Zovirax is an antiviral drug that is intended for outdoor use.
The tool is a homogeneous white mass of soft consistency without extraneous particles, which has a characteristic odor. This is an effective immunostimulator used externally for the treatment of infections caused by numerous viruses.
On this page you will find all the information about Zovirax: complete instructions for use in this medicinal medium, average prices in pharmacies, full and incomplete analogs of the drug, as well as the reviews of people who have already used the ointment Zovirax. Want to leave your opinion? Please write in the comments.
Clinical and Pharmacological Group
Antiviral preparation for outdoor and local application.
Conditions of vacation from pharmacies
Released without a recipe.
Prices
How much is Zovirax? The average price in pharmacies is at the level of 190 rubles.
Release form and composition
The drug Zovirax releases the pharmaceutical Corporation Glaxo Smith KLINE Pharmaceuticals SA:
- in tablets;
- in the form of cream 5%;
- eye ointment 3%;
- and the lyophilisate for the preparation of a solution in ampoules. For 5% of the concentration of Zovirax in the form of cream is denoted by Zovirax 5.
The tool produced by the company in the form of ointments is called the eyelaska eye. Powder lyophysial is designed to prepare a solution for injections, it is called simply - zovirax in ampoules. Krem Corporation produces in plastic bottles with a 2-gram dispenser. Cream Zovirax is a white homogeneous mass, produced in aluminum tubes of different volumes: 2 g, 5 g and the biggest - 10 g.
Pharmacological effect
The existing substance Zovirax is a representative of the pharmacological group of drugs antiviral connections. The antiviral effect is that after the arrival of aciclovir in the cell infected with a virus, under the action of tiimdiginalinase (the enzyme that appears only inside the cell infected virus) turns into active metabolites.
They are embedded in DNA (deoxyribonucleic acid) of the virus, which leads to a failure of its subsequent replication (doubling the threads) and impaired intracellular reproduction of viral particles. Cream Zovirax has the maximum antiviral activity against a simple herpes virus Type 1 and 2, Epstein-Barr virus, cytomegaloviruses, causative agent losing (VARICELLA ZOSTER).
Indications for use
What does Zovirax help? Here are the main indications for use:
- The eye ointment is used in the treatment of keratitis, eye disease caused by 1 and 2 types of herpes virus.
- The cream is used for the therapy of herpetic infections of the skin and mucous membranes, as well as for.
In the form of injections and tablets, Zovirax is prescribed at:
- treatment "" (chickenpox);
- treatment of infections in newborns caused by herpes viruses 1 and 2 types;
- therapies of infections that are caused by 1 and 2 types of herpes virus;
- prevention of herpetic infections;
- prevention.
What is the ointment different from the cream?
Their impact on mucous membranes and skin is equally, but the cream cannot be used to treat mucous membranes and eyes. It is intended for the treatment of infection on the face and lips caused by Herpes Labalis - a virus of a simple herpes.
Contraindications
Contraindications include excessive sensitivity to both the drug as a whole and its active substance. With manifestations of an allergic nature, the drug is canceled.
Application during pregnancy and lactation
Pregnancy requires a neat relationship to the health of women and the fetus. Therefore, during pregnancy, the drug although it can be appointed with appropriate indications, but its use is carried out under the supervision of the attending physician.
During breastfeeding, the drug may fall into breast milk, and the child also receives a certain dose of the active substance (not more than 0.03%). For this reason, the assignment of Zovirax during lactation should be appointed with extreme caution.
Instructions for use
In the instructions for use, it is recommended that the Zovirax cream is recommended to apply 5 times / day (approximately every 4 h) with a thin layer on affected and bordering areas of the skin and mucous membranes.
- The duration of treatment is at least 4 days. In the absence of healing, treatment can be continued to 10 days. In the event of preserving the symptoms of the disease more than 10 days, you should consult with your doctor.
The cream is applied by either a cotton swab or clean hands to avoid additional infection of the affected areas.
Instructions for eye ointment
Adults and children preparation in the form of a strip of ointments of 10 mm long should be placed in the lower conjunctival bag. The multiplicity of application is 5 times / day with an interval of about 4 hours.
Therapy should be continued for another 3 days after healing.
Side effects
Side effects can be in the form of allergic or local reactions:
- Allergic reactions - angioedema edema;
- Local reactions - blepharitis, conjunctivitis, burning, point keratopathy (disappear independently).
Overdose
Overdose when using the drug Zovirax in this form is not possible, because the ointment does not have the ability to systematically affect the body.
special instructions
- With pronounced manifestations of herpes of the lips, it is recommended to consult with the doctor.
- In the treatment of genital herpes, it is recommended to avoid sex contacts or use condoms, because The use of aciclovir does not prevent the transmission of the virus sexually.
- To achieve the maximum therapeutic effect, it is necessary to apply the drug at first signs of the disease (burning, itching, tingling, feeling of tension and redness).
- Patients with immunodeficiency in the treatment of any infectious diseases should follow the recommendations of the doctor.
- Cream is not recommended to apply the mouth and eye mucous membranes, because Perhaps the development of local inflammation.
Medicinal interaction
No significant drug interactions when using the drug did not detect.
The acyclovir is displayed in the urine unchanged due to the channel secretion. All means with a similar way of elimination can increase the concentration of acyclovir in the blood.
According to WHO statistics, by 50 years, two thirds of the inhabitants of the planet are infected with herpes virus. But the disease is not manifested at all. Some may not guess that the virus is sleeping in the body. This is due to the peculiarities of the life cycle of the pathogen.
Why this virus is incurable
Zoviraks acts on most of the types of herpes virus, and to the family of alfairereviruses, there is a special activity. These include three types of pathogens:
- simple herpes 1 type (WSV-1) - manifests itself on lips, sometimes on the genitals;
- simple herpes 2 types (VVG-2) - causative agent of genital herpes;
- herpes 3 types - Variscel-Zoster virus - a chickenpox causative agent in children and shingly by adults.
Therapeutic effect applies to the following pathogens:
- epstein Virus - Barr;
The virus penetrates through the mucous membranes and heads through the nervous fibers in the spinal ganglia. There he is freed from his shell and embeds his DNA into the nucleus of the nervous cell. The genetic material will be there until a favorable moment.
Many people are long asymptomatic carriers. But with a decrease in immunity, the body loses control over the virus, and that in reverse order of nerve cells is sent to the epithelium of the lips. The virus penetrates into the cells, adjusts them to the synthesis of own particles. In each epithelial cell, several thousand viruses are replicated. During their output, they capture part of the cell membrane to create their own shell. It damages the cage and leads to her death.
All therapeutic measures are aimed at the destruction of viruses that began to replicate in epithelial cells. DNA particles that remained in nuclei nuclei are securely protected from drugs and the immune system. The body cannot direct aggression against itself, so the virus remains in it forever.
Even a chickenpox transferred in adulthood in an adulthood under favorable conditions can manifest itself in the form of a shearing linga - typical herpes rashes in the course of intercostal nerves.
Features of the active substance
The acyclovir is the active in the composition of Zovirax. This is an analogue of the normal component of the DNA of purine nucleosid deoxyiguanosine. The development of the drug belongs to the pharmacologist from the US Gertrude Elaion, which received the Nobel Prize for this.
The mechanism of action is associated with the embedding of acyclovir due to similarity in viral DNA. This is accompanied by the blocking of the DNA polymerase enzyme, which is manifested by stopping the synthesis of this acid.
The effect of the drug selectively. Driving on viral particles, it does not affect the synthesis of normal DNA in the body.
Pharmacological properties of ointments, cream, tablets and solutions
Zovirax is produced in several pharmacological forms. Their appearance and dosage are presented in the table.
Table - the main forms of "Zoviraks"
Each of the means has its own specifics.
- Cream. It is used externally, locally on the rash area. Affects epithelial cells. When re-applying, the system absorption is minimal. It helps to accelerate the healing of acne, reduces pain, prevents the appearance of new rashes.
- Ointment When applied to the cornea is quickly absorbed. Therefore, in the intraocular fluid, there is a noticeable increase in the concentration of acyclovir. Excreted by the kidneys.
- Pills . Quickly absorbed in the intestines. After four hours, it reaches high plasma concentrations. The content in the spinal fluid is 50% less than in the blood. Most of the medication is excreted by the kidneys unchanged.
- Infusion solution. With intravenous infusion, the maximum concentration is recorded in an hour. Half-life from two to three hours. It is excreted by filtration by renal glomers and secretion in the tubules.
The removal of the medicine through the kidneys requires a dose correction in renal failure. According to research, at the same time, the semi-anniversary of the drug can last up to 19 hours.
There is also a combined drug cream Zovov Duo-Active. In addition, in addition to acyclovir, hydrocortisone hormonal component is included. Its addition gives the cream the following properties:
- anti-face;
- anti-inflammatory;
- vasoconstrictor;
- antiallergic.
The medicine is local. Hydrocortisone is not able to penetrate the systemic bloodstream and have an oppressive effect on adrenal glands.
In what cases can be used
Indications for the use of Zovirax include cases of infection with a virus of a simple herpes 1 and 2 types, as well as manifestations of herpes Zoster, Epstein-Barra virus. But there are some features.
- Cream. It acts exclusively. Therefore, it cannot be used as a monotherapy. The action of local means is complemented by tablets. The cream is used in the rashes of the cold on the lips, on the nose, with genital herpes. Dentists prescribe acyclovir under herpetic stomatitis. For treatment with papillom, the cream does not apply, the cause of the disease in this case, the human papilloma virus, to which Zovirax does not work.
- Ointment It is used locally for the treatment of keratitis, conjunctivitis caused by WSV-1. Barley is not included in the spectrum of readings. This pathology is a consequence of infection with golden staphylococcus.
- Pills . Used for the treatment of skin manifestations of WSG-1, WSV-2, as well as to prevent recurrence in people with normal immunity or immunodeficiency. Effective in chickenproof therapy, hailing deprived. It is used in neurology in patients with neurutic facial nerve and other localizations in suspected herpetic nature of the disease. You can use HIV-infected and people after bone marrow transplantation.
- Solution for infusion. A list of readings is the same as for tablets. But often it is a heavier disease manifestation. Also, the solution can be used in newborns infected with herpes.
Instructions for the use of Zovirax: Selection of dosage
The cream is applied to the places of rash by a thin layer, but do not rub in to avoid infection of neighboring tissues. You can use four to six times a day. The course lasts from five to ten days. It is important to begin treatment with the emergence of the first signs of infection in the form of edema, itching and burning. The outcome of the disease can be snubs on the lips, which are a sign of the deficit, and not the remnants of herpes.
The treatment of the eye ointment is carried out before the disappearance of symptoms plus for three more days. It is squeezed with a length of 1 cm in a conjunctival bag five times a day. It is important to observe the time interval at four hours.
Using tablets maybe in adults and children after a year. They are accepted while eating, drinking a glass of water. Dosing depends on the purpose of the admission and immune status of the patient. This is described in more detail in the table.
Table - Treatment with tablets "Zoviraks"
| Purpose of use | Dosage |
|---|---|
| Treatment of WSG | - 400 mg every 4 hours, except sleep time; - course 5 days; - during immunodeficiency dose for each reception double |
| Prevention of RPV recurrences with normal immunity | - 200 mg 4 times a day or 400 mg 2 times a day; - the duration of the course is individual, but it is interrupted by 6-12 months to evaluate effectiveness |
| PREVENTION OF THE FLEX OF THE WRV in patients with reduced immunity | - 200 mg 4 times a day; - after bone marrow transplantation of 200 mg 5 times a day; - the duration of the course is individual |
| Treatment of chickenpox and slimming losing | - 800 mg 5 times a day for 7 days; - in children over 6 years 800 mg 4 times a day; - Children 2-6 years 400 mg 4 times a day; - up to 2 years 200 mg 4 times |
| Treatment with pronounced immunodeficiency | - 800 mg 4 times a day; - In some cases, the tablets are replaced by intravenous administration of the drug |
Children accurate dosage can be calculated by weight of the body. 20 mg / kg of weight is recommended, but not more than 800 mg per each of the four techniques. Patients with obesity Adjustment of the dose is not required. In renal failure, the dose is reduced, and the elderly requires compliance with the drinking mode with a flow of at least 1.5 liters of fluid per day.
The solution for intravenous infusions must be properly prepared. To do this, a 10 ml of 0.9% sodium chloride or water for injection is introduced into the ampoule with the lyophilisate. The ampoule is scolded until the content is completely dissolved. Imagine the solution is needed dropwise within an hour. To do this, use a special infusion pump in which you can set the required speed. Or the solution is divorced further and is injected with a dropper. The calculation of the dosage is carried out in each case individually. Course for five days.
The shelf life of Zovirax in the form of a cooked solution is not more than 12 hours. When clouding, it cannot be used.
Unwanted effects
Side effects can be observed from the use of any dosage form.
- Cream. Skin itching, a feeling of burning, when used from genital herpes - vulvit. With a reduced immunodeficiency, a candida fungus may appear, which leads to a thrush. But this is not a consequence of treatment with cream.
- Ointment Side effects are manifested by blufaritis, burning, conjunctivitis.
- Tablets and mortar. Dyspepsic phenomena, increased hepatic enzymes in the blood, headache, allergies, fatigue. Rarely observed anemia, leukopenia, dizziness. In patients with severe kidney pathology, cramps and confusion may appear at large doses, coma is possible.
Overdose symptoms include more pronounced side effects. Treatment involves the conduct of hemodialysis and maintaining the vital functions of the body.
From contraindications - individual intolerance to the drug. Caution is used in dehydration and renal failure.
Pregnancy is not a contraindication, but it is necessary to use Zovirax after consulting a doctor. With breastfeeding, treatment of even 200 mg per once a day leads to the appearance of traces of acyclovir in milk. The medicine is safe for newborns, but it is necessary to approach its use.
Zovirax is one of the trade names of the drug acyclovir. There are analogues of ointment "Zoviraks" according to the active substance. In pharmacies you can find preparations with the following names:
- "Acyclovir Vishf";
- "Herpeblock";
- "Geviran";
- "Azigrupin".
Zovirax is produced in the form of tablets, ointments and injections. But for all varieties of the drug, it is important to comply with the right storage conditions and follow the shelf life indicated on each package. We will tell how many years Zovirax remains suitable for use, and in what temperature conditions it must be stored between the receptions.
The shelf life of the drug
The shelf life of the drug is calculated since the manufacture of a medicine, and not from the day when it acquired, discovered or began to apply the patient. Therefore, the packaging always indicates the date of manufacture up to day.
Is Zovirax she is shelf life, how to find out where it is specified?
Zovirax has a limited application period, the shelf life is indicated on the package or in the instructions for use (sometimes, and there, and there). But in order to calculate it correctly, it is necessary to know the date of manufacture of products - as a rule, it is indicated on the side of the packaging. From the moment of creating medicines, we must recommend the recommendation period:
- Eye ointment - 5 years without opening a tube, 1 month after discovery;
- Cream for outdoor use - in aluminum packaging 3 years, in a plastic bottle with a built-in dispenser - 2 years;
- Ampoules for the preparation of the solution - 5 years;
- Pills for oral use - 5 years.
Is it possible to use the drug if the term ends in 5-10 days?
Yes, doctors allow the use of such medicines, since their shelf life has not expired, which means they have retained their pharmacological properties with a 99% guarantee. However, it is impossible to use Zovirax if a) changed the color or consistency of the drug, b) in the bottle with the drug there was a precipitate, c) the packaging is damaged and nonhygienic.
Deadlines before autopsy and after opening the drug
The shelf life of the printed zovirax depends on the form of release. It is noteworthy that not always on the packages indicate the recommended service life, but should be guided by such temporary periods:
- Tablets Zovirax - up to 12 months
- Mazi - 6 months,
- Eye ointment - 28-30 days,
- Ampoules - use in 24 hours After opening the solution.
What happens to the medicine over time?
The shelf life is a kind of guarantee that the medicine during the specified time remains effective in the struggle of the disease. Over time, individual components of medicines may lose their properties that negatively affects the effectiveness of the drug Zovirax.
How to understand that the drug is defective and is not suitable for use?
Carefully examine the packaging of the zovirax, it should not be damaged, have extraneous shades, to be burnt away from sunlight or damaged. If the pills, ointment or solution lost the initial species, darkened, changed the consistency, cannot be used.
The drug ended the shelf life, whether it is possible to use it. Can it harm the use of overdue?
How to keep zovirax at home
Store in an inaccessible place for children at a temperature not higher than +25 degrees, for ampoules per package is allowed to +30. The place must be protected from direct sunlight and dry.
Is it possible to store in the refrigerator and freezer
Zovirax does not require compulsory storage in the refrigerator, but it can be stored in the side shelf. Storage in the refrigerator is prohibited.
What storage conditions Zovirax is "afraid"
The medication may faster, if you leave it in a place where the sun regularly shines (even through the glass), the moisture and dampness also affect it. Low and too high temperatures (below zero and above thirty degrees) negatively affect the preparation state.
Treatments-analogues:
Acyclovir
Conditions for storing the drug in pharmacies and clinics
sunlight
All drugs are afraid of sunlight. Ultraviolet is a catalyst for chemical and physical processes in medications of various forms of release. It is impossible to recognize the medication on time "damage", so the drugs are stored exclusively in a dark place (in a closet door) or in the shelves under glass, where the sun's rays do not fall. All drugs are stored in original packaging; If the packaging is no longer complete, then the remaining drugs are still put in cardboard protective packaging in the pharmacy.
Humidity
Most drugs in the form of tablets, capsules, hygroscopic powders, they are easily absorbed by moisture, because of which their pharmacological properties change, so in pharmacies they are watched.
Air access
With a violation of the tightness of the factory packaging, evaporation of the active component of the drug, its oxidation or interaction with other chemicals is possible. As a result, the effectiveness of the means is reduced.
Pharmacy guarantees dry, dark and cool place for Zovirax.
Medicines for different applications are stored separately.
Application area
Viral infections for which the lesion of the skin and mucous membranes is characteristic.
Form release
Available in the form of ointments (soft, homogeneous, almost white with a weak characteristic odor, tablets (blue, flat, irregular polygonal shapes) and injections (on white white mass). Produce a pharmacological company from different parts of the world, in Russia you can find a domestic drug in Rossi , as well as medicines from the UK.
What is zovirax
This is an antiviral drug that is used to treat diseases caused by a variece virus, sold without a recipe.
Thank you
The site provides reference information solely to familiarize yourself. Diagnosis and treatment of diseases must be under the supervision of a specialist. All drugs have contraindications. Consultation of a specialist is obligatory!
Drug Treatment Zovirax. Available in several dosage forms, and is a convenient immunostimulator, which is used, both externally and local and inside, in the form of tablets or injections. The action of Zovirax is directed against viruses, including those common as herpes (simple and genital), chickenpox, epstein-barra and cytomegalovirus. Accordingly, Zovirax preparations are used to treat infections caused by listed viruses, including chickenpox in children and adults, herpes (on the lips, genitals), etc. Also, the drug is used for therapy of patients with acquired immunodeficiency syndrome (AIDS), as well as to maintain normal well-being and resistance to infections in people who have undergone bone marrow transplantation.Forms of the release and title of the drug
The zovirax drug is produced by the pharmaceutical Corporation Glaxo Smith Kline Pharmaceuticals SA, in the following dosage forms:1. Pills.
2. Cream 5%.
3. Eye ointment 3%.
4. Lyophilisate for making a solution in ampoules.
Zovirax in the form of a cream due to a concentration of 5% often indicate how Zovirax 5.. And the preparation in the form of ointments is simple Zovirakse Eye. The lyophilisate powder intended for the preparation of the injection solution is called Zovirax in ampoules.
The cream is produced in plastic bottles with a capacity of 2 g, as well as in aluminum tubes in 2 g, 5 g and 10 g. The drug is a homogeneous weight of white.
Zovirax tablets are painted white, have a round shape and the inscription GXCl3 on one side. One package contains 25 tablets.
Zovirakse The eye is a homogeneous ointment (without lumps and grains) with an oily texture, which has a characteristic smell, and painted in white translucent color. Eye ointment is produced in aluminum tubes for 4.5 g.
Zovirax lyophilisate is available in 250 mg ampoules, and looks in the form of a powder, which is shred in a porous cake. In one package there are 5 ampoules with lyophilisate.
Structure
As an active component of any dosage form, Zovirax includes an acyclovir substance with antiviral activity. In the cream, the concentration of acyclovir is 5%, or 50 mg for 1 g. The tablets contain 200 mg. In the eye ointment - 3%, or 30 mg for 1 g. In the lyophilisate - 250 mg per vial. As auxiliary components, each dosage form contains its chemical compounds that you need to know people suffering from allergic reactions. To avoid enumeration of all components of various dosage forms of Zovirax, we will dwell only on those that have a property to cause allergic reactions. So, potential allergens among the aids in Zovirax are as follows: - In the cream - alcohols, paraffin, sodium lauryl sulfate and dimethicone;
- In the tablets - starch, povidone 30 k, lactose;
- In ointment Eye - White Vaseline;
- In the lyophilisate - sodium hydroxide.
Therapeutic effects and effects
Zovirax destroys the following viruses:- Herpes Simplex type 1 and 2;
- VARICELLA ZOSTER (chickenpox);
- EBV (Epstein Barra);
Zovirax after admission to the human body enters cells affected by the virus. After that, the virus enzyme called "Timidinkinase" conducts a number of chemical transformations of the active component of the drug, the result of which is the formation of acyclovir trifhosphate. Tryphosphate acyclovir enters into interaction with another enzyme - DNA polymerase, which performs the synthesis of the DNA of the virus. As a result, a trifosphate acyclovir is in the composition of the newly synthesized DNA of viruses, which is not present in the structure of the genome. And thus, the finished DNA of the virus turns out to be defective, that is, not suitable for further reproduction and operation of the microorganism. As a result of the formation of such a defective genetic material, viruses lose the ability to multiply, and dying after the deadline for their life, without damaging new healthy cells, and does not lead to the chronization of infection.
Such a mechanism of action is called a "false substrate", since instead of the necessary component, the enzyme is proposed "cheating", very similar to the desired substance. The enzyme uses a "deceiving" that cannot perform certain functions, and as a result, the entire system becomes a non-visual. It is urgently to say that such a mechanism of action is similar to the installation of a defective part in a complex mechanism that will not work with it.
Zovirax has a high selectivity, and acts only on cells that are infected with viruses without affecting normal and healthy. That is why this drug is safe for healthy cells of the human body, which determines its low toxicity. If you use a means of long-term courses or very often, the resistance of viruses to the drug can be formed, after which it will fully lose the effectiveness.
Indications and contraindications
Cream is used to treat herpetic skin infections and mucous membranes, including lips. The eye zovirax is used to treat keratitis caused by herpes viruses 1 and 2 types.
Indications for the use of zovirax in the form of tablets and in ampoules are the same. So, inside and in the form of injections, Zovirax is used to treat the following states:
- treatment of infections caused by herpes viruses 1 and 2 types;
- prevention of herpetic infections;
- treatment of chickenpox;
- treatment of infections caused by herpes viruses 1 and 2 types, in newborns;
- prevention of cytomegalovirus infection.
Relative contraindications to the use of zovirax in the form of tablets or in ampoules are states of dehydration, renal failure and neurological symptoms. With these states, Zovirax can be applied, but with caution and under control over the patient's condition.
Tablets, injections, cream and eye ointment Zovirax - instructions for
Application
Dosing mode and the duration of treatment courses when using various forms of the drug Zovirax are excellent. Therefore, we consider the use of each form of the drug separately. Pills
Tablets need to be littered with clean water in an amount of 200 ml (1 cup). Take a dependence on food.Adults take tablets for 1 pc. (200 mg) 5 times a day for the treatment of infections caused by herpes virus. The duration of the course of therapy is 5 days. If intestinal suction is impaired in diseases of the gastrointestinal tract, or a person suffers from strong immunodeficiency (for example, after a bone marrow transplant), then the dosage of the tablets Zovirax increases by 2 times, that is, it is accepted 5 times a day 2 pcs. (400 mg). Children at the age of 2 and older are taken by Zovirax in adult dosages in the treatment of herpetic infections. And the children under 2 years old take the drug half of the adult dose.
When developing a viral infection, for the first time, it is necessary to start receiving Zoviraks as early as possible. If the recurrence of chronic infection takes place, then you can start the reception already when the "forerunners" appears, or single elements of rash.
In order to prevent recurrence of herpetic infections, Zovirax 1 tablet (200 mg) is taken 4 times a day, or 2 tablets (400 mg) 2 times a day. However, with a sufficient duration of remissions, it is possible to reduce the preventive dosage of up to 1 tablet 3 times a day, or even 1 tablets 2 times a day. If such low doses lead to a good effect, then it is not worth an increase. The course of treatment must be carried out at periodic intervals of half a year - a year. The duration of the prophylactic course of therapy depends on the severity of the flow of infection and the risk of developing aggravation. For the prevention of herpetic infections, children aged 2 years and older are taken by Zovirax in adult dosages. And the children under 2 years old take the drug half of the adult dose.
The treatment of chickenpox and a sliding linguing lies in the reception of Zovirax by adults, 4 tablets (800 mg) 5 times a day, during the week. Children take the drug in an adult dose after reaching the 6th age, 2 tablets 4 times a day at the age of 2 - 6 years, and 1 tablet 4 times a day at the age of 2 years.
When using Zovirax for the treatment of elderly people, creatinine clearance must be regularly monitored. With the development of renal failure, it is necessary to reduce the dose. Older people should drink enough water against the background of taking tablets.
People suffering from renal failure with filtration coefficient (QC) at least 10 ml / min can take zovirax in conventional doses. If the KC is less than 10 ml / min, then the dosage is reduced to 1 tablet 2 times a day, in the treatment and prevention of herpetic infection. Treatment of chickenpox and haying depriving in patients with renal failure is carried out according to the following doses: with QC less than 10 ml / min to 4 tablets 2 times a day, with QC from 10 to 25 ml / min to 4 tablets 3 times a day, and at QC More than 25 ml / min in the usual dosage (4 tablets 5 times a day).
Zovirax in ampoules (lyophilisate)
The lyophilisate is dissolved, and the finished drug is introduced intravenously, drip. The dosage is calculated by body weight. Adults receive zovirax at 5 mg / kg every eight hours, in the treatment of herpetic infections and wind sieves. The treatment of herpetic encephalitis in adults requires a dosage of Zovirax at 10 mg / kg every 8 hours. If the patient suffers to obesity, the resulting calculated dosage of the drug must be reduced. Reducing the dose is produced to a human level of the same growth with normal weight. For example, a woman's growth is 170 cm, and the weight is 100 kg. In this case, the dose must be established on the basis of the accepted growth and weight standards, that is, to count not by 100 kg, but by 69 kg, which are the norm for a woman with an increase of 170 cm. Weight and growth standards are determined by tables. The duration of therapy is 5 days. Older people with renal failure should receive zovirax in a reduced dosage. In the intravenous introduction of Zovirax for the prevention of viral infections - dosages are the same as for treatment, but the multiplicity of administration is once a day. The duration of preventive drug administration is determined by the risk of recurrence.
Children can receive intravenous injections from birth. Dosages are calculated from the surface area of \u200b\u200bthe body. Treatment of herpetic infections is carried out in a dosage of 10 mg / kg every 8 hours. The duration of the course of treatment is 10 days. The windmill is treated by Zovirax in a dose of 250 mg / m2, which is introduced every 8 hours. If the child suffers to renal failure, the dosage must be reduced.
A solution for intravenous administration is prepared immediately before infusion. The entire volume of the solution is not slower than 1 hour. The lyophilisate is dissolved in water for injection or sterile saline. One ampoule of lyophilisate is dissolved in 10 ml of water, and 2 ampoules in 20 ml. The solvent is brought into the ampoule and gently stirred until the formation of a transparent solution. The finished solution is transferred to the dropper. If flakes appeared or dropped crystals - the drug cannot be used.
Eye ointment
Squeeze out 1 cm ointment from a tube and deposit under the lower eyelid. Ointment lay 5 times a day. The course of treatment lasts until the healing of Keratitis, and continues for the prevention of three days. After applying ointments, a slight burning sensation can develop, which will independently pass after a while. Throughout the use of ointments, Zovirax should be abandoned by contact lenses.Cream Zoviraks.
Skin areas with herpetic rashes or windmills are treated with Zovirax cream 5 times a day. The course of use is 4 days, which can be extended to 10 days with slow elimination of symptoms of viral infection. The cream is applied and distributed over the surface of the skin or mucosa with a thin layer, capturing adjacent healthy sections. In order not to transfer the infection to healthy areas of the skin, apply the cream with clean hands or tampon.It is better to begin the use of a cream when the primary symptoms of viral infection appears - the sensation of burning, itching, redness and swelling of the skin or mucous membranes. In the treatment of herpes on the lips, it is necessary to avoid the drug in the mouth and eyes. In the treatment of genital herpes, sexual abstinence must be observed.
Zovirax from herpes
From herpes on the lips of Zovirax in the form of cream, it is necessary to begin to apply when the feeling of burning and tingling on the skin appears, without waiting for the rash of bubbles. In this case, herpes may not jump at all. If this period fails, start using Zovirax as soon as possible - then herpetic rashes will be held within 2 - 4 days. Do not be lazy to smear herpes every 4 hours, except for the night recreation period, as it gives a tangible effect. If herpes on large lips, then the zovirax cream, which is applied to the lips local, you can add tablets that can be added within 5 days, 1 pcs. 5 times a day.
Application during pregnancy and children
The drug Zovirax is safe and low-toxic, therefore allowed to use even newborn children. However, the pregnancy period is very important in the life of a woman, so the use of any drugs at this time is associated with the assessment of potential risks. Consider the established practices for the use of this fund in pregnant women and children in the appointments of doctors.Zovirax during pregnancy
Manufacturers indicate that suction to the systemic bloodstream when using eye ointment and Zovirax cream is quite slightly, so it will be practically zero. However, due to the lack of scientific research, which for obvious reasons were not conducted on pregnant women, the manufacturer considers it to specify this. In practice, cream and eye ointment Zovirax can be applied by pregnant women to treat genital herpes, rashes on lips or skin, since the drug does not bear the negative effect, and the manufacturer simply should indicate in the instructions on the absence of experience.
But the reception of Zovirax inside in the form of tablets or intravenous infusion with pregnant women requires care of caution. It is better to use drugs only when the benefits are above all possible risks. It should be known that during the use of Zovirax in pregnant women did not reveal the negative effects of the drug on the fruit. But these observations were not combined into the system and did not acquire the nature of the scientific data that can be indicated in the official instructions.
Zovirax Children
Eye ointment It can be used to treat herpetic keratitis in children from birth. Ointment 1 cm long laying under the lower eyelid to 5 times a day. Use the tool must be full of eye healing.
Cream It can also be used to treat herpetic rashes, including on lips, or chickenpox with children, from birth. To do this, cream is applied by a thin layer on the affected area, a little exciting healthy skin or mucous membrane, with a cotton swab. The duration of use depends on the rate of recovery, and is 4 - 10 days.
Pills Children also apply from birth to treat and prevent herpetic infection, including lips, and windmills. Children over 2 years old receive Zovirax for the treatment of herpetic infections, in the dosage of 1 tablet 5 times a day. The course of treatment is 5 days. Children under 2 years old take 0.5 tablets 5 times a day, for the treatment of herpetic infections.
Prevention of recurrences of herpetic infections in children over 2 years old can be conducted by Zovirakse in the following schemes: 1 tablet 4 times a day, or 2 tablets 2 times a day. With a low risk of relapse, you can reduce the prophylactic dose of up to 1 tablet 3 times a day, or even 2 times a day. Children under two years for the prevention of herpes relapses receive Zovirax 1 tablet 2 times a day, or even 1 time per day.
The treatment of windmills in children is carried out within 5 days. The dosage for children over 6 years old is 4 tablets 4 times a day, for children 2 - 6 years old - 2 tablets 4 times a day, and for children under 2 years old - 1 tablet 4 times a day. A single dosage of Zovirax for children in the presence of severe somatic pathology can be calculated precisely by weight of the body - 20 mg per 1 kg. However, the one-time dosage calculated by weight of the body should not exceed 800 mg.
Injection Zoviraks. Apply for the treatment of herpetic infections, including encephalitis and chickenpox in children, from birth. Dosages are calculated from the surface area of \u200b\u200bthe body. Treatment of herpes infections is carried out in a dosage of 10 mg / kg, every 8 hours. The duration of the course of treatment is 10 days. The windmill is treated by Zovirax in a dose of 250 mg / m2, which is introduced every 8 hours. If the child suffers to renal failure, the dosage must be reduced.
Side effects
Ointment Eye and Cream Zovirax possess side effects in the form of local and allergic reactions, which are reflected in the table:| Organs and systems from which There are adverse reactions | Side Effects of Tablets and Injection Zovirax |
| Digestive system | Nausea |
| Vomot | |
| Increase in bilirin concentration | |
| Increase the activity of AST and Alt | |
| Hepatitis | |
| Jaundice | |
| Diarrhea | |
| Abdominal pain | |
| Blood system | Anemia |
| Reducing the number of leukocytes and platelets | |
| urinary system | Increase the concentration of urea and creatinine |
| central nervous system | Dizziness |
| Concision confusion | |
| Hallucinations | |
| Causes | |
| Drowsiness | |
| Coma | |
| Excitation | |
| Fire shakes (tremor) | |
| Psychosis | |
| Allergic reactions | Rash |
| Photosensitization | |
| Hives | |
| Itch | |
| Temperature | |
| Dyspnea | |
| Sweet Qincke | |
| Anaphylactic reactions | |
| Other systems | Necrosis at the injection site when the drug is injected under the skin |
| Tired | |
| Hair loss |
Tablets and injections Zovirax have a larger spectrum of side effects from various organs and systems, which are also reflected in the table:
Analogs
Today's pharmaceutical market there are analogues and synonyms for Zoviraks. Synonyms are preparations that contain as the active substance the same acyclovir. And the analogues are preparations that contain a different substance as a valid component, but have a similar spectrum of action and therapeutic effects.The synonyms of Zovirax include the following drugs:
- Acyclovir tablets;
- Tablets aciclovir Belupo;
- Tablets Acyclovir Forte;
- Tablets aciclovir-AKOS;
- Tablets acyclovir-acry;
- Tablets Acylostad;
- Vivorax pills;
- Virolex pills;
- Tablets Gerrers;
- Tablets Herpetad;
- Sursan pills;
- Tablets acyclovir Sandoz;
- The lyophilisate aciclovir-teva, the solution is introduced intravenously;
- Virolex lyophilisate, the solution is introduced intravenously;
- Medudir powder, the solution is introduced intravenously.
- Arvron capsules;
- Capsules of faith-ribavirin;
- Capsules Rebeatol;
- Ribavin capsules;
- Ribavirin capsules;
- Capsules Ribavirin Meduna;
- Ribavirin-vert capsules;
- Ribavirin-Lance capsules;
- Trivorin capsules;
- Ribavirin-SZ capsules;
- Capsules and pills Ribavirin-FPO;
- Capsules and pills Ribapeg;
- Tablets Valacyclovir;
- Tablets Valtarex;
- Tablets Valcitis;
- Wacrex tablets;
- Tablets Ribavirin;
- Pills ribamidil;
- Tablets Famvir;
- Vairova tablets;
- Tablets Minker;
- Valacyclovir-OBL tablets;
- Tablets of Famciclovir Teva;
- Concentrate viorazole, the solution is introduced intravenously;
- The lyophilisate ribavirin-lipint, suspension is accepted inside;
- The lyophilisate is zimevin, the solution is administered intravenously.
Cheap analogs
The following drugs and synonyms that are present at the pharmaceutical market of Russia are cheaper than Zovirax.
- ointment and tablets acyclovir;
- tablets and ointment acyclovir-acry;
- ointment and tablets acyclovir AKOS;
- cream acyclovir Belupo;
- vivorax cream;
- cream, Tablets and Virolex ointment;
- herring ointment;
- herpferon ointment;
- ointment acigerpin;
- acylostad cream;
- tablets of faith-acyclovir;
- powder for preparing a solution for herpesin injections;
- powder for the preparation of a solution for injections of the Medudir.
The incidence of herpes recently has become a rather pressing problem. The cause of its occurrence on the lips and mucous membranes is a viral infection and, as a result, a strong decrease in immunity. Very many patients who suffer from the manifestation of herpes on the lips are also concerned about the topics from the face at home. The solution to these health problems is an effective antiviral ointment from herpes zovirax.
Herpes on the skin of the face, lips, cheeks and eyes is a consequence of the impact on the body's tissue of certain viruses. Sometimes this disease can manifest itself in a person repeatedly for one year. Such rashes are accompanied by a strong itching, burning sensations and discomfort. Rales can develop not only on lips and mucous membranes, but also on the cheeks and near the mouth. In some cases, the diseases as a result of actively developing herpes bubbles can burst, thereby contributing to the further development of infection in the tissues of the skin. Thus, the skin is constantly infected with bacteria.
Nowadays, more than one hundred species of various herpes infections are known. The most common diseases are simple and hay herpes. These diseases have several stages with which it is necessary to fight the most efficient drugs. Today, doctors recommend using the treatments of the Zovirax in the treatment of various stages of herpes.
Moreover, this drug can be reliable protection and prophylactic measure from honesty infections into the human body. Especially herpes rashes can be disturbed in spring and autumn, when the immune system is significantly reduced. Treatment of grapes amazed by herpes must be accompanied by the use of the most effective drugs that doctors recommend today.
The drug Zovirax is used to treat herpes on lips and mucous membranes. Its active therapeutic substance is an acyclovir with high antiviral activity. Zovirax ointment includes acyclovir, thereby being a highly efficient drug with a pronounced antiviral action. This drug is able to cope with any kinds of herpes literally in a few days, as well as become excellent prevention against the penetration of infection into the human body.
The main function of the acyclovir is blocking the further reproduction of herpes viruses and the subsequent distribution of infections in damaged skin fabrics. The auxiliary substances in the composition of Ointment Zoviraks are propylene glycol and white vaseline. These substances perfectly soften the skin, gently and calmly affect the foci of inflammation.
Initially, this medical preparation was developed by scientists and doctors for use in ophthalmology. However, today the remedy is widely used to treat herpes. Zovirax Ointment is produced by the British pharmaceutical company "Glaksmitklein".
The main purpose of Mazi is the treatment of existing herpes symptoms on lips and mucous membranes, but this drug is also used to prevent the appearance of viral infection and its symptoms. In ophthalmology, Zovirax is used to treat herpes infection, which amazes the rogue of the cornea of \u200b\u200bthe eye. The eye ointment Zovirax is produced in tubes of 4.5 g. The remedy is a homogeneous consistency without lumps and grains. The drug has an oil structure, does not cause irritation and burning path.
The correct use of this drug describes in detail the instructions for the use of ointments from herpes zovirax.
- To combat unpleasant disease, it is necessary to evenly apply a small amount of ointment on the affected areas of lips or mucous membranes. Also, the drug is applied to the foci of skin rashes.
- Processing sick places is required 4-5 times a day. A break between procedures should be about four hours.
- Apply a medicinal ointment with clean fingers, carefully rubbing a small amount of drug with circular motions.
- The treatment with the means is important to carry out to the complete recovery and disappearance of herpes symptoms.
- It is not recommended to apply ointment on the mucous membranes of the oral cavity. Also should be avoided by chance in contact with the eye.
- Treatment by Zovirax can be started both in the early and late stages of the disease. Usually the course of treatment is 4-5 days.
Features of the drug
After entering the tissue, Zovirax penetrates directly into the cells affected by the virus. Upon local use, the drug destroys the virus on the surface surface and practically does not penetrate into systemic blood flow. Zovirax destroys not only the Herpes virus, but also chickenpox, Epstein-Barra virus and cytomegalovirus. The antiviral effect of ointments is due to therapeutic effects of acyclovir.
The drug has a systematic effect on pathogenic microorganisms. As a result of the action of the active component of the medicinal product, the virus enzymes pass several chemical reactions that destroy them. As a result, the interaction of acyclovir with pathogenic organisms is formed by the enzyme triffosphate acyclovir. It is he who actively interacts with the DNA polymerase - another enzyme that contributes to the synthesis of DNA of the virus itself. As a result of such chemical DNA reactions, the virus becomes not suitable for further reproduction, and the pathogenic microorganism itself stops functioning. As a result, viruses die, while not damaging healthy cells of the human body.
Zovirax affects only cells infected with viruses, so absolutely does not affect healthy and normal cells. This mechanism of the drug action is a significant advantage of ointments. The drug is non-toxic and absolutely safe for healthy cells of the human body.
The long-term use of medicinal ointments in the treatment of viruses is not recommended, since a long-term course of treatment may cause the stability of pathogenic microorganisms to acyclovir. With very long treatment, the drug loses its high effective therapeutic ability.
Indications
Zovirax is produced in the form of cream, ointment, tablets and injections. Each dosage form is intended for the treatment of various diseases and can be appointed to the patient only at the attending physician. For herpes lip and skin infection, the ointment of herpes on the lips of Zovirax is used. The eye ointment Zovirax is intended for the treatment of keratitis, which is caused by herpes viruses.
Main readings:
- viral herpes infections;
- chickenpox;
- prevention of herpetic infection;
- prevention and treatment of cytomegalovirus infection.
Contraindications
Contraindications to use are:
- pregnancy;
- lactation;
- individual intolerance to the components of the drug;
- allergic reaction to the drug;
- renal failure;
- neurological symptoms.
Zovirax ointment from herpes during pregnancy
The drug itself is non-toxic and safe. The absorption of the components of the drug in the bloodstream is very insignificant. However, clinical studies on pregnant women were not carried out, so it is impossible to argue with great confidence that the ointment Zovirax can be applied during pregnancy. Any drug can cause destructive consequences for the development of the fetus in the mother's womb. When appointing Zovirax, a pregnant woman needs to correlate the risks of the health of the future mother and the future child.
Eye ointment Zovirax can be used to treat even newborn children, but only by appointing a doctor and under strict medical control. For the treatment of herpes eye infection, newborn ointment is neatly applied under the lower eyelid.
Like any drug, use in the treatment of zovirax may cause the manifestation of side effects.
Analogs
The modern pharmaceutical market offers a large selection of analogs of the drug Zovirax. The domestic pharmacy network today offers such similar drugs: 
- ointment acyclovir;
- ointment acyclovir-acry;
- herpferon ointment;
- Acylostad;
- Acigerpin;
- Herpferon;
- Gerpex.
All data drugs include an acyclovir active medicinal substance in their composition and have similar therapeutic effects. At the same time, some drugs can cost several cheaper in pharmacies than Zovirax ointment.
Mid prices
The price of ointments from Herpes Zovirax varies within different limits. The average cost of this drug is about 350 rubles. However, the price in each pharmacy item may differ significantly. The cost of the drug at the points of sale depends on the purchasing cost of the manufacturer, as well as the markup of the pharmacy itself.
Store the drug in a closed tube, you can three years at room temperature. Freeze this drug is impossible. The interactions of Zovirax with other drugs were not detected.
Benefits
It is clinically proven that the ointment Zovirax is capable of quickly and effectively cope with herpes infections and adversely affects pathogenic microorganisms. Using in the treatment of various types of herpes, the drug Zovirax can be completely cured from manifestations and symptoms of herpes on lips, eyes and mucous membranes. The drug is completely non-toxic and can be used in the treatment of newborn children.
When using this drug should be careful, however, even during the tooling of the child, many doctors are prescribed with the treatment of herpes zoviraks to the future Mama. Today, the number of future mothers, which are infected with herpes, has increased significantly, as the disease statistics shows.
Herpess infection can also be observed in young children. Zovirax allows you to quickly cope with the windmill and other varieties of herpes. This drug effectively and quickly eliminates itching, rash, burning and promotes the rapid recovery of the baby.
Zovirax is able for a very short time to eliminate herpes on lips and mucous membranes. Bubbles around lips, nose, genitals disappear literally through four days of treatment. However, you should pass a full course of treatment specified in the instructions for ointment Zovirax. Elder viral herpes infection can also be effectively cured by Zovirax. Before applying this medicinal product, mandatory consultation with the doctor, which will appoint the right course of treatment.
Disappearing and extincting animals
Military analysts told about the background of the liberation of Aleppo where this group could be sent
Tattoo Stalin Tattoo value with Stalin's portrait
The rampant life of the Empress Elizabeth Petrovna after Elizabeth Petrovna, the ruler became
Avitaminosis symptoms, lack of vitamins in the body How to determine which vitamin is not enough in the body