Cornergel instructions for use. Eye gel "Cornergel": instructions for use, composition, analogues, reviews

Preparation, stimulating regeneration processes for local applications in ophthalmology

Active substance

Release form, composition and packaging

◊ Gel eye Transparent or slightly opalescent, colorless, easily flowing.

Auxiliary substances: Caterimide - 0.1 mg, Dinatarium Edettat - 0.1 mg, carbomer - 0.1 mg, sodium hydroxide - 1.01 mg, water d / and - 945.79 mg.

5 g - tubes (1) - packs cardboard.
10 g - tubes (1) - packs cardboard.

pharmachologic effect

The acting substance of the drug Kornegel is decantenol / panthenol - the precursor of pantothenic acid, which thus has the same biological properties as D-pantothenic acid, which, turning into a person's body into a coenzyme A, is involved in many metabolic processes.

The data obtained in animal experiments indicate an increase in the proliferation of fibroblasts and the presence of a regenerating effect. In the external use of decantenol is capable of replenishing the increased need of damaged skin or mucosa in pantothenic acid.

The eye gel has a high viscosity, which allows for a long-term contact of the decantenol with the surface of the mucous membrane of the eye.

Pharmacokinetics

According to the results of the study of the decanteral labeled decantenol, its absorption is installed through skin.

To increase the duration of the contact of the aqueous solution of decantenol with the cornea epithelium in the composition of the drug Kornegel contains a carbomer, which due to the high molecular weight does not penetrate the fabric of the eyeball and is not absorbed into the systemic blood flow.

Indications

• treatment of non-inflammatory keratopathy, such as corneal dystrophy, recurrent erosion, corneal lesions when wearing contact lenses;
• as auxiliary therapy to stimulate the process of healing of the cornea and conjunctivations in their injuries and (chemical and thermal);
• as auxiliary means in the treatment of infectious damage to corneal of bacterial, viral or fungal origin.

Contraindications

• individual increased sensitivity to any of the components of the drug.

FROM caution Apply the drug and during breastfeeding period (there are no clinical data).

Dosage

Apply locally. In the lower conjunctival bag of affected eyes, you bury 1 drop 4 times / day, as well as 1 drop before bedtime.

Side effects

Local reactions: Itching, hyperemia, edema of conjunctiva, pain, feeling, strengthening of tears, transient "bold" view.

Allergic reactions:very rarely increased sensitivity (itching, rash on the skin).

Overdose

The data on the overdose of the drug is absent.

Medicinal interaction

Cases of incompatibility with other drugs are unknown.

In cases where additional local therapy is carried out by eye drops / ointments, the interval between the administration of the drug Kornergel and other ophthalmologic drugs should be at least 15 minutes.

By virtue of its physical properties, the drug Korneghel can extend the time of finding other ophthalmologic drugs on the surface of the mucous membrane of the eye and, thereby, increase their action. Therefore, the kiernegel should be applied the last.

special instructions

Cornelgel should not be used as a monotherapy of infectious damage to cornea of \u200b\u200bbacterial, viral or fungal origin.

Preservative Caterimide, which is part of the drug, with a long or too frequent application, can cause local eye irritation, allergic reactions (burning, redness, feeling of the foreign body in the eye) and damage to the corneal epithelium.

During the treatment period, the Cornershell is not recommended to carry contact lenses due to the possible incompatibility of the drug with the material of the lenses. However, if contact lenses are still shown, before applying the drug Kornegel, they should be removed and re-install no earlier than 15 minutes after the drug injection.

Do not touch the tip of pipette tubes to the eye.

Tuba must be closed after each use.

If the improvements of the state is not noted, there are signs of eye irritation, the patient should stop using the drug and seek advice from the doctor.

Impact on the ability to driving vehicles and control mechanisms

After instillation of the drug, a thin film is formed on the cornea, which can cause short-term leaning of vision, thereby reducing the reaction rate. Therefore, the management of vehicles and mechanisms should be proceeding when the clarity of vision will be restored.

Pregnancy and lactation

Data on the effects of pantothenic acid when taking inside during the course of pregnancy and the development of the fetus or the health of the newborn are absent. However, it is known that when taking inside pantothenic acid, into which decantenol is metabantized, penetrates freely through the placental barrier and is proportional to the amount of adopted drug in breast milk.

Since the data on the concentration of decantentenol (pantotenic acid) in the blood after local use in the form of an eye gel is missing, the use of the drug Cornelgel during pregnancy and / or during breastfeeding period is possible only after consulting a doctor when the expected benefit for the mother exceeds the potential risk to the fetus and / or child.

Conditions of vacation from pharmacies

The drug is released without a recipe.

Terms and Storage Terms

The drug should be stored in an inaccessible for children protected from light place at a temperature not higher than 25 ° C. Shelf life - 2 years. Do not use after the expiration date indicated on the package.

After opening the tube, the drug should be stored not more than 6 weeks.

Structure

Description of the dosage form

Transparent or slightly opaleszing colorless easily flowing gel.

pharmachologic effect

pharmachologic effect - keratoprotective, regenerating.

Pharmacodynamics

The acting substance of the drug Kornegel is decantenol / panthenol - the precursor of pantothenic acid, which thus has the same biological properties as D-pantothenic acid, which, turning into a person's body into a coenzyme A, is involved in many metabolic processes. The data obtained in animal experiments indicate an increase in the proliferation of fibroblasts and the presence of a regenerating effect. In the external use of decantenol is capable of replenishing the increased need of damaged skin or mucosa in pantothenic acid. The eye gel has a high viscosity, which allows for a long-term contact of the decantenol with the surface of the mucous membrane of the eye.

Pharmacokinetics

To increase the duration of the contact of the aqueous solution of decantenol with the cornea epithelium in the composition of the drug Kornegel contains a carbomer, which due to the high molecular weight does not penetrate the fabric of the eyeball and is not absorbed into the systemic blood flow.

Indications of the drug Cornergel

treatment of non-inflammatory keratopathy, incl. corneal dystrophy, recurrent erosion, corneal lesions when wearing contact lenses;

as auxiliary therapy to stimulate the process of healing of the cornea and conjunctivations in their injuries and burns (chemical and thermal);

as an auxiliary therapy in the treatment of infectious damage to the cornea of \u200b\u200bbacterial, viral or fungal origin.

Contraindications

Individual increased sensitivity to any of the components of the drug.

Carefully: pregnancy; Breastfeeding period (there are no clinical data).

Application in pregnancy and breastfeeding

Data on the effects of pantothenic acid when taking inside during the course of pregnancy and the development of the fetus or the health of the newborn are absent. However, it is known that when taken inside pantothenic acid, in which decantenol is metabantized, penetrates freely through the placenta and is derived from breast milk in proportion to the amount of adopted drug.

Since the data on the concentration of decantentenol (pantothenic acid) in the blood plasma after local use in the form of an eye gel is missing, the use of the drug Cornelgel during pregnancy and / or breastfeeding is possible only after consulting a doctor when the expected benefit for the mother exceeds the potential risk for the fetus and / or child.

Side effects

From the body of the vision: Itching, hyperemia, edema of conjunctiva, pain, feeling of the foreign body in the eye, strengthening of tears, transient binding of vision.

From the immune system: Very rarely - allergic reactions (itching, rash on the skin).

Interaction

Cases of incompatibility with other drugs are unknown.

In cases where additional local therapy is carried out by eye drops / ointments, the interval between the administration of the drug Kornergel and other ophthalmologic drugs should be at least 15 minutes.

By virtue of its physical properties, the drug Corneregel can extend the time of staying other ophthalmic drugs in the eye and thereby strengthen their action. Therefore, the kiernegel should be applied the last.

Method of application and dose

Conjunctivative. In the lower conjunctival bag of the affected eye, 1 drop 4 times a day, as well as 1 drop before bedtime.

Overdose

Above overdose data is absent.

special instructions

The drug Corneghel should not be used as a monotherapy of infectious damage to the cornea of \u200b\u200bbacterial, viral or fungal origin.

Preservative Caterimide, which is part of the drug, with a long or too frequent application, can cause local eye irritation, allergic reactions (burning, redness, feeling of the foreign body in the eye) and damage to the corneal epithelium.

During the treatment period, the Cornershell is not recommended to carry contact lenses due to the possible incompatibility of the drug with the material of the lenses. However, if the contact lenses are still shown, before applying the drug, they should be removed and replaced and re-put on no earlier than 15 minutes after the drug injection.

Do not touch the tip of pipette tubes to the eye.

I have so a dog in the forest at the branch of the eye of the eye, I thought there would remain without it. But nothing, also treated Korneghel, another drug (I do not remember the name) and everything healed "like on the dog." Do not even pure runs)))

The gel is cool, I have for the second day, I stopped the eye on the second day and disappeared before my eyes, and it was all because I myself accidentally got into my eyes - this is how we played with the children. And Kornergel advised me in the pharmacy, the decantenol was told there as much as possible and quickly heal. So it was.

And I have discomfort after a long wearing contact lenses, discomfort, in the eye, as if the sand was poured. But the doctor, when I picked up the lenses, immediately told about Corneghel. I use only it, as it helps so quickly and effectively. It also helps any experiments with analogues or drugs cheaper.

I treated the eye with Corneghel when a child accidentally got a toy pistol in her eye, the cornea was damaged and I honestly experienced a very experienced eye as if the eye did not see worse. But it seemed to have done, the kiernegel is well cloth restored, there is a small point, if you look closely.

I nano from time to time Cornelgel to eliminate discomfort and the sensation of sand in the eyes. It contains decantenol and copes well with the healing of the microtraums of the eye surface. Me with my hard contact lenses without this gel is nowhere. They often rub eyes.

Now in the pre-New Year Courtyard decorate the house for the holiday. So I decided to spend the books, we have a big library, there is also a grandfather began to collect. And from the very top gave a book and dust in the eyes poured. She grabbed her eyes, they root became. I went to the doctor, it turned out that somehow this dust was damaged by the surface of the eyes. The doctor recommended Kornegel five times a day to apply within a week. And he will help, literally after the first applying the eye stopped itching, and redness began to leave. And so on the week completely everything passed. But I would never have thought that ordinary dust could create such problems.

Not so long ago began to wear lenses, and faced a stack problem as a feeling of burning in the eyes. I didn't even immediately understand what happened, I turned to the doctor. He said to me that when I shot and dressed lenses, damaged the cornea of \u200b\u200bthe eyes, from here and discomfort. So appointed me to apply Cornelgel. And the truth is how it began to apply this gel, then it became much easier to the eyes, and then discomfort passed at all, the surface of the eye was restored. Now I do not run this gel as prevention at night when lenses take off.

My experience of using Cornelhegel is short, but effective. I applied to the eye after the knocked out in the forest was drunk and slightly damaged the cornea, for two weeks the use of gel and traces of damage left. Now I think that it will be necessary to keep it in the first-aid kit just for such cases.

Good tool. I always use it in the country when you need to mow, the trees will register, repair something. No, no, yes, some foreign body will fall into the eye, and the kiernegel just helps to cope with the micro-gras. Quickly quickly heals.

At all, I did not think that lenses could somehow damage the eyes. And it turned out from a long wearing the microtraums of the surface appear - here the Korneghel and he treated them, as the doctor prescribed. I have long known about Decpaantenol that it accelerates the regeneration of tissues, and then a special eye gel with this substance. I helped well.

I also began to alternate the ARTELAC drops with the Corneghel. Retrieved during the day I use the artellax drops or a splash drops, it all depends on the circumstances, and at night, when I already remove the lenses, I lay the coreghel. So now I wear lenses with comfort, there is no dryness, there is no discomfort. After Cornergel, the eyes have rested in the morning. I will continue to use such prevention methods for your eyes.

When I just began to pick myself a lenses an ophthalmologist immediately said to use the Corneghel at the slightest discomfort of the eyes, as microtraums often appear on the cornea, even from the best lenses, and then the sorinka will fall, it will start. In general, I fulfill this recommendation regularly. At the first discomfort I drip him into my eyes. But literally recently were in hot countries, there were a lot of eyes, the feeling of sand and, accordingly, pain. Cornelgel although he copes with discomfort, but he still does not moisturize drops. When they returned home, I immediately went to my doctor. She prescribed a drop of arthelak. At first, the dryness was dripped by Artelac Balan throughout the day, and then when the eyes are less than drowning will go to the artelac splash. And now advised if I'm going to the arid climate, these drops always take with you. Now there are three important bottles in my first-aid kit: Cornergel and two artellics.

Cornergel to me an ophthalmologist along with the artelek splash and artelek balance prescribed. He himself is good in itself, but with my problem, the strong sensitivity of the eyes without Arteleka can not do without any, the eyes dry out, the feeling that the sand was poured. And the glasses are not always comfortable with my scatter, and they do not go to me. So you have to get out. And lenses wear and diskship to use

How and in what dosage should I use the eye gel "Cornergel"? The instruction of this medication is presented below. We also tell you about what properties is this tool, which is included in its composition, whether it is analogues and adverse reactions, for which it is also intended.

Composition, form, description, local packaging

What substances contain "Cornergel" (gel eye)? Reviews of doctors indicate that 1 g of this drug includes 50 mg of decantenol. It also contains auxiliary ingredients in the form of sodium hydroxide, sodium edestate, purified, carbomer and zetrimide.

The white and transparent ketching gel "Cornelgel" is produced in opaque tubes of 10 or 5 g placed in cardboard packaging.

Pharmacological features

What is the eye gel "Cornergel"? Properties of this drug are similar to the properties of pantothenic acid. However, unlike her, the active substance of the medication under consideration deeper and faster penetrates into the fabric of the eye.

According to the attached instruction, this dermatoprotective agent has anti-inflammatory activity. After applying, it contributes to the regeneration of the mucous membrane and eye tissues. The active medication component compensates for the need of damaged tissues in pantothenic acid (in the form of coenzyme A).

Pharmacokinetics of the local drug

Due to its dosage form, the eye gel "Cornergel" does not penetrate into also it is not absorbed into systemic bloodstream, but quite a long time is on the surface of the affected area and is practically not washed with water.

Indications for use

Corneghel is an eye gel, which is actively used in ophthalmological practice. According to those skilled in the art, this drug is very effective. As a rule, it is prescribed at:

• keratitis;
• damage to the cornea, which manifests itself in the form of erosion;
• conjunctivitis;
• dystrophic corneal diseases;
• eye burns of various types;
• infectious diseases.

In addition to the above, it should be noted that the ocular gel "Cornergel" is often used as a prophylactic agent with a debt wearing contact lenses.

Contraindications for use

What states are contraindications to the use of this fund? It is prohibited to be used in allergies or intolerance to the basic and additional substances of the drug.

It should also be noted that it is necessary to exercise special caution to people with renal failure flowing in hard form, as well as nursing mothers and pregnant women.

"Cornergel" (gel eye): instructions for use

Before using this drug, it is necessary to study the attached instructions. This is due primarily to the fact that it has a number of side effects. We will tell you a little further about them.

According to the specialists, the Eye Gel "Cornergel" must be used from three to five times a day. The drug is prescribed one drop. And the gel is applied directly under the conjunctival bag.

If you use any other eye medications, the interval between their receptions must be at least five minutes. At the same time, the eye gel must be applied to the latter.

As mentioned above, this drug is often used for prevention with a debt wearing contact lenses. If you use this tool for these purposes, you should know that before applying the lens medication, it is necessary to remove and put on after an hour.

Adverse Reactions After using the drug

Usually the eye gel "Corneghel" is transferred to patients well enough. However, in some cases, people may have such unwanted reactions like redness of the eyes, discomfort and a feeling of burning. In addition, this drug may cause allergic spindles on the skin.

Often, patients complain about blurred vision, which manifests itself immediately applying the drug.

Experts argue that when such symptoms appear, the use of the drug should be discontinued. In this case, they recommend contacting the doctor, which is obliged to replace the medication more secure.

Cases overdose

In the instructions there are no information about the cases of overdose by the drug "Cornergel". However, this fact does not mean that the eye gel can be used in any quantity and with any frequency. Only the doctor strictly according to the testimony should be assigned it.

Medicinal interaction

The drug interaction of this drug is not investigated enough. To date, no undesirable phenomena after the use of several medications has not at the same time. However, experts still require an observance of a 15-minute interval between local use of other medicines for the eyes. Moreover, Cornergel should be applied to the latter.

drug, conditions for its sale and storage

A gel for the eye "Cornergel" is free, that is, it can be purchased without a medical recipe. It should be stored in a dark cool place protected from children. The shelf life of the local drug is two years. However, after opening a drug substance tube, this period is reduced to six weeks. After the specified time, use the eye medication is not recommended.

During the treatment with this drug undesirable to wear soft contact lenses. Before applying the drug, they should be removed and not to be installed within 15 minutes after the instillation of the medication.

After each use of gel-like droplets, the tube must immediately close. At the same time, it is extremely not recommended to touches it with the tip to the eye.

During the treatment period, the patient needs to refrain from driving vehicles, as well as on hazardous activities, which require the speed of psychomotor reactions, the clarity of vision and increased concentration of attention.

Is it possible to use children?

According to the attached instructions, the Eye Gel "Cornergel" for children is absolutely harmless. The kids are prescribed by the same testimony as for adults. The drug dosage is chosen individually, but, as a rule, it is one drop twice or three times a day.

Similar drugs and local price

If it is impossible to use the drug under consideration (for example, with intolerance of the main and auxiliary substances, as well as with allergic reactions), it is possible to apply its analogue. "Cornergel" is an eye gel, which has many substitutes. The closest analogues of this drug are such medicines as "Sicaprotect", Pantecret, Pantexol, Hebiderm, "Depantola", Panthenol, Bepanten.

It should also be noted that it is possible to replace the "Cornergel" with the following drugs: "Fanks", "Arttelak", "Solkosaryl", "Vodikik", "Taufon", "Kaliya Yodide", "Sicapos", "Lipoflavon", "Wholetolic", "Wheel Dressers", "Ophthalmol", "Artificial Tears", "Optiv", "Okafernon", "Quinks".

As for the price, this means it can be different. It depends on the region and markup of the pharmacy network. Also the cost of the drug is determined by its volume. For example, 5 g tube with eye gel can be purchased for 280-290 rubles, and 10 g - for 340-350 rubles.

Cornergel®

International UnPatented Name:

Decispantenol

Dosage form:

gel eye

Structure

1 g gel contains:

Active substance:
Decantenol 50.00 mg
Excipients:
Catermide 0.10 mg, Dinatarium Edetate 0.10 mg, CarBeryer 0.10 mg, sodium hydroxide 1.01 mg, water for injection 945.79 mg.

Description:

transparent or slightly opaleszing colorless easily flowing gel.

Pharmacotherapeutic Group:

reparations of fabrics stimulant

ATX code:

Pharmacological properties:

Pharmacodynamics
The active substance of the drug Corneghel® is decantenol / Panthenol - a pantothenic acid process that has all the same biological properties as D-pantothenic acid, which, turning into a person's body in a coenzyme A, is involved in many metabolic processes. The data obtained in animal experiments indicate an increase in the proliferation of fibroblasts and the presence of a regenerating effect. In the external use of decantenol is capable of replenishing the increased need of damaged skin or mucosa in pantothenic acid. The eye gel has a high viscosity, which allows for a long-term contact of the decantenol with the surface of the mucous membrane of the eye.

Pharmacokinetics
According to the results of the study of the declaration of decantenol labeled, its penetration (adsorption) is established through skin cover.

To increase the duration of the contact of the an aqueous solution of decantenol with the cornea epithelium in the composition of the drug Cornergel®, contains a carbomer, which due to the high molecular weight does not penetrate the fabric of the eyeball and is not absorbed into the systemic blood flow.

Indications for use:

Treatment of keratopathy of not inflammatory character, for example, such as: corneal dystrophy, recurrent erosion, damage to the cornea when wearing contact lenses.
- As auxiliary therapy for stimulating the process of healing of the cornea and conjunctiva in their injuries and burns (chemical and thermal).
- auxiliary agent in the treatment of infectious damage to corneal of bacterial, viral or fungal origin.

Contraindications:

Individual increased sensitivity to any of the components of the drug.

Carefully:

During pregnancy and in breastfeeding period (there are no clinical data).

Pregnancy and breastfeeding period:

Data on the effects of pantothenic acid when taking inside during the course of pregnancy and the development of the fetus or the health of the newborn are absent. However, it is known that when taking into the pantothenic acid, into which the decantenol metabhanizes, freely penetrates through the placenta and is derived from breast milk in proportion to the amount of received drug.

Since data on the concentration of decantenten (pantotenic acid) in the blood plasma after local application in the form of an eye gel is missing, the use of the drug Cornergel® during pregnancy and / or breastfeeding is possible only after consulting a doctor when the expected benefit for the mother exceeds the potential risk to the fetus and / or child.

Method of use and dose:

Locally.
In the lower conjunctival bag of the affected eye, 1 drop 4 times a day, as well as 1 drop before bedtime.

Side effect:

Itching, hyperemia, edema of conjunctiva, pain, feeling of "foreign body", strengthening tears, transient "bold" view.
Allergic reactions: very rarely increased sensitivity (itching, rash on the skin.

Overdose:

Above the overdose data is absent.

Interaction with other drugs:

Cases of incompatibility with other drugs are unknown.
In cases where additional local therapy is carried out by eye drops / ointments, the interval between the introduction of the drug Cornergel® and other ophthalmological preparations should be at least 15 minutes.
By virtue of its physical properties, the drug Corneghel® can extend the time of stay of other ophthalmological preparations in the eye and, thereby strengthening their action. Therefore, Cornergel® should be applied last.

Special instructions:

Cornergel® should not be used as a monotherapy of infectious damage to the cornea of \u200b\u200bbacterial, viral or fungal origin.

Preservative Caterimide, which is part of the drug, with a long or too frequent use, can cause local eye irritation, allergic reactions (burning, redness, feeling of the "foreign body" in the eye) and damage to the corneal epithelium.

During the treatment of Cornergel®, wearing contact lenses are not recommended, due to the possible incompatibility of the drug with the material of the lenses. However, if contact lenses are still shown, before applying the drug Cornergel®, they should be removed and re-put on no earlier than 15 minutes after the drug.

Do not touch the tip of pipette tubes to the eye.

Tuba must be closed after each use.

If the condition improvements are not noted, there are signs of eye irritation, it is necessary to stop the use of the drug and seek advice from the doctor.

Impact on the ability to control vehicles and complex mechanisms
After instillation of the drug, a thin film is formed on the cornea, which can cause a short-term "bold" of view, thereby reducing the reaction rate. Therefore, the management of vehicles and mechanisms should be proceeding when the clarity of vision will be restored.

Release form:

Gel eye 5%.
5 g or 10 g in tube with a head with a nozzle and a screwdriver cap from PVP.
1 tube along with medical application instructions in a cardboard pack.

Shelf life:

2 years.
After opening the tube to store not more than 6 weeks.
Do not use after the expiration date indicated on the package.

Storage conditions:

In the place protected from light, at a temperature not higher than 25 ° C.
Keep out of the reach of children.

Leave terms:

Without recipe.

Manufacturer (all stages):

Dr. Gerhard Mann, chemical-pharmaceutical enterprise GmbH, Germany
Brunsbutteler Damm 165-173, 13581 Berlin /
Dr. Gerhard Mann Chem. - Pharm. Fabrik Gmbh.
BRUNSBUTTERER DAMM 165-173, 13581 BERLIN.

You can get more information about the drug, as well as send your claims and information about undesirable phenomena at the following address in Russia:
Baush & Lomb LLC
Russia, 115191, Moscow, ul. Large Tula, d. 11.
Recording Manager "Baush & Lomb"