.5 hours after oral administration and is 22-32 mg / l. The half-life of plasma is 4 o'clock.
    Distribution: MONURAL® is not associated with plasma proteins, not metabolized, preferably accumulates in the urine. With oral administration of a single dose of 3 g in the urine, a high concentration is achieved (from 1053 to 4415 mg / l), by 99% bactericidal for most conventional pathogens of urinary tract infections. The minimum inhibitory concentration of MONURAL® for these pathogens is 128 mg / l. It is maintained in the urine for 24-48 hours, which implies a monoco treatment. Concentration of MONULAL® in the urine above the minimum overwhelming concentration for E. coli is maintained at least for 80 hours.
    EXTENSION: MONURAL® is 90% excreted by kidneys unchanged with the creation of high concentrations in the urine. About 10% of the adopted dose is excreted through the intestines unchanged. In patients with a moderate decrease in renal function (creatinine clearance< 80 мил/мин), включая ее физиологическое снижение у лиц пожилого возраста, период полувыведения фосфомицина немного удлиняется, но концентрация в моче остается на терапевтическом уровне.

    Indications for use
    · Acute bacterial cystitis, sharp attacks of recurrent bacterial cystitis;
    · Bacterial nonspecific urethritis;
    · Asymptomatic massive bacteriuria in pregnant women;
    · Postoperative urinary tract infections;
    · Prevention of urinary tract infection during surgical intervention and transurethral diagnostic studies.

    Contraindications
    Individual increased sensitivity to phosphomycin thrometamol, severe renal failure (Creatinine clearance

    Application during pregnancy and lactation
    During pregnancy, the drug is prescribed only when the potential benefit for the mother exceeds the potential risk to the fetus.
    If necessary, prescribing a drug during lactation should be stopped breastfeeding during treatment

    Method of application and dose
    Inside.
    Granules are dissolved in 1/3 glasses of water. Montural® is used once a day inside an empty stomach 2 hours before or after meals, preferably before bedtime, pre-emptying the bladder.
    AdultsNews 1 package (3 g) 1 time per day.
    In order to prevent the infection of urinary tracts in surgical intervention, transurethral diagnostic procedures are taken by MONURAL® twice in the doses indicated above: 3 hours before intervention and 24 hours after the intervention.
    Children from 5 years to 18 years old are prescribed in a daily dose of 2 g 1 time per day.
    The course of treatment is 1 day.
    In more severe cases (Elderly patients, recurrent infections) take another 1 package after 24 hours.
    In renal failure, reduce the dose and extend the intervals between the introductions.

    Side effect
    Disorders are possible from the gastrointestinal tract (nausea, heartburn, diarrhea), skin rash, allergic reactions.

    Overdose
    Symptoms of overdose: diarrhea. In the occurrence of persistent diarrhea, symptomatic treatment is recommended.
    The risk of overdose is minimal, since MONURAL® is available in a package of 1 or 2 packages. In the case of an overdose, it is recommended to receive fluid inwards in order to increase the diurea.

    Interaction with other drugs
    Simultaneous reception with metoclopramide should be avoided, as this may lead to a decrease in the concentration of monulela® in serum and in the urine.

    special instructions
    Simultaneous meal slows down the absorption of Montoural® - it is necessary to apply the drug 2 hours before or after meals.
    Sick diabetes mellitus should be taken into account that in 1 MONURAL® package with dosage 2 g or 3 g of phosphomycin contain 2,100 g or 2.213 g of sucrose, respectively.

    Form release
    Granules for the preparation of a solution for intakes inward 2 g and 3 g
    Almost 6 g or 8 g of the drug are placed in packages of 4 layer laminated foil (Paper-polyethylene-aluminum-polyethylene). 1 or 2 packages are placed in a cardboard pack along with instructions for use.

    Storage conditions
    List of b. Hand at a temperature not higher than 30 ºС.
    Store in places inaccessible to children.

    Shelf life
    3 years.
    Do not use the expiration date specified on the package.

    Conditions of vacation from pharmacies
    On prescription.

    Manufacturer
    Zampon Svitserland Co., Ltd.,
    VIA Industry 13, CH-6814 Cadampino, Switzerland.

    All information is provided for informational purposes and is not a reason to independently appoint or replace medication.

Monulela as the drug of large bactericidal exposure is actively struggling with the pathogens of many diseases. Activity phosphomycin has a pronounced antibacterial effect. Released form: Granules for the preparation of the solution.

Scope of the drug: Treatment of acute bacterial cystitis, urethritis of non-specific form, massive bacteria, prevention of postoperative rehabilitation. Restrictions on reception: an allergic rash, kidney dysfunction, children's category up to 5 years. Middle rates 520-550 rubles.

Analogs of Russian production

Domestic manufacturers are cheap analogs of the drug, which allows you to easily choose the necessary medicine. The main prototypes are defined in the following table.

Prototype Price in Rubble Description
Bacteriophage number 690–700 Qualitative synonym for a monuleur. It has the appearance of a yellow mortar. The application area is therapy of bacterial pathologies of different shapes.

High sensitivity in relation to the main composition is contraindicated.

Calcex. 35–50 The cheapest counterpart of the monulela represented by the Russian manufacturer. Tablets special form.

Used as prevention with infectious type pathologies.

Nitroxoline 60–100 The cheap monulela substitute is made in the form of white tablets. The active connection of nitroxoline provides the bactericidal nature of the influence.

Actively prescribed in cystitis of various forms, other pathologies of the urogenital system.

It is forbidden during the period of tooling the child, the lactation feeding, the development of cataracts, the absence of the liver, kidneys.

Phosphocin 200–220 Inexpensive prototype of the original. It has the form of soluble granules for the manufacture of the solution.

The composition of the medication is based on the content of the current compound and ensures its effectiveness.

Designed for therapy of uncomplicated pathologies of the urogenital system.

Contraindications: conducting hemodialysis, allergic rashes, age limit up to 12 years.

Urofosfabol 100–170 A decent replacement for the cheap analogue of a monulela. Powder for preparing a solution of green color.

Effective with systemic treatment of antimicrobial diseases.

Ukrainian substitutes

Representatives of the Ukrainian Medical Industry contain in the asset inexpensive and high-quality analogues of the Montoural in various form of release.

Detailed consideration in the following list:

  • Dioxidin. One of the inexpensive analogues of the original Ukrainian production. It is represented as a powder for the preparation of the solution. The active ingredient ensures the antimicrobial nature of the origin of the medication.

    Indications for use: purulent infectious pathologies of various etiology. Not recommended for severe sensitivity. Average rates of 300-320 rubles.

  • Dioxisol. Synonym for a melanaly cheaper. Available in the form of a solution and is used in the treatment of antibacterial diseases.

    It has a number of contraindications: bradycardia, arterial hypertension, cardiogenic shock, allergic to the main components, lack of adrenal gland bark. Middle rates 110-115 rubles.

  • URRSOLIN. The cheapest prototype. Tablets special form. Antimicrobial means for systemic treatment. Used with a simple flow of urinary flows.

    The drug is prohibited by violation of the liver, kidney, allergies. Middle rates are 10-30 rubles.

  • Urofoscin. An effective drug of antibacterial action. Phosphomycin destroys causative agents in the development of pathological infectious diseases of different types.

    It is necessary to eliminate the use of hemodialysis, liver, kidney dysfunction, allergies, children under 12 years old. Middle rates 200-250 rubles.

  • Cystoral. The inexpensive prototype presented as granules for internal use. The active compound is a natural antimicrobial agent.

    Acts with acute flow of light urinary infections. High sensitivity, allergic typical rashes, hemodialysis, children's category up to 12 years are contraindicated to the appointment. Middle rates 350-400 rubles.

Belarusian generics

Preparations of Belarusian production do not provide analogues that have the same structure of the medication, but among them you can choose several drugs of similar action.

Table of close generics:

Prototype Price in Rubble Description
Doxycycline 500–600 Antibiotic action preparation. Relative analogue of a monulela. Scope of various infectious manifestations.

Contraindications: tooling a child, lactation feeding, lack of work of the liver, kidneys, age category up to 8 years.

Cephalexin 300–380 Cheap analogue of Belarusian production. Solution for enclosures.

Indications for appointment: Treatment of infectious pathologies of various etiology.

Cystivit 200–220 Analogue of the Montoural cheaper. Effective in the acute flow of infectious inflammatory processes of the urogenital system.

Taking medication during pregnancy, lactation diet, allergic processes, age limits up to 12 years old.

Analogs of foreign production

A modern series of imported drugs with similar action with a monuleur has a large number of positive qualities and relatively low cost.

List of famous original substitutes:

  1. Kirin. Synonym for a monulela produced as an antibiotic tricyclic row. The active combination of spectinomycin has a pronounced antibacterial effect and is prescribed for the treatment of infections of the genitourinary system.
  2. Lizomak 600.. The best monulela analogue produced by imported pharmacists. Presented in the form of tablets covered with a shell. Used in the treatment and prevention of bacterial infections of various shapes.

    Contraindications: Increased sensitivity, arterial hypertension, thyrotoxicosis, aggravation of schizophrenia. Middle rates 1300-1400 rubles.

  3. 5-NOC. Close prototype of the original, produced in the form of tablets. Nitroxoline guarantees bactericidity of the drug. Effective in the acute flow of pathological infections of the urogenital system.

    Do not use medicine when carrying a baby, lactation feeding, renal, liver failure. Middle rates 250-270 rubles.

  4. Phosmural. Effective antimicrobial preparation for systemic treatment of urinary infections.

    The composition of the drug is based on the action of phosphomycin component having an antibacterial effect.

    High sensitivity with respect to the current compound is an exception to the application. Middle rates 400-450 rubles.

Summing up implies a description of all characterizing the qualities of the drug showing its effectiveness. The medicine has a sufficient number of decent and inexpensive analogues.

Before deciding how to replace a monulela should be consulted by a qualified physician, which will bring a positive effect of the use of medication!

    Related records

Wide spectrum of action. The purpose of the defeat - infections of urinary and sex tract. The tool has many positive feedback. Essential minus funds - its price. She is from the "biting" squad. Therefore, the article will tell about the "monural", analogues that correspond to the effectiveness of the drug, as well as about prices and reviews.

The second part of the article will be devoted to the drug "Nolysin". It is often mistakenly considered an analogue of "Montural". Why wrong? You will learn about it below.

Briefly about the preparation

"MONURAL" is an antimicrobial drug (and simply speaking - an antibiotic) of a wide range of action. The main active ingredient is phosphomycin - affects most gram-positive and gram-negative bacteria (enterococci and streptococcal, staphylococcus, including golden, klebseyelle and proteis).

It kills these microorganisms and has a distinctive feature that increases its effectiveness. With a single reception of "monural" (analogs of the drug below), in high concentrations persist in the body up to two days, which is sufficient for sterilization and purification of urine, and leads to recovery.

Instruction

This antibiotic is not only quite effectively struggling with pathogenic microorganisms, but also reduces their irritating effects on epithelial tissues, eliminating the organs of the urogenital system, which almost immediately after admission reduces discomfort and pain.

"MONURAL" (analogs of the drug in most too) are produced in the form of granules, in bags. Usually one bag is enough for a course of treatment.

The active ingredient is quickly absorbed by the gastrointestinal tract and excreted by the kidneys is almost unchanged.

Usually adults and children over 12 years old drug is prescribed once - a bag for a day. The granules dissolve in the third part of the water in the glass and drink on an empty stomach, preferably after emptying the bladder.

Indications

  • acute bacterial cystitis;
  • chronic bacterial forms of cystitis with frequent relapses;
  • asymptomatic bacterial infections in pregnant women, when the potential benefits of the drug exceeds the risk for the fetus;
  • bacterial infections of the urinary tract in the postoperative period.

"Monulele" (analogues, the price will be presented below), successfully established itself with this insidious disease can begin completely suddenly and not only cause discomfort and pain, but also to break all the plans of the disease. In this case, the tool very quickly stops symptoms, facilitates pain.

Contraindications and side effects

"Montural" (analogues, reviews about the drug below) has not so many side effects. Contraindications to the use of the means are also minimal.

Individual intolerance to phosphomycin, allergic reactions to the substance are a categorical contraindication to the reception.

"Monural" is contraindicated to children under five, since the tests for this age have not yet been carried out.

Among the side effects, an increased reaction from the skin is most common (rashes and itching are possible), and from the gastrointestinal tract - nausea and heartburn.

Reviews of the preparation

Reviews of "Montoual" in most cases are positive. Patients are satisfied with the effect of the drug. Basically, the means is "ambulance" in the treatment of sharp and chronic cystitis. A big advantage of it is also a form of release and one-time application for one course.

The remedy is quite gently affecting the body without disturbing natural processes, and leads to dysbacteriosis only in rare cases.

"MONURAL": Analogs

Analogue is considered a means with a similar acting substance and, accordingly, international code. At the same time, the pharmaceuticals can significantly differ in the number of the main component, dosage, form of release. Be sure to take into account this by purchasing the analogue of the funds written to you at your own risk. Sometimes the price of the analogue does not justify an uncomfortable form or the worse phase of cleaning the means. At the same time, there are many analogues and generics of famous drugs, according to their quality, no inferior to the original.

"Monulela" analogues in Ukraine has the following:

  • "Fosmural". Means with a similar composition. Produced in India. The action and content in therapeutic doses in the body corresponds to the primigation-origin. Price - about 153 UAH. (505 rubles).
  • "Phosphorah". The drug is also available in granules. Price - 250 UAH. (830 rubles). To maintain the therapeutic effect and cure, the tool is also delayed in the desired amount in the body to two days, eliminating the body from pathogenic bacteria.

"Nolysin": about the preparation

The view is that "Nolysin" is a cheaper "Montural" analogue, erroneously. The tool has a wider range of exposure.

An antibacterial drug with an active substance Norfloxacin is intended for the treatment of urinary tract infections, genital infections, infections caused by gonococcus, bacterial invasions of the gastrointestinal tract, diarrhea of \u200b\u200bbacterial origin.

It acts on the pathogenic microflora by the method of inhibition of protein synthesis, which in turn leads to the death of microorganisms.

Produced in the form of tablets.

Indications for use:

  • Acute uncomplicated cystitis.
  • Chronic bacterial cystitis.
  • Chronic urinary tract infections with frequent relapses.
  • Acute uncomplicated gonococcal infection.
  • Prevention of sepsis in patients with agranulocyte (pathological decrease in blood leukocytes, which leads to increased vulnerability to bacteria and, respectively, infections).

Contraindications and side effects of "Nolysin"

Contraindications for receiving "Nolysin" are pregnancy and breastfeeding, children's age up to 18 years, individual sensitivity and intolerance to the main active substance or components components.

Among the side effects of the drug are given nausea, vomiting, disruption of appetite, anorexia, stool violation. The liver, in turn, can respond to the drug to increase the activity of enzymes.

From the side of the nervous system there is a breakdown of sleep, depressive state, irritability and hallucination. There is also a possibility of a significant reduction in blood pressure, so the drug is not recommended by hypotonized.

"Nolysin" or "Montural"?

Sometimes a wide selection of pharmaceutical preparations causes confusion in an ordinary consumer. If you make a choice in favor of one of these drugs, you should consider several factors.

  1. "Nolysin" has more side effects than "MONURAL". It is more aggressively affecting the microflora.
  2. "Nolysin" is contraindicated in hypotoniki.
  3. "MONURAL" has a narrower range of exposure.

In what cases is it worth to give preference to "Monturalla"? In the treatment of cystitis, the drug has proven itself well, it gently affects the body and is highly efficient.

The effect of "Nolysin" in the treatment of this disease is also proved, but with the ratio of positive and side effects, the use of "Montoulala" is more appropriate.

If we are talking about more serious infections, such as a gonococcal or gastrointestinal tract, then, despite the side effects, it is worth a preference to "nolitsin", since it is more effective in this case.

The human body is a reasonable and fairly balanced mechanism.

Among all the well-known science of infectious diseases, a special place is given to infectious mononucleosis ...

About the disease that official medicine calls "angina region", the world has already been known for a long time.

Pig (scientific name - epidemic vapotitis) is called an infectious disease ...

The hepatic colic is a typical manifestation of gallstone disease.

The edema of the brain is the consequences of excessive loads of the body.

There are no people in the world who have never been sick orvi (acute respiratory viral diseases) ...

A healthy human body is able to assimage as many salts obtained with water and food ...

Burst of the knee joint is a widespread disease among athletes ...

Analogue of a monulela from cystitis

"MONURAL": analogues of domestic. "MONURAL": instructions for use, analogues, reviews

Frequent urination or pain in the lower abdomen may indicate the development of cystitis. Many seek to cure the disease through warming at home. This is categorically impossible to do this. If the disease has a bacterial nature, the elevated temperature will contribute to even greater development of infection. In this case, do not do without antibiotics. Good results in the treatment of cystitis shows the preparation "MONURAL". Domestic analogues are also used. But only a doctor can take a decision on the use of a means.

Medication release form and its composition

The medication refers to the Uroanthisptic group. Available in white tablets with tangerine odor. The main operating component is phosphomycin thrometamol. As auxiliary elements, sucrose, orange flavoring, magnesium stearate are used. Tablets belong to a number of broad spectrum antibiotics. The mechanism is based on the suppression of the synthesis of protein of pathogenic bacteria at the initial stage. Microorganisms cease to multiply and soon die.

The main operating component is active in relation to most gram-positive bacteria. However, the medicine affects the useful microflora of the human body. Therefore, tablets or any substitute "Montural" can only be used as part of complex therapy. Use the medicine without appointing a specialist is undesirable.

Pharmacokinetics

The main current component is quickly absorbed from the gastrointestinal tract after taking inside. Maximum bioavailability is achieved after 2 hours and is about 65%. This indicator can be significantly reduced if the "Montural" tablets are taken during meals. Analogues Domestic are used according to the same scheme.

Phosphomycinet is not associated with blood proteins. To a greater extent, the main acting component of the antibiotic accumulates in the urine. More than 90% of the medication is excreted during the day with a single reception. In patients who have kidney problems, as well as in the elderly, the biodegradability of the medication is significantly reduced. In this case, the duration of the drug removal can be increased to two days.

Indications

Only if the disease has a bacterial nature, the tablets "MONURAL" can be appointed. Instructions for use, analogues, reviews - All these questions are interested in patients. However, recall once again the capital truth: the medicine should recommend a qualified specialist. Most often, the drug is prescribed with acute bacterial cystitis. At the same time, women feel a strong pain at the bottom of the abdomen, the body temperature rises, the amount of urination increases. The doctor conducts a number of analyzes to determine the focus of infection. Tablets "MONURAL", analogues (domestic and foreign) can be applied at home, but most often the therapy passes in the hospital.

The drug can also be appointed with a non-specific urethritis of bacterial nature. At the same time, the medication is part of the complex therapy. Tablets can also be appointed in order to prevent surgery, if it comes to the urinary system. Means "Montural" prevents infection in the bladder.

Pregnant women also can also be assigned a medicine if the estimated benefit for the mother exceeds potential harm to the baby. Very often, women can develop bacteriuria flowing without symptoms. Deviations can be identified only thanks to the analysis of urine.

Sideflines

You should use the tablets "MONURAL". Instructions and analogs of the drug, possible side effects - all this must be studied before the start of therapy. Most often, unpleasant symptoms appear in the case of the use of medication in an increased dosage. First of all, the patient may feel dizziness, noise in the ears, nausea. In rare cases, vomiting occurs. Allergic reactions are also common. Patients may have skin rashes and itching. Analogs of Tablets "MONURAL" can also contribute to the development of side effects, if we take them in an enlarged dosage.

Below will be considered popular domestic analogs of the drug.

"Phosphomycin"

If you find the right drug in the pharmacy failed, you can always choose a qualitative analogue. Popularity of the therapists uses domestic phosphomycin tablets. As in the case of the drug "Montural", the main operating component is phosphomycin. Tablets belong to the antibiotics of a wide range of action and show a positive result for diseases of the genitourinary system. The drug is accepted inside.

One-time dose for an adult patient is 3 g. The medicine can also be appointed to children. At the same time, the one-time dose should not exceed 2 g. The duration of the course of treatment depends on the form of the disease, as well as the individual characteristics of the patient's body. Pregnant women take medicine not recommended.

Urofosfabol

The drug "Urophosfabol" is also often used for diseases of the urogenital system. A medication is produced in the form of white powder. The medicine refers to the group of antibacterial drugs-derivatives of phosphonic acid. With the help of powder prepare a solution that is introduced intravenously.

UROFOS FABOL powder can be assigned to pregnant women, as well as children from the first days of life. The dosage is calculated individually based on the patient's body mass.

"Ureacid"

The medication is produced in the form of granules that dissolve in water. The current component also performs phosphomycin. The antimicrobial means of a wide range of action allows you to quickly overcome the urinary tract infection. As well as the drug "Montoual", the analogues of domestic have age limitations. Granules "Ureacid" do not appoint children under 12 years old. The medicine is also contraindicated during pregnancy.

Medication with caution is prescribed to patients with renal failure. Such a patient is preferably carried out in a hospital.

"Fortores"

The preparation in the form of granules is often used in the treatment of cystitis in adult patients. In the acute phase of illness, the medication is accepted once. One granules is usually sufficient so that the disease retreated. Children do not prescribe medication.

Medicine "Fortise" has a number of contraindications. With caution it is worth taking the drug to people who have a tendency to allergic reactions. Sometimes it can develop hypersensitivity to individual components. Patients with a high degree of renal failure An antibacterial agent is not assigned.

Reviews of the preparation "MONURAL" and analogues

Patients noted that the medicine shows good results if you seek medical help in a timely manner. In most cases, it is enough to take only one tablet to feel relief. Without the recommendation of the specialist, still do not use the tablets "MONURAL". Instructions for use, analogues, reviews - All this is pre-learning.

Pregnant women are desirable to make a safer remedy. Good results shows the Urophosfabol medication. However, it should be used strictly for its intended purpose. According to the reviews of specialists, tablets show a positive trend in the first stages of therapy. Medication can also be used to treat small children.

On the granules of "Fortese" can also be heard a lot of positive feedback. Minus are only age limitations. The medicine is prescribed to patients over 18 years old.

Only after consultation with the doctor it is worth taking the Medicine "Montural", analogues and substitutes. The drug will give a good result only with proper use.

fB.ru.

Analogs of Montoural: Description and Principle of Action

Phosphomycin, the main active substance of the drug Monulela produced by the Swiss pharmaceutical company Zambon, has long been used in nephrology. This is a very effective means for treating almost all bacterial lesions of the urinary system organs.

But given the high price of the MONURAL drug, the analogues of this medication are prescribed to many patients. The original drug is produced in the form of a powder in Sasha, in other words, in small amounts of paper bags, from within laminated polyethylene, 2 and 3. Before use, the contents of the package are dissolved in a small amount of water. As mentioned above, the main ingredient of the monulela and its analogues is phosphomycin in the form of a troometamol connection.

To improve the organoleptic properties of the drug as auxiliary substances, the manufacturer uses a mandarine and orange flavor, sucrose, sugar. The bactericidal effect of phosphomycin is based on the oppression of the synthesis of one of the main components of the membrane of the pathogenic microorganism.

In addition, a monulela, as well as its counterparts, reduces the degree of adhesion (or "sticking") bacteria to the epithelium, lining the urinary paths. Perennial use of phosphomycin both in Russia and abroad demonstrated its effectiveness and safety in children, pregnant women, elderly patients, patients with chronic pathologies of the urinary system organs.

Analogs of the Montoual, as well as the original drug, are active in relation to major uropatogen:

  • intestinal sticks;
  • various proteus strains;
  • enterococci;
  • klebsiel;
  • singny sticks;
  • staphylococci;
  • morganla;
  • serracy.

Interesting data of clinical studies that were conducted within 5 years. Each year noted the growth of the resistance of pathogenic microflora to antibacterial drugs of cephalosporinic series (ceftriaxone, cefepim, cefuroxy) and aminoglycosides (gentamicin).

However, the sensitivity to phosphomycin remained at the same level. In addition, facilitating the clinical symptoms of diseases of the urinary system Against the background of taking a monulela and its analogues occurred much faster than after the use of cephalosporins, the temperature came to normal, and the results of the urine clinical research did not detect any deviations.

According to the instructions for use, the testimony for the purpose of phosphomycin are the following pathologies:

  • pyelonephritis;
  • cystitis;
  • urethritis;
  • bacteriuria in pregnant women flowing without any clinical manifestations;
  • prevention of bacterial infection of urinary tract in diagnostic manipulations, installation of catheter, surgical intervention;
  • postoperative microbial inflammatory processes of kidneys, bladder or urethra.

When ingestion, phosphomycin is quickly absorbed from the intestine, the maximum concentration is reached after 2.5 hours. However, this antibacterial compound does not bind to blood plasma proteins, and immediately falls into the urine. For two days, phosphomycin remains in Urin to destroy 99% of the pathogenic bacterial flora. In most cases, there is enough complete reception of a monulela.

For adults, the dosage is 3 g, for a child over 5 years old - 2, in chronic processes, it is recommended to take as many drugs after 24 hours. When carrying out the operation, doctors advise to drink a medicine 3-4 hours before surgery and a day after it in the appropriate dosage. Take the drug on an empty stomach (or not less than 2 hours after meals) after emptying the bladder.

Correction of the number and multiplicity of mongo reception and its analogues are necessary for patients with impaired renal function.

Contraindications to the use of phosphomycin is increased sensitivity to any component of the drug, children's age up to 5 years and severe renal failure.

Of the foreign analogues of Montoural, the doctor can advise such medicines:

  • Phosmisycin (Japan). The drug is released only in the form of a powder for the preparation of a solution for intravenous infusions in the dosage of 0.1, 1 and 2 g. The drug is diluted in 100-500 ml of isotonic solution of sodium chloride and introduced slowly droplet for 1.5 - 2 hours;
  • Fosphomycin ESPARMA (Germany) in the form of granules for the preparation of a suspension for intake (dosage of packaging is 3 g), applied similarly to monulela;
  • Phosphorah Romopharm (Romania), powder for the manufacture of drinking solution, 3 g;
  • EcoFomural (Switzerland), a full counterpart of a monulela, a method of cooking and dosage is identical to the original drug.

From domestic relatively cheap substitutes of Swiss phosphomycin are prescribed urophosphamfabol. More details about the application will be described below.

Many compare the monural and other antibacterial drugs for the treatment of urinary infections, for example, nolicin. This drug is produced by the Slovenian KRKA company in the form of tablets with a dosage of 400 mg. The main component is Norfloxacin. This antibiotic entered a wide clinical practice in about the 1980s. And he became a kinder of the whole group of antibacterial agents - fluoroquinolones. To date, they are numbered about 30, of which 8 are used in Russia. Nevertheless, Norfloxacin leads to patients with infections of the urinary and digestive system.

The spectrum of its action is wider than in phosphomycin, and the bactericidal effect is based on the effects directly on the microorganism DNA system. In the urological practice of Nolysin, in addition to diseases of the urinary system organs, prescribe for the treatment of sexual infections (prostatitis, cervicitis, endometritis, gororani).

However, Nolysin is contraindicated to children under 18, and during pregnancy it is appointed by "life" testimony. In other words, for these categories of patients is more preferable to monistive and its complete counterparts. In addition, the course of treatment with nolysin is at least a week. However, this antibiotic is indispensable for therapy and the prevention of chronic and recurrent infections of the urinary system.

Domestic analogues of Montoural

Domestic analogues of the drug Monulela are only two. This URO phosfabol produced by Aboband and Phosphomycin from Krasfarma. Urophosfabol is available in the form of a powder for the preparation of injections in vials with dosage of active substance, phosphomycin, 1, 2 and 4 g. Unlike a monulela, with parenteral administration, this antibiotic penetrates the lung tissue, the heart muscle well, passes through the hematorecephalic and placental barrier.

In the instructions on the use of this domestic counterpart of the monulela, the list of contraindications in addition to infections of the urinary system organs includes:

  • bacterial lesion of soft tissues, including with impaired blood flow in peripheral vessels;
  • infection of the burn surface;
  • bone and cartilage diseases provoked by pathogenic microflora;
  • infections of the lower respiratory tract (bronchitis, pneumonia);
  • bacterial inflammation of the organs of the sexual system (salpintingitis, endometritis);
  • infections of the abdominal organs (cholecystitis, cholangitis, peritonitis).

And if the monulela is contraindicated to children under 5 years old, urofosfabol is used in pediatric practice, starting from 2.5 years of age. The maximum daily dosage for adults is 6 g, divided into three receptions (usually prescribed 1 g three times a day). Child The amount of the drug is selected individually, on average this is 0.5 g 3 times a day.

Urophosphal injections cause severe pain at the injection site. This should be considered when preparing a solution and instead of water for injection or sodium chloride use local anesthetic lidocaine.

The correction of the dosage of this domestic counterpart is required with renal and heart failure. In addition, during treatment with urophophalas, breastfeeding should be suspended.

From side effects, the appearance of an allergic reaction, changes in blood pattern, dizziness, diarrhea.

The deterioration of the liver work is extremely rare, but the functioning of the organ is completely restored after the discharge of the drug. Phosphomycin Krasfarma is also available only in the form of a powder for the preparation of an injection solution in the dosage of 0.5 and 1 g. Indications and features of application are the same as for urophosphambers. The cost of packaging from 1 sachet of the drug Monulela in a dosage of 2 g is 385-400 rubles, a dosage of 3 g - 495-520 rubles.

From analogues Currently, the pharmacy can only find Phosphorus Rompharm. The price for one bag 3 g varies within 350-400 rubles. The domestic analogues of the Montoural are available only in nosocomial pharmaceutical points and the doctor's recipe for patients who are inpatient treatment is released, according to the MLC polishes.

Oksana, 45 years old.

"After at the age of 35, the bladder was treated, constantly tormented by cystitis. Previously, I had to drink antibiotics at least a week, now I saves a monural. As soon as the first symptoms appear, on the same day I drink a medicine for the night, and everything takes off as a hand. "

Victoria, 28 years old.

"Lied in a hospital with pyelonephritis. Doctors were afraid of complications, therefore, instead of an expensive imported monulela, domestic urophosfabol was advised. Of course, the injections were quite painful, but there was no trace from the disease, although there was a risk of transition of inflammation in chronic form. "

Thus, a monulela, analogues of domestic and imported, are the preparations of the first stage for the treatment of infections of the organs of the urinary system. Most often, the medicine is prescribed to pregnant and children, because such diseases are concerned with such patients often. A short-term drug treatment course does not affect its effectiveness, which is an undoubted advantage of the medicinal product.

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Monulela with cystitis: form of release of the drug, instructions for the use of antibiotic, reviews about treatment

Custitis is a common disease that occurs in the most inappropriate moment and strongly reduced quality of life. The disease brings so much inconvenience that a person wants to get rid of her as soon as possible. For her treatment, a monulela drug was created, a single reception of which is enough to eliminate the infection in most cases, which is confirmed by the recalls of patients.

Description of the drug

Cystitis is inflammation of the walls of the bladder, which is often accompanied by rapid urination to urination, a throat and burning, lumbar pains, an increase in temperature. There are a lot of reasons for the occurrence of pathology:

  • supercooling;
  • sedentary work;
  • gynecological infectious diseases passing to the organs of the urinary system;
  • non-compliance with hygiene;
  • consumption of acute food;
  • chronic inflammatory diseases;
  • diabetes;
  • menopause, etc.

Acute and chronic cystitis - video

Features of the use of a monulela for the treatment of cystitis

For the treatment of cystitis, a preparation of a monulela was created - a highly effective antibiotic of a wide range of action. Its great advantage is one-time application, so for treatment there is enough single package of the drug.

Indications for use:

  • acute bacterial cystitis and its relapses;
  • infections after operations;
  • bacterial urethritis;
  • preventive reception in front of surgical intervention.

Monulela is great for the treatment of inflammatory diseases of the lower urinary tract

The monulele prevents the subsidence of bacteria on the surface of the bladder mucosa and the formation of structural elements of microorganisms cells.

The tool inhibits the enzyme N-acetyl-transferase, which makes it impossible to divide bacteria.

The drug is effective against most gram-negative microorganisms (sinic and intestinal wand, protea, klebseyella) and gram-positive (golden and epidermal staphylococcus, enterococcus). The plus of this antibiotic is the sensitivity to it by bacteria, sustainable to many other means.

The medication is applied two hours before or after feeding. The contents of the bag are dissolved in 50 g of pure water, mixed thoroughly. The best time to use a monulela is immediately before bedtime after visiting the toilet. In special cases, prescribe repeated receptions in a day.

Release form and medication

The monulele is produced in the form of granules for the preparation of the solution. There are several dosages: 2 and 3 grams.

The drug is not made in the form of tablets.

Its active substance is phosphomycin thrometamol. As auxiliary substances are used:

  • flavoring of citrus flavor;
  • saccharin;
  • sucrose.

The monulele is quickly absorbed in the stomach, it is not metabolized in the body and in large quantities accumulates in the bladder. The concentration sufficient to destroy bacteria is kept within a few days, due to which only one packaging is enough to destroy the pathogens of the disease.

Possible side effects and contraindications

The use of a monulela is allowed, starting from five years. Contraindications are individual intolerance to the components of the means and renal failure. With caution, it should be applied to people suffering from diabetes, as in one package it contains about 2.2 g of sucrose. Do not be taken simultaneously with metoclopramid, since the concentration of the monulela will decrease and it will be not enough for treatment.

The main side effects are:

  • diarrhea;
  • heartburn;
  • nausea;
  • skin rash;
  • allergy;
  • thrush.

Application of the drug during pregnancy and breastfeeding

Despite the fact that the monulela is not forbidden to use pregnant women, it is an antibiotic, which can only be recommended by a doctor and in rare cases when other possible treatments do not result. At the moment, the teratogenic effect of the drug on the fetus was not registered, although not a full experiment was carried out.

In the first trimester, antibiotics are very dangerous, with caution they can be used from 4 months of pregnancy.

Breastfeeding is better to stop at the time of treatment with the drug.

How to treat cystitis during pregnancy - video

Analogs and Monulela Replacements - Table

Medicines for the treatment of cystitis - Photo Gallery

Phosphorus - full analogue of the monulela Nolysin - a strong antibiotic of a wide range of Nitroxoline - a popular cheap Uroantisaptic Palina - widely used in urology drug