Almagel is an effective drug against gastrointestinal disorders. What is the difference between various types of Almagel Almagel Neo and instructions for use

  • The date: 13.08.2020

Trade name of the drug

AlmaGel ® neo

International non-payable or group name

Algeldrat + Magnesium Hydroxide + Siemeticone

Dosage form

Suspension

AOMAGEL ® Neo composition

5 ml (one dimensional spoon) suspension contains:
Active substances:
Algelfrart (aluminum hydroxide gel - in terms of aluminum hydroxide) 340 mg;
Magnesium hydroxide (magnesium hydroxide paste - in terms of magnesium hydroxide) 395 mg;
Siemeticone (Simeticon Emulsion - in terms of dimethicone) 36 mg;

hydrogen peroxide solution 30% 0.495 mg, sorbitol 474.60 mg, sodium saccharinate 1.13 mg, hytelectloose 5.65 mg, citric acid monohydrate monohydrate 5.65 mg, ethylpagidroxybenzoate 7.90 mg, propyl apoproxibenzoate 3.40 mg, propylene glycol 113, 00 mg, macrogol 4000 452.00 mg, aromatizer orange 2.26 mg, ethanol 96% 113.00 mg, purified water to 5 ml.
10 ml (1 bag) suspensions contain:
Active substances:
Algelfrart (aluminum hydroxide gel - in terms of aluminum hydroxide) 680 mg;
Magnesium hydroxide (magnesium hydroxide paste - in terms of magnesium hydroxide) 790 mg;
Siemeticone (Simeticon Emulsion - in terms of dimethicone) 72 mg;

hydrogen peroxide solution 30% 0.990 mg, sorbitol 949,20 mg, sodium saccharinate 2.26 mg, hytelectloose 11.30 mg, citric acid monohydrate 11.30 mg, ethylpaultsibenzoate 15.80 mg, Propyl apoproxibenzoate 6.80 mg, propylene glycol 226, 00 mg, macrogol 4000 904.00 mg, aroma of orange 4.52 mg, ethanol 96% 226.00 mg, purified water to 10 ml.

AOMAGEL ® Neo Description

White or almost white suspension, with an orange smell.

Pharmacotherapeutic group

Antacid facility + winder

ATX code

Pharmacological properties

Pharmacodynamics
The combined means, the action of which is due to its composition components. It has an antacid, adsorbing, enveloping, windy effect. Algelfrart (aluminum hydroxide) and magnesium hydroxide neutralize free hydrochloric acid in the stomach, reduce the acidity of the gastric juice, binds bile acids. The weighty effect of magnesium hydroxide balances the ability of the algeldrat to slow down the intestinal motor. Simethikon makes it difficult to form gas bubbles and contributes to their destruction. The gases released at the same time are absorbed by the intestinal walls and are derived from the body due to the peristaltic.
Pharmacokinetics
Simethikon due to physiological and chemical inertness is not absorbed into organs and tissues and after passing through the gastrointestinal tract (GTS) is removed unchanged. Absorption of aluminum and magnesium ions in the intestines - low. With normal kidney function, the concentration of aluminum and magnesium in the blood does not change. In patients with chronic renal failure, the level of aluminum and magnesium in the blood can increase to toxic values \u200b\u200bas a result of the violation of their elimination.

AOMAGEL ® Neo indications for use

Acute gastritis; chronic gastritis in the increased and normal secretory function of the stomach (in the aggravation phase); acute duodenitis, duodenogastral reflux; ulcerative disease of the stomach and duodenum (in the aggravation phase); symptomatic gastrogen ulcers of various origin; erosion of the mucous membrane of the upper departments of the gastrointestinal tract; gastroesophageal reflux, reflux-esophagitis; acute pancreatitis, aggravation of chronic pancreatitis; Gastralgia, heartburn (after excessive use of ethanol, nicotine, coffee, drug intake; incorrect diet, negatively affecting the functioning of the gastrointestinal tract); flatulence; Brodyl or putrefactive dyspepsia.

Contraindications

Hypersensitivity, chronic renal failure, pregnancy, Alzheimer's disease, hypophosphatemia, children's age up to 10 years, congenital fructose intolerance.
With caution - a period of lactation, liver disease, alcoholism, brain injury, brain disease, epilepsy, children's and adolescent age from 10 to 18 years.

AOMAGEL ® Neo Method of Application and Dose

Adults
Inside, 2 dimensional spoons or 1 package of suspension with an orange flavor 4 times a day 1 hour after meals and in the evening before bedtime. If necessary, a one-time dose can be increased to 4 dimensional spoons or 1 bag 4 times a day, but the maximum daily dose should not exceed 12 dimensional spoons (b packets).
Children older than 10 years
Dosage determines the attending physician - usually 1/2 dose for adults
The course of treatment is not more than 4 weeks. Before taking, the suspension must be mixed, shaking the bottle or thoroughly warm up bag. It is advisable to take AlmaGel ® neo without diluting with water and not drinking. No fluid intake is recommended for half an hour after receiving the drug.

Side effect

Allergic reactions, nausea, vomiting, change in taste sensations, constipation, diarrhea.

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The interval between the reception of Almaty ® Neo and other medicines should be 1-2 hours. With a long admission, a sufficient flow of phosphorus with food should be ensured. Due to the lack of data of the controlled clinical trials with nursing breasts, women AlmaGel ® neo should be taken only after consulting a doctor. One dimensional spoon (5 ml) of the drug contains 0.113 g of ethyl alcohol. One bag (10 ml) of the preparation contains 0.226 g of ethyl alcohol. As a result, there may be complications in patients with diseases of the liver and brain, in suffering from alcoholism and epilepsy, in pregnant women and children under 18. The daily dose of the drug (8 dimensional spoons or 4 bags) contains 0.904 g of ethyl alcohol, the maximum daily dose of suspension (12 dimensional spoons or b packets) contains 1.356 g of ethyl alcohol. One dimensional spoon (5 ml) of Almagel ® neo contains 0.475 g of sorbitol. One bag (10 ml) of the suspension contains 0.950 g of sorbitol. Sorbitol is contraindicated with congenital intolerance of fructose and can cause irritation of the stomach and diarrhea. Almatyel ® Neo does not have a negative impact on the ability to manage vehicles and work with mechanisms requiring increased concentration and speed of psychomotor reactions.

Form release

Suspension for intake.
170 ml or 200 ml of the drug in a glass bottle. Each bottle along with the instructions for use and a dimensional spoon on 5 ml in a cardboard pack.
170 ml or 200 ml of drug in a polyethylene terephthalate bottle. Each bottle along with the instructions for use and a dimensional spoon on 5 ml in a cardboard pack.
10 ml of the drug in a sachet of multilayer foil. 10 or 20 bags along with instructions for use in a cardboard pack.

Storage conditions

In the place protected from light at a temperature not higher than 25 ° C. Do not freeze!
Keep out of the reach of children!

active substances:5 ml (1 dimensional spoon) suspensions contain:

aluminum hydroxide gel in terms of aluminum hydroxide 340 mg,

magnesium hydroxide paste in terms of magnesium hydroxide 395 mg,

emulsions of Siemetikon 30% in terms of polydimethylsiloxane 36 mg;

10 ml (1 bag) suspensions contain:

aluminum hydroxide gel in terms of aluminum hydroxide 680 mg,

magnesium hydroxide paste in terms of magnesium hydroxide 790 mg,

emulsions of Siemetikon 30% in terms of polydimethylsiloxane 72 mg;

excipients: hydrogen peroxide solution (30%), sorbitol (E 420), saccharine sodium, hydroxietylcelide, lemon monohydrate acid, ETYLAPAHIDROCYBENZOAT (E 214), propyl apopilroxybenzoate (E 216), propylene glycol, macrogol 400, firing orange, ethanol 96%, purified water .

Dosage form

Suspension for oral administration.

White or almost white suspension with orange smell.

Title and location of the manufacturer

Balkanafarma Trojan Hell / Balkanpharma-Troyan AD.

Bulgaria, 5600 Troyan, Vul. Creashna, 1/1, Krayrechna Str., 5600 Trojan, Bulgaria.

Pharmacotherapeutic group

Antacids. Combinations of simple salts and windy (antiflature). PBX code A02A F02.

Almatyel ® Neo-balanced aluminum gel of hydroxide and magnesium hydroxide in combination with the whirlpool component - symmetone. It has a long antacid effect, has a soft laxative effect, successfully eliminates constipation and reduces meteorism in patients with a stomach ulcer.

The double mechanism of its action, combining acid-neutralizing ability and cytoprotective activity, ensures the protection of the stomach mucosa and its healing during damage.

Alkaline active components of the drug are finely dispersed, due to which their active surface increases, a closer contact with the surface of the gastric mucosa and duodenum is ensured, the evacuation of the contents of the stomach is slowed down and the neutralizing action is extended.

The cytoprotectant activity is associated with the activation of the synthesis of prostaglandins, which stimulate the secretion of mucus and bicarbonates of the stomach mucosa.

Considering the ability of the drug to bind bile acids and lysolecin, as well as to give a gastroprotective action, AlmaGel ® neo can be used to treat duodenogastral reflux.

Siemeticone, which is part of the drug, contributes to the elimination of meteorism.

Siemeticone is a stable silicone substance that is not absorbed from the digestive channel, causes the natural release of gases and their absorption by the intestinal walls.

Simethikon has its effect in the lumen of the subtle intestines and is excreted from the body unchanged.

The constituents of the drug are not absorbed in the gastrointestinal tract and thus do not lead to clinically significant plasma concentrations when applying in recommended doses and at the recommended duration of treatment.

Aluminum hydroxide neutralizes the increased secretion of hydrochloric acid in the stomach, forming aluminum chloride. Under the influence of an alkaline intestinal medium, the latter turns into alkaline salts of aluminum, which are completely absorbed and outlined with the feces. With normal kidney function, the serum level of aluminum is practically not changed.

Magnesium hydroxide also neutralizes hydrochloric acid in the stomach and turns into magnesium chloride. In the intestine, it turns into magnesium carbonate, which is poorly absorbed, therefore, the concentration of magnesium ions in the blood is practically not changed.

In patients with chronic renal failure, the level of aluminum and magnesium ions can increase to toxic values \u200b\u200bdue to violations of their elimination.

Indications for application

Symptomatic treatment of diseases of the digestive tract, which are accompanied by an increased or normal acidity of gastric juice and increased gas formation.

The drug is applied independently or in combination with other drugs at:

  • gastritis and duodenitis;
  • stomach and duodenal ulcer;
  • erosions of the stomach and duodenum;
  • gastro-infahalnia reflux disease;
  • duodenogastral reflux;
  • functional dyspepsia;
  • meteorism, discomfort as a result of increased gas formation.

Contraindications

Hypersensitivity to any existing and / or auxiliary substances that are part of the drug. Heavy impairment of kidney function, including in patients in hemodialysis, in which there is a risk of increasing the concentration of aluminum and magnesium ions in serum to toxic levels as a result of a decrease in the removal through the kidneys. Hypophosphamia, heavy osteoporosis, Alzheimer's disease, habitual constipation, chronic diarrhea, intestinal obstruction, suspicion of appendicitis, bleeding from the digestive path of unclear origin, severe pain in the stomach of unspecified genesis, ulcerative colitis, states that cause impaired water and electrolyte balance.

Proper security measures when applying

Before the use of the drug, the presence of a malignant process should be deleted.

Aluminum hydroxide can lead to a constation, and magnesium hydroxide can cause intestinal hypocineesia. The use of this product in high doses may cause or complicate intestinal obstruction and intestinal obstruction, especially in patients with increased risk of such complications, for example in patients with renal failure or in elderly patients.

Patients need to consult a doctor in case:

  • reduction of body weight;
  • the emergence of difficulties in swallowing or constant sensation of discomfort in the stomach;
  • digestive disorders that appeared for the first time or change the flow of existing digestive disorders;
  • renal failure.

In patients with impaired kidney function, it is possible to increase the plasma levels of aluminum and / or magnesium, so it should be borne in mind that the long-term use of high doses of the drug can lead to the development of dementia and microcolitan anemia.

With prolonged use of the drug, it is necessary to admire a sufficient amount of phosphorus to the body, since aluminum hydroxide is associated with phosphates and reduces their absorption from the digestive channel. The removal of calcium with urine increases, which can lead to disorders of calcium-phosphate equilibrium and create conditions for the development of osteomalysis (symptoms - complaints of weakness and pain in the bones).

During the treatment of patients with renal failure, it is necessary to control the renal status indicators, the size of the ulcers, the appearance of diarrhea, the serum level of aluminum and magnesium.

Each dose (10 ml) of the drug comprises:

  • 0.226 g of ethanol, the presence of which can negatively affect the condition of patients with diseases of the liver and brain, in persons with alcohol addiction, epilepsy, in pregnant women and in children under the age of 14;
  • 0.95 g of sorbitol, which is contraindicated to patients with rare hereditary diseases, such as fructose intolerance.

Parabentes, which are part of the drug as auxiliary substances, can cause allergic reactions, including urticaria, bronchospasm.

Application during pregnancy or breastfeeding

Due to the lack of data of adequate clinical studies, women during pregnancy AlmaGel ® neo can only be applied to the appointment of a doctor if the expected benefit for the mother exceeds the possible risk to the fetus / child.

The content of aluminum and magnesium ions, capable of influencing the transit in the gastrointestinal tract, namely:

  • magnesium salts of hydroxide can cause diarrhea;
  • aluminum salts may cause constipation and worsen the streams of constipation, often

observed during pregnancy,

therefore, long-term use and excess of the doses of this drug should be avoided.

With the use of Almagel ® Neo pregnant women, the drug may harm due to the content of ethyl alcohol (0.226 g in one dose).

During treatment, the drug should stop breastfeeding.

Ability to influence the reaction rate when managing vehicles or working with other mechanisms

There is no data regarding negative impact on the ability to manage vehicles or work with complex mechanisms.

Children

Apply children aged 14 years.

The safety and effectiveness of the use of the drug for children under 14 is not installed.

Method of application and dose

Adults and children over 14 years old:

With a gastalafagal reflux disease, the recommended dose is 10-15 ml (2-3 dimensional spoons) or 1 bag 4 times a day after 1 hour after meals and before bedtime. After achieving the desired effect, the recommended dose is 10 ml (2 dimensional spoons) or 1 bag 4 times a day.

With gastritis, duodenitis, stomach erosions and duodenum, ulcerative disease of the stomach and duodenum, duodenogastral reflux, functional dyspepsia, meteorism The recommended dose is 10 ml (2 dimensional spoons) or 1 package 4 times a day after 1 hour after meals and before Snow.

The duration of treatment is determined by the doctor.

Maximum daily dose - 60 ml (12 dimensional spoons or 6 bags), the maximum treatment duration is 4 weeks.

If symptoms do not disappear, you should consult a doctor.

The drug must be taken in an undersedized form. It is not recommended to use liquids within 30 minutes after its reception. Before use, the suspension must be thoroughly homogenized, shaking the bottle.

Patients with impaired kidney function. The drug should be taken after consulting a doctor. With long-term use, the condition of the kidney function should be taken into account.

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The long-term use of Almagel ® neo can cause hypermagnium, despite the fact that the drug is almost not absorbed from the digestive channel. Overdose symptoms are manifested by fast fatigue, redness of the face, exhaustion, muscle weakness and inadequate behavior.

Signs of metabolic alkalosis can also be observed: change in mood or mental activity, numbness or muscle pain, nervousness and fast fatigue, breathing slowing, unpleasant taste.

In suspected overdose of the drug or when clinical signs, it is necessary to cancel the drug and take measures to quickly eliminate the drug from the gastrointestinal tract (introduce activated carbon, make the stomach and other procedures to reduce the absorption of aluminum and magnesium ions).

Treatment with magnesium overdose: rehydration, forced diuresis. You can assign calcium gluconate intravenously. In the case of renal failure, hemodialysis is needed or peritoneal dialysis.

Side effects

Long-term use of Almagel ® neo or taking high doses can cause phosphor deficiency syndrome (loss of appetite, muscle weakness, a decrease in body weight).

It should be borne in mind that even when applying conventional doses of the drug in patients, the diet of which is characterized by a low phosphorus content, it is possible to reduce the phosphorus content in the body, enhancing the processes of resorption in bone tissue, hypercalciuria, osteomalacia, osteoporosis, since this drug contains aluminum (see. Section "Appropriate security measures when applied). In patients with renal insufficiency, elevated plasma concentrations of both aluminum and magnesium are observed, therefore the long-term use of high doses of aluminum and magnesium salts can lead to the development of encephalopathy, dementia, microcitar anemia, or worsening the dialis induced during osteomalysis.

Aluminum hydroxide can be dangerous for patients with porphyria that get hemodialysis.

Adverse Reactions:

  • ;from the gastrointestinal tract: Violation of taste (sensation of the taste of chalk), diarrhea, constipation, nausea, vomiting, change in the color of the wheel masses;
  • ;from the immune system: The reactions of hypersensitivity, including bronchospasm, itching, urticaria, angioedema edema and anaphylactic reactions.

In case of identifying any unwanted impacts or unusual reactions, advise you with a doctor regarding the further use of the drug!

Interaction with other medicines and other types of interactions

AlmaGel ® neo interacts with some other drugs that are used orally. There is a decrease in the absorption of drugs that are accepted simultaneously with the gastrointestinal tract. As a measure between antacids and other drugs, take a break.

It is recommended to take 2 hours before or 2 hours after Applications of the drug AlmaGel ® neo: Tetracycline antibiotics (tetracycline, doxycycline), fluoroquinolones (ciprofloxacin, norfloxacin, offloxacin), H 2 -anthogistamine, anti-tuberculosis drugs: etchutol, isoniazide (oral), atenolol, metoprolol, propranolol, chlorookhin, cyclini, Diglowisale, Digoxin, Diffosphonates, Fexofenenadine, iron (salt), sodium fluoride, glucocorticoid preparations (described interaction with prednisone and dexamethasone), indomethacin, kayekshalate, ketoconazole, Lanzoprazole, lincoosamida, phenothiazine neuroleptics, penicillamine, phosphorus (additives), thyroxine.

Combinations to consider: With simultaneous use with salicylates, the excrepaniation of sabicilants by the kidneys is enhanced due to urine och.

The drug does not apply simultaneously with chinolines.

An derivation of chinidine with manifestations of quinidine toxicity may be disturbed, especially in patients with renal failure.

Simultaneous use with cholinergic means reduces their effectiveness.

The simultaneous use of aluminum hydroxide and citrates can lead to an increase in aluminum level, especially in patients with renal failure.

The use of the drug together with drugs that have a cisherous shell can lead to a more rapid dissolution of the shell and irritation of the stomach and duodenum.

The drug may reduce the absorption of folic acid.

With a combined application with Levothyroxin, it is possible to reduce its action hormonal. Pyrenspine enhances and prolongs the action of Almagel ® Neo.

Shelf life

Storage conditions

In the original packaging at a temperature not higher than 25 ° C. Keep out of the reach of children. Do not freeze!

After the first disclosure of the primary packaging, the suspension can be stored within 30 days under the specified conditions.

Packaging

170 ml or 200 ml in a bottle along with a measured spoon.

10 ml in foil bags. 10 or 20 bags in a cardboard pack along with instructions for use.

Almagel Neo - drug antacid, adsorbing, wind and enveloping action.

Release form and composition

The drug is manufactured in the form of a suspension for intake, which is a white or almost white homogeneous liquid with an orange smell (170 ml or 200 ml in dark glass or polyethylene terephthalate vials with an injected plastic cover, in a cardboard pack One bottle, a measuring spoon on 5 ml and Medical instructions for the drug; 10 ml in bags of multilayer foil, in a cardboard pack of 10 or 20 bags and instructions for the use of Almagel NEO).

Composition on 5/10 ml of suspension (one dimensional spoon / one bag):

  • active components: magnesium hydroxide (in the form of magnesium hydroxide paste) - 395/790 mg, algelfrart (in the form of aluminum gel hydroxide) - 340/680 mg, symmetics (as a symulsification of Simeticon) - 36/72 mg;
  • auxiliary components: sorbitol, lemonic acid monohydrate, propyl aprichedroxybenzoate, hydrogen peroxide solution 30%, macrogol 4000, ethanol 96%, sodium saccharinate, propylene glycol, ethylpagidroxybenzoate, hyethyllose, flavoring orange, purified water.

Pharmacological properties

Pharmacodynamics

Almagel Neo is a combined drug with enveloping, antacid, wind turbulent and adsorbing effect.

Magnesium hydroxide and aluminum hydroxide (algelfalg) bind bile acids, neutralize free hydrochloric acid and reduce the acidity of gastric juice. Due to the relaxing properties of the magnesium hydroxide, the deceleration of the intestinal motility caused by algelfrel is equalized.

Siemeticone prevents the formation of gas bubbles and contributes to the destruction of the released gas bubbles. Gases that are formed at the same time are absorbed in the intestinal walls and due to the peristaltics are derived from the body.

Pharmacokinetics

The absorption of magnesium and aluminum ions in the intestines is insignificant. In patients with normal kidney function, the plasma concentration of magnesium and aluminum does not change. In chronic renal failure, it is possible to increase the level of magnesium and aluminum in the blood to toxic concentrations, since the deduction of the data of the ions is broken.

Siemeticone is chemically and physiologically inert, so it is not absorbed into the tissues and organs, and after passing through the digestive tract, it is displayed in its original form.

Indications for use

  • aggravation of peptic ulcer and stomach diseases;
  • inflammation of the 12-rosewood in the acute phase;
  • duodenogastral reflux (casting the contents of a 12-rosewoman in the stomach);
  • exacerbation of chronic gastritis with a normal or elevated secretory intestinal function;
  • acute gastritis;
  • reflux Ezophagitis and Gastroesophageal Reflux;
  • heartburn and gastralgia (due to excessive use of coffee, ethanol or nicotine, as well as the reception of various drugs; due to an incorrect diet, negatively affecting the functioning of the gastrointestinal tract);
  • symptomatic ulcers of the gastrointestinal tract of various etiologies;
  • exacerbation of chronic pancreatitis or acute pancreatitis;
  • erosion of the mucous membranes of the upper departments of the gastrointestinal tract;
  • meteorism (excess accumulation of gases in the intestines);
  • sniffle or fermentation dyspepsia.

Contraindications

Absolute:

  • low blood phosphate (hypophosphatemia);
  • chronic renal failure;
  • hereditary fructose intolerance;
  • alzheimer's seeding dementia (Alzheimer's disease);
  • pregnancy period;
  • children's age under 10 years old;
  • increased individual sensitivity to the main or auxiliary components of the suspension.

Relative (Almagel Neo apply with caution):

  • liver diseases;
  • card and brain injuries;
  • epilepsy;
  • brain diseases;
  • excessive use of alcohol;
  • breastfeeding period;
  • patient age from 10 to 18 years.

Almagel Neo: Instructions for use (dosage and method)

Suspension of Almagel Neo is taken inward, without diluting with water and if possible, without drinking. Within 30 minutes after taking the drug, it is not recommended to use liquid. Before use, you need to shake the bottle or packet to homogenize the suspension.

Adults Almaty Neo are prescribed 10 ml (1 bag or 2 dimensional spoons) four times a day. The drug should be taken one hour after meals and in the evening (in front of the night bed). If necessary, an increase in one-time dose is possible to 15 ml. The maximum dose of the suspension is 60 ml (12 dimensional spoons) per day.

Children and adolescents over the age of 10, AlmaGel Neo assigns the attending physician. Typically, the daily dose of the drug for children is ½ daily dose for adults.

The duration of therapy is not more than 4 weeks.

Side effects

During the treatment of Albell, the patient may have nausea, a change in taste, vomiting, diarrhea or constipation, as well as allergic reactions.

In the case of long-term intake of the drug in large doses, the following side effects are observed: hypermagniasmia, hypocalcemia, hyperauluminia, hypophosphatemia, hypercalciuria, osteoporosis, nephocalcinosis, osteomation, renal impairment, encephalopathy.

In patients with renal failure, it is possible to appear thirst, reduction of blood pressure and a decrease in reflexes (hypox).

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With prolonged therapy with high doses of Almagle Neo, hypermagniamia may occur, which is characterized by redness of the face, muscle weakness, fast fatigue, depletion and inadequacy of behavior.

The appearance of symptoms of metabolic alkalosis: breathing slowdown, muscle pain, or their numbness, unpleasant taste sensations in the mouth, violation of mental activity, nervousness, mood change, fast fatigue.

Under the overdose of Almagel, neo it is necessary to urgently take measures to eliminate its residues from the body (stimulation of the reflex, washing the stomach, oral use of activated carbon).

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The Suspension of Almagel Neo should be taken separately from other drugs (with an interval of at least 1-2 hours).

If the treatment with the drug is long, it is necessary to provide additional flow of phosphates with food.

In one dimensional spoon (5 ml) of the suspension contains 0.113 g of ethanol, and in one bag (10 ml) - 0.226, the amount of ethanol in the usual daily dose of Almatily neo (4 bags or 8 dimensional spoons) - 0.904 g, in the maximum daily dose (6 bags or 12 measuring spoons) - 1.356. Due to the content of ethyl alcohol in the composition of it with caution, it should be used in patients with epilepsy and alcoholism, patients with diseases of the brain and liver, children and adolescents under 18.

In one dimensional spoon (5 ml) of the suspension, the sorbitol content is 0.475 g, and in one bag (10 ml) - 0.95 sorbital cannot be taken to patients with congenital intolerance to fructose; It can cause diarrhea and stomach irritation.

Impact on the ability to control vehicles and complex mechanisms

Almatil Neo does not have any negative impact on the patient's ability to engage in work related to increased concentration of attention and demanding a rapid response (automobile management, dispatching and operator activities, etc.).

Application during pregnancy and lactation

Almaglel Neo is contraindicated to pregnant women.

During the lactation period, the drug can be applied only to the prescription of the doctor, since the controlled clinical tests of the means to use it in this period were not carried out.

Childcare

In children under 10 years old, AlmaGel does not apply.

In a children's and adolescence of 10 to 18 years, treatment with caution is carried out.

With violations of the kidney function

The drug cannot be applied in chronic renal failure.

Patients with impaired renal function Almagel Neo are prescribed with caution.

When violations of the liver function

Patients with violation of the liver function Almagel Neo are prescribed with caution.

Application in old age

Sorry of Elderly Almaty Neo is prescribed only under the control of the doctor.

Medicinal interaction

Almagel neo slows down and reduces the absorption of many drugs: salicylates, Blocators H 2 -Histamine receptors, quinolones, tetracycline antibiotics, indirect anticoagulants, beta-adrenobloclockers, barbiturates, digoxin, chlorpromazine, dyphlunisale, isoniazide, azithromycin, pivampicillin, fexophenadin, zerzitabina, Penicilline, indomethacin, phenytoin, itraconazole, ketoconazole, cefpodoxy, rifampicin, dipyridamole, lansoprazole, epsodeoxychole and minoroxicole acids.

With simultaneous use with M-cholinoblockers that slow down the gastric emptying, the therapeutic effect of Almagel Neo is strengthened.

Analogs

Aliamnel NEO analogues are Almagl, Almaty A, Renny, Vicair, Simalgel-VM, and others.

Terms and conditions of storage

Store in a darkened place at a temperature of not more than 25 ° C. Suspension can not be frozen. Take care of children.

Shelf life - 2 years.

AlmaGel - This is an effective remedy that has an antacid therapeutic effect. Its action is aimed at relieving gastritis symptoms, ulcerative disease, esophagitis. Also Almagel effectively eliminates the painful sensations in the area of \u200b\u200bthe stomach and heartburn. The drug has an anesthetic effect, so it is actively accepted to eliminate pronounced pain in various digestive system diseases.

Types and form of release

Almagel with gastritis is released in two forms: suspension and tablets. The suspension contains various components, thanks to which the drug acquires additional properties. The pharmacy can find the following types of suspension:

  • Almagel suspension (contains only the main components of aluminum and magnesium hydroxide gel);
  • Suspension of Almagel A (except for the main components there is an anesthetic benzocaine);
  • Suspension of Almagel Neo (except the main components there is a simethicone, which is struggling with increased gas formation);

Each of the proposed options is released in a package of a certain color, so that they are easily distinguished from each other. When buying tablets, pay attention to the packaging. There should be a letter t, which determines the dosage form. Almagel Neo is released in a red box. Simple Almatiel is produced in green packaging, and Almagl A - in yellow.

Composition of Almaty

Regardless of the form of the drug, in its composition there are both basic and auxiliary components, thereby achieving the necessary consistency in the form of a suspension. Each form drug has its own set of components:

  • AlmaGel green - algelfrart (aluminum hydroxide gel), magnesium hydroxide paste;
  • Almagel A yellow - algelfrart (aluminum hydroxide gel), magnesium hydroxide paste, benzocaine;
  • Almagel Neo-algelfrel (aluminum hydroxide gel), magnesium hydroxide paste, symmetics;
  • Almagel T - tablet contains 500 mg of magaldrat (magnesium and aluminum hydroxide).

Since additional components in tablets and suspensions are different, then refer to the following table:

Almagel Green and Almaty and Yellow Almaty Neo Tablets AlmaGel
Sorbitol Sorbitol mannitol
Hydroxyethylcellulose hydrogen peroxide 30% (perhydrol) microcrystalline cellulose
Methylpagidroxybenzoate sakharinat sodium sorbitol
propilepagidroxybenzoat Gileteloza magnesium stearate
Butyl aphahydroxybenzoate citric acid monohydrate
sakharin sodium ethylpagidroxybenzoate
lemon oil propilepagidroxybenzoat
Ethanol propylene glycol
distilled water makroogol 4000.
orange flavoring
ethyl alcohol 96%
distilled water

Indications

Before accepting the drug, you need to get acquainted with his testimony:

  • ulcer of the stomach and duodenal intestine during the exacerbation period;
  • gastritis with normal and increased acidity of acute or chronic type during the exacerbation period;
  • duodenitis;
  • enteritis;
  • hernia of the esophageal hole of the diaphragm;
  • reflux-esophagitis;
  • functional intestinal disorders;
  • colitis;
  • discomfort and pain syndrome in epigastrics in non-compliance with diet, after drinking coffee, nicotine, alcohol;
  • gastralgy, heartburn;
  • increased gas formation;
  • brodyl or putrefactive dyspepsia.

Reception scheme


Instructions for the use of Almaty implies its internally consumption. On the recommendation of the doctor, it is necessary to consume 1-3 teaspoons 3 times a day. If there is an ulcer, the drug is taken between meals. If the therapeutic effect is achieved, reduce Almaty dosage to 1 teaspoon 3 times a day. The general course will be 2-3 months.

In preventive purposes, the drug should use 1-2 spoons. Children AlmaGel give strictly on the recommendation of the doctor. If a child is up to 10 years old, then 1/3 doses of adults, and from 10 to 15 years old - ½ dose of adults.

If there is a disease, accompanied by nausea, vomiting, painful sensations in the abdomen, then a course of therapy to start with Almaty A. If the symptoms were fed, then go to ordinary Almagel.

In addition to the reception of Almagel and other effective drugs, success in the treatment of gastritis is impossible without a diet. To learn more about the useful products and the basic rules of the gastritis diet, you need to get acquainted with the following video:

Side effect


When administering Almaty, the Paisent may have the following side effects:

  • changing taste sensations;
  • nausea, vomiting;
  • diarrhea;
  • spasm of the stomach;
  • pain in the epigastric region;
  • constipation;
  • drowsiness.

Contraindications

It is impossible to take Almagel in the following cases:

  • increased sensitivity to the drug components;
  • pronounced disorder of the kidneys;
  • alzheimer's disease;
  • children up to 1 month.

Application during pregnancy and lactation

Almagel during pregnancy can be taken, but not only for 3 days. But during the acting from this drug it is necessary to refuse.

Medicinal interaction

If simultaneously taking Almagel with other drugs, then you can reduce the therapeutic effect of tetracycline antibiotic antibiotics, histamine-receptor blockers, glycosides of dimensions, iron salts, ciprofloxacin, phenothiazines, isoniazide, beta-adrenobloclaims, indomethacin and ketoconazole.

This article allows you to familiarize yourself with the instructions for the use of the drug. Almagel. There are reviews of site visitors - consumers of this medicine, as well as the opinions of medical professionals for the use of Almagel in their practice. A big request to more actively add your reviews about the preparation: helped or did not help the medicine to get rid of the disease, which complications were observed and side effects, possibly not stated by the manufacturer in annotations. Analogs of Almagel in the presence of available structural analogues. Use for the treatment of heartburn and other symptoms with ulcers, gastritis in adults, children, as well as during pregnancy and breastfeeding. Composition of the drug.

Almagel - Neutralizes free hydrochloric acid in the stomach, which leads to a decrease in the digestive activity of the gastric juice. Does not cause secondary hypersecretion of gastric juice. It has an adsorbing and enveloping effect, reduces the effect of damaging factors on the mucous membrane.

The therapeutic effect after taking the drug occurs after 3-5 minutes and continues on average 70 minutes.

Almagel provides long-term local neutralization of a continuously separated gastric juice and reduces the content of hydrochloric acid in it to optimal boundaries. Aluminum Hydroxide suppresses the secretion of pepsin, neutralizes hydrochloric acid, forming aluminum chloride, which in an alkaline intestinal environment turns into alkaline salts of aluminum. Magnesium hydroxide also neutralizes hydrochloric acid, turning into magnesium chloride. Thus, countering the effect of aluminum hydroxide causing constipation. Magnesium hydroxide and magnesium chloride is resistive to a slight degree and practically do not affect the concentration of magnesium ions in the blood. The composition of the preparation sorbitol contributes to the enhanced selection of bile and exhibits a light laxative effect, complementing the effect of magnesium hydroxide.

Almagel does not sharply increase the pH of the contents of the stomach, buffers its value from 4.0-4.5 to 3.5-3.8 (physiological value) in the period between receptions. The drug forms a protective layer, providing a uniform distribution on the gastric mucosa of the stomach of active substances and has a long local action without the subsequent formation of carbon dioxide in the stomach, which, in turn, is the cause of meteorism, feelings in the epigastrine region and secondary strengthening of the secretion of hydrochloric acid.

The drug during oral administration refers to weakly toxic means and does not have embryotoxic, teratogenic and mutagenic effects. In some cases, elevated tendon reflexes in newborns, whose mothers took the drug for a long time. In addition, newborn has the danger of hypermagniasia development, especially with a state of dehydration, therefore, the prolonged use of the drug is not recommended pregnant and newborns.

Benzocaine (included in the drug Almagel A) has an effective and long-lasting local painful effect with pronounced pain syndrome.

Siemeticone (included in the drug Almagel neo) makes it difficult for the formation of gas bubbles and contributes to their destruction. The gases released at the same time are absorbed by the intestinal walls and are derived from the body due to the peristaltic.

Composition

Algelfrart (aluminum Hydroxide gel) + magnesium hydroxide paste + excipients (almagel in green packaging).

Algelfrart (aluminum hydroxide gel) + magnesium hydroxide paste + benzocaine + auxiliary substances (almagel A in yellow packaging).

Algeldrat (aluminum hydroxide) + magnesium hydroxide + sytlecone + excipients (Almagel neo).

Pharmacokinetics

Almagel is an unsyaped drug. In compliance with the correct dosing regime and the duration of treatment, it is practically not resistive to the gastrointestinal tract and has a long uniform effect, without disturbing the electrolyte balance and does not create the risk of alkalosis or other metabolic disorders. It does not irritate the urinary system and during long-term use does not cause alkalosis and the formation of accretions in the urinary tract.

Indications

  • ulcerative ulcer of the stomach and duodenal intestine in the aggravation phase;
  • acute gastritis and chronic gastritis with elevated and normal secretory function in the aggravation phase;
  • duodenitis;
  • enteritis;
  • hernia of the esophageal hole of the diaphragm;
  • reflux-esophagitis;
  • functional intestinal disorders;
  • colitis;
  • discomfort and pain in the epigastrics in the error in the diet, after drinking coffee, nicotine, alcohol;
  • gastralgia, heartburn (after excessive use of ethanol (alcohol), nicotine, coffee, drug intake; incorrect diet, negatively affecting the operation of the gastrointestinal tract);
  • flatulence;
  • brodyl or putrefactive dyspepsia.

Forms of release

Suspension for intake.

Other forms, be something syrup or pills, does not exist.

Instructions for use and reception scheme

AlmaGel

The drug is taken inward. Before each admission, the suspension must be thoroughly homogenized, shaking the bottle.

Treatment

The drug is taken 45-60 minutes after meals and in the evening before bedtime.

Adults and children over 15 years old are prescribed 5-10 ml (1-2 dimensional spoons) 3-4 times a day. If necessary, a one-speed dose can be increased to 15 ml (3 dimensional spoons). Children aged 10 to 15 years are prescribed in a dose equal to half a dose for adults.

After reaching the therapeutic effect, the daose dose is reduced to 5 ml (1 dimensional spoon) 3-4 times a day for 15-20 days.

Prevention

5-15 ml 15 minutes before receiving medicines with an irritant action.

Almagel A.

Inside. For the purpose of the doctor, 1-3 dosage (tea) spoons, depending on the acuteness of the case, 3-4 times a day half an hour before meals and in the evening before bedtime.

In children, the drug is applied strictly to the appointment of a doctor: children under 10 years old are prescribed 1/3 doses for adults, and for children from 10 to 15 years old - 1/2 doses for adults.

In case of diseases, accompanied by nausea, vomiting and abdominal pain, treatment starts with Almaty A, and on the disappearance of the listed symptoms go to the reception of Almaty.

Almagel neo

Adults

Inside, 2 dimensional spoons of suspension with an orange taste 4 times a day after 1 hour after meals and in the evening before bedtime. If necessary, a one-time dose can be increased to 4 dimensional spoons, but the maximum daily dose should not exceed 12 dimensional spoons.

Children older than 10 years

The dosage determines the attending physician - usually 1/2 dose for adults.

The course of treatment is not more than 4 weeks. Before taking a suspension, it is necessary to homogenize, shaking the bottle. It is advisable to take Almagel Neo in an undeveloped form. No fluid intake is recommended for half an hour after receiving the drug.

Side effect

  • changing taste sensations;
  • nausea, vomiting;
  • spasm of the stomach;
  • pain in the epigastric region;
  • constipation;
  • drowsiness.

Contraindications

  • increased sensitivity to the components of the drug;
  • pronounced violation of the kidney function;
  • alzheimer's disease;
  • early children's age (up to 1 month), up to 10 years (for Almagel Neo).

Application in pregnancy and breastfeeding

Avoid appointment with nursing mothers.

Application in children

Contraindication: Early children's age (up to 1 month) and up to 10 years old Almagel Neo.

In older children, the drug is applied strictly to the appointment of a doctor: for children up to 10 years old are prescribed 1/3 doses for adults, and children from 10 to 15 years old - 1/2 doses for adults.

special instructions

The interval between the method of almagel and other medicines should be 1-2 hours.

Long-term treatment with high doses of drug and poor food phosphorus can lead to predisposed patients to the development of phosphorus deficiency in the body, increased resorption and excretion of calcium with urine and the emergence of osteomalysis. Therefore, with long-term reception of the drug, it is necessary to ensure sufficient admission to the food of phosphorus. In patients with chronic kidney failure, except for osteomalysis, edema extremities, dementia and hypermagnias may be observed.

Before taking the bottle should be shaking.

Medicinal interaction

With the simultaneous use of the almagel, it can reduce the therapeutic effect of tetracycline antibiotic antibiotics, histamine H2 receptor blockers, glycosides of anticipate, salts of iron, ciprofloxacin, phenothiazines, isoniazide, beta-adrenoblastors, indomethacin and ketoconazole.

Analogs of the drug Almagel

Structural analogues for the acting substance:

  • Agifluix;
  • Almol;
  • Alumag;
  • Almagel A;
  • Almagel Neo;
  • Anazid Forte;
  • Gastracide;
  • Maaloks;
  • Maaloks mini;
  • Rivolox.

Analogs in the pharmacological group (antacids):

  • Calcium Addiction;
  • Actal;
  • Alfogel;
  • AluGustrin;
  • Anazid Forte;
  • Antarite;
  • Bekarbon;
  • Hastal;
  • Gasterin;
  • Gastric;
  • Gastoromazole;
  • Gevisson;
  • Gevisson Forte;
  • Gelusil;
  • Gelusil varnish;
  • Gevently;
  • Estate;
  • Dajin;
  • Calcium carbonate;
  • Magalfil 800;
  • Magnatol;
  • Magistrad;
  • Magnesium oxide;
  • Milk of Magnesia;
  • Sodium bicarbonate;
  • Sodium bicarbonate;
  • Realzer;
  • Renny;
  • Riofast;
  • ROCHEL;
  • Rutacid;
  • Symalgel VM;
  • Schiralate;
  • Talcid;
  • Tamm;
  • Tannakompa;
  • Tisacid;
  • Topalkan;
  • Phosphhalugel;
  • Andrews Antacid.

In the absence of analogues of drugs on the active substance, you can follow the links below on the disease, which helps the appropriate drug, and see the analogues on therapeutic effects.