Ventoline children instructions for use. Ventolin: Instructions for applying aerosols, nebul, tablets and syrup

Date: 04.07.2020

The site provides reference information solely to familiarize yourself. Diagnosis and treatment of diseases must be under the supervision of a specialist. All drugs have contraindications. Consultation of a specialist is obligatory!

Ventoline preparation

Ventolin It is an anti-asthma drug, which is used to treat various diseases of the bronchi and lungs, accompanied by a spasm of a smooth muscles of bronchi. This drug, which is transparent liquid (sometimes can be light yellow), applies only for inhalation administration.

It includes:

the active ingredient is salbutamol, which suppresses the reactivity of the bronchi and contributes to the elimination or prevention of the appearance of bronchospasm;
auxiliary substances contribute to more convenient administration of salbutamola and its uniform distribution when administered.

When the ventoline is introduced into the respiratory tract, Salbutamol affects the smooth muscles of the bronchi, ensuring their full relaxation, reducing the resistance of the respiratory tract and an increase in the amount of inhaled air. In addition, the active component of Ventoline is able to stimulate the secretion of the bronchial glands and intensify the work of the fiscal epithelium of the bronchi, which ensures the removal of mucus during cough. Salbutamol in therapeutic doses may cause palpitations and decrease in blood pressure.

The decomposition of salbutamola is derived from the body with urine and, partly with the feet.

Forms of release

Ventolin Nebules - in the form of a solution for inhalation with a nebulizer, in opaque nebulum 2.5 mg / 2.5 ml of 10, 20 and 40 pcs. in cardboard packaging.
Ventolin Evohaler - In the form of an aerosol cylinder with a spray mouthpiece containing 100 μg / 200 doses, 1 cylinder in cardboard packaging.

Instructions for the use of Ventoline

Indications for use

1. Bronchial asthma :

to relieve attacks;
to prevent attacks;
for the treatment of asthma during exacerbation.

2. Chronical bronchitis .
3. Acute obstructive bronchitis.
4. Chronic obstructive pulmonary disease with reversible obstruction.

Contraindications

Increased sensitivity to any of the components of the drug;
age up to 2 years;
the threat of miscarriage or premature birth.

Ventoline prescribed with caution at:

tahiaritimia;
aortal stenosis;
arterial hypertension;
diabetes mellitus in the decompensation stage;
renal or liver failure;

In rare cases, Ventoline can also be used to treat pregnant and nursing mothers, but only in cases where the Woman's expected effect from him exceeds the risk of developing pathologies from the fetus or child. This precaution is explained by the fact that during the tests there were cases of identifying such pathologies of the fetus as "wolf fall" and congenital deformations of the limbs.

The reliable causal relationship between the intake of Ventoline and the deformities of the fetus was not established, since other drugs were taken. There are no reliable data and about the possible negative impact on a newborn child who is probably present in sall milk salbutamola. That is why Ventoline is appointed pregnant and lactating women only in exceptional cases.

Side effects

Frequent:

shake of skeletal muscles;
tachycardia.

Infrequent:

heartbeat;
muscle spasm;
irritation of the mucous membrane of the mouth and pharynx.

Rare:

expansion of peripheral blood vessels;
hypokalemia.

Very rare:

allergic reactions (swelling, urticaria, collapse or decreased blood pressure, paradoxical bronchospasm);
hyperactivity;
super trigger tachycardia;
lactoacidosis;
addictive with long-term use.

Ventoline treatment

How to take Ventoline?
Solution for inhalation

Special instruments are used to use ventoline nebuisers - nebulizers. The inhalation solution is prepared from the prescribed amount of the ventoline solution, which is complemented by a sterile saline to a volume of 2-2.5 ml. The resulting solution is inhaled by patients through a nebulizer until the emergence of an aerosol is ceased. As a rule, the duration of inhalation is about 10 minutes.

In some cases, to achieve a faster effect, an undiluted Ventoline solution is used, which in the prescribed dosage physician is placed in a nebulizer. In such cases, inhalation lasts about 3-5 minutes.

During the procedure, the room should be well ventilated; The patient must be under the direct supervision of the doctor.

Spray can
To use the Ventoline Evohal aerosol during the first application or if the drug has not been used for a week or more, it is necessary to remove the safety cap from the cylinder, slightly squeezing its edges from the sides. The balloon needs to shake and press the inhaler valve in order to make sure that the aerosol mechanism is good.

After installing the mouthpiece, the inhaler must be sharpened again and placed the balloon in hand as follows: the bottom of the cylinder must be directed upwards, the thumb must be placed on the base under the mouthpiece, and the index to hold the inhaler in the bottom area.

The patient should make a deep and slow exhalation, clasp the lips the end of the mouthpiece (without capturing his teeth). Next, it is necessary to deeply inhale through the mouth and simultaneously press the index finger to the bottom of the inhaler. After the introduction of one dose of Ventoline, it is necessary to hold the breath for a few seconds and slowly exhale. The introduction of the next dose can be performed in the same way after 30 seconds. After that, the mouthpiece can be closed with a cap.

In the inhalation administration of Ventoline, the patient should not make movement hurry. In the first days of aerosol, you can practice in front of the mirror: if traces of the emerging aerosol in the area of \u200b\u200bthe mouth or the upper part of the inhaler are noticeable, then the administration of the drug dose must be started again.

To clean the mouthpiece, which should be carried out 1 time in 6-7 days, you can use flowable warm water.
1. Before washing, you need to remove a plastic case cylinder and remove the mouthpiece cover.
2. The housing and mouthpiece wash under the jet of warm water, preventing overheating.
3. Details to dry, insert a cylinder into the plastic case and put the mouthpiece on it.
4. Caller can not be immersed in water.

Ventolina dosage
Solution for inhalation
Ventoline Nebules can be used in a divorced form or in undiluted. The dosage and method of administration is determined by the doctor, depending on the health status of the patient and its age.

Adults and children over 12 years old:

in the diluted form - 0.5-1.0 ml (2.5-5.0 mg of ventoline) mixed with sterile saline, bringing volume to 2.0-2.5 ml. The solution is placed in a nebulizer and inhalation is carried out until evaporation of evaporation (about 10 minutes).
nearby - 2.0 ml (10 mg of ventoline) is placed in a nebulizer and conduct inhalation (about 3-5 minutes).

Children 18 months-12 years:

in a divided form - 0.5 ml (2.5 mg of ventoline), it is brought to a sterile physiological solution to a volume of 2.0-2.5 ml, the resulting solution is placed in a nebulizer and perform inhalation.
in severe cases, the dose increases to 1.0 ml (5.0 mg of ventoline), the drug is bred by a sterile physiological solution to a volume of 100 ml and inhalation using an aerosol or nebulizer at a speed of 1-2 mg / hour.

The number of inhalation is determined by the doctor. If necessary, re-inhalation can be carried out after 20 minutes. It is not recommended to perform the introduction of Ventoline more than 4 times a day.

Spray can
Adults:

with an acute attack of bronchospasm - 100-200 μg (1-2 injection);
prevention of acute attack of bronchospasm during physical voltage or exposure to allergen - 200 μg (2 injection) for 10 -15 minutes to the effect of provocating a factor;
supporting therapy, appointed for a long period of time - 200 μg (2 injection) up to 4 times a day.

Children from 18 months to 2 years:

with an acute attack of bronchospasm - 100 μg (1 injection);
prevention of the attack of bronchospasm - 100 μg (1 injection) 10-15 minutes before the effect of provoking the attack of the factor;
supporting therapy appointed for a long period of time is 100 μg (1 injection) up to 4 times per day.

Increase the efficiency of using ventoline can use additional devices - spacers (voluumatic, Bebikhaler, etc.). Spacers are recommended for inhalations and those patients who are difficult to coordinate their actions when using an aerosol.

Ventoline Children

Ventoline can be applied to the treatment and prevention of bronchospasm in children, starting from 2-year-olds. As a rule, it can be prescribed even at 18 months. At earlier age, Ventoline is applied in rare cases, since the possible negative effect of the drug on the child's body under 18 months is not yet sufficiently studied.

Most often, Ventoline in pediatric practice is appointed by a short period of time. At the same time, the age of the child, the severity of bronchospasm, the presence of concomitant diseases, receiving other drugs and the risk of possible side effects.

To increase the efficiency of the drug or at the impossibility of using the Ventoline aerosol, the introduction of salbutamol can be recommended using a nebulizer or the use of aerosol through the spacer (Bebikhaler, Volume). Dosage of salbutamola, frequency and nature of administration, duration of application - all these parameters are installed by a doctor individually for each child.

Analogs of Ventolin

Analogs (synonyms) Ventolin, containing in its composition the same active ingredient - salbutamol:

Aloprol;
Astalin;
Volmax;
Salamol (stary sky, light breathing and eco);
Salmo;
Salben;
Salbouvent;
SalmBututol (MHF, TEV, base, native);
Salgim;
Saltos;
Slerine Salamole;
Cyclopax cybutol.

Aspen Bad Oldezlo GmbH Glakso Lelkom GmbH & Ko Glaxo Lelkom GmbH and Glaxo Lelkom Production Glasosmitklein GmbH and Co. Kg / Humann Pharma GmbH Glasosmitklein Pharmal S.A.

Country of origin

Germany Spain Poland France

Group of goods

Respiratory system

Broncholic drug - beta2 adrenomimetics

Forms of release

2.5 ml - polyethylene ampoules, soldered in the form of a strip (10) - Laminated aluminum foil packages (2) - Cardboard packs. 200 Doses - aluminum inhalers (1) with a plastic dosing device with a protective cap - packs cardboard.

Description of the dosage form

Aerosol for inhalations metered in the form of a suspension of white or almost white. The solution for inhalations in nebulah in the form of a transparent liquid from colorless to light yellow.

pharmachologic effect

Celexive beta2-adrenoreceptor agonist. In therapeutic doses, it acts on the beta2-adrenoreceptors of the smooth muscles of the bronchi, having a minor influence or at all without affecting beta1-adrenoreceptors of myocardium. It has a pronounced bright effect, warning or binding bronchospasm, reduces resistance in the respiratory tract. Increases clothes Increases mukiciliary clearance (with chronic bronchitis up to 36%), stimulates the secretion of mucus, activates the functions of the fiscal epithelium. In the recommended therapeutic doses, there is no negative impact on the cardiovascular system, it does not cause an increase in blood pressure. To a lesser extent, compared with the drugs of this group, has a positive chrono - and inotropic effect. Causes the expansion of the coronary arteries. It has a number of metabolic effects: reduces plasma potassium concentration, affects glycogenolysis and insulin selection, hyperglycemic (especially in patients with bronchial asthma) and a lipolytic effect increases the risk of acidosis. After applying inhalation forms, the action is developing quickly, the beginning of the effect - after 5 minutes, a maximum - after 30-90 minutes (75% of the maximum effect is achieved for 5 minutes), duration - 4-6 hours.

Pharmacokinetics

Suction and metabolism after the inhalation administration of 10-20% dose of salbutamola reaches the lower respiratory tract. The rest of the dose remains in the inhaler or postponed in the rotoglotka and then swallows. The fraction deployed in the respiratory tract is absorbed into pulmonary fabrics and blood, but not metabolized in the lungs. The sworded part of the inhalation dose is absorbed from the gastrointestinal dose and is subjected to intense metabolism at the "first passage" through the liver, turning into inactive 4 "-O-sulfate (phenolic sulfate). Distribution of the Salbutamola binding with plasma proteins is 10%. EXTENSION C / IN / 2 Salbutamola is 4-6 hours. The unchanged salbutamol and the conjugate are excreted mainly with urine. With the feces, only a small part of the administered dose of Salbutamola is derived. Most of the dose of salbutamola, introduced into the body in / in, inside or by inhalation is derived within 72 hours.

Special conditions

Patients should be instructed to use the magazine inhaler Ventoline. Bronchodulators should not be the only or basic component of the therapy of the bronchial asthma of an unstable or severe flow. If the action of the usual dose of Ventoline becomes less efficient or less long (the effect of the drug should be maintained at least 3 hours), the patient should consult a doctor. Improving the need for the use of inhalation agonists of beta2-adrenoreceptors with a short duration of action to control the symptoms of bronchial asthma indicates the exacerbation of the disease. In such cases, the patient's treatment plan should be revised. A sudden and progressive deterioration of bronchial asthma may pose a threat to the patient's life, so in such situations it is necessary to urgently address the issue of appointing or increasing the dose of glucocorticosteroids. In such patients, it is recommended to carry out daily monitoring of the peak speed of the exhalation. Very high doses of salbutamola can lead to the development of adverse reactions, so only a doctor can solve the issue of increasing the dose or the frequency of use of the drug. Patients using ventoline nebula at home must be prevented that if the action of a conventional dose becomes less efficient or less long, it is impossible to independently increase the dose or frequency of administration of the drug, and you need to immediately consult a doctor. Ventoline Nebules should be used with caution in patients who have already taken high doses of other sympathomimetics. Salbutamol must be used with caution in patients with thyrotoxicosis. Therapy with agonists of beta2-adrenoreceptors, especially when administered by parenterally or with a nebulizer, can lead to hypokalemia. It is recommended to show special care in the treatment of heavy bouts of bronchial asthma, since in these cases hypocalemia may increase as a result of the simultaneous use of xanthine derivatives, glucocorticosteroids, diuretics, as well as due to hypoxia. In such situations it is necessary to control the level of potassium in serum.

Structure

salbutamol Sulfat120.5 μg, which corresponds to the content of salbutamola100 μg. Auxiliary substances: propellant GR106642X (1,1,1,2-tetrafluoroethane, HFA 134a, Norflouran); Does not contain chlorofluorocarbons of salbutamol sulfate3 mg, equivalent to salbutamol 2.5 mg. Auxiliary substances: sodium chloride, sulfuric acid diluted, purified water. Salbutamola sulfate3 mg, equivalent to salbutamolu2.5 mg Average substances: sodium chloride, sulfuric acid Divorced, purified water.

Ventoline Indications for use

You should instruct the patient about the correct use of inhaler Ventoline. Bronchodulators should not be the only or basic component of the therapy of the bronchial asthma of an unstable or severe flow. If the effect of the usual dose of ventoline becomes less efficient or less long (the effect of the drug is preserved at least 3 hours), the patient should consult a doctor. Improving the need for the use of inhalation agonists of beta2-adrenoreceptors with a short duration of action to control the symptoms of bronchial asthma indicates the exacerbation of the disease. In such cases, the treatment plan should be revised. A sudden and progressive deterioration in the flow of bronchial asthma may pose a threat to the patient's life, so in such situations it is necessary to urgently address the issue of appointing or increasing the dose of GKS. In such patients, it is recommended to carry out daily monitoring of the peak speed of the exhalation. With caution to apply the drug in the patient

Ventolin Contraindication

- maintaining premature births; - threatening abortion; - children's age up to 2 years; - Increased sensitivity to the components of the drug. With caution, the drug should be used if the patients have a history of tachyrhythmia, myocarditis, heart defects, aortic stenosis, CHS, heavy chronic heart failure, arterial hypertension, thyrotoxicosis, pheochromocytoma, decompensated diabetes, glaucoma, epileptic seizures, renal or liver failure; Simultaneously with non-selective beta-adrenoblockers, during pregnancy, during the period of lactation

Ventoline Dosage

100mkg / dose 1mg / ml

Ventolin Side Actions

Allergic reactions: very rarely - hypersensitivity reactions, including urticaria, angioedema edema, bronchospasm, arterial hypotension and collapse. From the CNS: often - tremor, headache; Very rarely - hyperactivity. From the side of the cardiovascular system: often - tachycardia; Sometimes - severe heartbeat (pulsation, palitation); rarely - expansion of peripheral vessels; Very rarely arrhythmias, including flickering arrhythmia, supraventricular tachycardia and extrasystolia. From the respiratory system: very rarely - paradoxical bronchospasm. From the digestive system: sometimes irritation of the mucous membrane of the oral cavity and pharynx. On the side of the musculoskeletal system: sometimes muscle cramps. From the metabolism: rarely - hypokalemia. Therapy with agonists? 2-adrenoreceptors can lead to severe hypokalemia. Very rarely - lactacidosis. Very rare cases of lactacidosis were registered in patients who received salbutamol in / in and Ventoline Nebula to treat Bronchial asthma exacerbations

Medicinal interaction

It is not recommended to simultaneously apply salbutamol and non-selective blockers? -Adrenoreceptors, such as propranolol. Salbutamol is not contraindicated to patients who receive Mao inhibitors. In patients with thyrotoxicosis, Ventoline enhances the effect of CNS stimulants, tachycardia. Theophylline and other xanthines with simultaneous use with salbutamol increase the likelihood of developing tachyritium. With the simultaneous use of the drug with a means for inhalation anesthesia, the risk of heavy ventricular arrhythmias increases with the levodopa. Simultaneous appointment with anticholinergic agents (including inhalation) can contribute to an increase in intraocular pressure. Diuretics and GCS enhance the hypocalemic effect of salbutamola.

Overdose

often - hypokalemia, decreased blood pressure, tachycardia, muscle tremor, nausea, vomiting; less often - excitation, hyperglycemia, respiratory alkalosis, hypoxemia, headache; Rarely - hallucinations, cramps, tachyarhythmias, ventricular fluttering, expansion of peripheral vessels.

Storage conditions

bear from children
storing

Information provided

Aerosol for inhalations dosage - 1 dose:

active substance: Salbutamola Sulfate - 120.5 μg (equivalent to 100 μg salbutamola);
auxiliary substances: Tetrafluoroethane - 1 dose.

In the balloon aerosol aluminum (complete with a metering device); In a pack of cardboard 1 cylinder.

Description of the dosage form

The inhalation aerosol was dosed: an aluminum inhaler equipped with a plastic dosing device with a protective cap containing a suspension of white or almost white.

pharmachologic effect

Bronching, beta adrenomimetic.

Pharmacokinetics

After the inhalation administration of 10-20%, the dose of salbutamol reaches the lower respiratory tract. The rest of the dose remains in the inhaler or postponed in the rotoglotka and then swallows. The fraction deployed in the respiratory tract is absorbed into pulmonary fabrics and blood, but not metabolized in the lungs.

The degree of binding salbutamola with plasma proteins is about 10%.

The salbutamol fell into the blood is subjected to metabolism in the liver and excreted, mainly with urine, unchanged or in the form of phenolic sulfate.

The swallowed part of the inhalation dose is absorbed from the gastrointestinal tract and is subjected to active metabolism at the first passage through the liver, turning into phenolic sulfate. The unchanged salbutamol and the conjugate are excreted mainly with urine.

The salbutamol introduced in / in Salbutamol has T1 / 2 4-6 h. It is separated in part by the kidneys and partially as a result of metabolism to the inactive 4 "-o-sulfate (phenolic sulfate), which is also excreted mainly with the urine. With the feces, only a small part of the introduced dose is excreted. Salbutamola. Most of the dose of salbutamola, introduced into the body in / in, oral or inhalation, is excreted within 72 hours.

Pharmacodynamics

Salbutamol is a selective β2-adrenoreceptor agonist. In therapeutic doses, it acts on the β2-adrenoreceptors of the smooth muscles of the bronchi, having a slight effect or at all without affecting the β1-adrenoreceptors of myocardium. It has a pronounced bright effect, warning or binding bronchial spasms, reduces resistance in the respiratory tract. Increases the life capacity of the lungs. Increases mukiciliary clearance (with chronic bronchitis up to 36%), stimulates the secretion of mucus, activates the functions of the fiscal epithelium.

In the recommended therapeutic doses, there is no negative impact on the SCC, does not cause an increase in blood pressure. To a lesser extent, compared with the LS of this group, has a positive chrono- and inotropic effect. Causes the expansion of the coronary arteries.

It has a number of metabolic effects: reduces plasma potassium concentration, affects glycogenolysis and insulin selection, hyperglycemic (especially in patients with bronchial asthma) and a lipolytic effect increases the risk of acidosis.

After applying inhalation forms, the action is developing quickly, the beginning of the effect - after 5 minutes, a maximum - after 30-90 minutes (75% of the maximum effect is achieved for 5 minutes), duration - 4-6 hours.

Instruction

Checking the inhaler: Before the first use of the inhaler or in the event that the inhaler did not use a week or longer, you should remove the cap from the mouthpiece, slightly squeezing the cap from the sides, shake the inhaler well and click on the aerosol valve to release 1 inhalation dose into the air to make sure In the health of the inhaler.

Using inhaler

Remove the cap from the mouthpiece, slightly squeezing the cap from the sides.
Inspect the mouthpiece from the inside and outside to make sure it is clean.
Shake inhaler well.
To keep the inhaler between the index and thumbs in a vertical position, while the thumb should be located on the mouthpiece.
Make a slow deep exhalation, clasping mouthpiece with lips, without squeezing his teeth.
Making a deep breath through the mouth, simultaneously press the upper part of the inhaler to release the 1 inhalation dose of salbutamola.
To delay your breath for a few seconds, remove the mouthpiece from the mouth, then slowly exhale.
To obtain a second dose, holding a inhaler in a vertical position, wait about 30 seconds and then repeat items 3-7.
Tightly close the mouthpiece with a protective cap.

Attention! Performing paragraphs 5, 6 and 7 - you can not hurry. It should be inhaled as slowly as possible, immediately before pressing the inhaler valve. In the first few times it is recommended to practice in front of the mirror. If the "fog" is visible, leaving the top of the inhaler or from the corners of the mouth, then it should be started again from paragraph 3.

If the doctor gave other instructions for using the inhaler, it should be strictly observed them. It is necessary to contact your doctor if difficulties arise with the use of the inhaler.

Cleaning inhaler: Inhaler must be cleaned at least 1 time per week.

Extract a metal plastic casing bracket and remove the mouthpiece cover.
Rinse the plastic case and the mouthpiece cover under the jet of warm water.
Dry the plastic housing and the mouthpiece cover is completely both outside and inside. Do not overheat.
Place a metal canopy in a plastic case and put on the mouthpiece cover.

Do not immerse the metal can be immersed in water.

Indications for the use of Ventoline

Bronchial asthma:

the relief of the attacks of bronchial asthma, incl. With the exacerbation of the bronchial asthma of severe flow;
preventing the attacks of bronchospasm associated with the effects of allergen or caused by exercise;
application as one of the components with long-term supporting bronchial asthma therapy;

COPD accompanied by reversible respiratory tract.

Chronical bronchitis.

Contraindications for the use of Ventoline

increased sensitivity to any component of the drug;
maintaining premature births;
threatening abortion;
children's age up to 2 years.

With caution: Tahiarhythmia, myocarditis, heart patterns, aortic stenosis, CHS, heavy chronic heart failure, arterial hypertension, thyrotoxicosis, feuhromocytoma, decompensated diabetes mellitus, glaucoma, epiphes, renal or hepatic insufficiency, simultaneous reception, periodical β-adrener lactation.

Ventoline application during pregnancy and children

Pregnant women drug is prescribed only when the expected benefit for the patient exceeds the potential risk to the fetus.

In the course of the post-registration observation, rare cases of various malformations in children were revealed, including the formation of wolf pastries and the defects of the development of the limbs, against the background of taking mothers during pregnancy Salbutamola. In some of these cases, mothers took several concomitant drugs during pregnancy. The causal relationship with the reception of the drug is not established.

Salbutamol probably penetrates into breast milk, so it is not recommended to be prescribed to nursing women with the exception of those cases where the expected benefit for the patient itself outweighs the potential risk for the child. There is no data on whether the Salbutamol has a harmful effect on the newborn present in breast milk.

Ventolin Side Actions

Unwanted reactions are listed depending on the anatomy-physiological classification and frequency of occurrence, which is defined as follows: Very often (≥1 / 10), often (≥1 / 100 and

From the immune system: very rarely - hypersensitivity reactions, including angioedema, urticule, bronchospasm, hypotension and collapse.

From the metabolism: rarely - hypokalemia (therapy β2-agonists can lead to meaningful hypokalemia); Very rarely - lactoacidosis. Very rare cases of lactoacidosis were recorded in patients who received Salbutamol V / B and Ventoline Nebules to treat the exacerbations of bronchial asthma.

From the nervous system: often - tremor, headache; Very rarely - hyperactivity.

From the side of the SCC: often - tachycardia; Sometimes - severe heartbeat (pulsation, palitation); rarely - expansion of peripheral vessels; Very rarely - arrhythmia, including flickering arrhythmia, suctivativericular tachycardia and extrasystolia.

From the side of the respiratory system, the chest and mediastinum organs: very rarely - paradoxical bronchospasm.

From the head of the gastrointestinal: sometimes - irritation of the mucous membrane of the mouth and pharynx.

On the side of the musculoskeletal system: sometimes muscle cramps.

Salbutamol is not contraindicated to patients who receive Mao inhibitors.

In patients with thyrotoxicosis, the effect of CNS stimulants and tachycardia increases.

Theophylline and other xanthines with simultaneous use increase the likelihood of development of tachyarhythmias; Means for inhalation anesthesia, levodopa - heavy ventricular arrhythmia.

Simultaneous purpose with anticholinergic agents (including inhalation) can contribute to an increase in intraocular pressure.

Diuretics and GCS enhance the hypocalemic effect of salbutamola.

Dosage Ventoline

Inhalation Only a doctor can resolve the issue of increasing the dose or frequency of the drug. It is not recommended to apply inhaler Ventolin® more often than 4 times a day. The need for the use of maximum doses of Ventoline® or in a sudden increase in the dose indicates a deterioration in the course of the disease.

Adults (including elderly patients)

Preventing the attacks of bronchospasm related to the effects of allergen or by physical activity: the recommended dose is 200 μg (2 inhalations) for 10-15 minutes before the impact of the provoking factor.

Preventing the attacks of bronchospasm associated with the effects of allergen or by physical activity: the recommended dose is 100-200 μg (1-2 inhalation) for 10-15 minutes before the impact of the provocating factor.

Overdose

Symptoms: more frequent - hypokalemia, decreased blood pressure, tachycardia, muscle tremor, nausea, vomiting; Less frequent - excitation, hyperglycemia, respiratory alkalosis, hypoxemia, headache; Rare - hallucinations, cramps, tachyarhythmias, ventricular fluttering, expansion of peripheral vessels.

Treatment: Cardooselective β-adrenoblays are the best antidote. However, β-adrenoreceptor blockers should be used with caution in patients with bunch of bronchospasm in history. The use of large doses of salbutamola can cause hypocalemia, so when suspected an overdose, the level of potassium in serum should be monitored.

Precautions

Instructing patients on the proper use of the Ventoline® inhaler.

Bronchodulators should not be the only or basic component of the therapy of the bronchial asthma of an unstable or severe flow.

If the action of the usual dose of Ventolin® becomes less efficient or less long (the effect of the drug should be maintained at least 3 hours), the patient should consult a doctor.

Improving the need for the use of inhalation agonists of β2-adrenoreceptors with a short duration of action to control the symptoms of bronchial asthma indicates the exacerbation of the disease. In such cases, the patient's treatment plan should be revised. A sudden and progressive deterioration in bronchial asthma may pose a threat to the patient's life, so in such situations it is necessary to urgently address the issue of appointing or increasing the GKS dose. In such patients, it is recommended to carry out daily monitoring of the peak speed of the exhalation.

Salbutamol must be used with caution in patients with thyrotoxicosis.

Therapy by agonists of β2-adrenoreceptors, especially when administered by parenterally or with a nebulizer, can lead to hypokalemia. It is recommended that it is recommended for particular caution in the treatment of severe bouts of bronchial asthma, since in these cases hypocalemia may increase as a result of the simultaneous use of xanthine derivatives, GKS, diuretics, as well as due to hypoxia. In such situations it is necessary to control the level of potassium in serum.

Impact on the ability to drive a car and / or other mechanisms. There is no data.

Ventoline has an impact on the adrenoreceptors of the smooth muscles of the bronchi, causing a pronounced bright effect and practically without affecting the myocardial adrenoreceptors. Pharmacological action continues within 4 hours after reception.

The main active substance is Salbutamol. In the recommended therapeutic doses, there is no negative impact on the SCC, does not cause an increase in blood pressure. A to a lesser extent is a positive chrono and inotropic effect. Causes the expansion of the coronary arteries.

Salbutamol suppresses the early and late reactivity of the bronchi, reduces resistance in the respiratory tract, and also prevents or binds spasm in bronchi. In addition, the drug contributes to an increase in the life capacity of lungs and mucociliary clearance, and also activates the functions of the fiscal epithelium and stimulates the secretion of the mucus.

The drug is produced in the following forms:

Tablets - 20, 50 and 100 pcs. In 1 pack, 1 tab. contain 2 and 4 mg of salbutamol.
150 ml syrup in a bottle - 2 mg in 1 ml.
Two-layer tablets 0.008 g to 20 or 50 pcs. packaged.
Cyrose for internal reception - 2 mg in 2 ml, in a 50 ml bottle.

Ventoline for inhalations:

Nebules (dosage aerosol in plastic ampoules) - 200 doses in 1 bottle. 2.5 ml in nebule.
Dosage aerosol without freon (chlorofluorocarbons, which destroy the ozone layer) - 200 doses in 1 vial. 100mkg salbutamola in 1 dose.

Indications for use

What helps Ventoline? Prescribed the drug in the following cases:

the relief of the attacks of bronchial asthma, incl. With the exacerbation of the bronchial asthma of severe flow;
preventing the attacks of bronchospasm associated with the effects of allergen or caused by exercise;
application as one of the components with long-term supporting bronchial asthma therapy.
chronic obstructive pulmonary disease (COPD), accompanied by a reversible respiratory tract, chronic bronchitis.

Instructions for the use of ventoline, dosage

Nebules

not intended for injections. Ventoline is administered in inhalation using a nebulizer with a mask, an endotracheal or T-shaped tube. In hypoplation, hypoxia can occur, then inhaled air can be enriched with oxygen.

Nebules are applied without dilution, but if necessary, long-term inhalation (more than ten minutes) can be dissolved with a sterile 0.9% sodium chloride solution.

The drug should be used in well-ventilated premises, as part of the drug when inhalation enters the environment. This is especially important in a hospital, where nebulizers can use several patients simultaneously.

The initial dosage of Ventoline during inhalation administration with a nebulizer is 2.5 milligrams, but if necessary, up to five milligrams can be increased. Inhalations can be held up to four times a day. Under the hospital, with a pronounced respiratory tract, dose for adult patients can be increased to 40 mg / day.

The clinical efficacy of applications in children under eighteen months by introducing through the nebulizer was not studied.

Spray can

The inhalation aerosol is designed to use 200 times. Adults and children from 2 years can enjoy.

For long-term supporting therapy, adults are usually prescribed 200 μg to 4 times a day. To prevent bronchospasm in childhood, 100-200 μg is used (1-2 inhalation).

Before using an aerosol, a cap is removed from the mouthpiece with a mouthpiece, they are convinced that the mouthpiece is clean, the can of the balloon is vigorously. After that, the mouthpiece is introduced into the mouth, clasp lips. Now you should make a deep and slow exhalation through the nose.

Then you need to breathe as closely through the mouth as possible, at the same time pressed on the upper part of the inhaler and released 1 dose of the drug. Inspoping, for a few seconds you need to hold your breath, remove the mouthpiece from the mouth and slowly exhale. If the second Aerosol is needed, then after a 30-second break, the procedure can be repeated.

Syrup

It is prescribed to patients in adulthood 2 ml 3-4 times a day. If necessary, the dosage can be increased to 4 ml.

Standard dosage

Resting the attack of bronchial asthma - no more than 4 times a day:

For adults, the dose is 100 - 200 μg.
Children - 100 μg (in severe cases - 200 μg) Salbutamola.

Prevention of bronchospasm:

Adults are recommended inhalation introduction of 200 μg salbutamola 15 minutes to expected load or contact with an allergen.
Children recommended a dosage of 100 μg, but if necessary, it can be increased to 200 μg.

Supporting therapy:

Adults and children are 100 μg to 4 times a day.

Side effects

The appointment of Ventoline may be accompanied by the following side effects:

easy tremor hands
headache,
excitation and hyperactivity in children
expansion of vessels and an increase in heart rate,
heart rate violation
paradoxical bronchospasm,
allergic reactions (arterial hypotension, angioedema edema, bronchospasm).

Contraindications

Contraindicated to prescribe Ventoline in the following cases:

increased sensitivity to any component of the drug;
maintaining premature births;
threatening abortion;
children's age up to 2 years.

Overdose

Symptoms of overdose:

reduced blood pressure
tachycardia,
muscle tremor,
nausea and vomiting.

The use of large doses of salbutamola can cause metabolic changes, including hypokalemia, it is necessary to control the concentration of potassium in serum.

Analogs of Ventoline, price in pharmacies

If necessary, replaced Ventoline on an analogue by ATX code - these are drugs:

Astalin,
Salamole
Salgim,
Salmo.

Choosing analogues It is important to understand that the instructions for use of Ventoline, the price and reviews for drugs of similar action do not apply. It is important to obtain a doctor's advice and not to produce an independent replacement of the drug.

Price in Pharmacies of Moscow: Ventoline 100mkg / dose 200 Dose aerosol for inhalations - 139 - 154 rubles, nebules solution 1 mg / ml 20 pcs. - 268 - 282 rubles.

Store in an inaccessible place at temperatures not higher than +30 ° C. Do not freeze and not expose direct sunlight. Shelf life - 2 years. The pharmacies are released on the recipe.

Latin name:Ventolin.
ATH code: R03A C02.
Active substance:
Manufacturer: ASPEN BAD Oldesloe GmbH (Germany),
"Glaxo Smith Kline" (United Kingdom),
"Farmaclair" (France)
Vacation from Pharmacy: On prescription

The drug Ventoline is not hormonal. MNT of its current component - Salbutamol. It has a bright effect, stopping and preventing the reductions of the bronchi, will investigate the obstruction of the respiratory system.

Indications for use

Symptoms, diseases and complications of which is appreciated by Ventolin:

Bronchospasm
Allergy
Bronchitis in acute form
Emphysema
Bronchial asthma.

The composition of the drug

The drug is produced in different forms, which determines the concentration of the active component in the dosage recommended for receiving.

Nebules for inhalations (2.5ml). The main component is salbutamol in the amount of 2.5 mg. Additional components of the solution: water (purified), sulfuric acid (non-concentrated), sodium chloride
Spray. The main drug substance is salbutamola sulfate (micronized) 120,5 MGK / 1 dose, in the inhalation bottle by 100 doses - 28.92 mg of the drug. Additional component: Propellente - up to 75mg / 1 dose
Tableted form. Tablets containing 2 mg, 4 mg, 8 mg of salbutamola are produced. Additional Components: Magnesium Stearate, Aerosil 200, Cellulose (Microcrystalline), Talc (Purified)
Syrup. The vial of 150ml contains salbutamol in the amount of 2 mg in 5 ml of syrup. Ventoline syrup (50 ml) is more concentrated: in 1 ml 1 mg salbutamola. Additional Components: Lemon Acid, Food Supplement E110 (Dye), Strawberry Corrigent, Hydroxypropylmethylcellulose (Food Supplement / Stabilizer), Sakharin, Sodium Benzoate, Sodium Lemon-Chondulous Three-Restored Two-Water, Water (Purified).

Medical properties

The most positive therapeutic signs of impact differ in ventoline for inhalations. If you get into the body, it immediately provides a wide range of actions, improving well-being in the first minutes after the inhalation procedure. The positive effect is maintained at least 4 hours.

Impact of Ventolin on the body:

Saving release from fat cells of histamine, leukotriene, prostaglandin
Braking reactivity bronchi
Increase lung life capacity
Awakening Fimer Epithelium Functions
Production of lipolytic and hyperglycemic effect
Manifestation of satisfactory inotropic and chronotropic action
Normalization of respiration and overcoming resistance
Reducing bronchial spasms caused by allergen
Raising mukiciliary clearance
Reducing the concentration of potassium content in the circulatory system
Influence on the production of insulin and glycogenolysis
Expansion of coronary arteries.

Ventoline's medicine is inherent in the unique properties of self-harvesting from the body, which greatly facilitates the work of the liver. When inhalation in the body, only 20-30% of the dose used falls, the rest is settled on the inner walls of the nose and mouth. Penetrating into the internal organs of the respiratory system, the drug enters the bloodstream freely, in the lungs it does not settle and does not convert.

Through the blood components fall into the liver, where they are processed, derived with urine in a constant chemical compound. Approximately 70-80% of the dose of ventoline used on the portable apparatus and the nasophal, falls into the gastrointestinal tract. Next, they are converted by hepatocytes, are removed by the kidneys: 90% of urine and 4% as part of bile.

When orally use, ventoline is quickly absorbed by the walls of the gastrointestinal tract. Its maximum blood concentration is achieved within the first 2 hours after the reception. It decreases 5-6 hours. From the body, the drug is removed mainly with the urine during the day. Instructions of Ventoline contains data on the period of its complete removal from the body - 72 hours.

Forms of release

The tool is produced in different forms:

Ventolin aerosol. The inhaler is made of aluminum, equipped with a dosing device from plastic, protective cap. The dosage suspension has a white color. Aerosol is sold in cardboard packaging. Inhaler is convenient for everyday socks
Ventoline nebula for inhalations. Polyethylene nebones are soldered with each other, sealed in laminated foil. The drug is sold in cardboard packaging. Drug solution has a transparent color. The contents of the ampoules are used using a nebulizer, which is inferior to the mobility to other output forms
Tableted Ventoline. For convenience, produced in three interpretations: 10-20-50 tablets. Blisters are packaged in cardboard packaging. Tablets Ventoline Round, end surface is flat. The chamfer is on both sides, risk - with one. Dignity: Tablets can be worn with you
Ventoline syrup. Yellow-orange liquid with taste and smell of strawberries. Glass bottle is packed in a cardboard box. Ventoline in the form of Syrope is very well suitable for the treatment of children.

Mode of application

Acquaintance with the instruction on the use of Ventoline is necessary for productive therapy:

Spray can

The cost of such a spray fluctuates around 140-160p / bottle.

Used to treat children over 2 years old and adults. If the patient does not coordinate the breath and moment of spraying Ventoline, then for effective inhalation he needs a spacer. Children of preschool age shows apply aerosol ventoline through the Bebikhaler device. Dosage to reduce spasms: adults - 0.1-0,2mg / 4 times a day, child - up to 0.1-0,2mg / 4 times a day

Price of the drug from 270 to 350r / tutu / 10 nebul.

The tool is unacceptable to use for injection procedures before opening shake. It is used exclusively by inhalation through a nebulizer in the ventilated room. If you need to use for children under 18 months or for long-term inhalations (longer than 10 minutes) it is permissible to dilute sodium chloride solution (0.9%) 1: 1. The dosage of one ventoline nebuly for inhalations in the instruction is 2.5 mg of the active substance salbutamola. For the treatment of bronchospasms, there are enough 2-inhalation procedures per day, regardless of age. At home, it is better to connect Ventoline with saline in proportion of 1: 1. Hospital treatment allows an increase in dose to 40 mg / day across the medical prescription. With a strong obstruction of Bronchi Ventolin not divorce.

Tableted Ventoline

The average price is 140 rubles.

It is used inside 30 minutes before meals, not chewing. Dosage tablets containing 2 or 4 mg salbutamola: for adults - 2 tablets / day, children - 2 times 0.5 tablets / day. Detailed recommendations should give a doctor. Dosage of tablets containing 8 mg of salbutamola: for adults - 1 tablet every 12 hours, children are identical.

The cost of the bottle 50p.

A solution of 150 ml is used inside 30 minutes before meals. Dosage for adults 4ml / 3 reception, children from 2 to 6 years old - 1 ml / 3r, from 6 to 12 - 2 ml / 3r and from 12 years not more than 4ml / 3 times a day. Adults in acute necessity can be increased by a dose of up to 8ml, but not more than 3 receptions at 24 hours. A 50 ml solution is used orally 30 minutes before meals. Dosage medication for adults: 2 ml / 2r per day, children are not more than 2 ml per day.

During pregnancy and gv

Reception of the drug Ventoline during pregnancy, even starting from 3 weeks, not clinically studied. That is why, admission should be carried out in the third trimester of pregnancy only in the case of acute need. In the first trimester, and throughout the term of pregnancy, Ventoline can cause tachycardia from mother and fetus, as well as Gaperglycemia. There are cases when generic activity weakened, but confirmed statistically this data or not unknown. Doctors have the following disorders when taking Ventoline during pregnancy:

Pulmonary edema
Fallen blood pressure.

During the breastfeeding period, Salbutamol enters the maternal milk, and in effect and in the body of the newborn. Clinically not studied, it affects it positively or harm. Nursing mothers are not recommended to prescribe ventoline reception, will be exception, only when women's health priority salbutamola reaction on the kid's body.

Contraindications and precautions

For safe use, fixed dosages must be observed, and also familiarize yourself with the list of restrictions for receiving the drug. The following contraindications are indicated in the instructions for the use of Ventoline:

Premature birth
Tahiaritmia
Threatening abortion
Heart failure
Allergic reaction to any component component
Complicated pregnancy
Therapeutic use of children up to 18 months
Arterial hypertension
Feochromocyt
Streetoxicosis
Decompensated diabetes mellitus.

Although Ventoline and not from the group "Hormones", still do not engage in self-medication, refer to experts for advice and appointment.

Side Effects and Overdose

Noticing the manifestation of the following side effects, Ventoline's reception should be stopped and refer to a specialist for advice.

Adactions to the drug:

Increasing headache
Noticeable trembling in hand
Paradoxical bronchospasm
Heartbeat disorders
Expansion of vessels
Restless Son.
Failure of taste receptors
Dryness and irritation of the mucous membranes of the mouth and nasopharynx
Epidermal rash
Allergy: arterial hypotension and bronchospasm, angioedema edema, urticaria, collapse and decreased blood pressure
Hypokalemia
Hyperactivity in children
Significant cramps.

To quickly relieve and get rid of the specified symptoms, you should contact a specialist for help, and in some cases call an ambulance care.

Ventoline overdose symptoms:

Muscular trembling
Vomit urge
Causes
Tachycardia
Lower hell
Hallucinations
Excitation
Nausea
Respiratory alkalosis
Lowering phosphate levels
Hypokalemia
Changing blood, at the level of cells - leukocidosis
Lactate acidosis.

In order to avoid such violations and symptoms, medical prescriptions should be adhered to. Most often, the course of treatment is appointed for a week or two. Do not experiment with dosages, especially children.

Conditions and shelf life

Ventoline Nebules Instruction provides for the shelf life - 2 years. After opening the foil, it is necessary to use for 3 months. Tablets are used for 3 years from the date of production. Inhaler with ventoline is suitable for two years, if there are no freons in its composition. Otherwise, it can be used for 3 years. Ventoline Syrup is 2 years.

Regardless of the form of the issue, it is necessary to store the drug in darkened and inaccessible to children, at an air temperature not higher than 30 0 C. Do not freeze. The use of the remnants of the drug in the nebulizer is not subject to.