Maalox composition instructions for use. Maalox - there are contraindications and you need to know about them

  • Date: 04.11.2019

Excipients: hydrochloric acid 10%, citric acid monohydrate (EZZO), peppermint oil, mannitol (E421), methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate (E216), sodium saccharinate (E954), sorbitol 70% (E420), hydrogen peroxide 30%, purified water.

Description

A creamy liquid that resembles milk in appearance and has a sweet mint flavor and scent.

Pharmacotherapeutic group

Antacid. CodeATX: A02AD01.

Pharmacodynamics

The drug neutralizes free hydrochloric acid, which leads to a decrease in the peptic activity of gastric juice. Does not cause secondary hypersecretion. It also has an absorbent and enveloping effect, reducing the effect of damaging factors on the mucous membrane.

It is passable for x-rays.

The total antacid capacity (titration at pH = 1) is 44.9 mmol H + (in vitro in the study of a single dose according to the Walter method).

Pharmacokinetics

Magnesium and aluminum hydroxides are considered topical antacids, which are practically not absorbed from the gastrointestinal tract when taken in recommended doses and, accordingly, do not have general effects on the body.

Indications for use

Antacid therapy for heartburn and gastroesophageal reflux in patients over 15 years of age

Dosage and method of administration

For use by patients over 15 years of age!

Shake the bottle before use until a homogeneous suspension is obtained. Take 15 ml (1 tablespoon) of the suspension 4 times a day 20-60 minutes after meals and before bedtime. The drug can be taken with water or milk. Do not exceed the maximum daily dose of the drug! The course of treatment is determined by the doctor.

The use of the drug in children Not recommended.

Contraindications

Hypersensitivity to active substances or any other component of the drug. Porphyria. Severe renal failure, as the drug contains magnesium. Childhood. Cachexia.

Special instructions and precautions for use

special instructions

A 2-hour interval should be observed between the use of Maalox and other drugs.

Caution should be given to pregnant and lactating women.

The patient should contact the attending physician in the event of:

Weight loss; difficulty swallowing and persistent abdominal discomfort; digestive disorders, which appeared for the first time, changes in existing digestive disorders; renal failure.

Precautionary measures

Aluminum hydroxide can cause constipation, an overdose of magnesium salts can lead to intestinal hypokinesia; taking high doses of the drug can cause or worsen intestinal obstruction in patients with an increased risk of these complications, i.e. in patients with renal insufficiency, in children under 2 years of age, or in the elderly.

Aluminum hydroxide is poorly absorbed from the gastrointestinal tract, therefore, systemic effects are rarely observed in patients with normal renal function. However, taking high doses of the drug or its long-term use, as well as the use of recommended doses by patients with a low phosphorus content in the diet or children under 2 years of age, can lead to a phosphate deficiency (due to the ability of aluminum to bind phosphate ions), accompanied by increased bone resorption, hypercalciuria and the risk of osteomalacia. In this regard, it is recommended to visit a doctor in case of prolonged use of the drug, as well as in the case of a risk of phosphate deficiency.

When the diet is low in phosphorus, aluminum hydroxide can cause phosphorus deficiency in the body.

In the case of patients with renal insufficiency or those on chronic dialysis, it is necessary to take into account the content of aluminum and magnesium in the preparation. With prolonged use in high doses, including high therapeutic doses, it is possible to develop encephalopathy, dementia, microcytic anemia, or worsening osteomalacia caused by dialysis.

Aluminum hydroxide may be unsafe for porphyria patients on hemodialysis.

If, during therapy, symptoms persist for more than 10 days, as well as in the event of a worsening of the course of the disease, the cause of these symptoms should be established and the treatment should be reviewed.

In patients with renal insufficiency, the combined use of the drug with citrates can lead to an increase in plasma aluminum levels (see section Interaction with other medicinal products).

The medicinal product contains parahydroxybenzoates (methyl and propyl parahydroxybenzoate), which can cause allergic reactions (possibly delayed).

Pregnancy and breastfeeding

Pregnancy

There are no reliable data on teratogenic effects on animals.

To date, in clinical practice, there is no evidence of the development of congenital defects and fetotoxic effects. On the other hand, the possibility of monitoring pregnancies during which the drug has been used is too limited to exclude the possibility of risk. Thus, for safety reasons, the use of the drug during pregnancy is possible only if the potential benefit from its use to the mother justifies the potential risk to the fetus.

It is necessary to take into account the content of aluminum and magnesium ions, which can affect the patency of the gastrointestinal tract:

Magnesium hydroxide salts can cause diarrhea; aluminum salts can cause constipation and worsen the constipation often seen during pregnancy.

Long-term use or taking of the drug in high doses should be avoided.

Breast-feeding

Breastfeeding can be continued during treatment. Aluminum hydroxide in combination with magnesium salts is considered to be compatible with lactation.

Side effect

Side effects observed with the use of the drug are classified into categories depending on the frequency of their occurrence: very often ≥ 10%, often ≥ 1 and

Subject to the prescribed doses, the side effect of the drug is insignificant.

Immune system disorders:

Frequency unknown: hypersensitivity reactions such as pruritus, urticaria, angioedema and anaphylactic reactions.

Gastrointestinal disorders:

Uncommon: diarrhea, constipation, metabolic and digestive disorders.

The frequency is unknown: hypermagnesemia, hyperaluminemia, hypophosphatemia, with prolonged use or with high doses of the drug, as well as with the use of recommended doses by patients with a low phosphorus content in the diet or children under 2 years of age, phosphate deficiency may develop (due to the ability aluminum to bind phosphate ions), accompanied by increased bone resorption, hypercalciuria and the risk of osteomalacia.

In the case of prolonged use and in violation of the renal excretory function, an increase in the level of magnesium and / or aluminum in the blood plasma, the development of a phosphorus deficiency in the body, and encephalopathy are possible.

Elderly patients may have an exacerbation of osteoarticular diseases, Alzheimer's disease.

Overdose

Magnesium overdose does not usually cause toxic reactions in patients with normal renal function. However, magnesium toxicity can develop in patients with renal impairment (see section Precautionary measures).

Symptoms of an acute overdose of a combination of aluminum and magnesium hydroxide include diarrhea, abdominal pain, and vomiting.

High doses of the drug can cause or worsen bowel obstruction in patients at increased risk of these complications.

The toxic effect depends on the concentration of magnesium in the blood serum. Signs of toxic effects:

Decrease in blood pressure; nausea, vomiting; drowsiness, decreased reflexes, muscle fatigue, neuromuscular paralysis; bradycardia, abnormal ECG results; hypoventilation; in the most severe cases, respiratory paralysis, coma, impaired renal or cardiac function may develop; anuric syndrome.

Aluminum and magnesium are excreted through the urinary tract. Treatment of magnesium overdose: rehydration, forced diuresis. In case of renal failure, hemodialysis or peritoneal dialysis is necessary.

Interaction with other medicinal products and other forms of interaction

Antacids interact with some other oral medications.

Combinations requiring safety precautions

WITHquinidine

With simultaneous use with quinidine, an increase in serum concentrations of quinidine and the development of an overdose of quinidine are possible.

In the case of simultaneous oral administration, Maalox can reduce the absorption of various drugs. Therefore, as a precautionary measure, the following drugs are recommended to be taken 2 hours before or 2 hours after taking Maalox:

Acetylsalicylic acid, H2 -antihistamines, ethambutol,isoniazid(oral), atenolol,metoprolol, propranolol,cefdinir, cefpodoxin, chloroquine, cyclins, diflunisal, digoxin,diphosphonates, fexofenadine, iron salts, fluoroquinolones, sodium fluoride, glucocorticosteroids (prednisolone anddexamethasone), indomethacin, ketoconazole,levothyroxine, lansoprazole, lincosamides, phenothiazine antipsychotics,penicillamine, phosphorus (additives), thyroxine,rosuvastatin, sulpirid. With polystyrene sulfonate (kayexalate)

Caution should be exercised when used concomitantly with polystyrene sulfonate (kayexalate) due to the potential risk of reduced efficacy of the resin in binding potassium, the risk of metabolic alkalosis in patients with renal failure, and the risk of intestinal obstruction.

When taken simultaneously with Maalox, the absorption of the above drugs in the gastrointestinal tract is reduced. In the case of a 2-hour interval between taking these drugs and Maalox and a 4-hour interval between taking fluoroquinolones and Maalox, in most cases this unwanted interaction can be avoided.

In all cases, while taking Maalox with other drugs, you must inform the doctor about this.

Combinations to be taken into account

- With salicylates: with the simultaneous administration of salicylates and prolonged use of the drug Maalox in high doses, the excretion of salicylates in the urine may increase as a result of alkalization of urine.

With citrates

When aluminum hydroxide is combined with citrates, an increase in plasma concentrations of aluminum is possible, especially in patients with renal insufficiency.

Manufacturer's address

They know that antacids must be present in the complex of treatment of these diseases. This is the name of drugs that neutralize the effect of digestive juices on the mucous membrane of the upper digestive tract. They do not interfere with the production of hydrochloric acid and enzymes, but prevent them from irritating the walls of the esophagus, stomach and duodenum. Covering them with the thinnest protective film, they create conditions in which inflammation is reduced and cell regeneration is accelerated.

The most famous antacid today is this. It comes in the form of an oral suspension. True, it has two drawbacks: firstly, it is rather difficult to take it "on the run" when a person does not have time to take out a measuring spoon and count his dose, and secondly, it has a side effect - it contributes to constipation. Therefore, people who are always in a hurry, as well as those who have problems with stool or simply prefer maximum convenience, can be advised another domestic remedy - a suspension dosed in sachets or Maalox tablets.

Composition and indications for use

The composition of Maalox is almost identical to that of Almagel - they have the same active ingredients. However, they are more balanced in maalox and that is why it has no effect on stool.

The tool can be taken in the following cases:

- abdominal pain, discomfort, heaviness and nausea with gastritis, peptic ulcer disease, reflux esophagitis, hiatal hernia;

- treatment and prevention of gastritis caused by taking medications (aspirin, prednisolone).

The drug begins to act in 20-30 minutes, and the effect lasts for several hours.

What mistakes can you make when taking Maalox?

The medicine is used very simply: one tablet (or 1 sachet of suspension, 15 ml) before each meal, and again shortly before bedtime to protect the stomach at night - only 4 times. Other antacids are used in this way. However, even with such a banal scheme, patients can make mistakes.

For example, many people drink Maalox along with other medications, while putting a handful of pills in their mouths at the same time. However, treatment with this remedy, along with its simplicity, requires a special attitude - it must be drunk separately, for an hour, or better for two, separating it from food and other medications. Otherwise, food and liquid wash it off the walls of the stomach, and other drugs cannot "break through" through the film created by maalox.

Almost all patients, despite the experience they have already gained with other medications, expect the drugs to act “at the tip of the needle” - a quick one that occurs immediately after the administration of the drug. Of course, Maalox is a quick-acting remedy, but not instantaneous. While it is distributed over the mucous membrane and "soothes" the irritated surface, it takes about 20-30 minutes. Some of the patients do not have the patience to wait for this, so after 3-5 minutes they take another pill, and another ... a large volume of medication is required. He begins to take the drug in the "intensive therapy" mode, which can affect his health: in large doses, maalox inhibits the absorption of nutrients - metal ions, micro- and macroelements, which may lead to electrolyte and metabolic disturbances.

The Russian person is not only impatient, but also very suspicious, so that drugs are often expected not only to have a quick effect, but also some kind of trick. It happens that the symptoms that have arisen during treatment are attributed in absentia to the side effects of drugs.

For example, at one of the many medical forums, the following question was encountered: “I have black stools. Perhaps this is due to the fact that I am taking Maalox? " Black stools can come from activated charcoal, but does this happen from an antacid pill? Sometimes it happens that beets color the feces in burgundy, and warfarin gives a pink tint to the urine, but this is not the case. Maalox does not cause "unexpected" symptoms, any such signs indicate a disease! The black stool in that patient was most likely caused by bleeding ulcers - and, I must say, not the weakest, if the digested blood gave it that color. So it was just right for this poor fellow to call the ambulance and collect things at the hospital - and he was serenely communicating on the forum ... Let's hope that now everything is all right with him.

Finally, the last of the typical mistakes. Maalox and other antacids often become a "lifesaver" for patients who are treated themselves in no hurry to see a doctor. Why go to him? A pill, another - and everything goes away! Don't be as gullible. Maalox alone "won't get you very far." What if you have not gastritis, as you used to think, but an ulcer?

How to improve the effectiveness of Maalox?

If you have been prescribed this medicine, then you have problems with increased secretion. Unfortunately, one drug is not enough here - an integrated approach is needed. If you wait for the symptoms every time, and then simply "extinguish" them with medicine, recovery will not come soon. Therefore, for the treatment to be meaningful, it must be supplemented with other antisecretory agents.

The best of these belongs to the group of proton pump blockers and is called omeprazole. For greater efficiency, Maalox can be combined with it or its analogs - Nexium, Pantoprazole, Esomeprazole. In principle, there are other drugs of similar action, for example, H2-blockers (famotidine, ranitidine) or anticholinergics (gastrozepine), but they are worse, primarily due to side effects.

Antacids will work much better if you are serious about treatment and follow a diet: no spices, coffee, fatty, fried and other "harmful". By the way, fruits, which, in general, are considered attributes of a healthy diet, are contraindicated in acute diseases of the stomach and intestines: they accelerate peristalsis, which increases pain. Therefore, we switch to jelly, mashed potatoes and porridge! Against the background of such a diet, you will quickly get better, and as a result, even such a good medicine as maalox will not have to take so long.

Analogs, articles Comments (aluminum hydroxide + magnesium hydroxide)

(aluminum hydroxide + magnesium hydroxide)

Registration number:

Trade name: Maalox (Maalox) Dosage form: suspension for oral administration. Composition sachet (15 ml) Active substances Magnesium hydroxide gel, equivalent to magnesium hydroxide 600 mg Aluminum hydroxide gel equivalent to aluminum hydroxide 525 mg

Excipients

Concentrated hydrochloric acid 0.018 ml Citric acid monohydrate 9.82 mg Peppermint essential oil 1.89 mg Mannitol 37.50 mg Methyl parahydroxybenzoate 15.00 mg Propyl parahydroxybenzoate 7.50 mg Sodium saccharin 4.215 mg Sorbitol 70% (non-crystalline) 21 hydrogen 30% (9.75 mg)

Purified water up to 15 ml

Description: A white or almost white, milk-like liquid with a mint scent.

Pharmacotherapeutic group Antacid agent.

Classification code ATC-AO2AX.

Pharmacological action Maalox is a well-balanced combination of magnesium hydroxide and aluminum hydroxide, which provides its high neutralizing

Maalox does not cause constipation. It is used as an adsorbent, enveloping and antacid agent for increased acidic gastric juice. Maalox soothes pain in the upper digestive tract for several hours.

Indications Acute and chronic gastritis, acute gastroduodenitis, chronic gastroduodenitis with normal or increased secretory function in the acute phase. hiatal hernia, reflux esophagitis, gastric ulcer and duodenal ulcer, heartburn after dietary errors, medication and alcohol, coffee, nicotine abuse.

Contraindications Hypersensitivity to the components of the drug, chronic renal failure, pregnancy, Alzheimer's disease, hypophosphatemia, Use the drug with caution in children under 12 years of age, as well as women and the period of breastfeeding,

Method of application and dose Maalox is usually taken 1-1.5 hours after a meal or in case of pain, Maalox is taken in the form of a suspension in 15 ml (1 packet). Before use, homogenize the suspension by carefully kneading the bag between your fingers. Squeeze the contents of the bag into a spoon or mouth.

For children, the dosage is determined by the attending physician. If necessary, you can take an additional dose of the drug two hours after the previous dose, but not more than 6 doses per day.

Side effects Subject to the prescribed doses, the side effects of the drug are negligible. Sometimes observed: nausea, vomiting, change in taste, constipation. With prolonged use in high doses, hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, oteoporosis, hypermagnesemia, hyperaluminaemia, encephalopathy, nephrocalcinosis, renal dysfunction. In patients with concomitant renal failure, thirst, a decrease in blood pressure, and hyporeflexia may be observed.

Interaction with other drugs In the case of simultaneous oral administration, Maalox may reduce the absorption of various drugs. Therefore, as a precautionary measure, other drugs are recommended to be taken either 2 hours before taking Maalox5 or 2 hours after it. In all cases of simultaneous administration of Maalox with other drugs, it is necessary to inform the doctor.

Special instructions Strict monitoring of the condition of patients with renal failure is required, as well. in case of the appearance of the first symptoms of the above side effects, the use of the drug should be stopped immediately. High doses of the drug are contraindicated in this category of patients.

Release form Suspension in 15 ml bags, 30 pieces per package.

Storage conditions Store at a temperature not exceeding 25 ° C, out of reach of children.

Shelf life is 3 years. Do not use the drug after the expiry date indicated on the package.

Conditions of dispensing from pharmacies Without a doctor's prescription,

Produced by Aventis Pharma Sp.A., Italy. Viale Europa, 11, Origio, Varese, Italy, Consumer claims should be sent to the address of the company's representative office in Russia: 101000, Moscow, Ulansky pereulok, 5

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medi.ru

Maalox suspension instructions for use

Maalox is a combined drug with antacid, adsorbent, enveloping, choleretic and carminative action.

The drug is produced in the form of tablets and suspensions. The suspension is a white, milk-like substance with a mint odor. The suspension is available in glass dark bottles of 250 ml and in sachets of 10-15 ml.

The preparation contains active substances magnesium hydroxide and aluminum hydroxide and auxiliary substances - purified water, hydrogen peroxide, non-crystalline 70% sorbitol, sodium saccharinate, propyl parahydroxybenzoate, concentrated hydrochloric acid, methyl parahydroxybenzoate, mannitol, essential oil mint, citric acid monohydrate.

pharmachologic effect

Suspension maalox, without causing secondary hypersecretion, neutralizes hydrochloric acid in the stomach and reduces the peptic activity of gastric juice.

Once in the stomach, the suspension has an enveloping and absorbing effect, protects the mucous membrane of the gastrointestinal tract from damage, and soothes painful sensations in the upper parts of the digestive system for several hours.

Indications for the use of the drug

Suspension maalox is successfully used for chronic and acute gastritis, hiatal hernia, exacerbated chronic gastroduodenitis with increased or normal secretory function, duodenal ulcer and stomach, dyspeptic symptoms that have arisen after taking certain drugs (corticosteroids, NSAIDs, etc.) , as well as for pain and discomfort in the epigastrium, excessive alcohol consumption, sour belching.

Contraindications

Suspension maalox is contraindicated in case of hypersensitivity to its components, hypophosphatemia, Alzheimer's disease, severe renal dysfunction. The drug should be taken with caution during pregnancy, during breastfeeding and in children under twelve years of age.

Method of administration and dosage

The drug is taken orally an hour or two after a meal, if painful sensations occur - immediately. Adults take 15 ml (one sachet or tablespoon of suspension) three to four times a day. Shake the bottle well before using the suspension. The bag is kneaded with your fingers, its contents can be squeezed into your mouth or into a spoon.

With reflux esophagitis, the drug is taken a few minutes after a meal. The course of treatment lasts no more than two to three months. The dosage for children is determined by the doctor.

Side effects

If you follow the doctor's prescription and do not take high doses of the drug, then the side effects are insignificant. Sometimes constipation, changes in taste, nausea, vomiting occur.

Long-term and uncontrolled use of Maalox suspension can provoke renal dysfunction, nephrocalcinosis, encephalopathy, hyperaluminaemia, hypermagnesemia, osteoporosis, osteomalacia, hypercalciuria, hypocalcemia, hypophosphatemia. In old age, an exacerbation of Alzheimer's disease, osteoarticular diseases is possible. Patients with concomitant renal failure may experience severe thirst, their blood pressure may decrease, and hyporeflexia may occur.

Application during pregnancy and lactation

Interaction

Simultaneous administration of Maalox with other drugs is possible, but it must be borne in mind that the suspension reduces their absorption. In this case, the drugs must be taken either two hours after taking Maalox, or two hours before it.

Maalox analogs of the drug Maalox analogs of the drug. Indications for the use of maalox analogs.

Phosphalugel for breastfeeding Phosphalugel for breastfeeding. Antacids for breastfeeding. How do medications affect the child's body? Phosphalugel - for children under one year old. Indications and contraindications.

Phosphalugel - how to take Phosphalugel - how to take. Indications for use, method of administration and contraindications. Side effects, overdose, interactions with other medications.

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Home / Advice / Medicines for gastrointestinal diseases / Maalox suspension instructions for use

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Maalox suspension: instructions for use

  • Maalox oral suspension
  • Maalox chewable tablets

The composition of one sachet of suspension (15 ml):

Active substances:

Magnesium hydroxide 600 mg

Aluminum hydroxide 525 mg

Excipients:

Concentrated hydrochloric acid 0.018 ml

Citric acid monohydrate (EZZO) 9.82 mg

Peppermint essential oil 1.89 mg

Mannitol (E421) 37.50 mg

Methyl parahydroxybenzoate (E218) 15.00 mg

Propyl parahydroxybenzoate (E216) 7.50 mg

Sodium saccharinate (E954) 4.215 mg

Sorbitol 70% (non-crystallizing) (E420) 214.3 mg

Hydrogen peroxide 30% (9.75 mg)

Purified water up to 15 ml

a creamy liquid that resembles milk in appearance, has a sweet taste and a mint smell.

Maalox is a well-balanced combination of magnesium hydroxide and aluminum hydroxide, which provides its high ability to neutralize acidic stomach contents and protect the esophageal and gastric mucosa.

It is used as an absorbent, enveloping and antacid agent with increased acidity of gastric juice. Maalox relieves pain in the upper digestive tract for several hours. Maalox does not cause constipation.

Magnesium and aluminum hydroxides are considered topical antacids, which are practically not absorbed from the gastrointestinal tract when taken in recommended doses and, accordingly, do not have general effects on the body.

Antacid therapy for heartburn and gastroesophageal reflux, accompanied by the reflux of acidic gastric contents into the esophagus. Symptoms are belching, regurgitation, painful and difficult swallowing, pain in the epigastric region (just below the projection of the solar plexus), appearing soon after eating and aggravated with inclined movements. The therapy can be used in patients over 15 years of age.

Severe renal failure, as the drug contains magnesium.

Hypersensitivity to the components of the drug.

Age up to 15 years.

Fructose intolerance.

In animal studies, there has been no clear indication of the presence of a teratogenic effect in aluminum hydroxide and magnesium hydroxide. To date, no specific teratogenic effects have been identified when using Maalox during pregnancy, however, due to the lack of clinical experience, its use during pregnancy is possible only if the potential benefit from its use to the mother justifies the potential risk to the fetus.

It is necessary to take into account the content of aluminum and magnesium ions, which can affect the patency of the gastrointestinal tract:

Magnesium hydroxide salts can cause diarrhea;

Aluminum salts can cause constipation and worsen the constipation often seen during pregnancy.

Avoid prescribing the drug during pregnancy in high doses and for a long time.

Breastfeeding can be continued during treatment. Magnesium is considered to be compatible with lactation.

For use by patients over 15 years of age!

Maalox is usually taken 1-1.5 hours after a meal or when pain occurs. Maalox in the form of a suspension is taken in 15 ml (1 sachet). Before use, homogenize the suspension by carefully kneading the bag between your fingers. Squeeze the contents of the sachet into a spoon or mouth without diluting with water.

If necessary, you can take an additional dose of the drug two hours after the previous dose, but not more than 6 doses per day.

Subject to the prescribed doses, the side effect of the drug is insignificant.

In rare cases, when using the drug, constipation, nausea, vomiting, and a change in taste may occur.

In the case of prolonged use and in violation of the renal excretory function, an increase in the level of magnesium and / or aluminum in the blood plasma, the development of a phosphorus deficiency in the body, and encephalopathy are possible.

Elderly patients may have an exacerbation of osteoarticular diseases, Alzheimer's disease.

Magnesium overdose does not usually cause toxic reactions in patients with normal renal function. However, magnesium toxicity can develop in patients with renal impairment (see PRECAUTIONS). The toxic effect depends on the concentration of magnesium in the blood serum.

Signs of toxic effects:

Decrease in blood pressure;

Nausea, vomiting;

Drowsiness, decreased reflexes, muscle fatigue, neuromuscular paralysis;

Bradycardia, abnormal ECG results;

Hypoventilation;

In the most severe cases, respiratory paralysis, coma, renal or cardiac dysfunction may develop;

Anuric syndrome.

Treatment of magnesium overdose: rehydration, forced diuresis. In case of renal failure, hemodialysis or peritoneal dialysis is necessary.

Antacids interact with some other oral medications.

Combinations requiring safety precautions

With quinidine

With simultaneous use with quinidine, an increase in serum concentrations of quinidine and the development of an overdose of quinidine are possible.

In the case of simultaneous oral administration, Maalox can reduce the absorption of various drugs. Therefore, as a precautionary measure, the following drugs are recommended to be taken 2 hours before or 2 hours after taking Maalox:

H2-antihistamines, ethambutol, isoniazid (oral), atenolol, metoprolol, propranolol, cefdinir, cefpodoxin, chloroquine, cyclins, diflunisal, digoxin, diphosphonates, fexofenadine, iron salts, fluoroquinocorticolone, indocinosteroids, and fluoro-cinerone , keyexalat, ketoconazole, lansoprazole, lincosamides, phenothiazine antipsychotics, penicillamine, phosphorus (additives), thyroxine.

When taken simultaneously with Maalox, the absorption of the above drugs in the gastrointestinal tract is reduced. In the case of a 2-hour interval between taking these drugs and Maalox and a 4-hour interval between taking fluoroquinolones and Maalox, in most cases this unwanted interaction can be avoided.

In all cases of simultaneous administration of Maalox with other drugs, it is necessary to inform the attending physician.

Combinations to be taken into account

With salicipates

With the simultaneous administration of salicylates and prolonged use of the drug Maalox in high doses, the excretion of salicylates in the urine may increase as a result of alkalization of urine under the influence of the drug Maalox.

With citrates

When aluminum hydroxide is combined with citrates, an increase in plasma concentrations of aluminum is possible, especially in patients with renal insufficiency.

A 2-hour interval should be observed between the use of Maalox and other drugs.

With extreme caution should be prescribed to pregnant and lactating women.

The patient should contact the attending physician in the event of:

Weight loss;

Difficulty swallowing and persisting despite treatment for abdominal discomfort

Digestive disorders, which appeared for the first time, changes in existing digestive disorders;

Renal failure.

This drug is contraindicated in patients with fructose intolerance, glucose or galactose malabsorption syndrome, or sucrase-isomaltase deficiency, and should be used with caution in diabetic patients due to the presence of sorbitol and sucrose in it.

When the diet is low in phosphorus, aluminum hydroxide can cause phosphorus deficiency in the body.

In the case of patients with renal insufficiency or those on chronic dialysis, it is necessary to take into account the content of aluminum and magnesium in the preparation. With prolonged use in high doses, including high therapeutic doses, it is possible to develop encephalopathy, dementia, microcytic anemia, or worsening osteomalacia caused by dialysis.

Aluminum hydroxide may be unsafe for porphyria patients on hemodialysis.

Suspension in 15 ml sachets, 30 sachets per package together with instructions for use.

Store at a temperature not exceeding 25 ° C, out of the reach of children.

Over the counter.

  • Maalox mini
  • Rennie
  • Gefal-belmed
  • Magnagel

Self-medication can be harmful to your health. You should consult your doctor and read the instructions before use.

apteka.103.by

Maalox suspension: instructions for use and patient reviews

Diseases of the gastrointestinal tract nowadays occupy a leading position. Many factors contribute to this: lifestyle, stress, unhealthy diet, drug abuse, poor environmental quality.

Under these conditions, the awareness of the population about effective drugs with a minimum of side effects becomes extremely important. We hope that the description below of the main properties of Maalox will raise the awareness of all those who suffer from gastrointestinal diseases and allow them to make an adequate decision.

Pharmacological features

Maalox is a complex drug with a set of properties. The drug, like baking soda, helps to neutralize hydrochloric acid, reduces its concentration without a secondary increase in secretion.

This creates a protective layer on the stomach lining, which reduces the likelihood of irritating food. It stimulates the formation of bile, and promotes its excretion into the duodenum, which increases the efficiency of the digestive process and cleanses the liver of excess bile.

Due to its ability to adsorb substances, maalox reduces the level of harmful substances accumulated in the intestines. The carminative properties of the drug help to get rid of intestinal gases.

The pharmacological features of Maalox suspension are aimed at increasing the efficiency of the digestive process, cleaning the intestines, and also preventing the destruction of cells of its mucous membrane.

Suspension composition

In maalox, substances with therapeutic activity are magnesium hydroxide and aluminum hydroxide.

Substances that perform an auxiliary function include:

  • distilled water;
  • hydrogen peroxide;
  • non-crystalline sorbitol (70%);
  • sodium saccharinate;
  • hydrochloric acid;
  • mint essential oil;
  • lemon acid.

Can Rennie be taken during pregnancy? What is the dosage?

What is intestinal dolichosigma? Read about the symptoms and treatment of the disease in this article.

Diseases for which Maalox is prescribed

Such diseases include:

  • peptic ulcer of the intestine and stomach, mainly in acute form;
  • acute and chronic gastroduodenitis;
  • gastritis proceeding against the background of normal or increased secretion;
  • hernia, localized in the area of ​​the diaphragm;
  • reflux;
  • dyspepsia of different genesis,
  • digestive disorders when overeating and eating poor-quality food;
  • heartburn caused by poor diet.
  • food poisoning;
  • dysfunction of the liver and pancreas as a means of reducing the negative impact on the functioning of the stomach and intestines.

How to apply?

The regularity and dosage of taking the suspension depends on the age of the patient, the diagnosis and the severity of the manifestation of the disease.

Since maalox is used to improve digestion, you need to take it an hour or two after a meal. The only exceptions are cases of pain after eating. This is a signal to take the drug immediately.

The therapeutic effect of Maalox lasts for two hours after ingestion. This follows in the formation of the regimen of food intake.

Dosage for adults: one sachet or 1 tbsp. a spoonful of suspension after each meal. However, Maalox should not be taken more often than three to four times a day.

When treating reflux esophagitis, the agent must be taken immediately after a meal.

The treatment course should not exceed three months. The optimal period is two months.

The dosage of the drug for children is associated not only with the low weight of the child and the peculiarities of its physiology, but also with the danger of washing out some elements. The maximum duration of the course for children is 1 month.

It is necessary to take the suspension 1.5 hours after a meal. A single dose depends on the age of the child. Age up to a year - 0.5 teaspoon, from 1 - 5 years - a full teaspoon, 5 - 15 years - one dessert spoon at a time. Regularity of admission - 2 - 3 times a day.

Contraindications

You should refrain from using this tool in the following cases:

  • an allergic reaction;
  • hypophosphatemia;
  • a confirmed diagnosis of Alzheimer's disease;
  • severe symptoms of renal failure;
  • during pregnancy and breastfeeding;
  • treatment of children under 12 years of age.

The last two contraindications are associated not so much with the danger of this remedy for the child's body, but with the fact that with a prolonged course, too much removal of two important elements from the body - phosphorus and calcium - is possible.

This entails an increase in bone fragility, as well as a slowdown in the growth of children at all age stages.

Recently, this drug has begun to be used for the treatment of children, but in small courses, accompanied by additional intake of sources of calcium and phosphorus.

Caution should be exercised when taking Maalox in patients diagnosed with osteoporosis.

Adverse Reactions

This drug is considered to be reasonably safe, but side effects may occur when using it. These include:

  • allergic reactions;
  • stool disorders;
  • vomiting and nausea;
  • violation of taste perception;
  • an increase in the amount of magnesium and aluminum in the blood;
  • a decrease in the amount of phosphorus and calcium in the blood;
  • increased bone fragility;
  • the formation of kidney stones;
  • increased need for water;
  • lowering blood pressure;
  • decreased mental alertness;
  • encephalopathy.

The listed side effects do not appear often and are usually the result of self-medication without taking into account contraindications. There may be cases of prescribing a remedy to a person suffering from diseases listed in the list of contraindications, but without a diagnosis.

This is especially true in cases of provoking encephalopathy and dementia at the initial stage of the development of Alzheimer's disease.

Overdose and special instructions

As mentioned above, most of the side effects occur with unexplained diagnoses from the list of contraindications.

In addition, side effects can be provoked even if the permissible single dosage is not observed or if the treatment course is too long.

The latter is one of the options for overdose. In order to avoid side effects if long-term treatment is required, the course must be divided into fragments. The treatment course should be interrupted for at least 10 days, which will allow the body to restore the balance of essential substances.

An overdose is manifested by the following symptoms: diarrhea, pain; cramps in the intestines; nausea, vomiting, behavioral disturbances due to exacerbation of encephalopathy. In this case, you should ensure peace, drink plenty of fluids, and take moderate doses of diuretics. To eliminate vomiting and intestinal cramps, you can use peppermint infusion, to eliminate diarrhea - an infusion of oak bark.

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Analogs

The analogs of the drug include those drugs that have a similar set of substances that have a therapeutic effect, and differ insignificantly in all other indicators. On this basis, the following drugs can be attributed to maalox analogues: ajiflux, almagel, almol, alumag, anacid forte, gastracid, rivolox.

Average drug price

The price of maalox suspension varies depending on the region.

The average price of a 250 ml bottle is 390 rubles.

The average price of one bag of suspension is 22 rubles.

Maalox is an antacid and coating agent with an acid-neutralizing effect.

The drug neutralizes free hydrochloric acid without causing secondary hypersecretion of hydrochloric acid. Due to the increase in pH, when it is taken, the peptic activity of the gastric juice decreases.

It has an absorbent and enveloping effect, due to which the influence of damaging factors on the mucous membrane is reduced.

Algeldrat (aluminum hydroxide) and magnesium hydroxide are local antacids and are practically not absorbed when taken in therapeutic doses, therefore there are no systemic effects.

Indications for use

What does Maalox help with? According to the instructions, the drug is prescribed in the following cases:

  • acute gastritis (stomach inflammation);
  • chronic gastritis with normal or increased secretory function (secretion of gastric juice) in the acute phase;
  • hernia of the esophageal opening of the diaphragm;
  • peptic ulcer of the stomach and duodenum in the acute phase;
  • discomfort in the stomach after errors in diet, medication and abuse of coffee, alcohol, nicotine.

Instructions for use of Maalox, dosages

The tablets are taken orally, chewing thoroughly. Recommended dosage: 1-2 tablets 3-4 times a day 1-2 hours after meals and before bedtime.

In case of reflux esophagitis, the interval between meals and pills should be shortened. The course of treatment is no more than 2-3 months. For occasional use, a single dose of 1-2 tablets is indicated.

For the treatment of acute inflammatory processes, a single dose of the drug is 3 tablets, which is taken half an hour before meals.

The suspension is taken orally: 1 sachet 1-2 hours after a meal and at night or in the event of heartburn or pain in the epigastric region; 1 tablespoon (suspension in vials) 3-4 times a day after 1-2 hours after meals and at night.

Before use, the suspension in the vials should be shaken, in the sachet - thoroughly knead between the fingers (homogenize).

The daily dose of Maalox is no more than 90 ml of suspension or 6 sachets. With reflux esophagitis, the drug is taken 30-60 minutes after a meal, with gastric ulcer - 30 minutes before a meal.

The dosage of the drug for children is determined on an individual basis.

The duration of taking tablets or suspensions is no more than 2-3 months. In case of occasional use, it is recommended to use 1-2 tablets or 15 ml of suspension once (for example, with discomfort after errors in the diet).

Side effects

The instruction warns of the possibility of developing the following side effects when prescribing Maalox:

  • Rarely: the development of a phosphorus deficiency in the body (possibly with prolonged use in high doses and is associated with the presence of algeldrate in the composition of the drug).

Application in high doses is contraindicated in patients with renal insufficiency. During the period of application of the drug in medium and low doses in this category of patients, it is necessary to control the phosphorus content in the body. When the first symptoms of phosphorus depletion in the body appear, the drug should be canceled immediately.

Contraindications

It is contraindicated to prescribe Maalox in the following cases:

  • known hypersensitivity to auxiliary ingredients of a separate dosage form of the drug or directly to aluminum and / or magnesium hydroxide (active ingredients of Maalox);
  • Alzheimer's disease;
  • severe renal dysfunction; habitual constipation;
  • hypophosphatemia;
  • severe abdominal pain of unspecified genesis (including cases of suspected surgical pathology);
  • chronic diarrhea;
  • intolerance to fructose, sucrase-isomaltase deficiency, malabsorption syndrome (impaired absorption) of galactose and glucose;
  • the presence of indications in children under 15 years of age.

Overdose

Currently, no cases of drug overdose have been reported.

Analogues Maalox, price in pharmacies

If necessary, you can replace Maalox with an analogue of the active substance - these are drugs:

  1. Agiflux,
  2. Alumag,
  3. Almagel,
  4. Palmagel,
  5. Maalukol,
  6. Rivolox,
  7. Phosphalugel.

When choosing analogs, it is important to understand that the instructions for the use of Maalox, the price and reviews for drugs of a similar action do not apply. It is important to consult a doctor and not make your own replacement of the drug.

Price in Russian pharmacies: Maalox suspension 15 ml - from 21 to 27 rubles, chewable tablets. sugar-free 20 pcs. - from 187 to 235 rubles, according to 481 pharmacies.

The tablets should be stored at room temperature. Shelf life is 2 years. Store the oral suspension in a cool place, do not freeze. Shelf life is 3 years.