Kagocel is a new generation antiviral drug. Kagocel - antiviral effect, instructions for use (tablets) for adults, for children, drug analogues, reviews, price Scheme of using Kagocel

Respiratory diseases, frequent colds, flu ... Any child can avoid these diseases even with proper care. His immunity is still being formed, it is difficult for him to resist virus attacks.

For most parents, there is no more pressing problem than finding a medicine that will help cope with a cold and prevent it from recurring in the future.

The antiviral drug Kagocel belongs to the group of drugs that promote the production of interferon. It relieves babies from colds and provides protection for the developing organism.

At what age can Kagocel be given to children, how often should the drug be taken? The answers to these questions, instructions for the use of Kagocel for children will be discussed in detail in our article.

Composition, effect on the child's body

Kagocel - low toxicity antiviral... Pediatricians note its rather high safety. The medicine works equally well at any stage of the disease.

The composition includes a plant active substance - a copolymer, which is extracted from cotton.

The active substance stimulates the body's production of interferon protein. Interferon's functions include:

• preventing the spread of viruses;
• restoration of damaged cells;
• increasing the immunity of cells to viral attacks;
• relieving cold symptoms;
• increased immunity.

The advantage of the remedy is that it does not accumulate in the body and does not cause side effects. The medicine is available in tablets for oral administration. Each tablet contains 12 mg of active ingredient.

Read about how the drug works for the treatment and prevention of SARS and influenza in drops for children.

Indications

According to statistics, children of preschool and primary school age suffer 5-8 ARIs per year. In cities, this figure rises to 10-12 cases annually.

Kagocel successfully fights viruses of various origins... The tool is prescribed for the treatment and prevention of the following diseases:

According to the results of clinical studies, the use of Kagocel can reduce the number of babies with ARVI by 3 times.

Kagocel is also effective in such cases, when children have cases of the spread of a dangerous disease - chickenpox - in children's groups. Treatment will destroy the virus at the initial stage of infection. If the symptoms of chickenpox do appear, taking the medication will speed up your recovery.

Kagocel only contributes to a quick recovery. The use of the drug should not cause the cancellation of other methods of treatment.

Learn how to protect your child from colds and flu during the sick season in this video:

Contraindications

Despite the high safety of the product, it is necessary to highlight contraindications:

• age up to 3 years;
• tendency to allergic reactions;
• lactose immunity;
• hypersensitivity to drug components.

With great care, Kagocel is prescribed for children suffering from renal, endocrine, neurological and mental diseases.

For babies in these risk groups use without a doctor's recommendation is not recommended.

In case of an overdose, headaches, abdominal pain, nausea, vomiting, and anxiety may occur. When these symptoms occur, the patient is washed with stomach and given activated charcoal at the rate of 1 tablet per 10 kg of body weight.

How to take, dosage

The tool overcomes viral infections, does not allow them to gain a foothold inside the body, and limits their reproduction. The interferon level rises 3-4 hours after ingestion, and the maximum effect is achieved after 2 days.

How to drink Kagocel correctly? In case of viral infections in patients over 6 years old, it is recommended to take 1 tablet 3 times a day before meals or a few hours after it.

After 2 days, the dose is reduced to 1 tablet 2 times a day. The course of treatment lasts 4 days.

If Kagocel is taken for prophylactic purposes, the dose for children is 1 tablet once a day.

After two days, a break of five days is required, then the drug is repeated. To clarify the required dosage, consult a doctor.

Kagocel is taken orally, without chewing, with several sips of water. The time of admission should be closely monitored. If the medicine has not been taken on time, double dosing is best avoided. The medicine is not recommended with meals, as the process of digesting food reduces its effectiveness.

Why is the drug not recommended for babies under 3 years old? This limitation is due to the fact that patients in this age group did not participate in drug trials.

Children 3-6 years old take 1 tablet 2 times a day (2 days), then 1 tablet a day (2 more days).

Interaction with other substances

Kagocel goes well with immunostimulants and antibiotics... It also complements the effectiveness of other antiviral medications.

The therapeutic effect of the drug will be low if you start taking it later than 4 days after the onset of symptoms of the disease. If the agent is used for prophylaxis, there are no restrictions on the time of admission.

Price, conditions and shelf life

The drug is stored in a dry place out of the reach of children at a temperature not exceeding 25 ° C. Shelf life is 2 years. The price of the drug is from 217 to 250 rubles.

In our material, we will tell you about the popular antipyretic agent for children - you will learn about the dosage rules and contraindications.

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- a drug of pronounced antiviral, antimicrobial, immunomodulating action. The drug stimulates the synthesis of alpha, beta and gamma interferons, the action of which is aimed at inhibiting the production of RNA and virus proteins.

The therapeutic effect after the first intake of Kagocel is noted after 4 hours, after which the level of interferons is kept up to 4-5 days. The drug has no toxic effect on the body, does not accumulate in tissues, provided that the recommended dosages are observed.

Kagocel is combined with other drugs: antibiotics, antiviral and antihistamines, drugs that increase immunity. Due to this, Kagocel is used in complex schemes for the treatment of viral diseases.

Instructions for use

ATX code

J05AX, Other Antivirals

Composition and form of release

Tablets, round, biconvex, cream-colored, interspersed. 1 tablet contains Kagocel - 12 mg.

pharmachologic effect

The central mechanism of action of Kagocel is the ability to induce the production of interferon. Kagocel causes the formation of late interferon in the human body, which is a mixture of alpha and beta interferons with antiviral properties.

Kagocel causes the production of interferon in populations of cells participating in the antiviral response of the body: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells.

When a single dose of Kagocel is taken orally, the serum interferon titer reaches a maximum after 48 hours. The body's interferon response to the introduction of Kagocel is characterized by prolonged (up to 4-5 days) circulation of interferon in the bloodstream.

The dynamics of the accumulation of interferon in the intestine when administered orally with Kagocel does not coincide with the dynamics of the titers of circulating interferon. In the blood serum, interferon production reaches its highest values \u200b\u200b48 hours after taking Kagocel, and in the intestine, the maximum production of interferon is noted after 4 hours.

Kagocel, when administered in therapeutic doses, is non-toxic, does not accumulate in the body. The drug has no mutagenic and teratogenic properties, is not carcinogenic and has no embryotoxic effect.

The drug is excreted from the body, as a rule, through the intestines: after 7 days after administration, 88% of the administered dose is excreted from the body, including 90% with feces and 10% with urine.

Indications for the use of Kagocel

• prevention and treatment of influenza and other acute respiratory viral infections in adults;
• treatment of influenza and other acute respiratory viral infections in children 3 years of age and older;
• treatment of herpes in adults.

Method of administration and dosage

For oral administration.

Adults

For the treatment of influenza and acute respiratory viral infections, it is prescribed in the first 2 days - 2 tablets 3 times a day, in the next 2 days - 1 tablet 3 times a day. For a course lasting 4 days - 18 tablets.

ARVI prevention is carried out in 7-day cycles: 2 days - 2 tablets once a day, a break for 5 days, then repeat the cycle. The duration of the preventive course varies from 1 week to several months.

For the treatment of herpes in adults, 2 tablets are prescribed 3 times a day for 5 days. For a course of 5 days - 30 tablets.

For children

For the treatment of influenza and SARS, children 3-6 years old are prescribed in the first 2 days - 1 tablet 3 times a day, in the next 2 days - 1 tablet 2 times a day. For a course of 4 days - 10 tablets.

For the treatment of influenza and ARVI, children 6 years of age and older are prescribed in the first 2 days - 1 tablet 3 times a day, in the next two days - 1 tablet 2 times a day. Per course - 10 tablets, course duration - 4 days.

Prevention of influenza and ARVI in children 3 years of age and older is carried out in 7-day cycles: two days, 1 tablet once a day, a break for 5 days, then repeat the cycle. The duration of the preventive course is from one week to several months.

Sometimes the individual prophylactic course of taking the drug is extended to 5 months.

Contraindications

• pregnancy;
• children under 3 years old;
• increased individual sensitivity.
• deficiency of lactase, lactose intolerance or glucose-galactose malabsorption syndrome.

Side effects

Allergic reactions are possible.

Special instructions for use

The effectiveness of the treatment with Kagocel is achieved when the drug is prescribed no later than the 4th day from the onset of an acute infection. For prophylactic purposes, the drug is also used immediately after contact with the infectious agent. Kagocel is combined with other antiviral drugs, immunomodulators and antibiotics.

Drug interactions

With the simultaneous use of Kagocel with other antiviral drugs, immunomodulators and antibiotics, an additive effect has been described.

Interaction of Kagocel with alcohol

Kagocel and alcohol are not combined, therefore, you should not consume alcoholic beverages while treating with this drug.

Storage conditions

Store in a dry, dark place out of the reach of children at a temperature not exceeding 25 ° C.

Shelf life

Vacation conditions

Available without a prescription.

Kagocel's price

The average price is 215 rubles.

Kagocel's analogs

• Amizon;
• Amiksin;
• Arbidol;
• Oscillococcinum;
• Remantadine;
• Tamiflu;
• Cycloferon;
• Citovir.

Kagocel should not be replaced with another medication of your own free will. In the absence of a prescribed remedy in the pharmacy network, it is worth seeking advice so that the doctor selects the appropriate drug.

Pharmacodynamics

The main mechanism of action of Kagocel® is the ability to induce the production of interferon. Kagocel® causes the formation of the so-called late interferon in the human body, which is a mixture of a- and b-interferons with high antiviral activity. Kagocel® induces the production of interferon in almost all populations of cells involved in the antiviral response of the body: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When a single dose of Kagocel® is taken orally, the interferon titer in the blood serum reaches its maximum values \u200b\u200bafter 48 hours. The body's interferon response to the introduction of Kagocel® is characterized by prolonged (up to 4-5 days) circulation of interferon in the bloodstream. The dynamics of the accumulation of interferon in the intestine when administered orally with Kagocel® does not coincide with the dynamics of the titers of circulating interferon. In the blood serum, interferon production reaches high values \u200b\u200bonly 48 hours after taking Kagocel®, while in the intestine the maximum production of interferon is noted already after 4 hours.

Kagocel®, when administered in therapeutic doses, is non-toxic, does not accumulate in the body. The drug does not possess mutagenic and teratogenic properties, is not carcinogenic and does not have an embryotoxic effect.

The greatest efficiency in the treatment of Kagocel® is achieved when it is administered no later than the 4th day after the onset of an acute infection. For prophylactic purposes, the drug can be used at any time, including immediately after contact with the infectious agent.

Pharmacokinetics

24 hours after administration into the body, Kagocel® accumulates mainly in the liver, to a lesser extent in the lungs, thymus, spleen, kidneys, and lymph nodes. Low concentration is observed in adipose tissue, heart, muscles, testes, brain, blood plasma. The low content of Kagocel® in the brain is explained by the high molecular weight of the drug, which makes it difficult for it to penetrate the blood-brain barrier. In blood plasma, the drug is mainly in a bound form.

With daily repeated administration of Kagocel®, the volume of distribution varies widely in all the examined organs. The accumulation of the drug in the spleen and lymph nodes is especially pronounced. When taken orally, about 20% of the administered dose of the drug enters the general bloodstream. The absorbed drug circulates in the blood, mainly in the form associated with macromolecules: with lipids - 47%, with proteins - 37%. The unbound part of the drug is about 16%.

Excretion: the drug is excreted from the body mainly through the intestines: after 7 days after administration, 88% of the administered dose is excreted from the body, including 90% through the intestines and 10% by the kidneys. The drug was not found in the exhaled air.

Recipe (international)

Rp .: Kagocel 0.012
D.t.d.N. 20 in tab.
S. In the first 2 days, 1 tablet 3 times a day, in the next 2 days - 1 tablet 2 times a day.

pharmachologic effect

Kagocel is a synthetic drug of the group of interferon inducers.

Kagocel is a substance of the polyphenol group obtained by synthesis from water-soluble carmoxymethylcellulose and cottonseed polyphenol.

The drug has antimicrobial, antiviral, immunostimulating and radioprotective effects. The mechanism of action of the drug is based on its ability to stimulate the synthesis of endogenous interferon proteins, in particular, under the action of the drug, there is an increase in the amount of alpha, beta and gamma interferons. The drug enhances the production of interferon in various cells involved in the formation of the immune response, including macrophages, granulocytes, T- and B-lymphocytes, endothelial cells and fibroblasts. Interferons are specific proteins with pronounced antiviral activity, due to the activation of protein kinase and adelital synthetase enzymes, interferons inhibit the synthesis of virus proteins and viral RNA. In addition, interferons have direct and indirect antitumor activity.

After a single oral administration of the drug, the maximum production of interferon in the intestine is noted after 4 hours, and the maximum concentration of interferon in the blood plasma is reached within 48 hours, while the high level of interferon in the blood plasma remains up to 4-5 days after the use of Kagocel. The drug in therapeutic doses does not have a toxic effect on the body, practically does not accumulate in organs and tissues, does not possess teratogenic, mutagenic and embryotoxic effects.

24 hours after oral administration of the drug, its maximum concentrations are observed in the tissues of the liver, lungs, spleen and kidneys, as well as in the thymus and lymph nodes. Due to the large size of the molecule, Kagocel practically does not penetrate the blood-brain barrier and its content in the tissues of the central nervous system is insignificant.
About 20% of the taken dose of the drug is absorbed into the systemic circulation, in plasma the drug binds to proteins and lipids, about 16% of the drug is present in the blood plasma in free form.
The drug is excreted mainly in the feces, a small part of the drug is excreted in the urine (no more than 10%).

Mode of application

For adults: For oral administration.

For the treatment of influenza and ARVI, adults are prescribed in the first two days - 2 tablets 3 times a day, in the next two days - one tablet 3 times a day. In total, the course - 18 tablets, course duration - 4 days.

Prevention of influenza and ARVI in adults is carried out in 7-day cycles: two days - 2 tablets once a day, a break for 5 days, then repeat the cycle. The duration of the preventive course is from one week to several months.

For the treatment of herpes in adults, 2 tablets are prescribed 3 times a day for 5 days. In total, the course - 30 tablets, the duration of the course - 5 days.

For the treatment of influenza and ARVI, children aged 3 to 6 years are prescribed in the first two days - 1 tablet 2 times a day, in the next two days - one tablet 1 time a day. In total, the course - 6 tablets, course duration - 4 days.

For the treatment of influenza and acute respiratory viral infections, children aged 6 years and over are prescribed in the first two days - 1 tablet 3 times a day, in the next two days - one tablet 2 times a day. In total for the course - 10 tablets, the duration of the course - 4 days.

Prevention of influenza and ARVI in children aged 3 years and older is carried out in 7-day cycles: two days - 1 tablet 1 time per day, 5 days off, then repeat the cycle. The duration of the preventive course is from one week to several months.

Indications

Kagocel is used in adults and children aged 3 years and older as a prophylactic and therapeutic agent for influenza and other acute respiratory viral infections (ARVI), as well as a therapeutic agent for herpes in adults.

Contraindications

Increased individual sensitivity to Kagocel.

Hereditary intolerance to galactose, lactase deficiency Lapa, impaired absorption of glucose-galactose.

The drug is not used for the treatment of women during pregnancy and lactation, as well as for the treatment of children under the age of 6 years.

Side effects

The drug is usually well tolerated by patients; in isolated cases, allergic reactions may develop.

Release form

Tablets of 10 pieces in a blister, 1 blister in a carton box.

ATTENTION!

The information on the page you are viewing was created for informational purposes only and does not in any way promote self-medication. The resource is intended to familiarize healthcare professionals with additional information about certain medications, thereby increasing their level of professionalism. The use of the drug "" without fail provides for a consultation with a specialist, as well as his recommendations on the method of application and dosage of your chosen medicine.

Associate Professor of the Department of Pediatrics-1 at Osh State University. Physician neonatologist-resuscitator
RS OMKB. Candidate of Medical Sciences.

Kagocel with instructions for use is used for children as an antiviral and immunomodulatory drug. Kagocel as an active ingredient is not used in other medicines, it is not included in the WHO registry. However, the remedy is recognized as the most prescribed in Russia. How effective and safe is the drug, what do patients and doctors say about it?

According to the instructions, Kagocel is not used to treat children from 2 years of age. Younger patients are prescribed:

1. Orvirem is a syrup with rimantadine. Assigned to children from 1 year old with flu.
2. - a remedy based on antibodies to human gamma interferon. The tablet is dissolved in a teaspoon of boiled water, you can take it from 1 month of age. Effective for ARVI, flu, intestinal infections.
3. Citovir-3 is available in powder form for solution preparation. Allowed for admission from 1 year. The advantage of the drug is its use in children with atopic dermatitis. Prescribed for viral infections.
4. - Oseltamivir-based flu medicine, prescribed from 1 year. Release form - capsules and powder for suspension preparation.

The therapeutic course lasts 4 days:

1. According to the instructions for children 3 years old, the first two days Kagocel drink 1 tablet twice a day.
2. Then take 2 days, 1 tablet once a day.

For the course of treatment, 6 tablets are taken. The medicine is used regardless of food intake.

If the child is 5 years old, then according to the instructions for therapeutic purposes, Kagocel is given in the same dosage as for children 3 years old. For the prevention of viral diseases, a seven-day drug intake cycle is used. On the 1st and 2nd day, the child should drink 1 tablet, then a break is taken for 5 days. The course lasts from 7 days to several months. According to the instructions for use, Kagocel is used for prophylaxis in children:

• during the seasonal spread of viral diseases;
• after contact with a sick person.

In order to prevent infection, the agent is prescribed from 3 years old, 1 tablet per day.

Kagocel, according to the instructions for use, for children from 6 years old is prescribed in the following doses:

• the first two days, one tablet three times a day;
• the next two days, take one tablet twice a day.

In just a four-day course of treatment, the child must drink 10 tablets. The medicine is taken before or after meals.

For children from 7 to 10 years old and older, Kagocel is prescribed for therapeutic and prophylactic purposes for ARVI and influenza. The same doses of the drug are observed as for a six-year-old child.

It is recommended to start treatment with this remedy no later than the fourth day of illness. At this stage, the body already independently produces interferons of the desired type, and there is no need to take stimulants.

The medicine is round and creamy in color. The active substance is Kagocel, a synthetic inducer of interferon. The tool was developed by Russian scientists and has no analogues in terms of the active substance. Among the auxiliary ingredients is lactose.

Kagocel acts on cells that are responsible for the body's immune response to a viral attack. The result is late alpha and beta interferon. This ensures the antiviral effect of the drug.

After taking the drug, the maximum production of interferons in the intestine is observed after 4 hours. The peak concentration in blood plasma is observed after two days. These indicators persist for another 4-5 days. Other organs into the tissues of which Kagocel penetrates:

• spleen;
• liver;
• the lymph nodes;
• kidneys;
• lungs.

This effect is recorded 24 hours after using the medicine inside. The withdrawal of the substance is carried out by about 90% with feces, slightly less than 10% comes out with urine.

Indications for the appointment of Kagocel

• flu;
• acute respiratory viral infections;
• herpes infections in adults;
• urogenital chlamydia (for adults, in combination with other medicines).

It is possible to use the medicine for prophylaxis during the seasonal spread of viral infections.

Contraindications

• children under 3 years old;
• intolerance to galactose;
• individual hypersensitivity to substances in the composition of the product;
• lactose deficiency Paw;
• impaired absorption of glucose-galactose.

Kagocel is contraindicated for women during pregnancy and breastfeeding. This remedy is considered safe, but exceeding the dose can lead to stomach pain, severe nausea, dizziness and other signs of malaise. In this case, the patient needs to drink plenty of fluids and induce vomiting.

Adverse reactions and drug interactions

Of the side effects of the drug, only a rare development of allergic reactions is known.

Kagocel combines well with other medicines that are prescribed for viral and bacterial infections. When interacting with antibiotics, immunomodulators, antiviral agents, a mutual increase in effectiveness was noted. According to the instructions, Kagocel tablets for children do not have a sedative effect.

Kagocel 12 mg - instructions for use for children

The concept of "children's Kagocel" does not exist, since a single form of release is offered for children and adults - tablets, and a single dosage of 12 mg. Adults should take more medication to achieve a therapeutic effect. The recommended regimen for taking Kagocel for adults:

1. From SARS and influenza - the first 2 days, 2 tab. three times a day, then 2 days for 1 tab. three times a day.
2. Against herpetic infections and urogenital chlamydia, take 2 tablets for 5 days. three times a day.

The pediatrician should prescribe the exact treatment regimen and dosage for the child. The maximum daily dose should not exceed 24 mg for children under 6 years old, and 36 mg over 6. The minimum dose is 12 mg every 24 hours. Before taking the medicine, you need to be sure of the viral origin of the disease. In case of bacterial infections, Kagocel has an auxiliary immunomodulatory effect without eliminating the true cause of the disease.

Kagocel syrup - instructions for use for children

Kagocel for children is not produced in the form of a syrup. The medicine is available only in tablets of 12 mg. One package contains 10 pieces.

Kagocel - instruction for children and price

The price of Kagocel for children in Russia varies from 189 to 300 rubles per package.

Kagocel with instructions for use has been recently used to treat children, but there are many reviews about it. Opinions about the effectiveness and safety of the drug in patients and doctors were divided. Of the positive aspects of using the medicine, they note:

• the tablet is very small and easy for a child to swallow;
• pills need to be taken only four days;
• there are no side reactions;
• one package of the medicine is completely enough for the entire therapeutic course for the child;
• relief of well-being occurs already on the second day of taking the medicine;
• the drug is dispensed in pharmacies without a prescription;
• in comparison with other immunomodulators, the price of Kagocel tablets for children is quite low.

For comparison, a number of drugs with a similar effect and approximate prices:

• Tamiflu - 1270 rubles;
• - 990 rubles;
• Lavomax - 690 rubles;
• Viferon - 540 rubles;
• Tsitovir-3 - 390 rubles.

Half of the patients were not satisfied with the experience of using Kagocel, even with a successful outcome of the disease.

Distrust of the drug is caused by:

1. The presence of gossypol in the medicine. This substance is obtained from cottonseed oil. It can reduce fertility in males, especially children. Gossypol is found in some male contraceptives. Since 1989, a WHO decree has banned the use of this substance in medicines. According to the manufacturer, gossypol in Kagocel is in a bound state, which ensures that it does not affect the fertility of men and boys. However, there are no studies documenting its safety.
2. Kagocel's tests were carried out only in laboratory conditions on rats. To fully prove the safety and efficacy of a substance, experiments on primates and, preferably, clinical studies are needed. They are carried out on volunteers, with the participation of a control group taking a placebo. Nothing like this was done with Kagocel.

Also, consumers were surprised by the latest metamorphosis with the drug. Previously, according to the instructions for use, Kagocel could be prescribed to children from the age of six, now it can be used from three.

According to the doctors' reviews, there is no unequivocal opinion about the instructions for using Kagocel for children. Some pediatricians trust the drug and prescribe it in combination with other medicines for the treatment of ARVI and influenza. Some of their colleagues believe that the remedy is based on the placebo effect.

According to Dr. Komarovsky, among antiviral drugs, only drugs based on oseltamivir - Tamiflu, have proven effectiveness. This active substance has undergone many laboratory and clinical studies around the world. Other medicines in this group cannot boast of a similar evidence base.

In most cases of acute respiratory viral infections and influenza, Kagocel quickly eliminates the symptoms of the disease and shortens the treatment period. Before using the product, you need to consult a pediatrician and accurately establish a diagnosis.